Accuracy
Critical appraisal of artificial intelligence for rare-event recognition: principles and pharmacovigilance case studies
Noren, G. Niklas, Meldau, Eva-Lisa, Ellenius, Johan
Many high-stakes AI applications target low-prevalence events, where apparent accuracy can conceal limited real-world value. Relevant AI models range from expert-defined rules and traditional machine learning to generative LLMs constrained for classification. We outline key considerations for critical appraisal of AI in rare-event recognition, including problem framing and test set design, prevalence-aware statistical evaluation, robustness assessment, and integration into human workflows. In addition, we propose an approach to structured case-level examination (SCLE), to complement statistical performance evaluation, and a comprehensive checklist to guide procurement or development of AI models for rare-event recognition. We instantiate the framework in pharmacovigilance, drawing on three studies: rule-based retrieval of pregnancy-related reports; duplicate detection combining machine learning with probabilistic record linkage; and automated redaction of person names using an LLM. We highlight pitfalls specific to the rare-event setting including optimism from unrealistic class balance and lack of difficult positive controls in test sets - and show how cost-sensitive targets align model performance with operational value. While grounded in pharmacovigilance practice, the principles generalize to domains where positives are scarce and error costs may be asymmetric.
Diffusion-Assisted Distillation for Self-Supervised Graph Representation Learning with MLPs
Ahn, Seong Jin, Kim, Myoung-Ho
Abstract--For large-scale applications, there is growing interest in replacing Graph Neural Networks (GNNs) with lightweight Multi-Layer Perceptrons (MLPs) via knowledge distillation. However, distilling GNNs for self-supervised graph representation learning into MLPs is more challenging. This is because the performance of self-supervised learning is more related to the model's inductive bias than supervised learning. This motivates us to design a new distillation method to bridge a huge capacity gap between GNNs and MLPs in self-supervised graph representation learning. In this paper, we propose Diffusion-Assisted Distillation for Self-supervised Graph representation learning with MLPs (DAD-SGM). The proposed method employs a denoising diffusion model as a teacher assistant to better distill the knowledge from the teacher GNN into the student MLP . This approach enhances the generalizability and robustness of MLPs in self-supervised graph representation learning. Extensive experiments demonstrate that DAD-SGM effectively distills the knowledge of self-supervised GNNs compared to state-of-the-art GNN-to-MLP distillation methods. Impact Statement--This paper presents Diffusion-Assisted Distillation for Self-supervised Graph representation learning with MLPs (DAD-SGM), a novel framework that addresses the performance gap between GNNs and MLPs in self-supervised graph learning. Our approach first trains an assistant denoising diffusion model that learns to predict noise from noisy outputs of the GNN teacher .
Moral Anchor System: A Predictive Framework for AI Value Alignment and Drift Prevention
The rise of artificial intelligence (AI) as super-capable assistants has transformed productivity and decision-making across domains. Yet, this integration raises critical concerns about value alignment - ensuring AI behaviors remain consistent with human ethics and intentions. A key risk is value drift, where AI systems deviate from aligned values due to evolving contexts, learning dynamics, or unintended optimizations, potentially leading to inefficiencies or ethical breaches. We propose the Moral Anchor System (MAS), a novel framework to detect, predict, and mitigate value drift in AI agents. MAS combines real-time Bayesian inference for monitoring value states, LSTM networks for forecasting drift, and a human-centric governance layer for adaptive interventions. It emphasizes low-latency responses (<20 ms) to prevent breaches, while reducing false positives and alert fatigue via supervised fine-tuning with human feedback. Our hypothesis: integrating probabilistic drift detection, predictive analytics, and adaptive governance can reduce value drift incidents by 80 percent or more in simulations, maintaining high detection accuracy (85 percent) and low false positive rates (0.08 post-adaptation). Rigorous experiments with goal-misaligned agents validate MAS's scalability and responsiveness. MAS's originality lies in its predictive and adaptive nature, contrasting static alignment methods. Contributions include: (1) MAS architecture for AI integration; (2) empirical results prioritizing speed and usability; (3) cross-domain applicability insights; and (4) open-source code for replication.
