Response to Comment on "Ghost cytometry"

Di Carlo et al. comment that our original results were insufficient to prove that the ghost cytometry technique is performing a morphologic analysis of cells in flow. We emphasize that the technique is primarily intended to acquire and classify morphological information of cells in a computationally efficient manner without reconstructing images. We provide additional supporting information, including images reconstructed from the compressive waveforms and a discussion of current and future throughput potentials. Ghost cytometry (GC) performs a direct analysis of compressive imaging waveforms and thereby substantially relieves the computational bottleneck hindering the realization of high-throughput cytometry based on morphological information (1). The comments by Di Carlo et al. argue against a number of our conclusions (2), but given the restricted length allowed for this response, we will address what we consider the most important points.