Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited uncertainty awareness. This study presents a comprehensive evaluation of DL-based skin lesion classification with transfer learning and uncertainty quantification (UQ) on the HAM10000 dataset. We benchmark several pre-trained feature extractors -- including CLIP variants, ResNet50, DenseNet121, VGG16, and EfficientNet-V2-Large -- combined with traditional classifiers such as SVM, XGBoost, and logistic regression. Multiple principal component analysis (PCA) settings (64, 128, 256, 512) are explored, with LAION CLIP ViT-H/14 and ViT-L/14 at PCA-256 achieving the strongest baseline results. In the UQ phase, Monte Carlo Dropout (MCD), Ensemble, and Ensemble Monte Carlo Dropout (EMCD) are applied and evaluated using uncertainty-aware metrics (UAcc, USen, USpe, UPre). Ensemble methods with PCA-256 provide the best balance between accuracy and reliability. Further improvements are obtained through feature fusion of top-performing extractors at PCA-256. Finally, we propose a feature-fusion based model trained with a predictive entropy (PE) loss function, which outperforms all prior configurations across both standard and uncertainty-aware evaluations, advancing trustworthy DL-based skin cancer diagnosis.

We introduce $Urania$, a novel framework for generating insights about LLM chatbot interactions with rigorous differential privacy (DP) guarantees. The framework employs a private clustering mechanism and innovative keyword extraction methods, including frequency-based, TF-IDF-based, and LLM-guided approaches. By leveraging DP tools such as clustering, partition selection, and histogram-based summarization, $Urania$ provides end-to-end privacy protection. Our evaluation assesses lexical and semantic content preservation, pair similarity, and LLM-based metrics, benchmarking against a non-private Clio-inspired pipeline (Tamkin et al., 2024). Moreover, we develop a simple empirical privacy evaluation that demonstrates the enhanced robustness of our DP pipeline. The results show the framework's ability to extract meaningful conversational insights while maintaining stringent user privacy, effectively balancing data utility with privacy preservation.

Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro fertilization-embryo transfer (IVF-ET) procedures still encounter significant hurdles in enhancing pregnancy success rates. Key challenges include the inherent subjectivity in embryo grading and the inefficiency of multi-modal data integration. Against this backdrop, the adoption of AI-driven technologies has emerged as a pivotal strategy to address these issues. This article presents a comprehensive review of the progress in AI applications for embryo grading and pregnancy prediction from a novel perspective, with a specific focus on the utilization of different modal data, such as static images, time-lapse videos, and structured tabular data. The reason for this perspective is that reorganizing tasks based on data sources can not only more accurately depict the essence of the problem but also help clarify the rationality and limitations of model design. Furthermore, this review critically examines the core challenges in contemporary research, encompassing the intricacies of multi-modal feature fusion, constraints imposed by data scarcity, limitations in model generalization capabilities, and the dynamically evolving legal and regulatory frameworks. On this basis, it explicitly identifies potential avenues for future research, aiming to provide actionable guidance for advancing the application of multi-modal AI in the field of ART.

Existing molecular machine learning force fields (MLFFs) generally focus on the learning of atoms, molecules, and simple quantum chemical properties (such as energy and force), but ignore the importance of electron density (ED) $ρ(r)$ in accurately understanding molecular force fields (MFFs). ED describes the probability of finding electrons at specific locations around atoms or molecules, which uniquely determines all ground state properties (such as energy, molecular structure, etc.) of interactive multi-particle systems according to the Hohenberg-Kohn theorem. However, the calculation of ED relies on the time-consuming first-principles density functional theory (DFT) which leads to the lack of large-scale ED data and limits its application in MLFFs. In this paper, we introduce EDBench, a large-scale, high-quality dataset of ED designed to advance learning-based research at the electronic scale. Built upon the PCQM4Mv2, EDBench provides accurate ED data, covering 3.3 million molecules. To comprehensively evaluate the ability of models to understand and utilize electronic information, we design a suite of ED-centric benchmark tasks spanning prediction, retrieval, and generation. Our evaluation on several state-of-the-art methods demonstrates that learning from EDBench is not only feasible but also achieves high accuracy. Moreover, we show that learning-based method can efficiently calculate ED with comparable precision while significantly reducing the computational cost relative to traditional DFT calculations. All data and benchmarks from EDBench will be freely available, laying a robust foundation for ED-driven drug discovery and materials science.

Deep learning on graphs has shown remarkable success across numerous applications, including social networks, bio-physics, traffic networks, and recommendation systems. Regardless of their successes, current methods frequently depend on the assumption that training and testing data share the same distribution, a condition rarely met in real-world scenarios. While graph-transformer (GT) backbones have recently outperformed traditional message-passing neural networks (MPNNs) in multiple in-distribution (ID) benchmarks, their effectiveness under distribution shifts remains largely unexplored. In this work, we address the challenge of out-of-distribution (OOD) generalization for graph neural networks, with a special focus on the impact of backbone architecture. We systematically evaluate GT and hybrid backbones in OOD settings and compare them to MPNNs. To do so, we adapt several leading domain generalization (DG) algorithms to work with GTs and assess their performance on a benchmark designed to test a variety of distribution shifts. Our results reveal that GT and hybrid GT-MPNN backbones demonstrate stronger generalization ability compared to MPNNs, even without specialized DG algorithms (on four out of six benchmarks). Additionally, we propose a novel post-training analysis approach that compares the clustering structure of the entire ID and OOD test datasets, specifically examining domain alignment and class separation. Highlighting its model-agnostic design, the method yielded valuable insights into both GT and MPNN backbones and appears well suited for broader DG applications beyond graph learning, offering a deeper perspective on generalization abilities that goes beyond standard accuracy metrics. Together, our findings highlight the promise of graph-transformers for robust, real-world graph learning and set a new direction for future research in OOD generalization.

