Large Language Model
MAGMA-Edu: Multi-Agent Generative Multimodal Framework for Text-Diagram Educational Question Generation
Wu, Zhenyu, Li, Jian, Huang, Hua
Educational illustrations play a central role in communicating abstract concepts, yet current multimodal large language models (MLLMs) remain limited in producing pedagogically coherent and semantically consistent educational visuals. We introduce MAGMA-Edu, a self-reflective multi-agent framework that unifies textual reasoning and diagrammatic synthesis for structured educational problem generation. Unlike existing methods that treat text and image generation independently, MAGMA-Edu employs a two-stage co-evolutionary pipeline: (1) a generation-verification-reflection loop that iteratively refines question statements and solutions for mathematical accuracy, and (2) a code-based intermediate representation that enforces geometric fidelity and semantic alignment during image rendering. Both stages are guided by internal self-reflection modules that evaluate and revise outputs until domain-specific pedagogical constraints are met. Extensive experiments on multimodal educational benchmarks demonstrate the superiority of MAGMA-Edu over state-of-the-art MLLMs. Compared to GPT-4o, MAGMA-Edu improves the average textual metric from 57.01 to 92.31 (+35.3 pp) and boosts image-text consistency (ITC) from 13.20 to 85.24 (+72 pp). Across all model backbones, MAGMA-Edu achieves the highest scores (Avg-Text 96.20, ITC 99.12), establishing a new state of the art for multimodal educational content generation and demonstrating the effectiveness of self-reflective multi-agent collaboration in pedagogically aligned vision-language reasoning.
Empathetic Cascading Networks: A Multi-Stage Prompting Technique for Reducing Social Biases in Large Language Models
This report presents the Empathetic Cascading Networks (ECN) framework, a multi-stage prompting method designed to enhance the empathetic and inclusive capabilities of large language models. ECN employs four stages: Perspective Adoption, Emotional Resonance, Reflective Understanding, and Integrative Synthesis, to guide models toward generating emotionally resonant and contextually aware responses. Experimental results demonstrate that ECN achieves the highest Empathy Quotient (EQ) scores across GPT-3.5-turbo and GPT-4, while maintaining competitive Regard and Perplexity metrics. These findings emphasize ECN's potential for applications requiring empathy and inclusivity in conversational AI.
VLM in a flash: I/O-Efficient Sparsification of Vision-Language Model via Neuron Chunking
Yang, Kichang, Kim, Seonjun, Kim, Minjae, Zhang, Nairan, Zhang, Chi, Lee, Youngki
Edge deployment of large Vision-Language Models (VLMs) increasingly relies on flash-based weight offloading, where activation sparsification is used to reduce I/O overhead. However, conventional sparsification remains model-centric, selecting neurons solely by activation magnitude and neglecting how access patterns influence flash performance. We present Neuron Chunking, an I/O-efficient sparsification strategy that operates on chunks (i.e., groups of contiguous neurons in memory) and couples neuron importance with storage access cost. The method models I/O latency through a lightweight abstraction of access contiguity and selects chunks with high utility, defined as neuron importance normalized by estimated latency. By aligning sparsification decisions with the underlying storage behavior, Neuron Chunking improves I/O efficiency by up to 4.65x and 5.76x on Jetson Orin Nano and Jetson AGX Orin, respectively.
MedVision: Dataset and Benchmark for Quantitative Medical Image Analysis
Yao, Yongcheng, Zong, Yongshuo, Dutt, Raman, Yang, Yongxin, Tsaftaris, Sotirios A, Hospedales, Timothy
Current vision-language models (VLMs) in medicine are primarily designed for categorical question answering (e.g., "Is this normal or abnormal?") or qualitative descriptive tasks. However, clinical decision-making often relies on quantitative assessments, such as measuring the size of a tumor or the angle of a joint, from which physicians draw their own diagnostic conclusions. This quantitative reasoning capability remains underexplored and poorly supported in existing VLMs. In this work, we introduce MedVision, a large-scale dataset and benchmark specifically designed to evaluate and improve VLMs on quantitative medical image analysis. MedVision spans 22 public datasets covering diverse anatomies and modalities, with 30.8 million image-annotation pairs. We focus on three representative quantitative tasks: (1) detection of anatomical structures and abnormalities, (2) tumor/lesion (T/L) size estimation, and (3) angle/distance (A/D) measurement. Our benchmarks show that current off-the-shelf VLMs perform poorly on these tasks. However, with supervised fine-tuning on MedVision, we significantly enhance their performance across detection, T/L estimation, and A/D measurement, demonstrating reduced error rates and improved precision. This work provides a foundation for developing VLMs with robust quantitative reasoning capabilities in medical imaging. Code and data are available at https://medvision-vlm.github.io.
