We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical data, this system aims to support healthcare professionals in delivering better patient outcomes and informed decision-making. Through innovative use of BERT and BioBERT models, combined with a multi-layer perceptron (MLP) layer, we enable more specialized and efficient responses to the growing demands of the healthcare sector. Our approach not only addresses the challenge of overfitting by freezing one BERT model while training another but also improves the overall adaptability of QA services. The use of extensive datasets, such as BioASQ and BioMRC, demonstrates the system's ability to synthesize critical information. This work highlights how advanced language models can make a tangible difference in healthcare, providing reliable and responsive tools for professionals to manage complex information, ultimately serving the broader goal of improved care and data-driven insights.

This research explores a hybrid approach to fine-tuning large language models (LLMs) by integrating real-world and synthetic data to boost model performance, particularly in generating accurate and contextually relevant responses. By leveraging a dataset combining transcribed real interactions with high-quality synthetic sessions, we aimed to overcome the limitations of scarce, noisy, and domain-specific real data. Synthetic personas and scenarios were employed to enhance training diversity. The study evaluated three models: a base foundational model, a model fine-tuned with real data, and a hybrid fine-tuned model. Experimental results showed that the hybrid model consistently outperformed the others in specific vertical applications, achieving the highest scores across all metrics. Further testing confirmed the hybrid model's superior adaptability and contextual understanding across diverse scenarios. These findings suggest that combining real and synthetic data can significantly improve the robustness and contextual sensitivity of LLMs, particularly in domain-specific and vertical use cases.

Classifier-Free Guidance (CFG) is a critical technique for enhancing the sample quality of visual generative models. However, in autoregressive (AR) multi-modal generation, CFG introduces design inconsistencies between language and visual content, contradicting the design philosophy of unifying different modalities for visual AR. Motivated by language model alignment methods, we propose \textit{Condition Contrastive Alignment} (CCA) to facilitate guidance-free AR visual generation with high performance and analyze its theoretical connection with guided sampling methods. Unlike guidance methods that alter the sampling process to achieve the ideal sampling distribution, CCA directly fine-tunes pretrained models to fit the same distribution target. Experimental results show that CCA can significantly enhance the guidance-free performance of all tested models with just one epoch of fine-tuning ($\sim$ 1\% of pretraining epochs) on the pretraining dataset, on par with guided sampling methods. This largely removes the need for guided sampling in AR visual generation and cuts the sampling cost by half. Moreover, by adjusting training parameters, CCA can achieve trade-offs between sample diversity and fidelity similar to CFG. This experimentally confirms the strong theoretical connection between language-targeted alignment and visual-targeted guidance methods, unifying two previously independent research fields. Code and model weights: https://github.com/thu-ml/CCA.

Sparse reward environments in reinforcement learning (RL) pose significant challenges for exploration, often leading to inefficient or incomplete learning processes. To tackle this issue, this work proposes a teacher-student RL framework that leverages Large Language Models (LLMs) as "teachers" to guide the agent's learning process by decomposing complex tasks into subgoals. Due to their inherent capability to understand RL environments based on a textual description of structure and purpose, LLMs can provide subgoals to accomplish the task defined for the environment in a similar fashion to how a human would do. In doing so, three types of subgoals are proposed: positional targets relative to the agent, object representations, and language-based instructions generated directly by the LLM. More importantly, we show that it is possible to query the LLM only during the training phase, enabling agents to operate within the environment without any LLM intervention. We assess the performance of this proposed framework by evaluating three state-of-the-art open-source LLMs (Llama, DeepSeek, Qwen) eliciting subgoals across various procedurally generated environment of the MiniGrid benchmark. Experimental results demonstrate that this curriculum-based approach accelerates learning and enhances exploration in complex tasks, achieving up to 30 to 200 times faster convergence in training steps compared to recent baselines designed for sparse reward environments.

In high-stakes domains like legal question-answering, the accuracy and trustworthiness of generative AI systems are of paramount importance. This work presents a comprehensive benchmark of various methods to assess the groundedness of AI-generated responses, aiming to significantly enhance their reliability. Our experiments include similarity-based metrics and natural language inference models to evaluate whether responses are well-founded in the given contexts. We also explore different prompting strategies for large language models to improve the detection of ungrounded responses. We validated the effectiveness of these methods using a newly created grounding classification corpus, designed specifically for legal queries and corresponding responses from retrieval-augmented prompting, focusing on their alignment with source material. Our results indicate potential in groundedness classification of generated responses, with the best method achieving a macro-F1 score of 0.8. Additionally, we evaluated the methods in terms of their latency to determine their suitability for real-world applications, as this step typically follows the generation process. This capability is essential for processes that may trigger additional manual verification or automated response regeneration. In summary, this study demonstrates the potential of various detection methods to improve the trustworthiness of generative AI in legal settings.

