We consider Bayesian variable selection for binary outcomes under a probit link with a spike-and-slab prior on the regression coefficients. Motivated by the computational challenges encountered by Markov chain Monte Carlo (MCMC) samplers in high-dimensional regimes, we develop a mean-field variational Bayes approximation in which all variational factors admit closed-form updates, and the evidence lower bound is available in closed form. This, in turn, allows the development of an efficient coordinate ascent variational inference algorithm to find the optimal values of the variational parameters. The approach produces posterior inclusion probabilities and parameter estimates, enabling interpretable selection and prediction within a single framework. As shown in both simulated and real data applications, the proposed method successfully identifies the important variables and is orders of magnitude faster than MCMC, while maintaining comparable accuracy.

Learning causal structures from observational data remains a fundamental yet computationally intensive task, particularly in high-dimensional settings where existing methods face challenges such as the super-exponential growth of the search space and increasing computational demands. To address this, we introduce VISTA (Voting-based Integration of Subgraph Topologies for Acyclicity), a modular framework that decomposes the global causal structure learning problem into local subgraphs based on Markov Blankets. The global integration is achieved through a weighted voting mechanism that penalizes low-support edges via exponential decay, filters unreliable ones with an adaptive threshold, and ensures acyclicity using a Feedback Arc Set (FAS) algorithm. The framework is model-agnostic, imposing no assumptions on the inductive biases of base learners, is compatible with arbitrary data settings without requiring specific structural forms, and fully supports parallelization. We also theoretically establish finite-sample error bounds for VISTA, and prove its asymptotic consistency under mild conditions. Extensive experiments on both synthetic and real datasets consistently demonstrate the effectiveness of VISTA, yielding notable improvements in both accuracy and efficiency over a wide range of base learners.

Modern industrial and service processes generate high-dimensional, non-Gaussian, and contamination-prone data that challenge the foundational assumptions of classical Statistical Process Control (SPC). Heavy tails, multimodality, nonlinear dependencies, and sparse special-cause observations can distort baseline estimation, mask true anomalies, and prevent reliable identification of an in-control (IC) reference set. To address these challenges, we introduce VSCOUT, a distribution-free framework designed specifically for retrospective (Phase I) monitoring in high-dimensional settings. VSCOUT combines an Automatic Relevance Determination Variational Autoencoder (ARD-VAE) architecture with ensemble-based latent outlier filtering and changepoint detection. The ARD prior isolates the most informative latent dimensions, while the ensemble and changepoint filters identify pointwise and structural contamination within the determined latent space. A second-stage retraining step removes flagged observations and re-estimates the latent structure using only the retained inliers, mitigating masking and stabilizing the IC latent manifold. This two-stage refinement produces a clean and reliable IC baseline suitable for subsequent Phase II deployment. Extensive experiments across benchmark datasets demonstrate that VSCOUT achieves superior sensitivity to special-cause structure while maintaining controlled false alarms, outperforming classical SPC procedures, robust estimators, and modern machine-learning baselines. Its scalability, distributional flexibility, and resilience to complex contamination patterns position VSCOUT as a practical and effective method for retrospective modeling and anomaly detection in AI-enabled environments.

We study model-agnostic post-hoc calibration methods intended to improve probabilistic predictions in supervised binary classification on real i.i.d. tabular data, with particular emphasis on conformal and Venn-based approaches that provide distribution-free validity guarantees under exchangeability. We benchmark 21 widely used classifiers, including linear models, SVMs, tree ensembles (CatBoost, XGBoost, LightGBM), and modern tabular neural and foundation models, on binary tasks from the TabArena-v0.1 suite using randomized, stratified five-fold cross-validation with a held-out test fold. Five calibrators; Isotonic regression, Platt scaling, Beta calibration, Venn-Abers predictors, and Pearsonify are trained on a separate calibration split and applied to test predictions. Calibration is evaluated using proper scoring rules (log-loss and Brier score) and diagnostic measures (Spiegelhalter's Z, ECE, and ECI), alongside discrimination (AUC-ROC) and standard classification metrics. Across tasks and architectures, Venn-Abers predictors achieve the largest average reductions in log-loss, followed closely by Beta calibration, while Platt scaling exhibits weaker and less consistent effects. Beta calibration improves log-loss most frequently across tasks, whereas Venn-Abers displays fewer instances of extreme degradation and slightly more instances of extreme improvement. Importantly, we find that commonly used calibration procedures, most notably Platt scaling and isotonic regression, can systematically degrade proper scoring performance for strong modern tabular models. Overall classification performance is often preserved, but calibration effects vary substantially across datasets and architectures, and no method dominates uniformly. In expectation, all methods except Pearsonify slightly increase accuracy, but the effect is marginal, with the largest expected gain about 0.008%.

