Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The hypothesis is that this representation captures essential information from the noisy EEG signal, improving disease detection. Statistical features extracted from this representation are utilised as input for interpretable machine learning models, specifically Decision Tree and AdaBoost classifiers. Our classification pipeline is deployed within our proposed framework which enables high-importance data types and brain regions for classification to be identified. Interestingly, our analysis reveals that while there is no significant regional importance, the N1 sleep data type exhibits statistically significant predictive power (p < 0.01) for early-stage Parkinson's Disease classification. AdaBoost classifiers trained on the N1 data type consistently outperform baseline models, achieving over 80% accuracy and recall. Our classification pipeline statistically significantly outperforms baseline models indicating that the model has acquired useful information. Paired with the interpretability (ability to view feature importance's) of our pipeline this enables us to generate meaningful insights into the classification of early stage Parkinson's with our N1 models. In Future, these models could be deployed in the real world - the results presented in this paper indicate that more than 3 in 4 early-stage Parkinson's cases would be captured with our pipeline.

Estimating the prevalence of a medical condition, or the proportion of the population in which it occurs, is a fundamental problem in healthcare and public health. Accurate estimates of the relative prevalence across groups -- capturing, for example, that a condition affects women more frequently than men -- facilitate effective and equitable health policy which prioritizes groups who are disproportionately affected by a condition. However, it is difficult to estimate relative prevalence when a medical condition is underreported. In this work, we provide a method for accurately estimating the relative prevalence of underreported medical conditions, building upon the positive unlabeled learning framework. We show that under the commonly made covariate shift assumption -- i.e., that the probability of having a disease conditional on symptoms remains constant across groups -- we can recover the relative prevalence, even without restrictive assumptions commonly made in positive unlabeled learning and even if it is impossible to recover the absolute prevalence. We conduct experiments on synthetic and real health data which demonstrate our method's ability to recover the relative prevalence more accurately than do baselines, and demonstrate the method's robustness to plausible violations of the covariate shift assumption. We conclude by illustrating the applicability of our method to case studies of intimate partner violence and hate speech.

Supervised imitation learning, also known as behavioral cloning, suffers from distribution drift leading to failures during policy execution. One approach to mitigate this issue is to allow an expert to correct the agent's actions during task execution, based on the expert's determination that the agent has reached a `point of no return.' The agent's policy is then retrained using this new corrective data. This approach alone can enable high-performance agents to be learned, but at a substantial cost: the expert must vigilantly observe execution until the policy reaches a specified level of success, and even at that point, there is no guarantee that the policy will always succeed. To address these limitations, we present FIRE (Failure Identification to Reduce Expert Burden in intervention-based learning), a system that can predict when a running policy will fail, halt its execution, and request a correction from the expert. Unlike existing approaches that learn only from expert data, our approach learns from both expert and non-expert data, akin to adversarial learning. We demonstrate experimentally for a series of challenging manipulation tasks that our method is able to recognize state-action pairs that lead to failures. This permits seamless integration into an intervention-based learning system, where we show an order-of-magnitude gain in sample efficiency compared with a state-of-the-art inverse reinforcement learning method and dramatically improved performance over an equivalent amount of data learned with behavioral cloning.

Multi-source domain adaptation (DA) aims at leveraging information from more than one source domain to make predictions in a target domain, where different domains may have different data distributions. Most existing methods for multi-source DA focus on classification problems while there is only limited investigation in the regression settings. In this paper, we fill in this gap through a two-step procedure. First, we extend a flexible single-source DA algorithm for classification through outcome-coarsening to enable its application to regression problems. We then augment our single-source DA algorithm for regression with ensemble learning to achieve multi-source DA. We consider three learning paradigms in the ensemble algorithm, which combines linearly the target-adapted learners trained with each source domain: (i) a multi-source stacking algorithm to obtain the ensemble weights; (ii) a similarity-based weighting where the weights reflect the quality of DA of each target-adapted learner; and (iii) a combination of the stacking and similarity weights. We illustrate the performance of our algorithms with simulations and a data application where the goal is to predict High-density lipoprotein (HDL) cholesterol levels using gut microbiome. We observe a consistent improvement in prediction performance of our multi-source DA algorithm over the routinely used methods in all these scenarios.

