Given the societal impact of unsafe content generated by large language models (LLMs), ensuring that LLM services comply with safety standards is a crucial concern for LLM service providers. Common content moderation methods are limited by an effectiveness-and-efficiency dilemma, where simple models are fragile while sophisticated models consume excessive computational resources. In this paper, we reveal for the first time that effective and efficient content moderation can be achieved by extracting conceptual features from chat-oriented LLMs, despite their initial fine-tuning for conversation rather than content moderation. We propose a practical and unified content moderation framework for LLM services, named Legilimens, which features both effectiveness and efficiency. Our red-team model-based data augmentation enhances the robustness of Legilimens against state-of-the-art jailbreaking. Additionally, we develop a framework to theoretically analyze the cost-effectiveness of Legilimens compared to other methods. We have conducted extensive experiments on five host LLMs, seventeen datasets, and nine jailbreaking methods to verify the effectiveness, efficiency, and robustness of Legilimens against normal and adaptive adversaries. A comparison of Legilimens with both commercial and academic baselines demonstrates the superior performance of Legilimens. Furthermore, we confirm that Legilimens can be applied to few-shot scenarios and extended to multi-label classification tasks.

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing clinical trial processes. This review highlights the expanding role of LLMs in revolutionizing various stages of the drug development pipeline. We investigate how these advanced computational models can uncover target-disease linkage, interpret complex biomedical data, enhance drug molecule design, predict drug efficacy and safety profiles, and facilitate clinical trial processes. Our paper aims to provide a comprehensive overview for researchers and practitioners in computational biology, pharmacology, and AI4Science by offering insights into the potential transformative impact of LLMs on drug discovery and development.

Large-scale visuomotor policy learning is a promising approach toward developing generalizable manipulation systems. Yet, policies that can be deployed on diverse embodiments, environments, and observational modalities remain elusive. In this work, we investigate how knowledge from large-scale visual data of the world may be used to address one axis of variation for generalizable manipulation: observational viewpoint. Specifically, we study single-image novel view synthesis models, which learn 3D-aware scene-level priors by rendering images of the same scene from alternate camera viewpoints given a single input image. For practical application to diverse robotic data, these models must operate zero-shot, performing view synthesis on unseen tasks and environments. We empirically analyze view synthesis models within a simple data-augmentation scheme that we call View Synthesis Augmentation (VISTA) to understand their capabilities for learning viewpoint-invariant policies from single-viewpoint demonstration data. Upon evaluating the robustness of policies trained with our method to out-of-distribution camera viewpoints, we find that they outperform baselines in both simulated and real-world manipulation tasks. Videos and additional visualizations are available at https://s-tian.github.io/projects/vista.

Large language models (LLMs) have shown remarkable capabilities in generating user summaries from a long list of raw user activity data. These summaries capture essential user information such as preferences and interests, and therefore are invaluable for LLM-based personalization applications, such as explainable recommender systems. However, the development of new summarization techniques is hindered by the lack of ground-truth labels, the inherent subjectivity of user summaries, and human evaluation which is often costly and time-consuming. To address these challenges, we introduce \UserSumBench, a benchmark framework designed to facilitate iterative development of LLM-based summarization approaches. This framework offers two key components: (1) A reference-free summary quality metric. We show that this metric is effective and aligned with human preferences across three diverse datasets (MovieLens, Yelp and Amazon Review). (2) A novel robust summarization method that leverages time-hierarchical summarizer and self-critique verifier to produce high-quality summaries while eliminating hallucination. This method serves as a strong baseline for further innovation in summarization techniques.

This paper introduces MetaBGM, a groundbreaking framework for generating background music that adapts to dynamic scenes and real-time user interactions. We define multi-scene as variations in environmental contexts, such as transitions in game settings or movie scenes. To tackle the challenge of converting backend data into music description texts for audio generation models, MetaBGM employs a novel two-stage generation approach that transforms continuous scene and user state data into these texts, which are then fed into an audio generation model for real-time soundtrack creation. Experimental results demonstrate that MetaBGM effectively generates contextually relevant and dynamic background music for interactive applications.

Although Large Language Models (LLMs) have demonstrated potential in processing graphs, they struggle with comprehending graphical structure information through prompts of graph description sequences, especially as the graph size increases. We attribute this challenge to the uneven memory performance of LLMs across different positions in graph description sequences, known as "positional biases". To address this, we propose GraphInsight, a novel framework aimed at improving LLMs' comprehension of both macro-and micro-level graphical information. GraphInsight is grounded in two key strategies: 1) placing critical graphical information in positions where LLMs exhibit stronger memory performance, and 2) investigating a lightweight external knowledge base for regions with weaker memory performance, inspired by retrieval-augmented generation (RAG). Moreover, GraphInsight explores integrating these two strategies into LLM agent processes for composite graph tasks that require multi-step reasoning. Extensive empirical studies on benchmarks with a wide range of evaluation tasks show that GraphInsight significantly outperforms all other graph description methods (e.g., prompting techniques and reordering strategies) in understanding graph structures of varying sizes. Among these domains, leveraging LLMs to tackle applications involving graphs has emerged as a burgeoning field of research, as graphs represent fundamental structures that capture intricate relationships and interactions in the real world Wang et al. (2021); Xu (2021). For example, Fatemi et al. have explored the potential of LLMs by converting various types of graphs, such as knowledge graphs Baek et al. (2023); Pan et al. (2024) and social network graphs Santra (2024); Babic (2023), into natural language descriptions, thereby enabling LLMs to perform question-answering tasks related to these graphs. A key observation is that enhancing LLM performance in graph-related applications depends critically on LLMs' ability to comprehend graph structures through natural language descriptions. Existing studies Shang & Huang (2024); Li et al. (2023) primarily utilizes two direct methods to transform graphs into text inputs for LLMs: the structural format transforming, such as adjacency matrices (termed as AM) or lists (termed as AL) and the sequential format transforming, such as edge-by-edge These authors contributed equally to this work. However, extensive empirical studies Yuan et al. (2024) have shown that LLMs face significant challenges in understanding and reasoning about graph structures using current graph transformation methods, especially as graph size increases, leading to a "comprehension collapse". As shown in Figure 1 (a), several common LLMs perform poorly on graph structure understanding tasks (see benchmarks in Section 5.1), and their comprehension declines sharply as the graph size increases, ultimately leading to complete failure.

