Artificial Intelligence is revolutionizing medical practice, enhancing diagnostic accuracy and healthcare delivery. However, its adaptation in medical settings still faces significant challenges, related to data availability and privacy constraints. Synthetic data has emerged as a promising solution to mitigate these issues, addressing data scarcity while preserving privacy. Recently, Latent Diffusion Models have emerged as a powerful tool for generating high-quality synthetic data. Meanwhile, the integration of different modalities has gained interest, emphasizing the need of models capable of handle multimodal medical data. Existing approaches struggle to integrate complementary information and lack the ability to generate modalities simultaneously. To address this challenge, we present MedCoDi-M, a 6.77-billion-parameter model, designed for multimodal medical data generation, that, following Foundation Model paradigm, exploits contrastive learning and large quantity of data to build a shared latent space which capture the relationships between different data modalities. Further, we introduce the Multi-Prompt training technique, which significantly boosts MedCoDi-M's generation under different settings. We extensively validate MedCoDi-M: first we benchmark it against five competitors on the MIMIC-CXR dataset, a state-of-the-art dataset for Chest X-ray and radiological report generation. Secondly, we perform a Visual Turing Test with expert radiologists to assess the realism and clinical relevance of the generated data, ensuring alignment with real-world scenarios. Finally, we assess the utility of MedCoDi-M in addressing key challenges in the medical field, such as anonymization, data scarcity and imbalance learning. The results are promising, demonstrating the applicability of MedCoDi-M in medical contexts. Project page is at https://cosbidev.github.io/MedCoDi-M/.

Recent advancements in omnimodal learning have been achieved in understanding and generation across images, text, and speech, though mainly within proprietary models. Limited omnimodal datasets and the inherent challenges associated with real-time emotional speech generation have hindered open-source progress. To address these issues, we propose openomni, a two-stage training method combining omnimodal alignment and speech generation to develop a state-of-the-art omnimodal large language model. In the alignment phase, a pre-trained speech model is further trained on text-image tasks to generalize from vision to speech in a (near) zero-shot manner, outperforming models trained on tri-modal datasets. In the speech generation phase, a lightweight decoder facilitates real-time emotional speech through training on speech tasks and preference learning. Experiments demonstrate that openomni consistently improves across omnimodal, vision-language, and speech-language evaluations, enabling natural, emotion-rich dialogues and real-time emotional speech generation.

The rapid development of large language models (LLMs) and large vision models (LVMs) have propelled the evolution of multi-modal AI systems, which have demonstrated the remarkable potential for industrial applications by emulating human-like cognition. However, they also pose significant ethical challenges, including amplifying harmful content and reinforcing societal biases. For instance, biases in some industrial image generation models highlighted the urgent need for robust fairness assessments. Most existing evaluation frameworks focus on the comprehensiveness of various aspects of the models, but they exhibit critical limitations, including insufficient attention to content generation alignment and social bias-sensitive domains. More importantly, their reliance on pixel-detection techniques is prone to inaccuracies. To address these issues, this paper presents INFELM, an in-depth fairness evaluation on widely-used text-to-image models. Our key contributions are: (1) an advanced skintone classifier incorporating facial topology and refined skin pixel representation to enhance classification precision by at least 16.04%, (2) a bias-sensitive content alignment measurement for understanding societal impacts, (3) a generalizable representation bias evaluation for diverse demographic groups, and (4) extensive experiments analyzing large-scale text-to-image model outputs across six social-bias-sensitive domains. We find that existing models in the study generally do not meet the empirical fairness criteria, and representation bias is generally more pronounced than alignment errors. INFELM establishes a robust benchmark for fairness assessment, supporting the development of multi-modal AI systems that align with ethical and human-centric principles.