Learning from Demonstrations, particularly from biological experts like humans and animals, often encounters significant data acquisition challenges. While recent approaches leverage internet videos for learning, they require complex, task-specific pipelines to extract and retarget motion data for the agent. In this work, we introduce a language-model-assisted bi-level programming framework that enables a reinforcement learning agent to directly learn its reward from internet videos, bypassing dedicated data preparation. The framework includes two levels: an upper level where a vision-language model (VLM) provides feedback by comparing the learner's behavior with expert videos, and a lower level where a large language model (LLM) translates this feedback into reward updates. The VLM and LLM collaborate within this bi-level framework, using a "chain rule" approach to derive a valid search direction for reward learning. We validate the method for reward learning from YouTube videos, and the results have shown that the proposed method enables efficient reward design from expert videos of biological agents for complex behavior synthesis.

Federated Learning (FL) is a machine learning technique that enables multiple entities to collaboratively learn a shared model without exchanging their local data. Over the past decade, FL systems have achieved substantial progress, scaling to millions of devices across various learning domains while offering meaningful differential privacy (DP) guarantees. Production systems from organizations like Google, Apple, and Meta demonstrate the real-world applicability of FL. However, key challenges remain, including verifying server-side DP guarantees and coordinating training across heterogeneous devices, limiting broader adoption. Additionally, emerging trends such as large (multi-modal) models and blurred lines between training, inference, and personalization challenge traditional FL frameworks. In response, we propose a redefined FL framework that prioritizes privacy principles rather than rigid definitions. We also chart a path forward by leveraging trusted execution environments and open-source ecosystems to address these challenges and facilitate future advancements in FL.

Audio descriptions (ADs) function as acoustic commentaries designed to assist blind persons and persons with visual impairments in accessing digital media content on television and in movies, among other settings. As an accessibility service typically provided by trained AD professionals, the generation of ADs demands significant human effort, making the process both time-consuming and costly. Recent advancements in natural language processing (NLP) and computer vision (CV), particularly in large language models (LLMs) and vision-language models (VLMs), have allowed for getting a step closer to automatic AD generation. This paper reviews the technologies pertinent to AD generation in the era of LLMs and VLMs: we discuss how state-of-the-art NLP and CV technologies can be applied to generate ADs and identify essential research directions for the future.

The safety alignment ability of Vision-Language Models (VLMs) is prone to be degraded by the integration of the vision module compared to its LLM backbone. We investigate this phenomenon, dubbed as ''safety alignment degradation'' in this paper, and show that the challenge arises from the representation gap that emerges when introducing vision modality to VLMs. In particular, we show that the representations of multi-modal inputs shift away from that of text-only inputs which represent the distribution that the LLM backbone is optimized for. At the same time, the safety alignment capabilities, initially developed within the textual embedding space, do not successfully transfer to this new multi-modal representation space. To reduce safety alignment degradation, we introduce Cross-Modality Representation Manipulation (CMRM), an inference time representation intervention method for recovering the safety alignment ability that is inherent in the LLM backbone of VLMs, while simultaneously preserving the functional capabilities of VLMs. The empirical results show that our framework significantly recovers the alignment ability that is inherited from the LLM backbone with minimal impact on the fluency and linguistic capabilities of pre-trained VLMs even without additional training. Specifically, the unsafe rate of LLaVA-7B on multi-modal input can be reduced from 61.53% to as low as 3.15% with only inference-time intervention. WARNING: This paper contains examples of toxic or harmful language.

Large Language Models (LLMs) are gaining significant popularity in recent years for specialized tasks using prompts due to their low computational cost. Standard methods like prefix tuning utilize special, modifiable tokens that lack semantic meaning and require extensive training for best performance, often falling short. In this context, we propose a novel method called Semantic Knowledge Tuning (SK-Tuning) for prompt and prefix tuning that employs meaningful words instead of random tokens. This method involves using a fixed LLM to understand and process the semantic content of the prompt through zero-shot capabilities. Following this, it integrates the processed prompt with the input text to improve the model's performance on particular tasks. Our experimental results show that SK-Tuning exhibits faster training times, fewer parameters, and superior performance on tasks such as text classification and understanding compared to other tuning methods. This approach offers a promising method for optimizing the efficiency and effectiveness of LLMs in processing language tasks.