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Toward a Surgeon-in-the-Loop Ophthalmic Robotic Apprentice using Reinforcement and Imitation Learning

arXiv.org Artificial Intelligence

Robotic-assisted surgical systems have demonstrated significant potential in enhancing surgical precision and minimizing human errors. However, existing systems lack the ability to accommodate the unique preferences and requirements of individual surgeons. Additionally, they primarily focus on general surgeries (e.g., laparoscopy) and are not suitable for highly precise microsurgeries, such as ophthalmic procedures. Thus, we propose a simulation-based image-guided approach for surgeon-centered autonomous agents that can adapt to the individual surgeon's skill level and preferred surgical techniques during ophthalmic cataract surgery. Our approach utilizes a simulated environment to train reinforcement and imitation learning agents guided by image data to perform all tasks of the incision phase of cataract surgery. By integrating the surgeon's actions and preferences into the training process with the surgeon-in-the-loop, our approach enables the robot to implicitly learn and adapt to the individual surgeon's unique approach through demonstrations. This results in a more intuitive and personalized surgical experience for the surgeon. Simultaneously, it ensures consistent performance for the autonomous robotic apprentice. We define and evaluate the effectiveness of our approach using our proposed metrics; and highlight the trade-off between a generic agent and a surgeon-centered adapted agent. Moreover, our approach has the potential to extend to other ophthalmic surgical procedures, opening the door to a new generation of surgeon-in-the-loop autonomous surgical robots. We provide an open-source simulation framework for future development and reproducibility.


DeepEMplanner: An End-to-End EM Motion Planner with Iterative Interactions

arXiv.org Artificial Intelligence

Motion planning is a computational problem that finds a sequence of valid trajectories, often based on surrounding agents' forecasting, environmental understanding, and historical and future contexts. It can also be viewed as a game in which agents continuously plan their next move according to other agents' intentions and the encountering environment, further achieving their ultimate goals through incremental actions. To model the dynamic planning and interaction process, we propose a novel framework, DeepEMplanner, which takes the stepwise interaction into account for fine-grained behavior learning. The ego vehicle maximizes each step motion to reach its eventual driving outcome based on the stepwise expectation from agents and its upcoming road conditions. On the other hand, the agents also follow the same philosophy to maximize their stepwise behavior under the encountering environment and the expectations from ego and other agents. Our DeepEMplanner models the interactions among ego, agents, and the dynamic environment in an autoregressive manner by interleaving the Expectation and Maximization processes. Further, we design ego-to-agents, ego-to-map, and ego-to-BEV interaction mechanisms with hierarchical dynamic key objects attention to better model the interactions. Experiments on the nuScenes benchmark show that our approach achieves state-of-the-art results.


Reasoning with the Theory of Mind for Pragmatic Semantic Communication

arXiv.org Artificial Intelligence

In this paper, a pragmatic semantic communication framework that enables effective goal-oriented information sharing between two-intelligent agents is proposed. In particular, semantics is defined as the causal state that encapsulates the fundamental causal relationships and dependencies among different features extracted from data. The proposed framework leverages the emerging concept in machine learning (ML) called theory of mind (ToM). It employs a dynamic two-level (wireless and semantic) feedback mechanism to continuously fine-tune neural network components at the transmitter. Thanks to the ToM, the transmitter mimics the actual mental state of the receiver's reasoning neural network operating semantic interpretation. Then, the estimated mental state at the receiver is dynamically updated thanks to the proposed dynamic two-level feedback mechanism. At the lower level, conventional channel quality metrics are used to optimize the channel encoding process based on the wireless communication channel's quality, ensuring an efficient mapping of semantic representations to a finite constellation. Additionally, a semantic feedback level is introduced, providing information on the receiver's perceived semantic effectiveness with minimal overhead. Numerical evaluations demonstrate the framework's ability to achieve efficient communication with a reduced amount of bits while maintaining the same semantics, outperforming conventional systems that do not exploit the ToM-based reasoning.


