Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be labor-intensive for researchers. To address this, we introduce CellAgent (http://cell.agent4science.cn/), an LLM-driven multi-agent framework, specifically designed for the automatic processing and execution of scRNA-seq data analysis tasks, providing high-quality results with no human intervention. Firstly, to adapt general LLMs to the biological field, CellAgent constructs LLM-driven biological expert roles - planner, executor, and evaluator - each with specific responsibilities. Then, CellAgent introduces a hierarchical decision-making mechanism to coordinate these biological experts, effectively driving the planning and step-by-step execution of complex data analysis tasks. Furthermore, we propose a self-iterative optimization mechanism, enabling CellAgent to autonomously evaluate and optimize solutions, thereby guaranteeing output quality. We evaluate CellAgent on a comprehensive benchmark dataset encompassing dozens of tissues and hundreds of distinct cell types. Evaluation results consistently show that CellAgent effectively identifies the most suitable tools and hyperparameters for single-cell analysis tasks, achieving optimal performance. This automated framework dramatically reduces the workload for science data analyses, bringing us into the "Agent for Science" era.

The ability of Language Models (LMs) to understand natural language makes them a powerful tool for parsing human instructions into task plans for autonomous robots. Unlike traditional planning methods that rely on domain-specific knowledge and handcrafted rules, LMs generalize from diverse data and adapt to various tasks with minimal tuning, acting as a compressed knowledge base. However, LMs in their standard form face challenges with long-horizon tasks, particularly in partially observable multi-agent settings. We propose an LM-based Long-Horizon Planner for Multi-Agent Robotics (LLaMAR), a cognitive architecture for planning that achieves state-of-the-art results in long-horizon tasks within partially observable environments. LLaMAR employs a plan-act-correct-verify framework, allowing self-correction from action execution feedback without relying on oracles or simulators. Additionally, we present MAP-THOR, a comprehensive test suite encompassing household tasks of varying complexity within the AI2-THOR environment. Experiments show that LLaMAR achieves a 30% higher success rate compared to other state-of-the-art LM-based multi-agent planners.

Recent advancements in Large Language Models (LLMs) have led to significant breakthroughs in various natural language processing tasks. However, generating factually consistent responses in knowledge-intensive scenarios remains a challenge due to issues such as hallucination, difficulty in acquiring long-tailed knowledge, and limited memory expansion. This paper introduces SMART, a novel multi-agent framework that leverages external knowledge to enhance the interpretability and factual consistency of LLM-generated responses. SMART comprises four specialized agents, each performing a specific sub-trajectory action to navigate complex knowledge-intensive tasks. We propose a multi-agent co-training paradigm, Long- and Short-Trajectory Learning, which ensures synergistic collaboration among agents while maintaining fine-grained execution by each agent. Extensive experiments on 5 tasks demonstrate SMART's superior performance compared to previous widely adopted methods.

This paper investigates the quality of multi-agent dialogues in simulations powered by Large Language Models (LLMs), focusing on a case study from Park et al. (2023), where 25 agents engage in day-long simulations of life, showcasing complex behaviors and interactions. Analyzing dialogues and memory over multiple sessions revealed significant issues such as repetition, inconsistency, and hallucination, exacerbated by the propagation of erroneous information. To combat these challenges, we propose a novel Screening, Diagnosis, and Regeneration (SDR) framework that detects and corrects utterance errors through a comprehensive process involving immediate issue identification, evidence gathering from past dialogues, and LLM analysis for utterance revision. The effectiveness of the SDR framework is validated through GPT-4 assessments and human evaluations, demonstrating marked improvements in dialogue consistency, diversity, and the reduction of false information. This work presents a pioneering approach to enhancing dialogue quality in multi-agent simulations, establishing a new standard for future research in the field.

We introduce the AutoGRAMS framework for programming multi-step interactions with language models. AutoGRAMS represents AI agents as a graph, where each node can execute either a language modeling instruction or traditional code. Likewise, transitions in the graph can be governed by either language modeling decisions or traditional branch logic. AutoGRAMS supports using variables as memory and allows nodes to call other AutoGRAMS graphs as functions. We show how AutoGRAMS can be used to design highly sophisticated agents, including self-referential agents that can modify their own graph. AutoGRAMS's graph-centric approach aids interpretability, controllability, and safety during the design, development, and deployment of AI agents. We provide our framework as open source at https://github.com/autograms/autograms .

