We study the robustness of conformal prediction, a powerful tool for uncertainty quantification, to label noise. Our analysis tackles both regression and classification problems, characterizing when and how it is possible to construct uncertainty sets that correctly cover the unobserved noiseless ground truth labels. We further extend our theory and formulate the requirements for correctly controlling a general loss function, such as the false negative proportion, with noisy labels. Our theory and experiments suggest that conformal prediction and risk-controlling techniques with noisy labels attain conservative risk over the clean ground truth labels except in adversarial cases. In such cases, we can also correct for noise of bounded size in the conformal prediction algorithm in order to ensure achieving the correct risk of the ground truth labels without score or data regularity.

Abstract--Anomalies in the domain of autonomous driving are a major hindrance to the large-scale deployment of autonomous vehicles. In this work, we focus on high-resolution camera data from urban scenes that include anomalies of various types and sizes. Based on a Variational Autoencoder, we condition its latent space to classify samples as either normal data or anomalies. In order to emphasize especially small anomalies, we perform experiments where we provide the VAE with a discrepancy map as an additional input, evaluating its impact on the detection performance. Our method separates normal data and anomalies into isolated clusters while still reconstructing high-quality images, leading to meaningful latent representations.

Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily relied on imaging analysis, yet not all patients undergo medical imaging before an ADRD diagnosis. Merging machine learning with claims data can reveal additional risk factors and uncover interconnections among diverse medical codes. Our goal is to utilize Graph Neural Networks (GNNs) with claims data for ADRD risk prediction. Addressing the lack of human-interpretable reasons behind these predictions, we introduce an innovative method to evaluate relationship importance and its influence on ADRD risk prediction, ensuring comprehensive interpretation. We employed Variationally Regularized Encoder-decoder Graph Neural Network (VGNN) for estimating ADRD likelihood. We created three scenarios to assess the model's efficiency, using Random Forest and Light Gradient Boost Machine as baselines. We further used our relation importance method to clarify the key relationships for ADRD risk prediction. VGNN surpassed other baseline models by 10% in the area under the receiver operating characteristic. The integration of the GNN model and relation importance interpretation could potentially play an essential role in providing valuable insight into factors that may contribute to or delay ADRD progression. Employing a GNN approach with claims data enhances ADRD risk prediction and provides insights into the impact of interconnected medical code relationships. This methodology not only enables ADRD risk modeling but also shows potential for other image analysis predictions using claims data.

Privacy policies serve as the primary conduit through which online service providers inform users about their data collection and usage procedures. However, in a bid to be comprehensive and mitigate legal risks, these policy documents are often quite verbose. In practical use, users tend to click the Agree button directly rather than reading them carefully. This practice exposes users to risks of privacy leakage and legal issues. Recently, the advent of Large Language Models (LLM) such as ChatGPT and GPT-4 has opened new possibilities for text analysis, especially for lengthy documents like privacy policies. In this study, we investigate a privacy policy text analysis framework PolicyGPT based on the LLM. This framework was tested using two datasets. The first dataset comprises of privacy policies from 115 websites, which were meticulously annotated by legal experts, categorizing each segment into one of 10 classes. The second dataset consists of privacy policies from 304 popular mobile applications, with each sentence manually annotated and classified into one of another 10 categories. Under zero-shot learning conditions, PolicyGPT demonstrated robust performance. For the first dataset, it achieved an accuracy rate of 97%, while for the second dataset, it attained an 87% accuracy rate, surpassing that of the baseline machine learning and neural network models.

Two prevalent types of distributional shifts in machine learning are the covariate shift (as observed across different domains) and the semantic shift (as seen across different classes). Traditional OOD detection techniques typically address only one of these shifts. However, real-world testing environments often present a combination of both covariate and semantic shifts. In this study, we introduce a novel problem, semantic OOD detection across domains, which simultaneously addresses both distributional shifts. To this end, we introduce two regularization strategies: domain generalization regularization, which ensures semantic invariance across domains to counteract the covariate shift, and OOD detection regularization, designed to enhance OOD detection capabilities against the semantic shift through energy bounding. Through rigorous testing on three standard domain generalization benchmarks, our proposed framework showcases its superiority over conventional domain generalization approaches in terms of OOD detection performance. Moreover, it holds its ground by maintaining comparable InD classification accuracy.

