This paper presents the Multimodal Analyzing System for Laryngoscope (MASL), a system that combines audio and video data to automatically extract key segments and metrics from laryngeal videostroboscopic videos for clinical assessment. MASL integrates glottis detection with keyword spotting to analyze patient vocalizations and refine video highlights for better inspection of vocal cord movements. The system includes a strobing video extraction module that identifies frames by analyzing hue, saturation, and value fluctuations. MASL also provides effective metrics for vocal cord paralysis detection, employing a two-stage glottis segmentation process using U-Net followed by diffusion-based refinement to reduce false positives. Instead of glottal area waveforms, MASL estimates anterior glottic angle waveforms (AGAW) from glottis masks, evaluating both left and right vocal cords to detect unilateral vocal cord paralysis (UVFP). By comparing AGAW variances, MASL distinguishes between left and right paralysis. Ablation studies and experiments on public and real-world datasets validate MASL's segmentation module and demonstrate its ability to provide reliable metrics for UVFP diagnosis.

Prediction models inform important clinical decisions, aiding in diagnosis, prognosis, and treatment planning. The predictive performance of these models is typically assessed through discrimination and calibration. However, changes in the distribution of the data impact model performance. In health-care, a typical change is a shift in case-mix: for example, for cardiovascular risk management, a general practitioner sees a different mix of patients than a specialist in a tertiary hospital. This work introduces a novel framework that differentiates the effects of case-mix shifts on discrimination and calibration based on the causal direction of the prediction task. When prediction is in the causal direction (often the case for prognosis predictions), calibration remains stable under case-mix shifts, while discrimination does not. Conversely, when predicting in the anti-causal direction (often with diagnosis predictions), discrimination remains stable, but calibration does not. A simulation study and empirical validation using cardiovascular disease prediction models demonstrate the implications of this framework. This framework provides critical insights for evaluating and deploying prediction models across different clinical settings, emphasizing the importance of understanding the causal structure of the prediction task.

Increased usage of automated tools like deep learning in medical image segmentation has alleviated the bottleneck of manual contouring. This has shifted manual labour to quality assessment (QA) of automated contours which involves detecting errors and correcting them. A potential solution to semi-automated QA is to use deep Bayesian uncertainty to recommend potentially erroneous regions, thus reducing time spent on error detection. Previous work has investigated the correspondence between uncertainty and error, however, no work has been done on improving the "utility" of Bayesian uncertainty maps such that it is only present in inaccurate regions and not in the accurate ones. Our work trains the FlipOut model with the Accuracy-vs-Uncertainty (AvU) loss which promotes uncertainty to be present only in inaccurate regions. We apply this method on datasets of two radiotherapy body sites, c.f. head-and-neck CT and prostate MR scans. Uncertainty heatmaps (i.e. predictive entropy) are evaluated against voxel inaccuracies using Receiver Operating Characteristic (ROC) and Precision-Recall (PR) curves. Numerical results show that when compared to the Bayesian baseline the proposed method successfully suppresses uncertainty for accurate voxels, with similar presence of uncertainty for inaccurate voxels. Code to reproduce experiments is available at https://github.com/prerakmody/bayesuncertainty-error-correspondence

Given the societal impact of unsafe content generated by large language models (LLMs), ensuring that LLM services comply with safety standards is a crucial concern for LLM service providers. Common content moderation methods are limited by an effectiveness-and-efficiency dilemma, where simple models are fragile while sophisticated models consume excessive computational resources. In this paper, we reveal for the first time that effective and efficient content moderation can be achieved by extracting conceptual features from chat-oriented LLMs, despite their initial fine-tuning for conversation rather than content moderation. We propose a practical and unified content moderation framework for LLM services, named Legilimens, which features both effectiveness and efficiency. Our red-team model-based data augmentation enhances the robustness of Legilimens against state-of-the-art jailbreaking. Additionally, we develop a framework to theoretically analyze the cost-effectiveness of Legilimens compared to other methods. We have conducted extensive experiments on five host LLMs, seventeen datasets, and nine jailbreaking methods to verify the effectiveness, efficiency, and robustness of Legilimens against normal and adaptive adversaries. A comparison of Legilimens with both commercial and academic baselines demonstrates the superior performance of Legilimens. Furthermore, we confirm that Legilimens can be applied to few-shot scenarios and extended to multi-label classification tasks.

