This white paper, developed through close collaboration between IBM Research and UIUC researchers within the IIDAI Institute, envisions transforming hybrid cloud systems to meet the growing complexity of AI workloads through innovative, full-stack co-design approaches, emphasizing usability, manageability, affordability, adaptability, efficiency, and scalability. By integrating cutting-edge technologies such as generative and agentic AI, cross-layer automation and optimization, unified control plane, and composable and adaptive system architecture, the proposed framework addresses critical challenges in energy efficiency, performance, and cost-effectiveness. Incorporating quantum computing as it matures will enable quantum-accelerated simulations for materials science, climate modeling, and other high-impact domains. Collaborative efforts between academia and industry are central to this vision, driving advancements in foundation models for material design and climate solutions, scalable multimodal data processing, and enhanced physics-based AI emulators for applications like weather forecasting and carbon sequestration. Research priorities include advancing AI agentic systems, LLM as an Abstraction (LLMaaA), AI model optimization and unified abstractions across heterogeneous infrastructure, end-to-end edge-cloud transformation, efficient programming model, middleware and platform, secure infrastructure, application-adaptive cloud systems, and new quantum-classical collaborative workflows. These ideas and solutions encompass both theoretical and practical research questions, requiring coordinated input and support from the research community. This joint initiative aims to establish hybrid clouds as secure, efficient, and sustainable platforms, fostering breakthroughs in AI-driven applications and scientific discovery across academia, industry, and society.

With the increasing impacts of climate change, there is a growing demand for accessible tools that can provide reliable future climate information to support planning, finance, and other decision-making applications. Large language models (LLMs), such as GPT-4, present a promising approach to bridging the gap between complex climate data and the general public, offering a way for non-specialist users to obtain essential climate insights through natural language interaction. However, an essential challenge remains under-explored: evaluating the ability of LLMs to provide accurate and reliable future climate predictions, which is crucial for applications that rely on anticipating climate trends. In this study, we investigate the capability of GPT-4 in predicting rainfall at short-term (15-day) and long-term (12-month) scales. We designed a series of experiments to assess GPT's performance under different conditions, including scenarios with and without expert data inputs. Our results indicate that GPT, when operating independently, tends to generate conservative forecasts, often reverting to historical averages in the absence of clear trend signals. This study highlights both the potential and challenges of applying LLMs for future climate predictions, providing insights into their integration with climate-related applications and suggesting directions for enhancing their predictive capabilities in the field.

The disparity in access to quality education is significant, both between developed and developing countries and within nations, regardless of their economic status. Socioeconomic barriers and rapid changes in the job market further intensify this issue, highlighting the need for innovative solutions that can deliver quality education at scale and low cost. This paper addresses these challenges by proposing an AI-powered digital learning framework grounded in Deep Learning (DL) theory. The DL theory emphasizes learner agency and redefines the role of teachers as facilitators, making it particularly suitable for scalable educational environments. We outline eight key principles derived from learning science and AI that are essential for implementing DL-based Digital Learning Environments (DLEs). Our proposed framework leverages AI for learner modelling based on Open Learner Modeling (OLM), activity suggestions, and AI-assisted support for both learners and facilitators, fostering collaborative and engaging learning experiences. Our framework provides a promising direction for scalable, high-quality education globally, offering practical solutions to some of the AI-related challenges in education.

This paper presents the latest version of the Global AI Vibrancy Tool (GVT), an interactive suite of visualizations designed to facilitate the comparison of AI vibrancy across 36 countries, using 42 indicators organized into 8 pillars. The tool offers customizable features that allow users to conduct in-depth country-level comparisons and longitudinal analyses of AI-related metrics, all based on publicly available data. By providing a transparent assessment of national progress in AI, it serves the diverse needs of policymakers, industry leaders, researchers, and the general public. Using weights for indicators and pillars developed by AI Index's panel of experts and combined into an index, the Global AI Vibrancy Ranking for 2023 places the United States first by a significant margin, followed by China and the United Kingdom. The ranking also highlights the rise of smaller nations such as Singapore when evaluated on both absolute and per capita bases. The tool offers three sub-indices for evaluating Global AI Vibrancy along different dimensions: the Innovation Index, the Economic Competitiveness Index, and the Policy, Governance, and Public Engagement Index.

With the rapid development of large language models (LLM), robots are starting to enjoy the benefits of new interaction methods that large language models bring. Because edge computing fulfills the needs for rapid response, privacy, and network autonomy, we believe it facilitates the extensive deployment of large models for robot navigation across various industries. To enable local deployment of language models on edge devices, we adopt some model boosting methods. In this paper, we propose FASTNav - a method for boosting lightweight LLMs, also known as small language models (SLMs), for robot navigation. The proposed method contains three modules: fine-tuning, teacher-student iteration, and language-based multi-point robot navigation. We train and evaluate models with FASTNav in both simulation and real robots, proving that we can deploy them with low cost, high accuracy and low response time. Compared to other model compression methods, FASTNav shows potential in the local deployment of language models and tends to be a promising solution for language-guided robot navigation on edge devices.

