Crohn's disease and intestinal tuberculosis share many overlapping features such as clinical, radiological, endoscopic, and histological features - particularly granulomas, making it challenging to clinically differentiate them. Our research leverages 3D CTE scans, computer vision, and machine learning to improve this differentiation to avoid harmful treatment mismanagement such as unnecessary anti-tuberculosis therapy for Crohn's disease or exacerbation of tuberculosis with immunosuppressants. Our study proposes a novel method to identify radiologist - identified biomarkers such as VF to SF ratio, necrosis, calcifications, comb sign and pulmonary TB to enhance accuracy. We demonstrate the effectiveness by using different ML techniques on the features extracted from these biomarkers, computing SHAP on XGBoost for understanding feature importance towards predictions, and comparing against SOTA methods such as pretrained ResNet and CTFoundation.

Neural posterior estimation (NPE), a type of amortized variational inference, is a computationally efficient means of constructing probabilistic catalogs of light sources from astronomical images. To date, NPE has not been used to perform inference in models with spatially varying covariates. However, ground-based astronomical images have spatially varying sky backgrounds and point spread functions (PSFs), and accounting for this variation is essential for constructing accurate catalogs of imaged light sources. In this work, we introduce a method of performing NPE with spatially varying backgrounds and PSFs. In this method, we generate synthetic catalogs and semi-synthetic images for these catalogs using randomly sampled PSF and background estimates from existing surveys. Using this data, we train a neural network, which takes an astronomical image and representations of its background and PSF as input, to output a probabilistic catalog. Our experiments with Sloan Digital Sky Survey data demonstrate the effectiveness of NPE in the presence of spatially varying backgrounds and PSFs for light source detection, star/galaxy separation, and flux measurement.

Recent years have witnessed a surge in the development of protein structural tokenization methods, which chunk protein 3D structures into discrete or continuous representations. Structure tokenization enables the direct application of powerful techniques like language modeling for protein structures, and large multimodal models to integrate structures with protein sequences and functional texts. Despite the progress, the capabilities and limitations of these methods remain poorly understood due to the lack of a unified evaluation framework. We first introduce StructTokenBench, a framework that comprehensively evaluates the quality and efficiency of structure tokenizers, focusing on fine-grained local substructures rather than global structures, as typical in existing benchmarks. Our evaluations reveal that no single model dominates all benchmarking perspectives. Observations of codebook under-utilization led us to develop AminoAseed, a simple yet effective strategy that enhances codebook gradient updates and optimally balances codebook size and dimension for improved tokenizer utilization and quality. Compared to the leading model ESM3, our method achieves an average of 6.31% performance improvement across 24 supervised tasks, with sensitivity and utilization rates increased by 12.83% and 124.03%, respectively.

Zero-Touch Networks (ZTNs) represent a state-of-the-art paradigm shift towards fully automated and intelligent network management, enabling the automation and intelligence required to manage the complexity, scale, and dynamic nature of next-generation (6G) networks. ZTNs leverage Artificial Intelligence (AI) and Machine Learning (ML) to enhance operational efficiency, support intelligent decision-making, and ensure effective resource allocation. However, the implementation of ZTNs is subject to security challenges that need to be resolved to achieve their full potential. In particular, two critical challenges arise: the need for human expertise in developing AI/ML-based security mechanisms, and the threat of adversarial attacks targeting AI/ML models. In this survey paper, we provide a comprehensive review of current security issues in ZTNs, emphasizing the need for advanced AI/ML-based security mechanisms that require minimal human intervention and protect AI/ML models themselves. Furthermore, we explore the potential of Automated ML (AutoML) technologies in developing robust security solutions for ZTNs. Through case studies, we illustrate practical approaches to securing ZTNs against both conventional and AI/ML-specific threats, including the development of autonomous intrusion detection systems and strategies to combat Adversarial ML (AML) attacks. The paper concludes with a discussion of the future research directions for the development of ZTN security approaches.

Localizing humans is a key prerequisite for any service robot operating in proximity to people. In these scenarios, robots rely on a multitude of state-of-the-art detectors usually designed to operate with RGB-D cameras or expensive 3D LiDARs. However, most commercially available service robots are equipped with cameras with a narrow field of view, making them blind when a user is approaching from other directions, or inexpensive 1D LiDARs whose readings are difficult to interpret. To address these limitations, we propose a self-supervised approach to detect humans and estimate their 2D pose from 1D LiDAR data, using detections from an RGB-D camera as a supervision source. Our approach aims to provide service robots with spatial awareness of nearby humans. After training on 70 minutes of data autonomously collected in two environments, our model is capable of detecting humans omnidirectionally from 1D LiDAR data in a novel environment, with 71% precision and 80% recall, while retaining an average absolute error of 13 cm in distance and 44{\deg} in orientation.

