Uncertainty
"AI systems–like people–must often act despite partial and uncertain information. First, the information received may be unreliable (e.g., a patient may mis-remember when a disease started, or may not have noticed a symptom that is important to a diagnosis). In addition, rules connecting real-world events can never include all the factors that might determine whether their conclusions really apply (e.g., the correctness of basing a diagnosis on a lab test depends whether there were conditions that might have caused a false positive, on the test being done correctly, on the results being associated with the right patient, etc.) Thus in order to draw useful conclusions, AI systems must be able to reason about the probability of events, given their current knowledge."
– from David Leake, Reasoning Under Uncertainty
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Generalized Bayesian Inference for Scientific Simulators via Amortized Cost Estimation Richard Gao
Neural Information Processing Systems
Simulation-based inference (SBI) enables amortized Bayesian inference for simulators with implicit likelihoods. But when we are primarily interested in the quality of predictive simulations, or when the model cannot exactly reproduce the observed data (i.e., is misspecified), targeting the Bayesian posterior may be
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