The is no other model or hypothesis verification tool in Bayesian statistics that is as widely used as the Bayes factor. We focus on generative models that are likelihood-free and, therefore, render the computation of Bayes factors (marginal likelihood ratios) far from obvious. We propose a deep learning estimator of the Bayes factor based on simulated data from two competing models using the likelihood ratio trick. This estimator is devoid of summary statistics and obviates some of the difficulties with ABC model choice. We establish sufficient conditions for consistency of our Deep Bayes Factor estimator as well as its consistency as a model selection tool. We investigate the performance of our estimator on various examples using a wide range of quality metrics related to estimation and model decision accuracy. After training, our deep learning approach enables rapid evaluations of the Bayes factor estimator at any fictional data arriving from either hypothesized model, not just the observed data $Y_0$. This allows us to inspect entire Bayes factor distributions under the two models and to quantify the relative location of the Bayes factor evaluated at $Y_0$ in light of these distributions. Such tail area evaluations are not possible for Bayes factor estimators tailored to $Y_0$. We find the performance of our Deep Bayes Factors competitive with existing MCMC techniques that require the knowledge of the likelihood function. We also consider variants for posterior or intrinsic Bayes factors estimation. We demonstrate the usefulness of our approach on a relatively high-dimensional real data example about determining cognitive biases.

This paper investigates new families of compositional optimization problems, called non-smooth weakly-convex finite-sum coupled compositional optimization (NSWC FCCO). There has been a growing interest in FCCO due to its wide-ranging applications in machine learning and AI, as well as its ability to address the shortcomings of stochastic algorithms based on empirical risk minimization. However, current research on FCCO presumes that both the inner and outer functions are smooth, limiting their potential to tackle a more diverse set of problems. Our research expands on this area by examining non-smooth weakly-convex FCCO, where the outer function is weakly convex and non-decreasing, and the inner function is weakly-convex. We analyze a single-loop algorithm and establish its complexity for finding an ϵ-stationary point of the Moreau envelop of the objective function. Additionally, we also extend the algorithm to solving novel non-smooth weakly-convex tri-level finite-sum coupled compositional optimization problems, which feature a nested arrangement of three functions. Lastly, we explore the applications of our algorithms in deep learning for two-way partial AUC maximization and multi-instance two-way partial AUC maximization, using empirical studies to showcase the effectiveness of the proposed algorithms.

Fox News Flash top sports headlines are here. Check out what's clicking on Foxnews.com. Alex Kane has been on a roll in the second half of the year with Major League Wrestling. The Georgia native became the MLW World Heavyweight Champion in July with a win over Alex Hammerstone at "Never Say Never" and has successfully defended the title three times since the victory with his faction – the Bomaye Fight Club – behind him. Thursday night will be one of Kane's toughest matches yet as he steps into the ring against the "Indy God" Matt Cardona at "One Shot" in New York City.

Recognising and reacting to change in non-stationary data-streams is a challenging task. The majority of research in this area assumes that the true class label of incoming points are available, either at each time step or intermittently with some latency. In the worse case this latency approaches infinity and we can assume that no labels are available beyond the initial training set. When change is expected and no further training labels are provided the challenge of maintaining a high classification accuracy is very great. The challenge is to propagate the original training information through several timesteps, possibly indefinitely, while adapting to underlying change in the data-stream. In this paper we conduct an initial study into the effectiveness of using an evolving, population-based approach as the mechanism for adapting to change. An ensemble of one-class-classifiers is maintained for each class. Each classifier is considered as an agent in the sub-population and is subject to selection pressure to find interesting areas of the feature space. This selection pressure forces the ensemble to adapt to the underlying change in the data-stream.

The prevalence of online content has led to the widespread adoption of recommendation systems (RSs), which serve diverse purposes such as news, advertisements, and e-commerce recommendations. Despite their significance, data scarcity issues have significantly impaired the effectiveness of existing RS models and hindered their progress. To address this challenge, the concept of knowledge transfer, particularly from external sources like pre-trained language models, emerges as a potential solution to alleviate data scarcity and enhance RS development. However, the practice of knowledge transfer in RSs is intricate. Transferring knowledge between domains introduces data disparities, and the application of knowledge transfer in complex RS scenarios can yield negative consequences if not carefully designed. Therefore, this article contributes to this discourse by addressing the implications of data scarcity on RSs and introducing various strategies, such as data augmentation, self-supervised learning, transfer learning, broad learning, and knowledge graph utilization, to mitigate this challenge. Furthermore, it delves into the challenges and future direction within the RS domain, offering insights that are poised to facilitate the development and implementation of robust RSs, particularly when confronted with data scarcity. We aim to provide valuable guidance and inspiration for researchers and practitioners, ultimately driving advancements in the field of RS.

In fairness audits, a standard objective is to detect whether a given algorithm performs substantially differently between subgroups. Properly powering the statistical analysis of such audits is crucial for obtaining informative fairness assessments, as it ensures a high probability of detecting unfairness when it exists. However, limited guidance is available on the amount of data necessary for a fairness audit, lacking directly applicable results concerning commonly used fairness metrics. Additionally, the consideration of unequal subgroup sample sizes is also missing. In this tutorial, we address these issues by providing guidance on how to determine the required subgroup sample sizes to maximize the statistical power of hypothesis tests for detecting unfairness. Our findings are applicable to audits of binary classification models and multiple fairness metrics derived as summaries of the confusion matrix. Furthermore, we discuss other aspects of audit study designs that can increase the reliability of audit results.