Large Language Model
LLMEval-Med: A Real-world Clinical Benchmark for Medical LLMs with Physician Validation
Zhang, Ming, Shen, Yujiong, Li, Zelin, Sha, Huayu, Hu, Binze, Wang, Yuhui, Huang, Chenhao, Liu, Shichun, Tong, Jingqi, Jiang, Changhao, Chai, Mingxu, Xi, Zhiheng, Dou, Shihan, Gui, Tao, Zhang, Qi, Huang, Xuanjing
Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and specialized assessments. However, these benchmarks have limitations in question design (mostly multiple-choice), data sources (often not derived from real clinical scenarios), and evaluation methods (poor assessment of complex reasoning). To address these issues, we present LLMEval-Med, a new benchmark covering five core medical areas, including 2,996 questions created from real-world electronic health records and expert-designed clinical scenarios. We also design an automated evaluation pipeline, incorporating expert-developed checklists into our LLM-as-Judge framework. Furthermore, our methodology validates machine scoring through human-machine agreement analysis, dynamically refining checklists and prompts based on expert feedback to ensure reliability. We evaluate 13 LLMs across three categories (specialized medical models, open-source models, and closed-source models) on LLMEval-Med, providing valuable insights for the safe and effective deployment of LLMs in medical domains. The dataset is released in https://github.com/llmeval/LLMEval-Med.
Auto prompt sql: a resource-efficient architecture for text-to-sql translation in constrained environments
Tang, Zetong, Ma, Qian, Wu, Di
Using the best Text-to-SQL methods in resource-constrained environments is challenging due to their reliance on resource-intensive open-source models. This paper introduces Auto Prompt SQL(AP-SQL), a novel architecture designed to bridge the gap between resource-efficient small open-source models and the powerful capabilities of large closed-source models for Text-to-SQL translation. Our method decomposes the task into schema filtering, retrieval-augmented text-to-SQL generation based on in-context examples, and prompt-driven schema linking and SQL generation. To improve schema selection accuracy, we fine-tune large language models. Crucially, we also explore the impact of prompt engineering throughout the process, leveraging Chain-of-Thought(CoT) and Graph-of-Thought(GoT) templates to significantly enhance the model's reasoning for accurate SQL generation. Comprehensive evaluations on the Spider benchmarks demonstrate the effectiveness of AP-SQL.
Multiple LLM Agents Debate for Equitable Cultural Alignment
Ki, Dayeon, Rudinger, Rachel, Zhou, Tianyi, Carpuat, Marine
Large Language Models (LLMs) need to adapt their predictions to diverse cultural contexts to benefit diverse communities across the world. While previous efforts have focused on single-LLM, single-turn approaches, we propose to exploit the complementary strengths of multiple LLMs to promote cultural adaptability. We introduce a Multi-Agent Debate framework, where two LLM-based agents debate over a cultural scenario and collaboratively reach a final decision. We propose two variants: one where either LLM agents exclusively debate and another where they dynamically choose between self-reflection and debate during their turns. We evaluate these approaches on 7 open-weight LLMs (and 21 LLM combinations) using the NormAd-ETI benchmark for social etiquette norms in 75 countries. Experiments show that debate improves both overall accuracy and cultural group parity over single-LLM baselines. Notably, multi-agent debate enables relatively small LLMs (7-9B) to achieve accuracies comparable to that of a much larger model (27B parameters).
PreGenie: An Agentic Framework for High-quality Visual Presentation Generation
Xu, Xiaojie, Xu, Xinli, Chen, Sirui, Chen, Haoyu, Zhang, Fan, Chen, Ying-Cong
Visual presentations are vital for effective communication. Early attempts to automate their creation using deep learning often faced issues such as poorly organized layouts, inaccurate text summarization, and a lack of image understanding, leading to mismatched visuals and text. These limitations restrict their application in formal contexts like business and scientific research. To address these challenges, we propose PreGenie, an agentic and modular framework powered by multimodal large language models (MLLMs) for generating high-quality visual presentations. PreGenie is built on the Slidev presentation framework, where slides are rendered from Markdown code. It operates in two stages: (1) Analysis and Initial Generation, which summarizes multimodal input and generates initial code, and (2) Review and Re-generation, which iteratively reviews intermediate code and rendered slides to produce final, high-quality presentations. Each stage leverages multiple MLLMs that collaborate and share information. Comprehensive experiments demonstrate that PreGenie excels in multimodal understanding, outperforming existing models in both aesthetics and content consistency, while aligning more closely with human design preferences.