Swarm Synergy: A Silent Way of Forming Community

arXiv.org Artificial Intelligence

In this paper, we introduce a novel swarm application, swarm synergy, where robots in a swarm intend to form communities. Each robot is considered to make independent decisions without any communication capability (silent agent). The proposed algorithm is based on parameters local to individual robots. Engaging scenarios are studied where the silent robots form communities without the preset conditions on the number of communities, community size, goal location of each community, and specific members in the community. Our approach allows silent robots to achieve this self-organized swarm behavior using only sensory inputs from the environment. The algorithm facilitates the formation of multiple swarm communities at arbitrary locations with unspecified goal locations. We further infer the behavior of swarm synergy to ensure the anonymity/untraceability of both robots and communities. The robots intend to form a community by sensing the neighbors, creating synergy in a bounded environment. The time to achieve synergy depends on the environment boundary and the onboard sensor's field of view. Compared to the state-of-art with similar objectives, the proposed communication-free swarm synergy shows comparative time to synergize with untraceability features.


mango: A Modular Python-Based Agent Simulation Framework

arXiv.org Artificial Intelligence

Agent-based simulations, especially those including communication, are complex to model and execute. To help researchers deal with this complexity and to encourage modular and maintainable research software, the Python-based framework mango (modular python agent framework) has been developed. The framework enables users to quickly implement software agents with different communication protocols (e.g., TCP) and message codecs (e.g., JSON). Furthermore, mango provides various options for developing an integrated agent simulation. This includes a scheduler module, which can control the agents' tasks, a (distributed) clock mechanism for time synchronization, and a specific simulation component, which can be coupled with other (co-)simulation software. These features are complemented by modular implementation patterns and a well-evaluated performance with the ability to simulate across multiple processes to ensure scalability.


Are we going MAD? Benchmarking Multi-Agent Debate between Language Models for Medical Q&A

arXiv.org Artificial Intelligence

Recent advancements in large language models (LLMs) underscore their potential for responding to medical inquiries. However, ensuring that generative agents provide accurate and reliable answers remains an ongoing challenge. In this context, multi-agent debate (MAD) has emerged as a prominent strategy for enhancing the truthfulness of LLMs. In this work, we provide a comprehensive benchmark of MAD strategies for medical Q&A, along with open-source implementations. This explores the effective utilization of various strategies including the trade-offs between cost, time, and accuracy. We build upon these insights to provide a novel debate-prompting strategy based on agent agreement that outperforms previously published strategies on medical Q&A tasks.


Guarantees for Self-Play in Multiplayer Games via Polymatrix Decomposability

arXiv.org Artificial Intelligence

Self-play is a technique for machine learning in multi-agent systems where a learning algorithm learns by interacting with copies of itself. Self-play is useful for generating large quantities of data for learning, but has the drawback that the agents the learner will face post-training may have dramatically different behavior than the learner came to expect by interacting with itself. For the special case of two-player constant-sum games, self-play that reaches Nash equilibrium is guaranteed to produce strategies that perform well against any post-training opponent; however, no such guarantee exists for multiplayer games. We show that in games that approximately decompose into a set of two-player constant-sum games (called constant-sum polymatrix games) where global $\epsilon$-Nash equilibria are boundedly far from Nash equilibria in each subgame (called subgame stability), any no-external-regret algorithm that learns by self-play will produce a strategy with bounded vulnerability. For the first time, our results identify a structural property of multiplayer games that enable performance guarantees for the strategies produced by a broad class of self-play algorithms. We demonstrate our findings through experiments on Leduc poker.


