The COVID-19 pandemic brings many unexpected disruptions, such as frequently shifting markets and limited human workforce, to manufacturers. To stay competitive, flexible and real-time manufacturing decision-making strategies are needed to deal with such highly dynamic manufacturing environments. One essential problem is dynamic resource allocation to complete production tasks, especially when a resource disruption (e.g., machine breakdown) occurs. Though multi-agent methods have been proposed to solve the problem in a flexible and agile manner, the agent internal decision-making process and resource uncertainties have rarely been studied. This work introduces a model-based resource agent (RA) architecture that enables effective agent coordination and dynamic agent decision-making. Based on the RA architecture, a rescheduling strategy that incorporates risk assessment via a clustering agent coordination strategy is also proposed. A simulation-based case study is implemented to demonstrate dynamic rescheduling using the proposed multi-agent framework. The results show that the proposed method reduces the computational efforts while losing some throughput optimality compared to the centralized method. Furthermore, the case study illustrates that incorporating risk assessment into rescheduling decision-making improves the throughput.

-- Efficient exploration in multi-agent reinforcement learning (MARL) is a challenging problem when receiving only a team reward, especially in environments with sparse rewards. A powerful method to mitigate this issue involves crafting dense individual rewards to guide the agents toward efficient exploration. However, individual rewards generally rely on manually engineered shaping-reward functions that lack high-order intelligence, thus it behaves ineffectively than humans regarding learning and generalization in complex problems. T o tackle these issues, we combine the above two paradigms and propose a novel framework, LIGHT (Learning Individual Intrinsic reward via Incorporating Generalized Human experTise), which can integrate human knowledge into MARL algorithms in an end-to-end manner . LIGHT guides each agent to avoid unnecessary exploration by considering both individual action distribution and human expertise preference distribution. Then, LIGHT designs individual intrinsic rewards for each agent based on actionable representational transformation relevant to Q-learning so that the agents align their action preferences with the human expertise while maximizing the joint action value. Experimental results demonstrate the superiority of our method over representative baselines regarding performance and better knowledge reusability across different sparse-reward tasks on challenging scenarios. Cooperative multi-agent reinforcement learning (MARL) is an important branch in the field of artificial intelligence (AI), playing a crucial role in sequential challenging decision-making problems, such as in autonomous driving [1], sensor networks [2], [3] and robotics control [4]. Centralized training with decentralized execution (CTDE) paradigm has gained substantial attention in cooperative MARL that aims to facilitate agent cooperation by providing global state information during training and executing only based on local observations during execution [5], [6], [7].

--Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce an Agentic AI framework that automates the entire clinical data pipeline, from ingestion to inference, through a system of modular, task-specific agents. These agents are capable of handling both structured and unstructured data, enabling automatic feature selection, model selection, and preprocessing recommendation without manual intervention. We evaluate the system on publicly available datasets from geriatrics, palliative care, and colonoscopy imaging. For example, in the case of structured data (anxiety data) and unstructured data (colonoscopy polyps data), the pipeline begins with file-type detection by the "Ingestion Identifier Agent", followed by the "Data Anonymizer Agent" ensuring privacy compliance, where we first identify what type of data it is and then anonymize it. The "Feature Extraction Agent" then identifies features using an embedding-based approach for tabular data, which gives us all the column names, and a multistage MedGemma-based approach for image data, which gives us the modality and disease name. The "Preprocessing Recommender Agent" and "Preprocessing Implementor Agent" then apply tailored pre-processing based on data type and model requirements. Finally, the "Model Inference Agent" runs the selected model on the user uploaded data and generates interpretable outputs using tools like SHAP, LIME, and DETR attention maps. By automating these high-friction stages of the ML lifecycle, the proposed framework reduces the need for repeated expert intervention, offering a scalable and cost-efficient pathway for operationalizing AI in clinical environments. The integration of Artificial Intelligence (AI) into clinical workflows holds transformative potential for healthcare, enabling timely, data-driven decision-making across diagnosis and treatment planning [1].