Multi-agent systems (MAS) constitute a significant role in exploring machine intelligence and advanced applications. In order to deeply investigate complicated interactions within MAS scenarios, we originally propose "GNN for MBRL" model, which utilizes a state-spaced Graph Neural Networks with Model-based Reinforcement Learning to address specific MAS missions (e.g., Billiard-Avoidance, Autonomous Driving Cars). In detail, we firstly used GNN model to predict future states and trajectories of multiple agents, then applied the Cross-Entropy Method (CEM) optimized Model Predictive Control to assist the ego-agent planning actions and successfully accomplish certain MAS tasks.

An elusive goal in navigation research is to build an intelligent agent that can understand multimodal instructions including natural language and image, and perform useful navigation. To achieve this, we study a widely useful category of navigation tasks we call Multimodal Instruction Navigation with demonstration Tours (MINT), in which the environment prior is provided through a previously recorded demonstration video. Recent advances in Vision Language Models (VLMs) have shown a promising path in achieving this goal as it demonstrates capabilities in perceiving and reasoning about multimodal inputs. However, VLMs are typically trained to predict textual output and it is an open research question about how to best utilize them in navigation. To solve MINT, we present Mobility VLA, a hierarchical Vision-Language-Action (VLA) navigation policy that combines the environment understanding and common sense reasoning power of long-context VLMs and a robust low-level navigation policy based on topological graphs. The high-level policy consists of a long-context VLM that takes the demonstration tour video and the multimodal user instruction as input to find the goal frame in the tour video. Next, a low-level policy uses the goal frame and an offline constructed topological graph to generate robot actions at every timestep. We evaluated Mobility VLA in a 836m^2 real world environment and show that Mobility VLA has a high end-to-end success rates on previously unsolved multimodal instructions such as "Where should I return this?" while holding a plastic bin. A video demonstrating Mobility VLA can be found here: https://youtu.be/-Tof__Q8_5s

We present ACME: A Chatbot for asylum-seeking Migrants tool that goes beyond the checklists used for handling well-defined, in Europe. ACME relies on computational argumentation and simple procedures since there is not only a problem of evaluating aims to help migrants identify the highest level of protection they legal and factual data, but there is also an issue with understanding can apply for. This would contribute to a more sustainable migration which procedures are relevant. Indeed, there is not only one type of by reducing the load on territorial commissions, Courts, and humanitarian protection but several ones. Importantly, since applicants may be political organizations supporting asylum applicants. We describe the refugees and victims of abuse, discrimination, and persecution, context, system architectures, technologies, and the case study used the collection and processing of their personal data for immigration to run the demonstration.

Multi-Agent Path Finding (MAPF) aims to arrange collision-free goal-reaching paths for a group of agents. Anytime MAPF solvers based on large neighborhood search (LNS) have gained prominence recently due to their flexibility and scalability. Neighborhood selection strategy is crucial to the success of MAPF-LNS and a flurry of methods have been proposed. However, several pitfalls exist and hinder a comprehensive evaluation of these new methods, which mainly include: 1) Lower than actual or incorrect baseline performance; 2) Lack of a unified evaluation setting and criterion; 3) Lack of a codebase or executable model for supervised learning methods. To overcome these challenges, we conduct a fair comparison across prominent methods on the same benchmark and hyperparameter search settings. Additionally, we propose a simple neighborhood selection strategy which marks a clear advancement in terms of runtime efficiency in large maps with large number of agents. Our benchmarking evaluation promotes new challenges for existing learning based methods and presents opportunities for future research when machine learning is integrated with MAPF-LNS.

In this study, we address the issue of enabling an artificial intelligence agent to execute complex language instructions within virtual environments. In our framework, we assume that these instructions involve intricate linguistic structures and multiple interdependent tasks that must be navigated successfully to achieve the desired outcomes. To effectively manage these complexities, we propose a hierarchical framework that combines the deep language comprehension of large language models with the adaptive action-execution capabilities of reinforcement learning agents. The language module (based on LLM) translates the language instruction into a high-level action plan, which is then executed by a pre-trained reinforcement learning agent. We have demonstrated the effectiveness of our approach in two different environments: in IGLU, where agents are instructed to build structures, and in Crafter, where agents perform tasks and interact with objects in the surrounding environment according to language commands.