With the rapid advancement of Large Language Models (LLMs) and their outstanding performance in semantic and contextual comprehension, the potential of LLMs in specialized domains warrants exploration. This paper introduces the NoteAid EHR Interaction Pipeline, an innovative approach developed using generative LLMs to assist in patient education, a task stemming from the need to aid patients in understanding Electronic Health Records (EHRs). Building upon the NoteAid work, we designed two novel tasks from the patient's perspective: providing explanations for EHR content that patients may not understand and answering questions posed by patients after reading their EHRs. We extracted datasets containing 10,000 instances from MIMIC Discharge Summaries and 876 instances from the MADE medical notes collection, respectively, executing the two tasks through the NoteAid EHR Interaction Pipeline with these data. Performance data of LLMs on these tasks were collected and constructed as the corresponding NoteAid EHR Interaction Dataset. Through a comprehensive evaluation of the entire dataset using LLM assessment and a rigorous manual evaluation of 64 instances, we showcase the potential of LLMs in patient education. Besides, the results provide valuable data support for future exploration and applications in this domain while also supplying high-quality synthetic datasets for in-house system training.

Through large language models (LLMs) have marked a engaging in interactive dialogues, each agent participates transformative shift across numerous domains in instructive and responsive conversations, (Vaswani et al., 2017; Brown et al., 2020; Bubeck collaboratively contributing to the achievement et al., 2023). Despite their impressive abilities, of a cohesive and automated solution for task when dealing with complex situations that extend completion. The development of a more adaptive beyond mere chatting, these models show certain and proactive approach to problem-solving by limitations inherent in their standalone capabilities these agents marks a significant leap in autonomy, (Richards, 2023). Recent research in autonomous going beyond the typical prompt-guided dynamic agents has significantly advanced LLMs in human-computer interactions (Yang et al., by integrating sophisticated features like contextsensitive 2023a) and substantially reducing dependence on memory (Park et al., 2023), multi-step human involvement (Li et al., 2023a; Qian et al., planning (Wei et al., 2022b), and strategic use of external 2023; Wu et al., 2023).

Large Language Models (LLMs) have revolutionized various domains with extensive knowledge and creative capabilities. However, a critical issue with LLMs is their tendency to produce outputs that diverge from factual reality. This phenomenon is particularly concerning in sensitive applications such as medical consultation and legal advice, where accuracy is paramount. In this paper, we introduce the LLM factoscope, a novel Siamese network-based model that leverages the inner states of LLMs for factual detection. Our investigation reveals distinguishable patterns in LLMs' inner states when generating factual versus non-factual content. We demonstrate the LLM factoscope's effectiveness across various architectures, achieving over 96% accuracy in factual detection. Our work opens a new avenue for utilizing LLMs' inner states for factual detection and encourages further exploration into LLMs' inner workings for enhanced reliability and transparency.

The Large Language Model Bias Index (LLMBI) is a pioneering approach designed to quantify and address biases inherent in large language models (LLMs), such as GPT-4. We recognise the increasing prevalence and impact of LLMs across diverse sectors. This research introduces a novel metric, LLMBI, to systematically measure and mitigate biases potentially skewing model responses. We formulated LLMBI using a composite scoring system incorporating multiple dimensions of bias, including but not limited to age, gender, and racial biases. To operationalise this metric, we engaged in a multi-step process involving collecting and annotating LLM responses, applying sophisticated Natural Language Processing (NLP) techniques for bias detection, and computing the LLMBI score through a specially crafted mathematical formula. The formula integrates weighted averages of various bias dimensions, a penalty for dataset diversity deficiencies, and a correction for sentiment biases. Our empirical analysis, conducted using responses from OpenAI's API, employs advanced sentiment analysis as a representative method for bias detection. The research reveals LLMs, whilst demonstrating impressive capabilities in text generation, exhibit varying degrees of bias across different dimensions. LLMBI provides a quantifiable measure to compare biases across models and over time, offering a vital tool for systems engineers, researchers and regulators in enhancing the fairness and reliability of LLMs. It highlights the potential of LLMs in mimicking unbiased human-like responses. Additionally, it underscores the necessity of continuously monitoring and recalibrating such models to align with evolving societal norms and ethical standards.

Knowledge graph construction (KGC) is a multifaceted undertaking involving the extraction of entities, relations, and events. Traditionally, large language models (LLMs) have been viewed as solitary task-solving agents in this complex landscape. However, this paper challenges this paradigm by introducing a novel framework, CooperKGC. Departing from the conventional approach, CooperKGC establishes a collaborative processing network, assembling a KGC collaboration team capable of concurrently addressing entity, relation, and event extraction tasks. Our experiments unequivocally demonstrate that fostering collaboration and information interaction among diverse agents within CooperKGC yields superior results compared to individual cognitive processes operating in isolation. Importantly, our findings reveal that the collaboration facilitated by CooperKGC enhances knowledge selection, correction, and aggregation capabilities across multiple rounds of interactions.