Due to practical constraints such as partial observability and limited communication, Centralized Training with Decentralized Execution (CTDE) has become the dominant paradigm in cooperative Multi-Agent Reinforcement Learning (MARL). However, existing CTDE methods often underutilize centralized training or lack theoretical guarantees. We propose Multi-Agent Guided Policy Optimization (MAGPO), a novel framework that better leverages centralized training by integrating centralized guidance with decentralized execution. MAGPO uses an auto-regressive joint policy for scalable, coordinated exploration and explicitly aligns it with decentralized policies to ensure deployability under partial observability. We provide theoretical guarantees of monotonic policy improvement and empirically evaluate MAGPO on 43 tasks across 6 diverse environments. Results show that MAGPO consistently outperforms strong CTDE baselines and matches or surpasses fully centralized approaches, offering a principled and practical solution for decentralized multi-agent learning. Our code and experimental data can be found in https://github.com/liyheng/MAGPO.

As large language models (LLMs) are increasingly deployed as autonomous agents, understanding their cooperation and social mechanisms is becoming increasingly important. In particular, how LLMs balance self-interest and collective well-being is a critical challenge for ensuring alignment, robustness, and safe deployment. In this paper, we examine the challenge of costly sanctioning in multi-agent LLM systems, where an agent must decide whether to invest its own resources to incentivize cooperation or penalize defection. To study this, we adapt a public goods game with institutional choice from behavioral economics, allowing us to observe how different LLMs navigate social dilemmas over repeated interactions. Our analysis reveals four distinct behavioral patterns among models: some consistently establish and sustain high levels of cooperation, others fluctuate between engagement and disengagement, some gradually decline in cooperative behavior over time, and others rigidly follow fixed strategies regardless of outcomes. Surprisingly, we find that reasoning LLMs, such as the o1 series, struggle significantly with cooperation, whereas some traditional LLMs consistently achieve high levels of cooperation. These findings suggest that the current approach to improving LLMs, which focuses on enhancing their reasoning capabilities, does not necessarily lead to cooperation, providing valuable insights for deploying LLM agents in environments that require sustained collaboration. Our code is available at https://github.com/davidguzmanp/SanctSim

Large Language Model (LLM) based multi-agent systems have shown remarkable performance in various tasks, especially when enhanced through collaborative communication. However, current methods often rely on a fixed number of agents and static communication structures, limiting their ability to adapt to varying task complexities. In this paper, we propose Adaptive Graph Pruning (AGP), a novel task-adaptive multi-agent collaboration framework that jointly optimizes agent quantity (hard-pruning) and communication topology (soft-pruning). Specifically, our method employs a two-stage training strategy: firstly, independently training soft-pruning networks for different agent quantities to determine optimal agent-quantity-specific complete graphs and positional masks across specific tasks; and then jointly optimizing hard-pruning and soft-pruning within a maximum complete graph to dynamically configure the number of agents and their communication topologies per task. Extensive experiments demonstrate that our approach is: (1) High-performing, achieving state-of-the-art results across six benchmarks and consistently generalizes across multiple mainstream LLM architectures, with a increase in performance of $2.58\%\sim 9.84\%$; (2) Task-adaptive, dynamically constructing optimized communication topologies tailored to specific tasks, with an extremely high performance in all three task categories (general reasoning, mathematical reasoning, and code generation); (3) Token-economical, having fewer training steps and token consumption at the same time, with a decrease in token consumption of $90\%+$; and (4) Training-efficient, achieving high performance with very few training steps compared with other methods. The performance will surpass the existing baselines after about ten steps of training under six benchmarks.

