In this work we present a review of the state of the art of Learning Vector Quantization (LVQ) classifiers. A taxonomy is proposed which integrates the most relevant LVQ approaches to date. The main concepts associated with modern LVQ approaches are defined. A comparison is made among eleven LVQ classifiers using one real-world and two artificial datasets.

Traditionally, there are three species of classification: unsupervised, supervised, and semi-supervised. Supervised and semi-supervised classification differ by whether or not weight is given to unlabelled observations in the classification procedure. In unsupervised classification, or clustering, all observations are unlabeled and hence full weight is given to unlabelled observations. When some observations are unlabelled, it can be very difficult to \textit{a~priori} choose the optimal level of supervision, and the consequences of a sub-optimal choice can be non-trivial. A flexible fractionally-supervised approach to classification is introduced, where any level of supervision --- ranging from unsupervised to supervised --- can be attained. Our approach uses a weighted likelihood, wherein weights control the relative role that labelled and unlabelled data have in building a classifier. A comparison between our approach and the traditional species is presented using simulated and real data. Gaussian mixture models are used as a vehicle to illustrate our fractionally-supervised classification approach; however, it is broadly applicable and variations on the postulated model can be easily made.

Since these data are typically sampled from multi-modal distributions, a natural choice would be using nonparametric density estimation methods. Classic empirical distribution (ED) and kernel density estimation (KDE) play an important role in nonparametric density estimation. Besides their long noticed drawbacks (e.g., ED is noncontinuous; KDE is sensitive to the choice of bandwidth and scales poorly in high dimensions), they are not good summarization tools in dealing with data with high dimension and large size, e.g., evaluating them involves each data point and their functional forms provide little direct information of the "landscape" of the distribution. In this paper, we consider domain partition based approach for density estimation. The use of domain partition dates back to histogram, which is still an ubiquitous tool in data analysis today; however, its non-scalability in high dimensions limits its applications. Motivated by the usefulness of histogram and the attempts to adapt it for multivariate cases, we propose a novel nonparametric density estimation method.

In this paper, several modifications are introduced to the functional approximation method iterLap to reduce the approximation error, including stopping rule adjustment, proposal of new residual function, starting point selection for numerical optimisation, scaling of Hessian matrix. Illustrative examples are also provided to show the trade-off between running time and accuracy of the original and modified methods.

We consider the problem of group testing with sum observations and noiseless answers, in which we aim to locate multiple objects by querying the number of objects in each of a sequence of chosen sets. We study a probabilistic setting with entropy loss, in which we assume a joint Bayesian prior density on the locations of the objects and seek to choose the sets queried to minimize the expected entropy of the Bayesian posterior distribution after a fixed number of questions. We present a new non-adaptive policy, called the dyadic policy, show it is optimal among non-adaptive policies, and is within a factor of two of optimal among adaptive policies. This policy is quick to compute, its nonadaptive nature makes it easy to parallelize, and our bounds show it performs well even when compared with adaptive policies. We also study an adaptive greedy policy, which maximizes the one-step expected reduction in entropy, and show that it performs at least as well as the dyadic policy, offering greater query efficiency but reduced parallelism. Numerical experiments demonstrate that both procedures outperform a divide-and-conquer benchmark policy from the literature, called sequential bifurcation, and show how these procedures may be applied in a stylized computer vision problem.

We propose a Conditional Density Filtering (C-DF) algorithm for efficient online Bayesian inference. C-DF adapts MCMC sampling to the online setting, sampling from approximations to conditional posterior distributions obtained by propagating surrogate conditional sufficient statistics (a function of data and parameter estimates) as new data arrive. These quantities eliminate the need to store or process the entire dataset simultaneously and offer a number of desirable features. Often, these include a reduction in memory requirements and runtime and improved mixing, along with state-of-the-art parameter inference and prediction. These improvements are demonstrated through several illustrative examples including an application to high dimensional compressed regression. Finally, we show that C-DF samples converge to the target posterior distribution asymptotically as sampling proceeds and more data arrives.