Kitty: Accurate and Efficient 2-bit KV Cache Quantization with Dynamic Channel-wise Precision Boost
Xia, Haojun, Wu, Xiaoxia, Li, Jisen, Wu, Robert, Wang, Junxiong, Wang, Jue, Li, Chenxi, Singhal, Aman, Shah, Alay Dilipbhai, Ariyak, Alpay, Zhuang, Donglin, Zhou, Zhongzhu, Athiwaratkun, Ben, Zheng, Zhen, Song, Shuaiwen Leon
The KV cache is a dominant memory bottleneck for LLM inference. While 4-bit KV quantization preserves accuracy, 2-bit often degrades it, especially on long-context reasoning. We close this gap via an algorithm-system co-design for mixed-precision KV caching: Kitty. On the algorithm side, extensive experiments show that Dynamic Channel-wise Precision Boost -- which ranks Key-cache channels by sensitivity and keeps only a small fraction at higher precision -- maintains near-zero loss in accuracy drop while approaching 2-bit memory. The main challenge is handling dynamic 4-bit channel boosts while keeping the page layout coalesced and the dequantization uniform, with no scattered reads or hard-coded masks. Kitty addresses these issues by decompose each mixed-precision Key page into two tensors with unified 2-bit precision. Based on this, Kitty provides a page-centric KV layout, Triton-compatible page dequantization kernels, and a lightweight runtime pipeline that preserves coalescing and avoids divergence. Across seven tasks and two model families (Qwen3, LLaMA3), Kitty cuts KV memory by nearly 8x with negligible accuracy loss, enabling up to 8x larger batches and 2.1x-4.1x higher throughput under the same memory budget. We release the full implementation of Kitty at https://github.com/Summer-Summer/Kitty.
Health system learning achieves generalist neuroimaging models
Kondepudi, Akhil, Rao, Akshay, Zhao, Chenhui, Lyu, Yiwei, Harake, Samir, Banerjee, Soumyanil, Joshi, Rushikesh, Meissner, Anna-Katharina, Hou, Renly, Jiang, Cheng, Chowdury, Asadur, Srinivasan, Ashok, Athey, Brian, Gulani, Vikas, Pandey, Aditya, Lee, Honglak, Hollon, Todd
Frontier artificial intelligence (AI) models, such as OpenAI's GPT-5 and Meta's DINOv3, have advanced rapidly through training on internet-scale public data, yet such systems lack access to private clinical data. Neuroimaging, in particular, is underrepresented in the public domain due to identifiable facial features within MRI and CT scans, fundamentally restricting model performance in clinical medicine. Here, we show that frontier models underperform on neuroimaging tasks and that learning directly from uncurated data generated during routine clinical care at health systems, a paradigm we call health system learning, yields high-performance, generalist neuroimaging models. We introduce NeuroVFM, a visual foundation model trained on 5.24 million clinical MRI and CT volumes using a scalable volumetric joint-embedding predictive architecture. NeuroVFM learns comprehensive representations of brain anatomy and pathology, achieving state-of-the-art performance across multiple clinical tasks, including radiologic diagnosis and report generation. The model exhibits emergent neuroanatomic understanding and interpretable visual grounding of diagnostic findings. When paired with open-source language models through lightweight visual instruction tuning, NeuroVFM generates radiology reports that surpass frontier models in accuracy, clinical triage, and expert preference. Through clinically grounded visual understanding, NeuroVFM reduces hallucinated findings and critical errors, offering safer clinical decision support. These results establish health system learning as a paradigm for building generalist medical AI and provide a scalable framework for clinical foundation models.
No Free Lunch in Language Model Bias Mitigation? Targeted Bias Reduction Can Exacerbate Unmitigated LLM Biases
Chand, Shireen, Baca, Faith, Ferrara, Emilio
Large Language Models (LLMs) inherit societal biases from their training data, potentially leading to harmful or unfair outputs. While various techniques aim to mitigate these biases, their effects are often evaluated only along the dimension of the bias being targeted. This work investigates the cross-category consequences of targeted bias mitigation. We study four bias mitigation techniques applied across ten models from seven model families, and we explore racial, religious, profession- and gender-related biases. We measure the impact of debiasing on model coherence and stereotypical preference using the StereoSet benchmark. Our results consistently show that while targeted mitigation can sometimes reduce bias in the intended dimension, it frequently leads to unintended and often negative consequences in others, such as increasing model bias and decreasing general coherence. These findings underscore the critical need for robust, multi-dimensional evaluation tools when examining and developing bias mitigation strategies to avoid inadvertently shifting or worsening bias along untargeted axes.
