Exact Bayesian inference for off-line change-point detection in tree-structured graphical models

L. Schwaller · S. Robin Abstract We consider the problem of change-point detection in multivariate time-series. The multivariate distribution of the observations is supposed to follow a graphical model, whose graph and parameters are affected by abrupt changes throughout time. We demonstrate that it is possible to perform exact Bayesian inference whenever one considers a simple class of undirected graphs called spanning trees as possible structures. We are then able to integrate on the graph and segmentation spaces at the same time by combining classical dynamic programming with algebraic results pertaining to spanning trees. In particular, we show that quantities such as posterior distributions for change-points or posterior edge probabilities over time can efficiently be obtained. We illustrate our results on both synthetic and experimental data arising from biology and neuroscience. Keywords change-point detection, exact Bayesian inference, graphical model, multivariate time-series, spanning tree 1 Introduction We are interested in time-series data where several variables are observed throughout time. An assumption often made in multivariate settings is that there exists an underlying network describing the dependences between the different variables. When modelling time-series data, one is faced with a choice: shall this network be considered stationary or not? Taking the example of genomic data, it might for instance be un-L. This network might slowly evolve, or undergo abrupt changes leading to the initialisation of new morphological development stages in the organism of interest. Here, we focus our interest on the second scenario. The inference of the dependence structure ruling a multivariate time-series was first performed under the assumption that this structure was stationary ( e.g.