Adaptive kernel-density approach for imbalanced binary classification
Nishimura, Kotaro J., Sakumura, Yuichi, Ikeda, Kazushi
Abstract--Class imbalance is a common challenge in real-world binary classification tasks, often leading to predictions biased toward the majority class and reduced recognition of the minority class. This issue is particularly critical in domains such as medical diagnosis and anomaly detection, where correct classification of minority classes is essential. Conventional methods often fail to deliver satisfactory performance when the imbalance ratio is extremely severe. T o address this challenge, we propose a novel approach called Kernel-density-Oriented Threshold Adjustment with Regional Optimization (KOT ARO), which extends the framework of kernel density estimation (KDE) by adaptively adjusting decision boundaries according to local sample density. In KOT ARO, the bandwidth of Gaussian basis functions is dynamically tuned based on the estimated density around each sample, thereby enhancing the classifier's ability to capture minority regions. The results demonstrated that KOT ARO outperformed conventional methods, particularly under conditions of severe imbalance, highlighting its potential as a promising solution for a wide range of imbalanced classification problems. In real-world binary classification tasks, class imbalance is a common and challenging issue, where one class significantly outnumbers the other.
Thai Semantic End-of-Turn Detection for Real-Time Voice Agents
Popit, Thanapol, Rungseesiripak, Natthapath, Charattrakool, Monthol, Ruangtanusak, Saksorn
Fluid voice-to-voice interaction requires reliable and low-latency detection of when a user has finished speaking. Traditional audio-silence end-pointers add hundreds of milliseconds of delay and fail under hesitations or language-specific phenomena. We present, to our knowledge, the first systematic study of Thai text-only end-of-turn (EOT) detection for real-time agents. We compare zero-shot and few-shot prompting of compact LLMs to supervised fine-tuning of lightweight transformers. Using transcribed subtitles from the YODAS corpus and Thai-specific linguistic cues (e.g., sentence-final particles), we formulate EOT as a binary decision over token boundaries. We report a clear accuracy-latency tradeoff and provide a public-ready implementation plan. This work establishes a Thai baseline and demonstrates that small, fine-tuned models can deliver near-instant EOT decisions suitable for on-device agents.
Optimizing Resources for On-the-Fly Label Estimation with Multiple Unknown Medical Experts
Bary, Tim, Godelaine, Tiffanie, Abels, Axel, Macq, Benoรฎt
Accurate ground truth estimation in medical screening programs often relies on coalitions of experts and peer second opinions. Algorithms that efficiently aggregate noisy annotations can enhance screening workflows, particularly when data arrive continuously and expert proficiency is initially unknown. However, existing algorithms do not meet the requirements for seamless integration into screening pipelines. We therefore propose an adaptive approach for real-time annotation that (I) supports on-the-fly labeling of incoming data, (II) operates without prior knowledge of medical experts or pre-labeled data, and (III) dynamically queries additional experts based on the latent difficulty of each instance. The method incrementally gathers expert opinions until a confidence threshold is met, providing accurate labels with reduced annotation overhead. We evaluate our approach on three multi-annotator classification datasets across different modalities. Results show that our adaptive querying strategy reduces the number of expert queries by up to 50% while achieving accuracy comparable to a non-adaptive baseline. Our code is available at https://github.com/tbary/MEDICS
On the Empirical Power of Goodness-of-Fit Tests in Watermark Detection
He, Weiqing, Li, Xiang, Shang, Tianqi, Shen, Li, Su, Weijie, Long, Qi
Large language models (LLMs) raise concerns about content authenticity and integrity because they can generate human-like text at scale. Text watermarks, which embed detectable statistical signals into generated text, offer a provable way to verify content origin. Many detection methods rely on pivotal statistics that are i.i.d. under human-written text, making goodness-of-fit (GoF) tests a natural tool for watermark detection. However, GoF tests remain largely underexplored in this setting. In this paper, we systematically evaluate eight GoF tests across three popular watermarking schemes, using three open-source LLMs, two datasets, various generation temperatures, and multiple post-editing methods. We find that general GoF tests can improve both the detection power and robustness of watermark detectors. Notably, we observe that text repetition, common in low-temperature settings, gives GoF tests a unique advantage not exploited by existing methods. Our results highlight that classic GoF tests are a simple yet powerful and underused tool for watermark detection in LLMs.