With the emergence of widely available powerful LLMs, disinformation generated by large Language Models (LLMs) has become a major concern. Historically, LLM detectors have been touted as a solution, but their effectiveness in the real world is still to be proven. In this paper, we focus on an important setting in information operations -- short news-like posts generated by moderately sophisticated attackers. We demonstrate that existing LLM detectors, whether zero-shot or purpose-trained, are not ready for real-world use in that setting. All tested zero-shot detectors perform inconsistently with prior benchmarks and are highly vulnerable to sampling temperature increase, a trivial attack absent from recent benchmarks. A purpose-trained detector generalizing across LLMs and unseen attacks can be developed, but it fails to generalize to new human-written texts. We argue that the former indicates domain-specific benchmarking is needed, while the latter suggests a trade-off between the adversarial evasion resilience and overfitting to the reference human text, with both needing evaluation in benchmarks and currently absent. We believe this suggests a re-consideration of current LLM detector benchmarking approaches and provides a dynamically extensible benchmark to allow it (https://github.com/Reliable-Information-Lab-HEVS/dynamic_llm_detector_benchmark).

We demonstrate mechanical threats classification including jackhammers and excavators, leveraging wavelet transform of MIMO-DFS output data across a 57-km operational network link. Our machine learning framework incorporates transfer learning and shows 93% classification accuracy from field data, with benefits for optical network supervision.

Analyzing large datasets to select optimal features is one of the most important research areas in machine learning and data mining. This feature selection procedure involves dimensionality reduction which is crucial in enhancing the performance of the model, making it less complex. Recently, several types of attribute selection methods have been proposed that use different approaches to obtain representative subsets of the attributes. However, population-based evolutionary algorithms like Genetic Algorithms (GAs) have been proposed to provide remedies for these drawbacks by avoiding local optima and improving the selection process itself. This manuscript presents a sweeping review on GA-based feature selection techniques in applications and their effectiveness across different domains. This review was conducted using the PRISMA methodology; hence, the systematic identification, screening, and analysis of relevant literature were performed. Thus, our results hint that the field's hybrid GA methodologies including, but not limited to, GA-Wrapper feature selector and HGA-neural networks, have substantially improved their potential through the resolution of problems such as exploration of unnecessary search space, accuracy performance problems, and complexity. The conclusions of this paper would result in discussing the potential that GAs bear in feature selection and future research directions for their enhancement in applicability and performance.

High rates of false positive test results may be keeping women from sticking to recommended mammogram screenings for breast cancer, a new study has found. Researchers from UC Davis Comprehensive Cancer Center in Sacramento, California, reviewed more than 3.5 million screening mammograms performed among more than one million women between 2005 and 2017. Women who received a true-negative result were more likely to return for future screenings, with a 77% compliance rate. THESE 17 CANCER TYPES ARE MORE COMMON IN GEN X AND MILLENNIALS, AS STUDY NOTES'ALARMING TREND' By comparison, among those who received a false positive, only 61% returned for another mammogram in six months, and 67% returned for a recommended biopsy. The women, who ranged in age from 40 to 73, had not previously received a breast cancer diagnosis.

Neural networks (NN) classification models for Natural Language Processing (NLP) are vulnerable to the Universal Adversarial Triggers (UAT) attack that triggers a model to produce a specific prediction for any input. DARCY borrows the "honeypot" concept to bait multiple trapdoors, effectively detecting the adversarial examples generated by UAT. Unfortunately, we find a new UAT generation method, called IndisUAT, which produces triggers (i.e., tokens) and uses them to craft adversarial examples whose feature distribution is indistinguishable from that of the benign examples in a randomly-chosen category at the detection layer of DARCY. The produced adversarial examples incur the maximal loss of predicting results in the DARCY-protected models. Meanwhile, the produced triggers are effective in black-box models for text generation, text inference, and reading comprehension. Finally, the evaluation results under NN models for NLP tasks indicate that the IndisUAT method can effectively circumvent DARCY and penetrate other defenses. For example, IndisUAT can reduce the true positive rate of DARCY's detection by at least 40.8% and 90.6%, and drop the accuracy by at least 33.3% and 51.6% in the RNN and CNN models, respectively. IndisUAT reduces the accuracy of the BERT's adversarial defense model by at least 34.0%, and makes the GPT-2 language model spew racist outputs even when conditioned on non-racial context.

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. In the United States, more than 15.7 million Americans have been diagnosed with COPD, with 96% of individuals living with at least one other chronic health condition. It is the 4th leading cause of death in the country. Over 2.2 million patients are admitted to hospitals annually due to COPD exacerbations. Monitoring and predicting patient exacerbations on-time could save their life. This paper presents two different predictive models to predict COPD exacerbation using AI and natural language processing (NLP) approaches. These models use respiration summary notes, symptoms, and vital signs. To train and test these models, data records containing physiologic signals and vital signs time series were used. These records were captured from patient monitors and comprehensive clinical data obtained from hospital medical information systems for tens of thousands of Intensive Care Unit (ICU) patients. We achieved an area under the Receiver operating characteristic (ROC) curve of 0.82 in detection and prediction of COPD exacerbation.