Large language models, despite extensive alignment with human values and ethical principles, remain vulnerable to sophisticated jailbreak attacks that exploit their reasoning abilities. Existing safety measures often detect overt malicious intent but fail to address subtle, reasoning-driven vulnerabilities. In this work, we introduce POATE (Polar Opposite query generation, Adversarial Template construction, and Elaboration), a novel jailbreak technique that harnesses contrastive reasoning to provoke unethical responses. POATE crafts semantically opposing intents and integrates them with adversarial templates, steering models toward harmful outputs with remarkable subtlety. We conduct extensive evaluation across six diverse language model families of varying parameter sizes to demonstrate the robustness of the attack, achieving significantly higher attack success rates (~44%) compared to existing methods. To counter this, we propose Intent-Aware CoT and Reverse Thinking CoT, which decompose queries to detect malicious intent and reason in reverse to evaluate and reject harmful responses. These methods enhance reasoning robustness and strengthen the model's defense against adversarial exploits.

We introduce REFA, a family of reference-free alignment methods that optimize over multiple user preferences while enforcing fine-grained length control. Our approach integrates deviation-based weighting to emphasize high-quality responses more strongly, length normalization to prevent trivial short-response solutions, and an EOS-probability regularizer to mitigate dataset-induced brevity biases. Theoretically, we show that under the Uncertainty Reduction with Sequence Length Assertion (URSLA), naive length normalization can still incentivize length-based shortcuts. By contrast, REFA corrects these subtle incentives, guiding models toward genuinely more informative and higher-quality outputs. Empirically, REFA sets a new state-of-the-art among reference-free alignment methods, producing richer responses aligned more closely with human preferences. Compared to a base supervised fine-tuned (SFT) mistral-7b model that achieves 8.4% length-controlled win rate (LC-WR) and 6.2% win rate (WR), our best REFA configuration attains 21.62% LC-WR and 19.87% WR on the AlpacaEval v2 benchmark. This represents a substantial improvement over both the strongest multi-preference baseline, InfoNCA (16.82% LC-WR, 10.44% WR), and the strongest reference-free baseline, SimPO (20.01% LC-WR, 17.65% WR)

Large language models (LLMs) are increasingly utilized in applications where system prompts, which guide model outputs, play a crucial role. These prompts often contain business logic and sensitive information, making their protection essential. However, adversarial and even regular user queries can exploit LLM vulnerabilities to expose these hidden prompts. To address this issue, we propose PromptKeeper, a robust defense mechanism designed to safeguard system prompts. PromptKeeper tackles two core challenges: reliably detecting prompt leakage and mitigating side-channel vulnerabilities when leakage occurs. By framing detection as a hypothesis-testing problem, PromptKeeper effectively identifies both explicit and subtle leakage. Upon detection, it regenerates responses using a dummy prompt, ensuring that outputs remain indistinguishable from typical interactions when no leakage is present. PromptKeeper ensures robust protection against prompt extraction attacks via either adversarial or regular queries, while preserving conversational capability and runtime efficiency during benign user interactions.

Reinforcement learning (RL) often encounters delayed and sparse feedback in real-world applications, even with only episodic rewards. Previous approaches have made some progress in reward redistribution for credit assignment but still face challenges, including training difficulties due to redundancy and ambiguous attributions stemming from overlooking the multifaceted nature of mission performance evaluation. Hopefully, Large Language Model (LLM) encompasses fruitful decision-making knowledge and provides a plausible tool for reward redistribution. Even so, deploying LLM in this case is non-trivial due to the misalignment between linguistic knowledge and the symbolic form requirement, together with inherent randomness and hallucinations in inference. To tackle these issues, we introduce LaRe, a novel LLM-empowered symbolic-based decision-making framework, to improve credit assignment. Key to LaRe is the concept of the Latent Reward, which works as a multi-dimensional performance evaluation, enabling more interpretable goal attainment from various perspectives and facilitating more effective reward redistribution. We examine that semantically generated code from LLM can bridge linguistic knowledge and symbolic latent rewards, as it is executable for symbolic objects. Meanwhile, we design latent reward self-verification to increase the stability and reliability of LLM inference. Theoretically, reward-irrelevant redundancy elimination in the latent reward benefits RL performance from more accurate reward estimation. Extensive experimental results witness that LaRe (i) achieves superior temporal credit assignment to SOTA methods, (ii) excels in allocating contributions among multiple agents, and (iii) outperforms policies trained with ground truth rewards for certain tasks.