Federated Retrieval-Augmented Generation: A Systematic Mapping Study
Chakraborty, Abhijit, Dahal, Chahana, Gupta, Vivek
Federated Retrieval-Augmented Generation (Federated RAG) combines Federated Learning (FL), which enables distributed model training without exposing raw data, with Retrieval-Augmented Generation (RAG), which improves the factual accuracy of language models by grounding outputs in external knowledge. As large language models are increasingly deployed in privacy-sensitive domains such as healthcare, finance, and personalized assistance, Federated RAG offers a promising framework for secure, knowledge-intensive natural language processing (NLP). To the best of our knowledge, this paper presents the first systematic mapping study of Federated RAG, covering literature published between 2020 and 2025. Following Kitchenham's guidelines for evidence-based software engineering, we develop a structured classification of research focuses, contribution types, and application domains. We analyze architectural patterns, temporal trends, and key challenges, including privacy-preserving retrieval, cross-client heterogeneity, and evaluation limitations. Our findings synthesize a rapidly evolving body of research, identify recurring design patterns, and surface open questions, providing a foundation for future work at the intersection of RAG and federated systems.
Point, Detect, Count: Multi-Task Medical Image Understanding with Instruction-Tuned Vision-Language Models
Gautam, Sushant, Riegler, Michael A., Halvorsen, Pรฅl
--We investigate fine-tuning Vision-Language Models (VLMs) for multi-task medical image understanding, focusing on detection, localization, and counting of findings in medical images. Our objective is to evaluate whether instruction-tuned VLMs can simultaneously improve these tasks, with the goal of enhancing diagnostic accuracy and efficiency. Using MedMulti-Points, a multimodal dataset with annotations from endoscopy (polyps and instruments) and microscopy (sperm cells), we reformulate each task into instruction-based prompts suitable for vision-language reasoning. Results show that multi-task training improves robustness and accuracy. For example, it reduces the Count Mean Absolute Error (MAE) and increases Matching Accuracy in the Counting + Pointing task. However, trade-offs emerge, such as more zero-case point predictions, indicating reduced reliability in edge cases despite overall performance gains. Our study highlights the potential of adapting general-purpose VLMs to specialized medical tasks via prompt-driven fine-tuning. This approach mirrors clinical workflows, where radiologists simultaneously localize, count, and describe findings - demonstrating how VLMs can learn composite diagnostic reasoning patterns. The model produces interpretable, structured outputs, offering a promising step toward explainable and versatile medical AI. Medical imaging comes with numerous challenges, such as detecting subtle abnormalities, processing images captured under varied conditions, and managing high data volumes, all of which complicate automated analysis [1].
Fine-tuning Quantized Neural Networks with Zeroth-order Optimization
Shang, Sifeng, Zhou, Jiayi, Lin, Chenyu, Li, Minxian, Zhou, Kaiyang
As the size of large language models grows exponentially, GPU memory has become a bottleneck for adapting these models to downstream tasks. In this paper, we aim to push the limits of memory-efficient training by minimizing memory usage on model weights, gradients, and optimizer states, within a unified framework. Our idea is to eliminate both gradients and optimizer states using zeroth-order optimization, which approximates gradients by perturbing weights during forward passes to identify gradient directions. To minimize memory usage on weights, we employ model quantization, e.g., converting from bfloat16 to int4. However, directly applying zeroth-order optimization to quantized weights is infeasible due to the precision gap between discrete weights and continuous gradients, which would otherwise require de-quantization and re-quantization. To overcome this challenge, we propose Quantized Zeroth-order Optimization (QZO), a simple yet effective approach that perturbs the continuous quantization scale for gradient estimation and uses a directional derivative clipping method to stabilize training. QZO is orthogonal to both scalar-based and codebook-based post-training quantization methods. Compared to full-parameter fine-tuning in 16 bits, QZO can reduce the total memory cost by more than 18$\times$ for 4-bit LLMs, and enables fine-tuning Llama-2-13B within a single 24GB GPU. Code will be released publicly.