Finding emergence in data by maximizing effective information

arXiv.org Artificial Intelligence

Quantifying emergence and modeling emergent dynamics in a data-driven manner for complex dynamical systems is challenging due to the lack of direct observations at the micro-level. Thus, it's crucial to develop a framework to identify emergent phenomena and capture emergent dynamics at the macro-level using available data. Inspired by the theory of causal emergence (CE), this paper introduces a machine learning framework to learn macro-dynamics in an emergent latent space and quantify the degree of CE. The framework maximizes effective information, resulting in a macro-dynamics model with enhanced causal effects. Experimental results on simulated and real data demonstrate the effectiveness of the proposed framework. It quantifies degrees of CE effectively under various conditions and reveals distinct influences of different noise types. It can learn a one-dimensional coarse-grained macro-state from fMRI data, to represent complex neural activities during movie clip viewing. Furthermore, improved generalization to different test environments is observed across all simulation data.


An Efficient High-Dimensional Gene Selection Approach based on Binary Horse Herd Optimization Algorithm for Biological Data Classification

arXiv.org Artificial Intelligence

Abstract: The Horse Herd Optimization Algorithm (HOA) is a new meta-heuristic algorithm based on the behaviors of horses at different ages. The HOA was introduced recently to solve complex and high-dimensional problems. This paper proposes a binary version of the Horse Herd Optimization Algorithm (BHOA) in order to solve discrete problems and select prominent feature subsets. Moreover, this study provides a novel hybrid feature selection framework based on the BHOA and a minimum Redundancy Maximum Relevance (MRMR) filter method. This hybrid feature selection, which is more computationally efficient, produces a beneficial subset of relevant and informative features. Since feature selection is a binary problem, we have applied a new Transfer Function (TF), called X-shape TF, which transforms continuous problems into binary search spaces. Furthermore, the Support Vector Machine (SVM) is utilized to examine the efficiency of the proposed method on ten microarray datasets, namely Lymphoma, Prostate, Brain-1, DLBCL, SRBCT, Leukemia, Ovarian, Colon, Lung, and MLL. In comparison to other state-of-the-art, such as the Gray Wolf (GW), Particle Swarm Optimization (PSO), and Genetic Algorithm (GA), the proposed hybrid method (MRMR-BHOA) demonstrates superior performance in terms of accuracy and minimum selected features. Also, experimental results prove that the X-Shaped BHOA approach outperforms others methods. Introduction In recent years, many researchers have used DNA microarray datasets to analyze thousands of genes simultaneously and correlate their expression with clinical phenotypes in cancer research [1, 2]. Since the microarray dataset contains numerous redundant genes and a limited number of instances, the feature selection technique could be crucial for choosing informative genes [3]. Feature Selection (FS) should be applied in machine learning as a pre-processing phase in order to get optimal output with short training times and low memory consumption [4]. FS plays a significant role in data mining [5] to solve various problems such as data classification[6], data clustering [7], image processing [8], text clustering [9], disaster management [10], and disease forecasting [11]. FS is generally classified into three major groups based on a variety of evaluation criteria, i.e., filter method [12], wrapper model [13], and embedded technique [14]. Also, this technique uses statistical methods for the evaluation of a subset of features [15].


Operationalizing Counterfactual Metrics: Incentives, Ranking, and Information Asymmetry

arXiv.org Artificial Intelligence

From the social sciences to machine learning, it has been well documented that metrics to be optimized are not always aligned with social welfare. In healthcare, Dranove et al. (2003) showed that publishing surgery mortality metrics actually harmed the welfare of sicker patients by increasing provider selection behavior. We analyze the incentive misalignments that arise from such average treated outcome metrics, and show that the incentives driving treatment decisions would align with maximizing total patient welfare if the metrics (i) accounted for counterfactual untreated outcomes and (ii) considered total welfare instead of averaging over treated patients. Operationalizing this, we show how counterfactual metrics can be modified to behave reasonably in patient-facing ranking systems. Extending to realistic settings when providers observe more about patients than the regulatory agencies do, we bound the decay in performance by the degree of information asymmetry between principal and agent. In doing so, our model connects principal-agent information asymmetry with unobserved heterogeneity in causal inference.