Recent research has generated hope that inference scaling could allow weaker language models to match or exceed the accuracy of stronger models, such as by repeatedly sampling solutions to a coding problem until it passes unit tests. The central thesis of this paper is that there is no free lunch for inference scaling: indefinite accuracy improvement through resampling can only be realized if the "verifier" (in this case, a set of unit tests) is perfect. When the verifier is imperfect, as it almost always is in domains such as reasoning or coding (for example, unit tests have imperfect coverage), there is a nonzero probability of false positives: incorrect solutions that pass the verifier. Resampling cannot decrease this probability, so it imposes an upper bound to the accuracy of resampling-based inference scaling even with an infinite compute budget. We find that there is a very strong correlation between the model's single-sample accuracy (i.e. accuracy without unit tests) and its false positive rate on coding benchmarks HumanEval and MBPP, whose unit tests have limited coverage. Therefore, no amount of inference scaling of weaker models can enable them to match the single-sample accuracy of a sufficiently strong model (Fig. 1a). When we consider that false positives have a negative utility compared to abstaining from producing a solution, it bends the inference scaling curve further downward. Empirically, we find that the optimal number of samples can be less than 10 under realistic assumptions (Fig. 1b). Finally, we show that beyond accuracy, false positives may have other undesirable qualities, such as poor adherence to coding style conventions.

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for diagnostic purposes; however, they are now recognized for their potential in molecular profiling, which provides deeper insights into cancer prognosis and treatment response. Recent advancements in artificial intelligence (AI) have enabled digital pathology to analyze histopathologic images for both targeted molecular and broader omic biomarkers, marking a pivotal step in personalized cancer care. These technologies offer the capability to extract various biomarkers such as genomic, transcriptomic, proteomic, and metabolomic markers directly from the routine hematoxylin and eosin (H&E) stained images, which can support treatment decisions without the need for costly molecular assays. In this work, we provide a comprehensive review of AI-driven techniques for biomarker detection, with a focus on diverse omic biomarkers that allow novel biomarker discovery. Additionally, we analyze the major challenges faced in this field for robust algorithm development. These challenges highlight areas where further research is essential to bridge the gap between AI research and clinical application.

While Transformers have revolutionized machine learning on various data, existing Transformers for temporal graphs face limitations in (1) restricted receptive fields, (2) overhead of subgraph extraction, and (3) suboptimal generalization capability beyond link prediction. In this paper, we rethink temporal graph Transformers and propose TGTOD, a novel end-to-end Temporal Graph Transformer for Outlier Detection. TGTOD employs global attention to model both structural and temporal dependencies within temporal graphs. To tackle scalability, our approach divides large temporal graphs into spatiotemporal patches, which are then processed by a hierarchical Transformer architecture comprising Patch Transformer, Cluster Transformer, and Temporal Transformer. We evaluate TGTOD on three public datasets under two settings, comparing with a wide range of baselines. Our experimental results demonstrate the effectiveness of TGTOD, achieving AP improvement of 61% on Elliptic. Furthermore, our efficiency evaluation shows that TGTOD reduces training time by 44x compared to existing Transformers for temporal graphs. To foster reproducibility, we make our implementation publicly available at https://github.com/kayzliu/tgtod.

In many applications it is important that a classification model not only has high accuracy but that a user is also provided with a reliable estimate of confidence in the predicted label. Calibration is a concept that is often invoked to provide such confidence estimates to a user. As such, calibration is a notion that is inherently aimed at human interpretation. In binary classification, a perfectly calibrated model f provides the guarantee that if it predicts fpxq " p on some instance x, then among the set of all instances on which f assigns this value p the probability of label 1 is indeed p (and the probability of label 0 thus 1 p). While calibration is generally considered useful, we would argue that in many cases, even if achieved, it is doomed to fail at its original goal of providing insight to a human user: for most suitably complex classification models, a human user that observes fpxq " p has no notion of the set of all instances on which f also outputs p.

As the ubiquity of smart mobile devices continues to rise, Optical Camera Communication systems have gained more attention as a solution for efficient and private data streaming. This system utilizes optical cameras to receive data from digital screens via visible light. Despite their promise, most of them are hindered by dynamic factors such as screen refreshing and rapid camera motion. CMOS cameras, often serving as the receivers, suffer from limited frame rates and motion-induced image blur, which degrade overall performance. To address these challenges, this paper unveils a novel system that utilizes event cameras. We introduce a dynamic visual marker and design event-based tracking algorithms to achieve fast localization and data streaming. Remarkably, the event camera's unique capabilities mitigate issues related to screen refresh rates and camera motion, enabling a high throughput of up to 114 Kbps in static conditions, and a 1 cm localization accuracy with 1% bit error rate under various camera motions.