Machine learning models in high-stakes applications, such as recidivism prediction and automated personnel selection, often exhibit systematic performance disparities across sensitive subpopulations, raising critical concerns regarding algorithmic bias. Fairness auditing addresses these risks through two primary functions: certification, which verifies adherence to fairness constraints; and flagging, which isolates specific demographic groups experiencing disparate treatment. However, existing auditing techniques are frequently limited by restrictive distributional assumptions or prohibitive computational overhead. We propose a novel empirical likelihood-based (EL) framework that constructs robust statistical measures for model performance disparities. Unlike traditional methods, our approach is non-parametric; the proposed disparity statistics follow asymptotically chi-square or mixed chi-square distributions, ensuring valid inference without assuming underlying data distributions. This framework uses a constrained optimization profile that admits stable numerical solutions, facilitating both large-scale certification and efficient subpopulation discovery. Empirically, the EL methods outperform bootstrap-based approaches, yielding coverage rates closer to nominal levels while reducing computational latency by several orders of magnitude. We demonstrate the practical utility of this framework on the COMPAS dataset, where it successfully flags intersectional biases, specifically identifying a significantly higher positive prediction rate for African-American males under 25 and a systemic under-prediction for Caucasian females relative to the population mean.

Imputing missing node features in graphs is challenging, particularly under high missing rates. Existing methods based on latent representations or global diffusion often fail to produce reliable estimates, and may propagate errors across the graph. We propose FSD-CAP, a two-stage framework designed to improve imputation quality under extreme sparsity. A fractional diffusion operator adjusts propagation sharpness based on local structure. In the second stage, imputed features are refined using class-aware propagation, which incorporates pseudo-labels and neighborhood entropy to promote consistency. We evaluated FSD-CAP on multiple datasets. With 99 .5% of features missing across five benchmark datasets, FSD-CAP achieves average accuracies of 80 .06% For link prediction under the same setting, it reaches AUC scores of 91. Furthermore, FSD-CAP demonstrates superior performance on both large-scale and heterophily datasets when compared to other models. Graph Neural Networks (GNNs) are widely used for learning from graph-structured data, with successful applications in social networks (Bian et al., 2020), biology (Li et al., 2022), and recommendation systems (He et al., 2020). GNN architectures(Chen et al., 2023; Chien et al., 2020) always assume nodal features are fully observed, allowing information to be aggregated effectively from neighboring nodes. In practice, this assumption often fails. Node attributes are frequently missing due to privacy constraints, sensor failures, or incomplete data collection. High missing rates disrupt the message-passing process and significantly degrade model performance. A variety of methods have been proposed for imputing missing features, including statistical estimators (Srebro et al., 2004), machine learning models (Chen & Guestrin, 2016), and generative approaches (Vincent et al., 2008). Recent work has shifted toward deep learning techniques that model the distribution of node attributes. These include latent space models that align observed features with learned embeddings (Chen et al., 2020; Y oo et al., 2022), and GNN-based architectures designed to operate on incomplete inputs (Taguchi et al., 2021). These approaches, which rely on correlations in both feature and graph structure, are effective under moderate missing rates but experience significant performance degradation as sparsity increases, ultimately falling below simple baselines like zero-filling or mean imputation in highly incomplete settings(Y ou et al., 2020).