Large Language Models (LLMs) present massive inherent knowledge and superior semantic comprehension capability, which have revolutionized various tasks in natural language processing. Despite their success, a critical gap remains in enabling LLMs to perform knowledge graph completion (KGC). Empirical evidence suggests that LLMs consistently perform worse than conventional KGC approaches, even through sophisticated prompt design or tailored instruction-tuning. Fundamentally, applying LLMs on KGC introduces several critical challenges, including a vast set of entity candidates, hallucination issue of LLMs, and under-exploitation of the graph structure. To address these challenges, we propose a novel instruction-tuning-based method, namely FtG. Specifically, we present a \textit{filter-then-generate} paradigm and formulate the KGC task into a multiple-choice question format. In this way, we can harness the capability of LLMs while mitigating the issue casused by hallucinations. Moreover, we devise a flexible ego-graph serialization prompt and employ a structure-text adapter to couple structure and text information in a contextualized manner. Experimental results demonstrate that FtG achieves substantial performance gain compared to existing state-of-the-art methods. The instruction dataset and code are available at \url{https://github.com/LB0828/FtG}.

The strong performance of large language models (LLMs) raises extensive discussion on their application to code generation. Recent research suggests continuous program refinements through visible tests to improve code generation accuracy in LLMs. However, these methods suffer from LLMs' inefficiency and limited reasoning capacity. In this work, we propose an LLM programming workflow (LPW) designed to improve both initial code generation and subsequent refinements within a structured two-phase workflow. Specifically, the solution generation phase formulates a solution plan, which is then verified through visible tests to specify the intended natural language solution. Subsequently, the code implementation phase drafts an initial code according to the solution plan and its verification. If the generated code fails the visible tests, the plan verification serves as the intended solution to consistently inform the refinement process for correcting bugs. Compared to state-of-the-art methods across various existing LLMs, LPW significantly improves the Pass@1 accuracy by up to 16.4% on well-established text-to-code generation benchmarks. LPW also sets new state-of-the-art Pass@1 accuracy, achieving 98.2% on HumanEval, 84.8% on MBPP, 59.3% on LiveCode, 62.6% on APPS, and 34.7% on CodeContest, using GPT-4o as the backbone.

Network pruning focuses on computational techniques that aim to reduce a given model's computational cost by removing a subset of its parameters while having minimal impact on performance. Throughout the last decade, the most widely used pruning paradigm has been pruning and re-training, which nowadays is inconvenient due to the vast amount of pre-trained models, which are in any case too expensive to re-train. In this paper, we exploit functional information from dense pre-trained models, i.e., their activations, to obtain sparse models that maximize the activations' alignment w.r.t. their corresponding dense models. Hence, we propose \textsc{NeuroAL}, a \emph{top-up} algorithm that can be used on top of any given pruning algorithm for LLMs, which modifies the block-wise and row-wise sparsity exploiting information from both the dense model and its sparse version to maximize the \emph{neuron alignment} among activations. Differently from existing methods, our approach adaptively selects the best hyperparameters for the block-wise and row-wise sparsity ratios w.r.t. the model and the desired sparsity, and requires \emph{no re-training}. We test our method over 276 cases combining four LLM families, three sparsity ratios, and ten language tasks (three language modeling and seven zero-shot datasets), showing how it consistently outperforms the latest state-of-the-art methods in terms of performance-runtime trade-off. The code is available at \href{https://github.com/eliacunegatti/NeuroAL}{https://github.com/eliacunegatti/NeuroAL}.