Advancements in onboard computing mean remote sensing agents can employ state-of-the-art computer vision and machine learning at the edge. These capabilities can be leveraged to unlock new rare, transient, and pinpoint measurements of dynamic science phenomena. In this paper, we present an automated workflow that synthesizes the detection of these dynamic events in look-ahead satellite imagery with autonomous trajectory planning for a follow-up high-resolution sensor to obtain pinpoint measurements. We apply this workflow to the use case of observing volcanic plumes. We analyze classification approaches including traditional machine learning algorithms and convolutional neural networks. We present several trajectory planning algorithms that track the morphological features of a plume and integrate these algorithms with the classifiers. We show through simulation an order of magnitude increase in the utility return of the high-resolution instrument compared to baselines while maintaining efficient runtimes.

Accurate identification of interactions between protein residues and ligand functional groups is essential to understand molecular recognition and guide rational drug design. Existing deep learning approaches for protein-ligand interpretability often rely on 3D structural input or use distance-based contact labels, limiting both their applicability and biological relevance. We introduce LINKER, the first sequence-based model to predict residue-functional group interactions in terms of biologically defined interaction types, using only protein sequences and the ligand SMILES as input. LINKER is trained with structure-supervised attention, where interaction labels are derived from 3D protein-ligand complexes via functional group-based motif extraction. By abstracting ligand structures into functional groups, the model focuses on chemically meaningful substructures while predicting interaction types rather than mere spatial proximity. Crucially, LINKER requires only sequence-level input at inference time, enabling large-scale application in settings where structural data is unavailable. Experiments on the LP-PDBBind benchmark demonstrate that structure-informed supervision over functional group abstractions yields interaction predictions closely aligned with ground-truth biochemical annotations.

In this study we analyzed average sleep durations across 61 countries to examine the impact of Daylight Saving Time (DST) practices. Key metrics influencing sleep were identified, and statistical correlation analysis was applied to explore relationships among these factors. Countries were grouped based on DST observance, and visualizations compared sleep patterns between DST and non-DST regions. Results show that, on average, countries observing DST tend to report longer sleep durations than those that do not. A more detailed pattern emerged when accounting for latitude: at lower latitudes, DST-observing countries reported shorter sleep durations compared to non-DST countries, while at higher latitudes, DST-observing countries reported longer average sleep durations. These findings suggest that the influence of DST on sleep may be moderated by geographical location.

Generative Adversarial Networks (GANs) and diffusion models have emerged as leading approaches for high-quality image synthesis. While both can be trained under differential privacy (DP) to protect sensitive data, their sensitivity to membership inference attacks (MIAs), a key threat to data confidentiality, remains poorly understood. In this work, we present the first unified theoretical and empirical analysis of the privacy risks faced by differentially private generative models. We begin by showing, through a stability-based analysis, that GANs exhibit fundamentally lower sensitivity to data perturbations than diffusion models, suggesting a structural advantage in resisting MIAs. We then validate this insight with a comprehensive empirical study using a standardized MIA pipeline to evaluate privacy leakage across datasets and privacy budgets. Our results consistently reveal a marked privacy robustness gap in favor of GANs, even in strong DP regimes, highlighting that model type alone can critically shape privacy leakage.

Abnormal cryptocurrency transactions - such as mixing services, fraudulent transfers, and pump-and-dump operations -- pose escalating risks to financial integrity but remain notoriously difficult to detect due to class imbalance, temporal volatility, and complex network dependencies. Existing approaches are predominantly model-centric and post hoc, flagging anomalies only after they occur and thus offering limited preventive value. This paper introduces HyPV-LEAD (Hyperbolic Peak-Valley Lead-time Enabled Anomaly Detection), a data-driven early-warning framework that explicitly incorporates lead time into anomaly detection. Unlike prior methods, HyPV-LEAD integrates three innovations: (1) window-horizon modeling to guarantee actionable lead-time alerts, (2) Peak-Valley (PV) sampling to mitigate class imbalance while preserving temporal continuity, and (3) hyperbolic embedding to capture the hierarchical and scale-free properties of blockchain transaction networks. Empirical evaluation on large-scale Bitcoin transaction data demonstrates that HyPV-LEAD consistently outperforms state-of-the-art baselines, achieving a PR-AUC of 0.9624 with significant gains in precision and recall. Ablation studies further confirm that each component - PV sampling, hyperbolic embedding, and structural-temporal modeling - provides complementary benefits, with the full framework delivering the highest performance. By shifting anomaly detection from reactive classification to proactive early-warning, HyPV-LEAD establishes a robust foundation for real-time risk management, anti-money laundering (AML) compliance, and financial security in dynamic blockchain environments.

Poisoning attacks pose an increasing threat to the security and robustness of Artificial Intelligence systems in the military domain. The widespread use of open-source datasets and pretrained models exacerbates this risk. Despite the severity of this threat, there is limited research on the application and detection of poisoning attacks on object detection systems. This is especially problematic in the military domain, where attacks can have grave consequences. In this work, we both investigate the effect of poisoning attacks on military object detectors in practice, and the best approach to detect these attacks. To support this research, we create a small, custom dataset featuring military vehicles: MilCivVeh. We explore the vulnerability of military object detectors for poisoning attacks by implementing a modified version of the BadDet attack: a patch-based poisoning attack. We then assess its impact, finding that while a positive attack success rate is achievable, it requires a substantial portion of the data to be poisoned -- raising questions about its practical applicability. To address the detection challenge, we test both specialized poisoning detection methods and anomaly detection methods from the visual industrial inspection domain. Since our research shows that both classes of methods are lacking, we introduce our own patch detection method: AutoDetect, a simple, fast, and lightweight autoencoder-based method. Our method shows promising results in separating clean from poisoned samples using the reconstruction error of image slices, outperforming existing methods, while being less time- and memory-intensive. We urge that the availability of large, representative datasets in the military domain is a prerequisite to further evaluate risks of poisoning attacks and opportunities patch detection.

