Exponential families are widely used in machine learning; they include many distributions in continuous and discrete domains (e.g., Gaussian, Dirichlet, Poisson, and categorical distributions via the softmax transformation). Distributions in each of these families have fixed support. In contrast, for finite domains, there has been recent works on sparse alternatives to softmax (e.g. sparsemax, $\alpha$-entmax, and fusedmax) and corresponding losses, which have varying support. This paper expands that line of work in several directions: first, it extends $\Omega$-regularized prediction maps and Fenchel-Young losses to arbitrary domains (possibly countably infinite or continuous). For linearly parametrized families, we show that minimization of Fenchel-Young losses is equivalent to moment matching of the statistics, generalizing a fundamental property of exponential families. When $\Omega$ is a Tsallis negentropy with parameter $\alpha$, we obtain "deformed exponential families," which include $\alpha$-entmax and sparsemax ($\alpha$ = 2) as particular cases. For quadratic energy functions in continuous domains, the resulting densities are $\beta$-Gaussians, an instance of elliptical distributions that contain as particular cases the Gaussian, biweight, triweight and Epanechnikov densities, and for which we derive closed-form expressions for the variance, Tsallis entropy, and Fenchel-Young loss. When $\Omega$ is a total variation or Sobolev regularizer, we obtain a continuous version of the fusedmax. Finally, we introduce continuous-domain attention mechanisms, deriving efficient gradient backpropagation algorithms for $\alpha \in \{1, 4/3, 3/2, 2\}$. Using them, we demonstrate our sparse continuous distributions for attention-based audio classification and visual question answering, showing that they allow attending to time intervals and compact regions.

In this work we continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT. In particular, we consider a scenario when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the recently proposed nonparametric posterior learning technique to the context of Poisson-type data in emission tomography. Using this approach we derive sampling algorithms which are trivially parallelizable, scalable and very easy to implement. In addition, we prove conditional consistency and tightness for the distribution of produced samples in the small noise limit (i.e., when the acquisition time tends to infinity) and derive new geometrical and necessary condition on how MRI images must be used. This condition arises naturally in the context of misspecified generalized Poisson models. We also contrast our approach with bayesian MCMC sampling based one one data augmentation scheme which is very popular in the context of EM-type algorithms for PET or SPECT. We show theoretically and also numerically that such data augmentation significantly increases mixing times for the Markov chain. In view of this, our algorithms seem to give a reasonable trade-off between design complexity, scalability, numerical load and asessement for the uncertainty quantification.

The field of artificial intelligence (AI) is witnessing a recent upsurge in research, tools development, and deployment of applications. Multiple software companies are shifting their focus to developing intelligent systems; and many others are deploying AI paradigms to their existing processes. In parallel, the academic research community is injecting AI paradigms to provide solutions to traditional engineering problems. Similarly, AI has evidently been proved useful to software engineering (SE). When one observes the SE phases (requirements, design, development, testing, release, and maintenance), it becomes clear that multiple AI paradigms (such as neural networks, machine learning, knowledge-based systems, natural language processing) could be applied to improve the process and eliminate many of the major challenges that the SE field has been facing. This survey chapter is a review of the most commonplace methods of AI applied to SE. The review covers methods between years 1975-2017, for the requirements phase, 46 major AI-driven methods are found, 19 for design, 15 for development, 68 for testing, and 15 for release and maintenance. Furthermore, the purpose of this chapter is threefold; firstly, to answer the following questions: is there sufficient intelligence in the SE lifecycle? What does applying AI to SE entail? Secondly, to measure, formulize, and evaluate the overlap of SE phases and AI disciplines. Lastly, this chapter aims to provide serious questions to challenging the current conventional wisdom (i.e., status quo) of the state-of-the-art, craft a call for action, and to redefine the path forward.

The power system is undergoing rapid evolution with the roll-out of advanced metering infrastructure and local energy applications (e.g. electric vehicles) as well as the increasing penetration of intermittent renewable energy at both transmission and distribution level, which characterizes the peak load demand with stronger randomness and less predictability and therefore poses a threat to the power grid security. Since storing large quantities of electricity to satisfy load demand is neither economically nor environmentally friendly, effective peak demand management strategies and reliable peak load forecast methods become essential for optimizing the power system operations. To this end, this paper provides a timely and comprehensive overview of peak load demand forecast methods in the literature. To our best knowledge, this is the first comprehensive review on such topic. In this paper we first give a precise and unified problem definition of peak load demand forecast. Second, 139 papers on peak load forecast methods were systematically reviewed where methods were classified into different stages based on the timeline. Thirdly, a comparative analysis of peak load forecast methods are summarized and different optimizing methods to improve the forecast performance are discussed. The paper ends with a comprehensive summary of the reviewed papers and a discussion of potential future research directions.