Large Language Models (LLMs) have become increasingly popular for generating RTL code. However, producing error-free RTL code in a zero-shot setting remains highly challenging for even state-of-the-art LLMs, often leading to issues that require manual, iterative refinement. This additional debugging process can dramatically increase the verification workload, underscoring the need for robust, automated correction mechanisms to ensure code correctness from the start. In this work, we introduce AIvril2, a self-verifying, LLM-agnostic agentic framework aimed at enhancing RTL code generation through iterative corrections of both syntax and functional errors. Our approach leverages a collaborative multi-agent system that incorporates feedback from error logs generated by EDA tools to automatically identify and resolve design flaws. Experimental results, conducted on the VerilogEval-Human benchmark suite, demonstrate that our framework significantly improves code quality, achieving nearly a 3.4$\times$ enhancement over prior methods. In the best-case scenario, functional pass rates of 77% for Verilog and 66% for VHDL were obtained, thus substantially improving the reliability of LLM-driven RTL code generation.

Large Language Models based on transformer algorithms have revolutionized Artificial Intelligence by enabling verbal interaction with machines akin to human conversation. These AI agents have surpassed the Turing Test, achieving confusion rates up to 50%. However, challenges persist, especially with the advent of robots and the need to humanize machines for improved Human-AI collaboration. In this experiment, three GPT agents with varying levels of agreeableness (disagreeable, neutral, agreeable) based on the Big Five Inventory were tested in a Turing Test. All exceeded a 50% confusion rate, with the highly agreeable AI agent surpassing 60%. This agent was also recognized as exhibiting the most human-like traits. Various explanations in the literature address why these GPT agents were perceived as human, including psychological frameworks for understanding anthropomorphism. These findings highlight the importance of personality engineering as an emerging discipline in artificial intelligence, calling for collaboration with psychology to develop ergonomic psychological models that enhance system adaptability in collaborative activities.

Antibodies safeguard our health through their precise and potent binding to specific antigens, demonstrating promising therapeutic efficacy in the treatment of numerous diseases, including COVID-19. Recent advancements in biomedical language models have shown the great potential to interpret complex biological structures and functions. However, existing antibody specific models have a notable limitation that they lack explicit consideration for antibody structural information, despite the fact that both 1D sequence and 3D structure carry unique and complementary insights into antibody behavior and functionality. This paper proposes Sequence-Structure multi-level pre-trained Antibody Language Model (S$^2$ALM), combining holistic sequential and structural information in one unified, generic antibody foundation model. We construct a hierarchical pre-training paradigm incorporated with two customized multi-level training objectives to facilitate the modeling of comprehensive antibody representations. S$^2$ALM's representation space uncovers inherent functional binding mechanisms, biological evolution properties and structural interaction patterns. Pre-trained over 75 million sequences and 11.7 million structures, S$^2$ALM can be adopted for diverse downstream tasks: accurately predicting antigen-antibody binding affinities, precisely distinguishing B cell maturation stages, identifying antibody crucial binding positions, and specifically designing novel coronavirus-binding antibodies. Remarkably, S$^2$ALM outperforms well-established and renowned baselines and sets new state-of-the-art performance across extensive antibody specific understanding and generation tasks. S$^2$ALM's ability to model comprehensive and generalized representations further positions its potential to advance real-world therapeutic antibody development, potentially addressing unmet academic, industrial, and clinical needs.

We designed a Retrieval-Augmented Generation (RAG) system to provide large language models with relevant documents for answering domain-specific questions about Pittsburgh and Carnegie Mellon University (CMU). We extracted over 1,800 subpages using a greedy scraping strategy and employed a hybrid annotation process, combining manual and Mistral-generated question-answer pairs, achieving an inter-annotator agreement (IAA) score of 0.7625. Our RAG framework integrates BM25 and FAISS retrievers, enhanced with a reranker for improved document retrieval accuracy. Experimental results show that the RAG system significantly outperforms a non-RAG baseline, particularly in time-sensitive and complex queries, with an F1 score improvement from 5.45% to 42.21% and recall of 56.18%. This study demonstrates the potential of RAG systems in enhancing answer precision and relevance, while identifying areas for further optimization in document retrieval and model training.

This study investigates gender bias in large language models (LLMs) by comparing their gender perception to that of human respondents, U.S. Bureau of Labor Statistics data, and a 50% no-bias benchmark. We created a new evaluation set using occupational data and role-specific sentences. Unlike common benchmarks included in LLM training data, our set is newly developed, preventing data leakage and test set contamination. Five LLMs were tested to predict the gender for each role using single-word answers. We used Kullback-Leibler (KL) divergence to compare model outputs with human perceptions, statistical data, and the 50% neutrality benchmark. All LLMs showed significant deviation from gender neutrality and aligned more with statistical data, still reflecting inherent biases.