Open-world continual learning (OWCL) adapts to sequential tasks with open samples, learning knowledge incrementally while preventing forgetting. However, existing OWCL still requires a large amount of labeled data for training, which is often impractical in real-world applications. Given that new categories/entities typically come with limited annotations and are in small quantities, a more realistic situation is OWCL with scarce labeled data, i.e., few-shot training samples. Hence, this paper investigates the problem of open-world few-shot continual learning (OFCL), challenging in (i) learning unbounded tasks without forgetting previous knowledge and avoiding overfitting, (ii) constructing compact decision boundaries for open detection with limited labeled data, and (iii) transferring knowledge about knowns and unknowns and even update the unknowns to knowns once the labels of open samples are learned. In response, we propose a novel OFCL framework that integrates three key components: (1) an instance-wise token augmentation (ITA) that represents and enriches sample representations with additional knowledge, (2) a margin-based open boundary (MOB) that supports open detection with new tasks emerge over time, and (3) an adaptive knowledge space (AKS) that endows unknowns with knowledge for the updating from unknowns to knowns. Finally, extensive experiments show the proposed OFCL framework outperforms all baselines remarkably with practical importance and reproducibility. The source code is released at https://github.com/liyj1201/OFCL.

Differentially Private Stochastic Gradient Descent (DPSGD) is widely used to protect sensitive data during the training of machine learning models, but its privacy guarantees often come at the cost of model performance, largely due to the inherent challenge of accurately quantifying privacy loss. While recent efforts have strengthened privacy guarantees by focusing solely on the final output and bounded domain cases, they still impose restrictive assumptions, such as convexity and other parameter limitations, and often lack a thorough analysis of utility. In this paper, we provide rigorous privacy and utility characterization for DPSGD for smooth loss functions in both bounded and unbounded domains. We track the privacy loss over multiple iterations by exploiting the noisy smooth-reduction property and establish the utility analysis by leveraging the projection's non-expansiveness and clipped SGD properties. In particular, we show that for DPSGD with a bounded domain, (i) the privacy loss can still converge without the convexity assumption, and (ii) a smaller bounded diameter can improve both privacy and utility simultaneously under certain conditions. Numerical results validate our results.

To maximize palm oil yield and quality, it is essential to harvest palm fruit at the optimal maturity stage. This project aims to develop an automated computer vision system capable of accurately classifying palm fruit images into five ripeness levels. We employ deep Convolutional Neural Networks (CNNs) to classify palm fruit images based on their maturity stage. A shallow CNN serves as the baseline model, while transfer learning and fine-tuning are applied to pre-trained ResNet50 and InceptionV3 architectures. The study utilizes a publicly available dataset of over 8,000 images with significant variations, which is split into 80\% for training and 20\% for testing. The proposed deep CNN models achieve test accuracies exceeding 85\% in classifying palm fruit maturity stages. This research highlights the potential of deep learning for automating palm fruit ripeness assessment, which can contribute to optimizing harvesting decisions and improving palm oil production efficiency.

In self-supervised contrastive learning, negative pairs are typically constructed using an anchor image and a sample drawn from the entire dataset, excluding the anchor. However, this approach can result in the creation of negative pairs with similar semantics, referred to as "false negatives", leading to their embeddings being falsely pushed apart. To address this issue, we introduce GloFND, an optimization-based approach that automatically learns on the fly the threshold for each anchor data to identify its false negatives during training. In contrast to previous methods for false negative discovery, our approach globally detects false negatives across the entire dataset rather than locally within the mini-batch. Moreover, its per-iteration computation cost remains independent of the dataset size. Experimental results on image and image-text data demonstrate the effectiveness of the proposed method. Our implementation is available at https://github.com/vibalcam/GloFND .

The transition from 5G to 6G mobile networks necessitates network automation to meet the escalating demands for high data rates, ultra-low latency, and integrated technology. Recently, Zero-Touch Networks (ZTNs), driven by Artificial Intelligence (AI) and Machine Learning (ML), are designed to automate the entire lifecycle of network operations with minimal human intervention, presenting a promising solution for enhancing automation in 5G/6G networks. However, the implementation of ZTNs brings forth the need for autonomous and robust cybersecurity solutions, as ZTNs rely heavily on automation. AI/ML algorithms are widely used to develop cybersecurity mechanisms, but require substantial specialized expertise and encounter model drift issues, posing significant challenges in developing autonomous cybersecurity measures. Therefore, this paper proposes an automated security framework targeting Physical Layer Authentication (PLA) and Cross-Layer Intrusion Detection Systems (CLIDS) to address security concerns at multiple Internet protocol layers. The proposed framework employs drift-adaptive online learning techniques and a novel enhanced Successive Halving (SH)-based Automated ML (AutoML) method to automatically generate optimized ML models for dynamic networking environments. Experimental results illustrate that the proposed framework achieves high performance on the public Radio Frequency (RF) fingerprinting and the Canadian Institute for CICIDS2017 datasets, showcasing its effectiveness in addressing PLA and CLIDS tasks within dynamic and complex networking environments. Furthermore, the paper explores open challenges and research directions in the 5G/6G cybersecurity domain. This framework represents a significant advancement towards fully autonomous and secure 6G networks, paving the way for future innovations in network automation and cybersecurity.