Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical for interpreting brain activity. This paper introduces NeuroGNN, a dynamic Graph Neural Network (GNN) framework that captures the dynamic interplay between the EEG electrode locations and the semantics of their corresponding brain regions. The specific brain region where an electrode is placed critically shapes the nature of captured EEG signals. Each brain region governs distinct cognitive functions, emotions, and sensory processing, influencing both the semantic and spatial relationships within the EEG data. Understanding and modeling these intricate brain relationships are essential for accurate and meaningful insights into brain activity. This is precisely where the proposed NeuroGNN framework excels by dynamically constructing a graph that encapsulates these evolving spatial, temporal, semantic, and taxonomic correlations to improve precision in seizure detection and classification. Our extensive experiments with real-world data demonstrate that NeuroGNN significantly outperforms existing state-of-the-art models.

This study unveils the In-Context Evolutionary Search (ICE-SEARCH) method, which is among the first works that melds large language models (LLMs) with evolutionary algorithms for feature selection (FS) tasks and demonstrates its effectiveness in Medical Predictive Analytics (MPA) applications. ICE-SEARCH harnesses the crossover and mutation capabilities inherent in LLMs within an evolutionary framework, significantly improving FS through the model's comprehensive world knowledge and its adaptability to a variety of roles. Our evaluation of this methodology spans three crucial MPA tasks: stroke, cardiovascular disease, and diabetes, where ICE-SEARCH outperforms traditional FS methods in pinpointing essential features for medical applications. ICE-SEARCH achieves State-of-the-Art (SOTA) performance in stroke prediction and diabetes prediction; the Decision-Randomized ICE-SEARCH ranks as SOTA in cardiovascular disease prediction. The study emphasizes the critical role of incorporating domain-specific insights, illustrating ICE-SEARCH's robustness, generalizability, and convergence. This opens avenues for further research into comprehensive and intricate FS landscapes, marking a significant stride in the application of artificial intelligence in medical predictive analytics.

We revisit the problem of the existence of the maximum likelihood estimate for multi-class logistic regression. We show that one method of ensuring its existence is by assigning positive probability to every class in the sample dataset. The notion of data separability is not needed, which is in contrast to the classical set up of multi-class logistic regression in which each data sample belongs to one class. We also provide a general and constructive estimate of the convergence rate to the maximum likelihood estimate when gradient descent is used as the optimizer. Our estimate involves bounding the condition number of the Hessian of the maximum likelihood function. The approaches used in this article rely on a simple operator-theoretic framework.

Instrumental variables (IVs) are a popular and powerful tool for estimating causal effects in the presence of unobserved confounding. However, classical approaches rely on strong assumptions such as the $\textit{exclusion criterion}$, which states that instrumental effects must be entirely mediated by treatments. This assumption often fails in practice. When IV methods are improperly applied to data that do not meet the exclusion criterion, estimated causal effects may be badly biased. In this work, we propose a novel solution that provides $\textit{partial}$ identification in linear systems given a set of $\textit{leaky instruments}$, which are allowed to violate the exclusion criterion to some limited degree. We derive a convex optimization objective that provides provably sharp bounds on the average treatment effect under some common forms of information leakage, and implement inference procedures to quantify the uncertainty of resulting estimates. We demonstrate our method in a set of experiments with simulated data, where it performs favorably against the state of the art. An accompanying $\texttt{R}$ package, $\texttt{leakyIV}$, is available from $\texttt{CRAN}$.

This thesis is a corpus-based, quantitative, and typological analysis of the functions of Early Slavic participle constructions and their finite competitors ($jegda$-'when'-clauses). The first part leverages detailed linguistic annotation on Early Slavic corpora at the morphosyntactic, dependency, information-structural, and lexical levels to obtain indirect evidence for different potential functions of participle clauses and their main finite competitor and understand the roles of compositionality and default discourse reasoning as explanations for the distribution of participle constructions and $jegda$-clauses in the corpus. The second part uses massively parallel data to analyze typological variation in how languages express the semantic space of English $when$, whose scope encompasses that of Early Slavic participle constructions and $jegda$-clauses. Probabilistic semantic maps are generated and statistical methods (including Kriging, Gaussian Mixture Modelling, precision and recall analysis) are used to induce cross-linguistically salient dimensions from the parallel corpus and to study conceptual variation within the semantic space of the hypothetical concept WHEN.