As opaque black-box predictive models become more prevalent, the need to develop interpretations for these models is of great interest. The concept of variable importance and Shapley values are interpretability measures that applies to any predictive model and assesses how much a variable or set of variables improves prediction performance. When the number of variables is large, estimating variable importance presents a significant computational challenge because re-training neural networks or other black-box algorithms requires significant additional computation. In this paper, we address this challenge for algorithms using gradient descent and gradient boosting (e.g. neural networks, gradient-boosted decision trees). By using the ideas of early stopping of gradient-based methods in combination with warm-start using the dropout method, we develop a scalable method to estimate variable importance for any algorithm that can be expressed as an iterative kernel update equation. Importantly, we provide theoretical guarantees by using the theory for early stopping of kernel-based methods for neural networks with sufficiently large (but not necessarily infinite) width and gradient-boosting decision trees that use symmetric trees as a weaker learner. We also demonstrate the efficacy of our methods through simulations and a real data example which illustrates the computational benefit of early stopping rather than fully re-training the model as well as the increased accuracy of our approach.

The aim of this paper is to formalise the task of continual semi-supervised anomaly detection (CSAD), with the aim of highlighting the importance of such a problem formulation which assumes as close to real-world conditions as possible. After an overview of the relevant definitions of continual semi-supervised learning, its components, anomaly detection extension, and the training protocols; the paper introduces a baseline model of a variational autoencoder (VAE) to work with semi-supervised data along with a continual learning method of deep generative replay with outlier rejection. The results show that such a use of extreme value theory (EVT) applied to anomaly detection can provide promising results even in comparison to an upper baseline of joint training. The results explore the effects of how much labelled and unlabelled data is present, of which class, and where it is located in the data stream. Outlier rejection shows promising initial results where it often surpasses a baseline method of Elastic Weight Consolidation (EWC). A baseline for CSAD is put forward along with the specific dataset setups used for reproducability and testability for other practitioners. Future research directions include other CSAD settings and further research into efficient continual hyperparameter tuning.

Overfitting has long been stigmatized as detrimental to model performance, especially in the context of anomaly detection. Our work challenges this conventional view by introducing a paradigm shift, recasting overfitting as a controllable and strategic mechanism for enhancing model discrimination capabilities. In this paper, we present Controllable Overfitting-based Anomaly Detection (COAD), a novel framework designed to leverage overfitting for optimized anomaly detection. We propose the Aberrance Retention Quotient (ARQ), a novel metric that systematically quantifies the extent of overfitting, enabling the identification of an optimal "golden overfitting interval." Within this interval, overfitting is leveraged to significantly amplify the model's sensitivity to anomalous patterns, while preserving generalization to normal samples. Additionally, we present the Relative Anomaly Distribution Index (RADI), an innovative metric designed to complement AUROC pixel by providing a more versatile and theoretically robust framework for assessing model performance. RADI leverages ARQ to track and evaluate how overfitting impacts anomaly detection, offering an integrated approach to understanding the relationship between overfitting dynamics and model efficacy. Our theoretical work also rigorously validates the use of Gaussian noise in pseudo anomaly synthesis, providing the foundation for its broader applicability across diverse domains. Empirical evaluations demonstrate that our controllable overfitting method not only achieves State of the Art (SOTA) performance in both one-class and multi-class anomaly detection tasks but also redefines overfitting from a modeling challenge into a powerful tool for optimizing anomaly detection.

Sarcasm is hard to interpret as human beings. Being able to interpret sarcasm is often termed as a sign of intelligence, given the complex nature of sarcasm. Hence, this is a field of Natural Language Processing which is still complex for computers to decipher. This Literature Survey delves into different aspects of sarcasm detection, to create an understanding of the underlying problems faced during detection, approaches used to solve this problem, and different forms of available datasets for sarcasm detection.

This paper presents the system description of our entry for the COLING 2025 FMD challenge, focusing on misinformation detection in financial domains. We experimented with a combination of large language models, including Qwen, Mistral, and Gemma-2, and leveraged pre-processing and sequential learning for not only identifying fraudulent financial content but also generating coherent, and concise explanations that clarify the rationale behind the classifications. Our approach achieved competitive results with an F1-score of 0.8283 for classification, and ROUGE-1 of 0.7253 for explanations. This work highlights the transformative potential of LLMs in financial applications, offering insights into their capabilities for combating misinformation and enhancing transparency while identifying areas for future improvement in robustness and domain adaptation.