The Sigmoid Nonlinearity in Prepyriform Cortex

THE SIGMOID NONLINEARITY IN PREPYRIFORM CORTEX Frank H. Eeckman University of California, Berkeley, CA 94720 ABSlRACT We report a study ·on the relationship between EEG amplitude values and unit spike output in the prepyriform cortex of awake and motivated rats. This relationship takes the form of a sigmoid curve, that describes normalized pulse-output for normalized wave input. The curve is fitted using nonlinear regression and is described by its slope and maximum value. Measurements were made for both excitatory and inhibitory neurons in the cortex. These neurons are known to form a monosynaptic negative feedback loop. Both classes of cells can be described by the same parameters.