The Locally Deployable Virtual Doctor: LLM Based Human Interface for Automated Anamnesis and Database Conversion
Ruhland, Jan Benedikt, Bahcivan, Doguhan, Sowa, Jan-Peter, Canbay, Ali, Heider, Dominik
Recent advances in large language models made it possible to achieve high conversational performance with substantially reduced computational demands, enabling practical on-site deployment in clinical environments. Such progress allows for local integration of AI systems that uphold strict data protection and patient privacy requirements, yet their secure implementation in medicine necessitates careful consideration of ethical, regulatory, and technical constraints. In this study, we introduce MedChat, a locally deployable virtual physician framework that integrates an LLM-based medical chatbot with a diffusion-driven avatar for automated and structured anamnesis. The chatbot was fine-tuned using a hybrid corpus of real and synthetically generated medical dialogues, while model efficiency was optimized via Low-Rank Adaptation. A secure and isolated database interface was implemented to ensure complete separation between patient data and the inference process. The avatar component was realized through a conditional diffusion model operating in latent space, trained on researcher video datasets and synchronized with mel-frequency audio features for realistic speech and facial animation. Unlike existing cloud-based systems, this work demonstrates the feasibility of a fully offline, locally deployable LLM-diffusion framework for clinical anamnesis. The autoencoder and diffusion networks exhibited smooth convergence, and MedChat achieved stable fine-tuning with strong generalization to unseen data. The proposed system thus provides a privacy-preserving, resource-efficient foundation for AI-assisted clinical anamnesis, also in low-cost settings.
Toward Trustworthy Difficulty Assessments: Large Language Models as Judges in Programming and Synthetic Tasks
Tabib, H. M. Shadman, Deedar, Jaber Ahmed
Large Language Models (LLMs) have demonstrated impressive capabilities in natural language and code generation, and are increasingly deployed as automatic judges of model outputs and learning activities. Yet, their behavior on structured tasks such as predicting the difficulty of competitive programming problems remains under-explored. We conduct a systematic comparison of GPT-4o, used purely as a natural-language difficulty assessor, against an interpretable Light-GBM ensemble trained on explicit numeric and textual features. On a dataset of 1,825 LeetCode problems labeled Easy, Medium, or Hard, LightGBM attains 86% accuracy, whereas GPT-4o reaches only 37.75%. Detailed analyses, including confusion matrices and SHAP-based interpretability, show that numeric constraints -- such as input size limits and acceptance rates -- play a crucial role in separating Hard problems from easier ones. By contrast, GPT-4o often overlooks these cues and exhibits a strong bias toward simpler categories. We further probe GPT-4o through a synthetic Hard-problem generation protocol. Surprisingly, GPT-4o labels almost all of its own synthetic Hard problems as Medium, contradicting its tendency to downgrade real Hard problems to Easy. Our findings connect to recent work on LLMs-as-judges and automatic difficulty estimation in programming and education, and highlight concrete failure modes that must be addressed before LLM-based judges can be considered trustworthy in competitive programming, educational platforms, or reinforcement-learning pipelines.
Strategic Decision Framework for Enterprise LLM Adoption
Trusov, Michael, Hwang, Minha, Jamal, Zainab, Chandra, Swarup
Organizations are rapidly adopting Large Language Models (LLMs) to transform their operations, yet they lack clear guidance on key decisions for adoption and implementation. While LLMs offer powerful capabilities in content generation, assisted coding, and process automation, businesses face critical challenges in data security, LLM solution development approach, infrastructure requirements, and deployment strategies. Healthcare providers must protect patient data while leveraging LLMs for medical analysis, financial institutions need to balance automated customer service with regulatory compliance, and software companies seek to enhance development productivity while maintaining code security. This article presents a systematic six-step decision framework for LLM adoption, helping organizations navigate from initial application selection to final deployment. Based on extensive interviews and analysis of successful and failed implementations, our framework provides practical guidance for business leaders to align technological capabilities with business objectives. Through key decision points and real-world examples from both B2B and B2C contexts, organizations can make informed decisions about LLM adoption while ensuring secure and efficient integration across various use cases, from customer service automation to content creation and advanced analytics.