This study demonstrates that a Multimodal Large Language Model (MLLM) adapted via Low-Rank Adaptation (LoRA) can perform both Automatic Pronunciation Assessment (APA) and Mispronunciation Detection and Diagnosis (MDD) simultaneously. Leveraging Microsoft's Phi-4-multimodal-instruct, our fine-tuning method eliminates the need for complex architectural changes or separate training procedures conventionally required for these distinct tasks. Fine-tuned on the Speechocean762 dataset, the pronunciation evaluation scores predicted by the model exhibited a strong Pearson Correlation Coefficient (PCC > 0.7) with human-assigned scores, while achieving low Word Error Rate (WER) and Phoneme Error Rate (PER) (both < 0.15). Notably, fine-tuning only the LoRA layers was sufficient to achieve performance levels comparable to those achieved by fine-tuning all audio layers. This research highlights that an integrated pronunciation assessment system can be established by adapting large multimodal models without full fine-tuning, utilizing a significantly simpler training methodology compared to previous joint models designed for simultaneous APA and MDD. This efficient LoRA-based approach paves the way for more accessible, integrated, and effective Computer-Assisted Pronunciation Training (CAPT) technologies for English L2 learners.

The MIDOG 2025 challenge extends prior work on mitotic figure detection by introducing a new Track 2 on atypical mitosis classification. This task aims to distinguish normal from atypical mitotic figures in histopathology images, a clinically relevant but highly imbalanced and cross-domain problem. We investigated two complementary backbones: (i) ConvNeXt-Small, pretrained on ImageNet, and (ii) a histopathology-specific ViT from Lunit trained via self-supervision. To address the strong prevalence imbalance (9408 normal vs. 1741 atypical), we synthesized additional atypical examples to approximate class balance and compared models trained with real-only vs. real+synthetic data. Using five-fold cross-validation, both backbones reached strong performance (mean AUROC approximately 95 percent), with ConvNeXt achieving slightly higher peaks while Lunit exhibited greater fold-to-fold stability. Synthetic balancing, however, did not lead to consistent improvements. On the organizers' preliminary hidden test set, explicitly designed as an out-of-distribution debug subset, ConvNeXt attained the highest AUROC (95.4 percent), whereas Lunit remained competitive on balanced accuracy. These findings suggest that both ImageNet and domain-pretrained backbones are viable for atypical mitosis classification, with domain-pretraining conferring robustness and ImageNet pretraining reaching higher peaks, while naive synthetic balancing has limited benefit. Full hidden test set results will be reported upon challenge completion.

Dementia (DEM) is a growing global health challenge, underscoring the need for early and accurate diagnosis. Electroencephalography (EEG) provides a non-invasive window into brain activity, but conventional methods struggle to capture its transient complexity. We present the \textbf{EEG Microstate Analysis Framework (EEG-MSAF)}, an end-to-end pipeline that leverages EEG microstates discrete, quasi-stable topographies to identify DEM-related biomarkers and distinguish DEM, mild cognitive impairment (MCI), and normal cognition (NC). EEG-MSAF comprises three stages: (1) automated microstate feature extraction, (2) classification with machine learning (ML), and (3) feature ranking using Shapley Additive Explanations (SHAP) to highlight key biomarkers. We evaluate on two EEG datasets: the public Chung-Ang University EEG (CAUEEG) dataset and a clinical cohort from Thessaloniki Hospital. Our framework demonstrates strong performance and generalizability. On CAUEEG, EEG-MSAF-SVM achieves \textbf{89\% $\pm$ 0.01 accuracy}, surpassing the deep learning baseline CEEDNET by \textbf{19.3\%}. On the Thessaloniki dataset, it reaches \textbf{95\% $\pm$ 0.01 accuracy}, comparable to EEGConvNeXt. SHAP analysis identifies mean correlation and occurrence as the most informative metrics: disruption of microstate C (salience/attention network) dominates DEM prediction, while microstate F, a novel default-mode pattern, emerges as a key early biomarker for both MCI and DEM. By combining accuracy, generalizability, and interpretability, EEG-MSAF advances EEG-based dementia diagnosis and sheds light on brain dynamics across the cognitive spectrum.

Printed electronics offer a promising alternative for applications beyond silicon-based systems, requiring properties like flexibility, stretchability, conformality, and ultra-low fabrication costs. Despite the large feature sizes in printed electronics, printed neural networks have attracted attention for meeting target application requirements, though realizing complex circuits remains challenging. This work bridges the gap between classification accuracy and area efficiency in printed neural networks, covering the entire processing-near-sensor system design and co-optimization from the analog-to-digital interface-a major area and power bottleneck-to the digital classifier. We propose an automated framework for designing printed Ternary Neural Networks with arbitrary input precision, utilizing multi-objective optimization and holistic approximation. Our circuits outperform existing approximate printed neural networks by 17x in area and 59x in power on average, being the first to enable printed-battery-powered operation with under 5% accuracy loss while accounting for analog-to-digital interfacing costs.