Autonomous driving technology, a catalyst for revolutionizing transportation and urban mobility, has the tend to transition from rule-based systems to data-driven strategies. Traditional module-based systems are constrained by cumulative errors among cascaded modules and inflexible pre-set rules. In contrast, end-to-end autonomous driving systems have the potential to avoid error accumulation due to their fully data-driven training process, although they often lack transparency due to their "black box" nature, complicating the validation and traceability of decisions. Recently, large language models (LLMs) have demonstrated abilities including understanding context, logical reasoning, and generating answers. A natural thought is to utilize these abilities to empower autonomous driving. By combining LLM with foundation vision models, it could open the door to open-world understanding, reasoning, and few-shot learning, which current autonomous driving systems are lacking. In this paper, we systematically review a research line about \textit{Large Language Models for Autonomous Driving (LLM4AD)}. This study evaluates the current state of technological advancements, distinctly outlining the principal challenges and prospective directions for the field. For the convenience of researchers in academia and industry, we provide real-time updates on the latest advances in the field as well as relevant open-source resources via the designated link: https://github.com/Thinklab-SJTU/Awesome-LLM4AD.

Comprehensive and accurate evaluation of general-purpose AI systems such as large language models allows for effective mitigation of their risks and deepened understanding of their capabilities. Current evaluation methodology, mostly based on benchmarks of specific tasks, falls short of adequately assessing these versatile AI systems, as present techniques lack a scientific foundation for predicting their performance on unforeseen tasks and explaining their varying performance on specific task items or user inputs. Moreover, existing benchmarks of specific tasks raise growing concerns about their reliability and validity. To tackle these challenges, we suggest transitioning from task-oriented evaluation to construct-oriented evaluation. Psychometrics, the science of psychological measurement, provides a rigorous methodology for identifying and measuring the latent constructs that underlie performance across multiple tasks. We discuss its merits, warn against potential pitfalls, and propose a framework to put it into practice. Finally, we explore future opportunities of integrating psychometrics with the evaluation of general-purpose AI systems.

We introduce NoteChat, a novel cooperative multi-agent framework leveraging Large Language Models (LLMs) to generate patient-physician dialogues. NoteChat embodies the principle that an ensemble of role-specific LLMs, through structured role-play and strategic prompting, can perform their assigned roles more effectively. The synergy among these role-playing LLMs results in a cohesive and efficient dialogue generation. Evaluation on MTS-dialogue, a benchmark dataset for patient-physician dialogues-note pairs, shows that models trained with the augmented synthetic patient-physician dialogues by NoteChat outperforms other state-of-the-art models for generating clinical notes. Our comprehensive automatic and human evaluation demonstrates that NoteChat substantially surpasses state-of-the-art models like ChatGPT and GPT-4 up to 22.78% by domain experts in generating superior synthetic patient-physician dialogues based on clinical notes. NoteChat has the potential to engage patients directly and help clinical documentation, a leading cause of physician burnout.

Modern generative models exhibit unprecedented capabilities to generate extremely realistic data. However, given the inherent compositionality of the real world, reliable use of these models in practical applications requires that they exhibit the capability to compose a novel set of concepts to generate outputs not seen in the training data set. Prior work demonstrates that recent diffusion models do exhibit intriguing compositional generalization abilities, but also fail unpredictably. Motivated by this, we perform a controlled study for understanding compositional generalization in conditional diffusion models in a synthetic setting, varying different attributes of the training data and measuring the model's ability to generate samples out-of-distribution. Our results show: (i) the order in which the ability to generate samples from a concept and compose them emerges is governed by the structure of the underlying data-generating process; (ii) performance on compositional tasks exhibits a sudden "emergence" due to multiplicative reliance on the performance of constituent tasks, partially explaining emergent phenomena seen in generative models; and (iii) composing concepts with lower frequency in the training data to generate out-of-distribution samples requires considerably more optimization steps compared to generating in-distribution samples. Overall, our study lays a foundation for understanding emergent capabilities and compositionality in generative models from a data-centric perspective.

Large Language Models (LLMs) show powerful capabilities in natural language understanding by capturing hidden semantics in vector space. However, the direct transmission of text to servers poses a largely unaddressed risk of privacy leakage. To mitigate this issue, we introduce Split-N-Denoise (SnD), an innovative framework that splits the model to execute the token embedding layer on the client side at minimal computational cost. This allows the client to introduce noise prior to transmitting the embeddings to the server, and subsequently receive and denoise the perturbed output embeddings for downstream tasks. Our approach is designed for the inference stage of LLMs and requires no modifications to the model parameters. Extensive experiments demonstrate SnD's effectiveness in optimizing the privacy-utility tradeoff across various LLM architectures and diverse downstream tasks. The results reveal an improvement in performance under the same privacy budget compared to the baselines by over 10% on average, offering clients a privacy-preserving solution for local privacy protection. Large Language Models (LLMs) have shown powerful capability in natural language understanding by capturing hidden semantics in vector space. Consequently, users can leverage LLMs to obtain embeddings and subsequently apply them to their own downstream tasks, known as "embedding as a service" (EaaS). However, EaaS is typically provided as an online service, giving rise to significant privacy concerns. In particular, users may input sensitive information, such as names, phones, and email addresses, that needs to be kept hidden from the service provider.