One Shot Dominance: Knowledge Poisoning Attack on Retrieval-Augmented Generation Systems
Chang, Zhiyuan, Li, Mingyang, Jia, Xiaojun, Wang, Junjie, Huang, Yuekai, Jiang, Ziyou, Liu, Yang, Wang, Qing
Large Language Models (LLMs) enhanced with Retrieval-Augmented Generation (RAG) have shown improved performance in generating accurate responses. However, the dependence on external knowledge bases introduces potential security vulnerabilities, particularly when these knowledge bases are publicly accessible and modifiable. While previous studies have exposed knowledge poisoning risks in RAG systems, existing attack methods suffer from critical limitations: they either require injecting multiple poisoned documents (resulting in poor stealthiness) or can only function effectively on simplistic queries (limiting real-world applicability). This paper reveals a more realistic knowledge poisoning attack against RAG systems that achieves successful attacks by poisoning only a single document while remaining effective for complex multi-hop questions involving complex relationships between multiple elements. Our proposed AuthChain address three challenges to ensure the poisoned documents are reliably retrieved and trusted by the LLM, even against large knowledge bases and LLM's own knowledge. Extensive experiments across six popular LLMs demonstrate that AuthChain achieves significantly higher attack success rates while maintaining superior stealthiness against RAG defense mechanisms compared to state-of-the-art baselines.
When Thinking Fails: The Pitfalls of Reasoning for Instruction-Following in LLMs
Li, Xiaomin, Yu, Zhou, Zhang, Zhiwei, Chen, Xupeng, Zhang, Ziji, Zhuang, Yingying, Sadagopan, Narayanan, Beniwal, Anurag
Reasoning-enhanced large language models (RLLMs), whether explicitly trained for reasoning or prompted via chain-of-thought (CoT), have achieved state-of-the-art performance on many complex reasoning tasks. However, we uncover a surprising and previously overlooked phenomenon: explicit CoT reasoning can significantly degrade instruction-following accuracy. Evaluating 15 models on two benchmarks: IFEval (with simple, rule-verifiable constraints) and ComplexBench (with complex, compositional constraints), we consistently observe performance drops when CoT prompting is applied. Through large-scale case studies and an attention-based analysis, we identify common patterns where reasoning either helps (e.g., with formatting or lexical precision) or hurts (e.g., by neglecting simple constraints or introducing unnecessary content). We propose a metric, constraint attention, to quantify model focus during generation and show that CoT reasoning often diverts attention away from instruction-relevant tokens. To mitigate these effects, we introduce and evaluate four strategies: in-context learning, self-reflection, self-selective reasoning, and classifier-selective reasoning. Our results demonstrate that selective reasoning strategies, particularly classifier-selective reasoning, can substantially recover lost performance. To our knowledge, this is the first work to systematically expose reasoning-induced failures in instruction-following and offer practical mitigation strategies.
StoryReasoning Dataset: Using Chain-of-Thought for Scene Understanding and Grounded Story Generation
Oliveira, Daniel A. P., de Matos, David Martins
Visual storytelling systems struggle to maintain character identity across frames and link actions to appropriate subjects, frequently leading to referential hallucinations. These issues can be addressed through grounding of characters, objects, and other entities on the visual elements. We propose StoryReasoning, a dataset containing 4,178 stories derived from 52,016 movie images, with both structured scene analyses and grounded stories. Each story maintains character and object consistency across frames while explicitly modeling multi-frame relationships through structured tabular representations. Our approach features cross-frame object re-identification using visual similarity and face recognition, chain-of-thought reasoning for explicit narrative modeling, and a grounding scheme that links textual elements to visual entities across multiple frames. We establish baseline performance by fine-tuning Qwen2.5-VL 7B, creating Qwen Storyteller, which performs end-to-end object detection, re-identification, and landmark detection while maintaining consistent object references throughout the story. Evaluation demonstrates a reduction from 4.06 to 3.56 (-12.3%) hallucinations on average per story and an improvement in creativity from 2.58 to 3.38 (+31.0%) when compared to a non-fine-tuned model.