WAFFLE: A Wearable Approach to Bite Timing Estimation in Robot-Assisted Feeding
Padmanabha, Akhil, Yuan, Jessie, Mehta, Tanisha, Jenamani, Rajat Kumar, Hu, Eric, de Leรณn, Victoria, Wertz, Anthony, Gupta, Janavi, Dodson, Ben, Yan, Yunting, Majidi, Carmel, Bhattacharjee, Tapomayukh, Erickson, Zackory
Millions of people around the world need assistance with feeding. Robotic feeding systems offer the potential to enhance autonomy and quality of life for individuals with impairments and reduce caregiver workload. However, their widespread adoption has been limited by technical challenges such as estimating bite timing, the appropriate moment for the robot to transfer food to a user's mouth. In this work, we introduce WAFFLE: Wearable Approach For Feeding with LEarned bite timing, a system that accurately predicts bite timing by leveraging wearable sensor data to be highly reactive to natural user cues such as head movements, chewing, and talking. We train a supervised regression model on bite timing data from 14 participants and incorporate a user-adjustable assertiveness threshold to convert predictions into proceed or stop commands. In a study with 15 participants without motor impairments with the Obi feeding robot, WAFFLE performs statistically on par with or better than baseline methods across measures of feeling of control, robot understanding, and workload, and is preferred by the majority of participants for both individual and social dining. We further demonstrate WAFFLE's generalizability in a study with 2 participants with motor impairments in their home environments using a Kinova 7DOF robot. Our findings support WAFFLE's effectiveness in enabling natural, reactive bite timing that generalizes across users, robot hardware, robot positioning, feeding trajectories, foods, and both individual and social dining contexts.
Adaptive and Explainable AI Agents for Anomaly Detection in Critical IoT Infrastructure using LLM-Enhanced Contextual Reasoning
Ensuring that critical IoT systems function safely and smoothly depends a lot on finding anomalies quickly. As more complex systems, like smart healthcare, energy grids and industrial automation, appear, it is easier to see the shortcomings of older methods of detection. Monitoring failures usually happen in dynamic, high dimensional situations, especially when data is incomplete, messy or always evolving. Such limits point out the requirement for adaptive, intelligent systems that always improve and think. LLMs are now capable of significantly changing how context is understood and semantic inference is done across all types of data. This proposal suggests using an LLM supported contextual reasoning method along with XAI agents to improve how anomalies are found in significant IoT environments. To discover hidden patterns and notice inconsistencies in data streams, it uses attention methods, avoids dealing with details from every time step and uses memory buffers with meaning. Because no code AI stresses transparency and interpretability, people can check and accept the AI's decisions, helping ensure AI follows company policies. The two architectures are put together in a test that compares the results of the traditional model with those of the suggested LLM enhanced model. Important measures to check are the accuracy of detection, how much inaccurate information is included in the results, how clearly the findings can be read and how fast the system responds under different test situations. The metaheuristic is tested in simulations of real world smart grid and healthcare contexts to check its adaptability and reliability. From the study, we see that the new approach performs much better than most existing models in both accuracy and interpretation, so it could be a good fit for future anomaly detection tasks in IoT
Bridging the Gap Between Multimodal Foundation Models and World Models
Humans understand the world through the integration of multiple sensory modalities, enabling them to perceive, reason about, and imagine dynamic physical processes. Inspired by this capability, multimodal foundation models (MFMs) have emerged as powerful tools for multimodal understanding and generation. However, today's MFMs fall short of serving as effective world models. They lack the essential ability such as perform counterfactual reasoning, simulate dynamics, understand the spatiotemporal information, control generated visual outcomes, and perform multifaceted reasoning. We investigates what it takes to bridge the gap between multimodal foundation models and world models. We begin by improving the reasoning capabilities of MFMs through discriminative tasks and equipping MFMs with structured reasoning skills, such as causal inference, counterfactual thinking, and spatiotemporal reasoning, enabling them to go beyond surface correlations and understand deeper relationships within visual and textual data. Next, we explore generative capabilities of multimodal foundation models across both image and video modalities, introducing new frameworks for structured and controllable generation. Our approaches incorporate scene graphs, multimodal conditioning, and multimodal alignment strategies to guide the generation process, ensuring consistency with high-level semantics and fine-grained user intent. We further extend these techniques to controllable 4D generation, enabling interactive, editable, and morphable object synthesis over time and space.