Predictive modeling of criminal recidivism, or whether people will re-offend in the future, has a long and contentious history. Modern causal inference methods allow us to move beyond prediction and target the "treatment effect" of a specific intervention on an outcome in an observational dataset. In this paper, we look specifically at the effect of incarceration (prison time) on recidivism, using a well-known dataset from North Carolina. Two popular causal methods for addressing confounding bias are explained and demonstrated: directed acyclic graph (DAG) adjustment and double machine learning (DML), including a sensitivity analysis for unobserved confounders. We find that incarceration has a detrimental effect on recidivism, i.e., longer prison sentences make it more likely that individuals will re-offend after release, although this conclusion should not be generalized beyond the scope of our data. We hope that this case study can inform future applications of causal inference to criminal justice analysis.

Sequential recommendation is one of the important branches of recommender system, aiming to achieve personalized recommended items for the future through the analysis and prediction of users' ordered historical interactive behaviors. However, along with the growth of the user volume and the increasingly rich behavioral information, how to understand and disentangle the user's interactive multi-intention effectively also poses challenges to behavior prediction and sequential recommendation. In light of these challenges, we propose a Contrastive Learning sequential recommendation method based on Multi-Intention Disentanglement (MIDCL). In our work, intentions are recognized as dynamic and diverse, and user behaviors are often driven by current multi-intentions, which means that the model needs to not only mine the most relevant implicit intention for each user, but also impair the influence from irrelevant intentions. Therefore, we choose Variational Auto-Encoder (VAE) to realize the disentanglement of users' multi-intentions. We propose two types of contrastive learning paradigms for finding the most relevant user's interactive intention, and maximizing the mutual information of positive sample pairs, respectively. Experimental results show that MIDCL not only has significant superiority over most existing baseline methods, but also brings a more interpretable case to the research about intention-based prediction and recommendation.

Our study presents a framework for predicting image-based social media content popularity that focuses on addressing complex image information and a hierarchical data structure. We utilize the Google Cloud Vision API to effectively extract key image and color information from users' postings, achieving 6.8% higher accuracy compared to using non-image covariates alone. For prediction, we explore a wide range of prediction models, including Linear Mixed Model, Support Vector Regression, Multi-layer Perceptron, Random Forest, and XGBoost, with linear regression as the benchmark. Our comparative study demonstrates that models that are capable of capturing the underlying nonlinear interactions between covariates outperform other methods.

This paper introduces a novel uncertainty quantification framework for regression models where the response takes values in a separable metric space, and the predictors are in a Euclidean space. The proposed algorithms can efficiently handle large datasets and are agnostic to the predictive base model used. Furthermore, the algorithms possess asymptotic consistency guarantees and, in some special homoscedastic cases, we provide non-asymptotic guarantees. To illustrate the effectiveness of the proposed uncertainty quantification framework, we use a linear regression model for metric responses (known as the global Fr\'echet model) in various clinical applications related to precision and digital medicine. The different clinical outcomes analyzed are represented as complex statistical objects, including multivariate Euclidean data, Laplacian graphs, and probability distributions.

We describe a fast computation method for leave-one-out cross-validation (LOOCV) for $k$-nearest neighbours ($k$-NN) regression. We show that, under a tie-breaking condition for nearest neighbours, the LOOCV estimate of the mean square error for $k$-NN regression is identical to the mean square error of $(k+1)$-NN regression evaluated on the training data, multiplied by the scaling factor $(k+1)^2/k^2$. Therefore, to compute the LOOCV score, one only needs to fit $(k+1)$-NN regression only once, and does not need to repeat training-validation of $k$-NN regression for the number of training data. Numerical experiments confirm the validity of the fast computation method.