High-quality human transcription is essential for training and improving Automatic Speech Recognition (ASR) models. Recent study~\cite{libricrowd} has found that every 1% worse transcription Word Error Rate (WER) increases approximately 2% ASR WER by using the transcriptions to train ASR models. Transcription errors are inevitable for even highly-trained annotators. However, few studies have explored human transcription correction. Error correction methods for other problems, such as ASR error correction and grammatical error correction, do not perform sufficiently for this problem. Therefore, we propose HTEC for Human Transcription Error Correction. HTEC consists of two stages: Trans-Checker, an error detection model that predicts and masks erroneous words, and Trans-Filler, a sequence-to-sequence generative model that fills masked positions. We propose a holistic list of correction operations, including four novel operations handling deletion errors. We further propose a variant of embeddings that incorporates phoneme information into the input of the transformer. HTEC outperforms other methods by a large margin and surpasses human annotators by 2.2% to 4.5% in WER. Finally, we deployed HTEC to assist human annotators and showed HTEC is particularly effective as a co-pilot, which improves transcription quality by 15.1% without sacrificing transcription velocity.

Data augmentation is a common practice to help generalization in the procedure of deep model training. In the context of physiological time series classification, previous research has primarily focused on label-invariant data augmentation methods. However, another class of augmentation techniques (\textit{i.e., Mixup}) that emerged in the computer vision field has yet to be fully explored in the time series domain. In this study, we systematically review the mix-based augmentations, including mixup, cutmix, and manifold mixup, on six physiological datasets, evaluating their performance across different sensory data and classification tasks. Our results demonstrate that the three mix-based augmentations can consistently improve the performance on the six datasets. More importantly, the improvement does not rely on expert knowledge or extensive parameter tuning. Lastly, we provide an overview of the unique properties of the mix-based augmentation methods and highlight the potential benefits of using the mix-based augmentation in physiological time series data.

Current deep learning-based solutions for image analysis tasks are commonly incapable of handling problems to which multiple different plausible solutions exist. In response, posterior-based methods such as conditional Diffusion Models and Invertible Neural Networks have emerged; however, their translation is hampered by a lack of research on adequate validation. In other words, the way progress is measured often does not reflect the needs of the driving practical application. Closing this gap in the literature, we present the first systematic framework for the application-driven validation of posterior-based methods in inverse problems. As a methodological novelty, it adopts key principles from the field of object detection validation, which has a long history of addressing the question of how to locate and match multiple object instances in an image. Treating modes as instances enables us to perform mode-centric validation, using well-interpretable metrics from the application perspective. We demonstrate the value of our framework through instantiations for a synthetic toy example and two medical vision use cases: pose estimation in surgery and imaging-based quantification of functional tissue parameters for diagnostics. Our framework offers key advantages over common approaches to posterior validation in all three examples and could thus revolutionize performance assessment in inverse problems.

Aims. The purpose of this study is to create a multi-stage machine learning model to predict cardiac resynchronization therapy (CRT) response for heart failure (HF) patients. This model exploits uncertainty quantification to recommend additional collection of single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) variables if baseline clinical variables and features from electrocardiogram (ECG) are not sufficient. Methods. 218 patients who underwent rest-gated SPECT MPI were enrolled in this study. CRT response was defined as an increase in left ventricular ejection fraction (LVEF) > 5% at a 6 month follow-up. A multi-stage ML model was created by combining two ensemble models. Results. The response rate for CRT was 55.5% (n = 121) with overall male gender 61.0% (n = 133), an average age of 62.0, and LVEF of 27.7. The multi-stage model performed similarly to Ensemble 2 (which utilized the additional SPECT data) with AUC of 0.75 vs. 0.77, accuracy of 0.71 vs. 0.69, sensitivity of 0.70 vs. 0.72, and specificity 0.72 vs. 0.65, respectively. However, the multi-stage model only required SPECT MPI data for 52.7% of the patients across all folds. Conclusions. By using rule-based logic stemming from uncertainty quantification, the multi-stage model was able to reduce the need for additional SPECT MPI data acquisition without sacrificing performance.

In the current ML field models are getting larger and more complex, and data used for model training are also getting larger in quantity and higher in dimensions. Therefore, in order to train better models, and save training time and computational resources, a good Feature Selection (FS) method in the preprocessing stage is necessary. Feature importance (FI) is of great importance since it is the basis of feature selection. Therefore, this paper creatively introduces the calculation of PN (the probability of Necessity), PN (the probability of Sufficiency), and PNS (the probability of Necessity and Sufficiency) of Causality into quantifying feature importance and creates 3 new FI measuring methods---- PN-FI, which means how much importance a feature has in image recognition tasks, PS-FI that means how much importance a feature has in image generating tasks, and PNS-FI which measures both. The main body of this paper is three RCTs, with whose results we show how PS-FI, PN-FI, and PNS-FI of 3 features----dog nose, dog eyes, and dog mouth are calculated. The experiments show that firstly, FI values are intervals with tight upper and lower bounds. Secondly, the feature dog eyes has the most importance while the other two have almost the same. Thirdly, the bounds of PNS and PN are tighter than that of PS's.