With the emergence of widely available powerful LLMs, disinformation generated by large Language Models (LLMs) has become a major concern. Historically, LLM detectors have been touted as a solution, but their effectiveness in the real world is still to be proven. In this paper, we focus on an important setting in information operations -- short news-like posts generated by moderately sophisticated attackers. We demonstrate that existing LLM detectors, whether zero-shot or purpose-trained, are not ready for real-world use in that setting. All tested zero-shot detectors perform inconsistently with prior benchmarks and are highly vulnerable to sampling temperature increase, a trivial attack absent from recent benchmarks. A purpose-trained detector generalizing across LLMs and unseen attacks can be developed, but it fails to generalize to new human-written texts. We argue that the former indicates domain-specific benchmarking is needed, while the latter suggests a trade-off between the adversarial evasion resilience and overfitting to the reference human text, with both needing evaluation in benchmarks and currently absent. We believe this suggests a re-consideration of current LLM detector benchmarking approaches and provides a dynamically extensible benchmark to allow it (https://github.com/Reliable-Information-Lab-HEVS/dynamic_llm_detector_benchmark).

This paper investigates the RWKV model's efficacy in content moderation through targeted experimentation. We introduce a novel dataset specifically designed for distillation into smaller models, enhancing content moderation practices. This comprehensive dataset encompasses images, videos, sounds, and text data that present societal challenges. Leveraging advanced Large Language Models (LLMs), we generated an extensive set of responses -- 558,958 for text and 83,625 for images -- to train and refine content moderation systems. Our core experimentation involved fine-tuning the RWKV model, capitalizing on its CPU-efficient architecture to address large-scale content moderation tasks. By highlighting the dataset's potential for knowledge distillation, this study not only demonstrates RWKV's capability in improving the accuracy and efficiency of content moderation systems but also paves the way for developing more compact, resource-efficient models in this domain. Datasets and models can be found in HuggingFace: https://huggingface.co/modrwkv

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering, MedS-Bench spans 11 high-level clinical tasks, including clinical report summarization, treatment recommendations, diagnosis, named entity recognition, and medical concept explanation, among others. We evaluated six leading LLMs, e.g., MEDITRON, Mistral, InternLM 2, Llama 3, GPT-4, and Claude-3.5 using few-shot prompting, and found that even the most sophisticated models struggle with these complex tasks. To address these limitations, we developed MedS-Ins, a large-scale instruction tuning dataset for medicine. MedS-Ins comprises 58 medically oriented language corpora, totaling 13.5 million samples across 122 tasks. To demonstrate the dataset's utility, we conducted a proof-of-concept experiment by performing instruction tuning on a lightweight, open-source medical language model. The resulting model, MMedIns-Llama 3, significantly outperformed existing models across nearly all clinical tasks. To promote further advancements in the application of LLMs to clinical challenges, we have made the MedS-Ins dataset fully accessible and invite the research community to contribute to its expansion.Additionally, we have launched a dynamic leaderboard for MedS-Bench, which we plan to regularly update the test set to track progress and enhance the adaptation of general LLMs to the medical domain. Leaderboard: https://henrychur.github.io/MedS-Bench/. Github: https://github.com/MAGIC-AI4Med/MedS-Ins.

Large language models (LLMs) represented by GPT family have achieved remarkable success. The characteristics of LLMs lie in their ability to accommodate a wide range of tasks through a generative approach. However, the flexibility of their output format poses challenges in controlling and harnessing the model's outputs, thereby constraining the application of LLMs in various domains. In this work, we present Sketch, an innovative toolkit designed to streamline LLM operations across diverse fields. Sketch comprises the following components: (1) a suite of task description schemas and prompt templates encompassing various NLP tasks; (2) a user-friendly, interactive process for building structured output LLM services tailored to various NLP tasks; (3) an open-source dataset for output format control, along with tools for dataset construction; and (4) an open-source model based on LLaMA3-8B-Instruct that adeptly comprehends and adheres to output formatting instructions. We anticipate this initiative to bring considerable convenience to LLM users, achieving the goal of ''plug-and-play'' for various applications. The components of Sketch will be progressively open-sourced at https://github.com/cofe-ai/Sketch.