A fundamental aspect of biological information processing is the ubiquity of sequence-function relationships -- functions that map the sequence of DNA, RNA, or protein to a biochemically relevant activity. Most sequence-function relationships in biology are quantitative, but only recently have experimental techniques for effectively measuring these relationships been developed. The advent of such "massively parallel" experiments presents an exciting opportunity for the concepts and methods of statistical physics to inform the study of biological systems. After reviewing these recent experimental advances, we focus on the problem of how to infer parametric models of sequence-function relationships from the data produced by these experiments. Specifically, we retrace and extend recent theoretical work showing that inference based on mutual information, not the standard likelihood-based approach, is often necessary for accurately learning the parameters of these models. Closely connected with this result is the emergence of "diffeomorphic modes" -- directions in parameter space that are far less constrained by data than likelihood-based inference would suggest. Analogous to Goldstone modes in physics, diffeomorphic modes arise from an arbitrarily broken symmetry of the inference problem. An analytically tractable model of a massively parallel experiment is then described, providing an explicit demonstration of these fundamental aspects of statistical inference. This paper concludes with an outlook on the theoretical and computational challenges currently facing studies of quantitative sequence-function relationships.

Classification is an important tool with many useful applications. Among the many classification methods, Fisher's Linear Discriminant Analysis (LDA) is a traditional model-based approach which makes use of the covariance information. However, in the high-dimensional, low-sample size setting, LDA cannot be directly deployed because the sample covariance is not invertible. While there are modern methods designed to deal with high-dimensional data, they may not fully use the covariance information as LDA does. Hence in some situations, it is still desirable to use a model-based method such as LDA for classification. This article exploits the potential of LDA in more complicated data settings. In many real applications, it is costly to manually place labels on observations; hence it is often that only a small portion of labeled data is available while a large number of observations are left without a label. It is a great challenge to obtain good classification performance through the labeled data alone, especially when the dimension is greater than the size of the labeled data. In order to overcome this issue, we propose a semi-supervised sparse LDA classifier to take advantage of the seemingly useless unlabeled data. They provide additional information which helps to boost the classification performance in some situations. A direct estimation method is used to reconstruct LDA and achieve the sparsity; meanwhile we employ the difference-convex algorithm to handle the non-convex loss function associated with the unlabeled data. Theoretical properties of the proposed classifier are studied. Our simulated examples help to understand when and how the information extracted from the unlabeled data can be useful. A real data example further illustrates the usefulness of the proposed method.

Ensembles of climate models are commonly used to improve climate predictions and assess the uncertainties associated with them. Weighting the models according to their performances holds the promise of further improving their predictions. Here, we use an ensemble of decadal climate predictions to demonstrate the ability of sequential learning algorithms (SLAs) to reduce the forecast errors and reduce the uncertainties. Three different SLAs are considered, and their performances are compared with those of an equally weighted ensemble, a linear regression and the climatology. Predictions of four different variables--the surface temperature, the zonal and meridional wind, and pressure--are considered. The spatial distributions of the performances are presented, and the statistical significance of the improvements achieved by the SLAs is tested. Based on the performances of the SLAs, we propose one to be highly suitable for the improvement of decadal climate predictions.

Gathering the most information by picking the least amount of data is a common task in experimental design or when exploring an unknown environment in reinforcement learning and robotics. A widely used measure for quantifying the information contained in some distribution of interest is its entropy. Greedily minimizing the expected entropy is therefore a standard method for choosing samples in order to gain strong beliefs about the underlying random variables. We show that this approach is prone to temporally getting stuck in local optima corresponding to wrongly biased beliefs. We suggest instead maximizing the expected cross entropy between old and new belief, which aims at challenging refutable beliefs and thereby avoids these local optima. We show that both criteria are closely related and that their difference can be traced back to the asymmetry of the Kullback-Leibler divergence. In illustrative examples as well as simulated and real-world experiments we demonstrate the advantage of cross entropy over simple entropy for practical applications.