Explainable boosting machines (EBMs) are popular "glass-box" models that learn a set of univariate functions using boosting trees. These achieve explainability through visualizations of each feature's effect. However, unlike linear model coefficients, uncertainty quantification for the learned univariate functions requires computationally intensive bootstrapping, making it hard to know which features truly matter. We provide an alternative using recent advances in statistical inference for gradient boosting, deriving methods for statistical inference as well as end-to-end theoretical guarantees. Using a moving average instead of a sum of trees (Boulevard regularization) allows the boosting process to converge to a feature-wise kernel ridge regression. This produces asymptotically normal predictions that achieve the minimax-optimal mean squared error for fitting Lipschitz GAMs with $p$ features at rate $O(pn^{-2/3})$, successfully avoiding the curse of dimensionality. We then construct prediction intervals for the response and confidence intervals for each learned univariate function with a runtime independent of the number of datapoints, enabling further explainability within EBMs.

In modern biomedical and econometric studies, longitudinal processes are often characterized by complex time-varying associations and abrupt regime shifts that are shared across correlated outcomes. Standard functional data analysis (FDA) methods, which prioritize smoothness, often fail to capture these dynamic structural features, particularly in high-dimensional settings. This article introduces Adaptive Joint Learning (AJL), a hierarchical regularization framework designed to integrate functional variable selection with structural changepoint detection in multivariate time-varying coefficient models. Unlike standard simultaneous estimation approaches, we propose a theoretically grounded two-stage screening-and-refinement procedure. This framework first synergizes adaptive group-wise penalization with sure screening principles to robustly identify active predictors, followed by a refined fused regularization step that effectively borrows strength across multiple outcomes to detect local regime shifts. We provide a rigorous theoretical analysis of the estimator in the ultra-high-dimensional regime (p >> n). Crucially, we establish the sure screening consistency of the first stage, which serves as the foundation for proving that the refined estimator achieves the oracle property-performing as well as if the true active set and changepoint locations were known a priori. A key theoretical contribution is the explicit handling of approximation bias via undersmoothing conditions to ensure valid asymptotic inference. The proposed method is validated through comprehensive simulations and an application to Sleep-EDF data, revealing novel dynamic patterns in physiological states.

Empirical investigations into unintended model behavior often show that the algorithm is predicting another outcome than what was intended. These exposes highlight the need to identify when algorithms predict unintended quantities - ideally before deploying them into consequential settings. We propose a falsification framework that provides a principled statistical test for discriminant validity: the requirement that an algorithm predict intended outcomes better than impermissible ones. Drawing on falsification practices from causal inference, econometrics, and psychometrics, our framework compares calibrated prediction losses across outcomes to assess whether the algorithm exhibits discriminant validity with respect to a specified impermissible proxy. In settings where the target outcome is difficult to observe, multiple permissible proxy outcomes may be available; our framework accommodates both this setting and the case with a single permissible proxy. Throughout we use nonparametric hypothesis testing methods that make minimal assumptions on the data-generating process. We illustrate the method in an admissions setting, where the framework establishes discriminant validity with respect to gender but fails to establish discriminant validity with respect to race. This demonstrates how falsification can serve as an early validity check, prior to fairness or robustness analyses. We also provide analysis in a criminal justice setting, where we highlight the limitations of our framework and emphasize the need for complementary approaches to assess other aspects of construct validity and external validity.

Boosting has garnered significant interest across both machine learning and statistical communities. Traditional boosting algorithms, designed for fully observed random samples, often struggle with real-world problems, particularly with interval-censored data. This type of data is common in survival analysis and time-to-event studies where exact event times are unobserved but fall within known intervals. Effective handling of such data is crucial in fields like medical research, reliability engineering, and social sciences. In this work, we introduce novel nonparametric boosting methods for regression and classification tasks with interval-censored data. Our approaches leverage censoring unbiased transformations to adjust loss functions and impute transformed responses while maintaining model accuracy. Implemented via functional gradient descent, these methods ensure scalability and adaptability. We rigorously establish their theoretical properties, including optimality and mean squared error trade-offs. Our proposed methods not only offer a robust framework for enhancing predictive accuracy in domains where interval-censored data are common but also complement existing work, expanding the applicability of existing boosting techniques. Empirical studies demonstrate robust performance across various finite-sample scenarios, highlighting the practical utility of our approaches.