Vehicular Ad Hoc Networks (VANETs) play a key role in Intelligent Transportation Systems (ITS), particularly in enabling real-time communication for emergency vehicles. However, Distributed Denial of Service (DDoS) attacks, which interfere with safety-critical communication channels, can severely impair their reliability. This study introduces a robust and scalable framework to detect DDoS attacks in highway-based VANET environments. A synthetic dataset was constructed using Network Simulator 3 (NS-3) in conjunction with the Simulation of Urban Mobility (SUMO) and further enriched with real-world mobility traces from Germany's A81 highway, extracted via OpenStreetMap (OSM). Three traffic categories were simulated: DDoS, VoIP, and TCP-based video streaming (VideoTCP). The data preprocessing pipeline included normalization, signal-to-noise ratio (SNR) feature engineering, missing value imputation, and class balancing using the Synthetic Minority Over-sampling Technique (SMOTE). Feature importance was assessed using SHapley Additive exPlanations (SHAP). Eleven classifiers were benchmarked, among them XGBoost (XGB), CatBoost (CB), AdaBoost (AB), GradientBoosting (GB), and an Artificial Neural Network (ANN). XGB and CB achieved the best performance, each attaining an F1-score of 96%. These results highlight the robustness of the proposed framework and its potential for real-time deployment in VANETs to secure critical emergency communications.

Backchannels and fillers are important linguistic expressions in dialogue, but are under-represented in modern transformer-based language models (LMs). Our work studies the representation of them in language models using three fine-tuning strategies. The models are trained on three dialogue corpora in English and Japanese, where backchannels and fillers are preserved and annotated, to investigate how fine-tuning can help LMs learn their representations. We first apply clustering analysis to the learnt representation of backchannels and fillers, and have found increased silhouette scores in representations from fine-tuned models, which suggests that fine-tuning enables LMs to distinguish the nuanced semantic variation in different backchannel and filler use. We also use natural language generation (NLG) metrics to confirm that the utterances generated by fine-tuned language models resemble human-produced utterances more closely. Our findings suggest the potentials of transforming general LMs into conversational LMs that are more capable of producing human-like languages adequately.

We present Federation of Agents (FoA), a distributed orchestration framework that transforms static multi-agent coordination into dynamic, capability-driven collaboration. FoA introduces Versioned Capability Vectors (VCVs): machine-readable profiles that make agent capabilities searchable through semantic embeddings, enabling agents to advertise their capabilities, cost, and limitations. Our aarchitecturecombines three key innovations: (1) semantic routing that matches tasks to agents over sharded HNSW indices while enforcing operational constraints through cost-biased optimization, (2) dynamic task decomposition where compatible agents collaboratively break down complex tasks into DAGs of subtasks through consensus-based merging, and (3) smart clustering that groups agents working on similar subtasks into collaborative channels for k-round refinement before synthesis. Built on top of MQTT,s publish-subscribe semantics for scalable message passing, FoA achieves sub-linear complexity through hierarchical capability matching and efficient index maintenance. Evaluation on HealthBench shows 13x improvements over single-model baselines, with clustering-enhanced laboration particularly effective for complex reasoning tasks requiring multiple perspectives. The system scales horizontally while maintaining consistent performance, demonstrating that semantic orchestration with structured collaboration can unlock the collective intelligence of heterogeneous federations of AI agents.

Linguistic feature datasets such as URIEL+ are valuable for modelling cross-lingual relationships, but their high dimensionality and sparsity, especially for low-resource languages, limit the effectiveness of distance metrics. We propose a pipeline to optimize the URIEL+ typological feature space by combining feature selection and imputation, producing compact yet interpretable typological representations. We evaluate these feature subsets on linguistic distance alignment and downstream tasks, demonstrating that reduced-size representations of language typology can yield more informative distance metrics and improve performance in multilingual NLP applications.

Artificial Intelligence is increasingly pervasive across domains, with ever more complex models delivering impressive predictive performance. This fast technological advancement however comes at a concerning environmental cost, with state-of-the-art models - particularly deep neural networks and large language models - requiring substantial computational resources and energy. In this work, we present the intuition of Green AI dynamic model selection, an approach based on dynamic model selection that aims at reducing the environmental footprint of AI by selecting the most sustainable model while minimizing potential accuracy loss. Specifically, our approach takes into account the inference task, the environmental sustainability of available models, and accuracy requirements to dynamically choose the most suitable model. Our approach presents two different methods, namely Green AI dynamic model cascading and Green AI dynamic model routing. We demonstrate the effectiveness of our approach via a proof of concept empirical example based on a real-world dataset. Our results show that Green AI dynamic model selection can achieve substantial energy savings (up to ~25%) while substantially retaining the accuracy of the most energy greedy solution (up to ~95%). As conclusion, our preliminary findings highlight the potential that hybrid, adaptive model selection strategies withhold to mitigate the energy demands of modern AI systems without significantly compromising accuracy requirements.