Multi-Agent Pathfinding (MAPF) is the problem of finding paths for a set of agents such that each agent reaches its desired destination while avoiding collisions with the other agents. Many MAPF solvers are designed to run offline, that is, first generate paths for all agents and then execute them. Real-Time MAPF (RT-MAPF) embodies a realistic MAPF setup in which one cannot wait until a complete path for each agent has been found before they start to move. Instead, planning and execution are interleaved, where the agents must commit to a fixed number of steps in a constant amount of computation time, referred to as the planning budget. Existing solutions to RT-MAPF iteratively call windowed versions of MAPF algorithms in every planning period, without explicitly considering the size of the planning budget. We address this gap and explore different policies for allocating the planning budget in windowed versions of standard MAPF algorithms, namely Prioritized Planning (PrP) and MAPF-LNS2. Our exploration shows that the baseline approach in which all agents draw from a shared planning budget pool is ineffective in over-constrained situations. Instead, policies that distribute the planning budget over the agents are able to solve more problems with a smaller makespan.

Traffic Signal Control (TSC) is essential for managing urban traffic flow and reducing congestion. Reinforcement Learning (RL) offers an adaptive method for TSC by responding to dynamic traffic patterns, with multi-agent RL (MARL) gaining traction as intersections naturally function as coordinated agents. However, due to shifts in environmental dynamics, implementing MARL-based TSC policies in the real world often leads to a significant performance drop, known as the sim-to-real gap. Grounded Action Transformation (GAT) has successfully mitigated this gap in single-agent RL for TSC, but real-world traffic networks, which involve numerous interacting intersections, are better suited to a MARL framework. In this work, we introduce JL-GAT, an application of GAT to MARL-based TSC that balances scalability with enhanced grounding capability by incorporating information from neighboring agents. JL-GAT adopts a decentralized approach to GAT, allowing for the scalability often required in real-world traffic networks while still capturing key interactions between agents. Comprehensive experiments on various road networks under simulated adverse weather conditions, along with ablation studies, demonstrate the effectiveness of JL-GAT. The code is publicly available at https://github.com/DaRL-LibSignal/JL-GAT/.

Multi-agent systems (MASs) consisting of a number of autonomous agents that communicate, coordinate, and jointly sense the environment to achieve complex missions can be found in a variety of applications such as robotics, smart cities, and internet-of-things applications. Modeling and monitoring MAS requirements to guarantee overall mission objectives, safety, and reliability is an important problem. Such requirements implicitly require reasoning about diverse sensing and communication modalities between agents, analysis of the dependencies between agent tasks, and the spatial or virtual distance between agents. To capture such rich MAS requirements, we model agent interactions via multiple directed graphs, and introduce a new logic -- Spatio-Temporal Logic with Graph Operators (STL-GO). The key innovation in STL-GO are graph operators that enable us to reason about the number of agents along either the incoming or outgoing edges of the underlying interaction graph that satisfy a given property of interest; for example, the requirement that an agent should sense at least two neighboring agents whose task graphs indicate the ability to collaborate. We then propose novel distributed monitoring conditions for individual agents that use only local information to determine whether or not an STL-GO specification is satisfied. We compare the expressivity of STL-GO against existing spatio-temporal logic formalisms, and demonstrate the utility of STL-GO and our distributed monitors in a bike-sharing and a multi-drone case study.

Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through natural language, they often underperform compared to task-specific models. Collaborative multi-agent systems have emerged as a promising solution to balance versatility and accuracy in healthcare, yet their potential remains underexplored in pathology-specific domains. To address these issues, we propose WSI-Agents, a novel collaborative multi-agent system for multi-modal WSI analysis. WSI-Agents integrates specialized functional agents with robust task allocation and verification mechanisms to enhance both task-specific accuracy and multi-task versatility through three components: (1) a task allocation module assigning tasks to expert agents using a model zoo of patch and WSI level MLLMs, (2) a verification mechanism ensuring accuracy through internal consistency checks and external validation using pathology knowledge bases and domain-specific models, and (3) a summary module synthesizing the final summary with visual interpretation maps. Extensive experiments on multi-modal WSI benchmarks show WSI-Agents's superiority to current WSI MLLMs and medical agent frameworks across diverse tasks.