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful experimental approach to study cellular heterogeneity. One of the challenges in scRNA-seq data analysis is integrating different types of biological data to consistently recognize discrete biological functions and regulatory mechanisms of cells, such as transcription factor activities and gene regulatory networks in distinct cell populations. We have developed an approach to infer transcription factor activities from scRNA-seq data that leverages existing biological data on transcription factor binding sites. We show that the inferred transcription factor activities for key cell types identify regulatory transcription factors that are known to mechanistically control cell function and cell fate. The BITFAM approach not only identifies biologically meaningful transcription factor activities, but also provides valuable insights into underlying transcription factor regulatory mechanisms.

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The problem of domain adaptation conventionally considers the setting where a source domain has plenty of labeled data, and a target domain (with a different data distribution) has plenty of unlabeled data but none or very limited labeled data. In this paper, we address the setting where the target domain has only limited labeled data from a distribution that is expected to change frequently. We first propose a fast and light-weight method for adapting a Gaussian mixture density network (MDN) using only a small set of target domain samples. This method is well-suited for the setting where the distribution of target data changes rapidly (e.g., a wireless channel), making it challenging to collect a large number of samples and retrain. We then apply the proposed MDN adaptation method to the problem of end-of-end learning of a wireless communication autoencoder. A communication autoencoder models the encoder, decoder, and the channel using neural networks, and learns them jointly to minimize the overall decoding error rate. However, the error rate of an autoencoder trained on a particular (source) channel distribution can degrade as the channel distribution changes frequently, not allowing enough time for data collection and retraining of the autoencoder to the target channel distribution. We propose a method for adapting the autoencoder without modifying the encoder and decoder neural networks, and adapting only the MDN model of the channel. The method utilizes feature transformations at the decoder to compensate for changes in the channel distribution, and effectively present to the decoder samples close to the source distribution. Experimental evaluation on simulated datasets and real mmWave wireless channels demonstrate that the proposed methods can quickly adapt the MDN model, and improve or maintain the error rate of the autoencoder under changing channel conditions.

Tensor models play an increasingly prominent role in many fields, notably in machine learning. In several applications of such models, such as community detection, topic modeling and Gaussian mixture learning, one must estimate a low-rank signal from a noisy tensor. Hence, understanding the fundamental limits and the attainable performance of estimators of that signal inevitably calls for the study of random tensors. Substantial progress has been achieved on this subject thanks to recent efforts, under the assumption that the tensor dimensions grow large. Yet, some of the most significant among these results--in particular, a precise characterization of the abrupt phase transition (in terms of signal-to-noise ratio) that governs the performance of the maximum likelihood (ML) estimator of a symmetric rank-one model with Gaussian noise--were derived on the basis of statistical physics ideas, which are not easily accessible to non-experts. In this work, we develop a sharply distinct approach, relying instead on standard but powerful tools brought by years of advances in random matrix theory. The key idea is to study the spectra of random matrices arising from contractions of a given random tensor. We show how this gives access to spectral properties of the random tensor itself. In the specific case of a symmetric rank-one model with Gaussian noise, our technique yields a hitherto unknown characterization of the local maximum of the ML problem that is global above the phase transition threshold. This characterization is in terms of a fixed-point equation satisfied by a formula that had only been previously obtained via statistical physics methods. Moreover, our analysis sheds light on certain properties of the landscape of the ML problem in the large-dimensional setting. Our approach is versatile and can be extended to other models, such as asymmetric, non-Gaussian and higher-order ones.

This survey gives an overview of Monte Carlo methodologies using surrogate models, for dealing with densities which are intractable, costly, and/or noisy. This type of problem can be found in numerous real-world scenarios, including stochastic optimization and reinforcement learning, where each evaluation of a density function may incur some computationally-expensive or even physical (real-world activity) cost, likely to give different results each time. The surrogate model does not incur this cost, but there are important trade-offs and considerations involved in the choice and design of such methodologies. We classify the different methodologies into three main classes and describe specific instances of algorithms under a unified notation. A modular scheme which encompasses the considered methods is also presented. A range of application scenarios is discussed, with special attention to the likelihood-free setting and reinforcement learning. Several numerical comparisons are also provided.

Datasets are rarely a realistic approximation of the target population. Say, prevalence is misrepresented, image quality is above clinical standards, etc. This mismatch is known as sampling bias. Sampling biases are a major hindrance for machine learning models. They cause significant gaps between model performance in the lab and in the real world. Our work is a solution to prevalence bias. Prevalence bias is the discrepancy between the prevalence of a pathology and its sampling rate in the training dataset, introduced upon collecting data or due to the practioner rebalancing the training batches. This paper lays the theoretical and computational framework for training models, and for prediction, in the presence of prevalence bias. Concretely a bias-corrected loss function, as well as bias-corrected predictive rules, are derived under the principles of Bayesian risk minimization. The loss exhibits a direct connection to the information gain. It offers a principled alternative to heuristic training losses and complements test-time procedures based on selecting an operating point from summary curves. It integrates seamlessly in the current paradigm of (deep) learning using stochastic backpropagation and naturally with Bayesian models.