Early detection of Alzheimer's Disease (AD) is greatly beneficial to AD patients, leading to early treatments that lessen symptoms and alleviating financial burden of health care. As one of the leading signs of AD, language capability changes can be used for early diagnosis of AD. In this paper, I develop a robust classification method using hybrid word embedding and fine-tuned hyperparameters to achieve state-of-the-art accuracy in the early detection of AD. Specifically, we create a hybrid word embedding based on word vectors from Doc2Vec and ELMo to obtain perplexity scores of the sentences. The scores identify whether a sentence is fluent or not and capture semantic context of the sentences. I enrich the word embedding by adding linguistic features to analyze syntax and semantics. Further, we input an embedded feature vector into logistic regression and fine tune hyperparameters throughout the pipeline. By tuning hyperparameters of the machine learning pipeline (e.g., model regularization parameter, learning rate and vector size of Doc2Vec, and vector size of ELMo), I achieve 91% classification accuracy and an Area Under the Curve (AUC) of 97% in distinguishing early AD from healthy subjects. Based on my knowledge, my model with 91% accuracy and 97% AUC outperforms the best existing NLP model for AD diagnosis with an accuracy of 88% [32]. I study the model stability through repeated experiments and find that the model is stable even though the training data is split randomly (standard deviation of accuracy = 0.0403; standard deviation of AUC = 0.0174). This affirms our proposed method is accurate and stable. This model can be used as a large-scale screening method for AD, as well as a complementary examination for doctors to detect AD.

Retrieval plays a central role in multi-hop question answering (QA), where answering complex questions requires gathering multiple pieces of evidence. We introduce an Agentic Retrieval System that leverages large language models (LLMs) in a structured loop to retrieve relevant evidence with high precision and recall. Our framework consists of three specialized agents: a Question Analyzer that decomposes a multi-hop question into sub-questions, a Selector that identifies the most relevant context for each sub-question (focusing on precision), and an Adder that brings in any missing evidence (focusing on recall). The iterative interaction between Selector and Adder yields a compact yet comprehensive set of supporting passages. In particular, it achieves higher retrieval accuracy while filtering out distracting content, enabling downstream QA models to surpass full-context answer accuracy while relying on significantly less irrelevant information. Experiments on four multi-hop QA benchmarks -- HotpotQA, 2WikiMultiHopQA, MuSiQue, and MultiHopRAG -- demonstrates that our approach consistently outperforms strong baselines.

As large language models (LLMs) become more capable and widely used, ensuring the safety of their outputs is increasingly critical. Existing guardrail models, though useful in static evaluation settings, face two major limitations in real-world applications: (1) they typically output only binary "safe/unsafe" labels, which can be interpreted inconsistently across diverse safety policies, rendering them incapable of accommodating varying safety tolerances across domains; and (2) they require complete model outputs before performing safety checks, making them fundamentally incompatible with streaming LLM inference, thereby preventing timely intervention during generation and increasing exposure to harmful partial outputs. To address these challenges, we present Qwen3Guard, a series of multilingual safety guardrail models with two specialized variants: Generative Qwen3Guard, which casts safety classification as an instruction-following task to enable fine-grained tri-class judgments (safe, controversial, unsafe); and Stream Qwen3Guard, which introduces a token-level classification head for real-time safety monitoring during incremental text generation. Both variants are available in three sizes (0.6B, 4B, and 8B parameters) and support up to 119 languages and dialects, providing comprehensive, scalable, and low-latency safety moderation for global LLM deployments. Evaluated across English, Chinese, and multilingual benchmarks, Qwen3Guard achieves state-of-the-art performance in both prompt and response safety classification. All models are released under the Apache 2.0 license for public use.

Understanding the spectral properties of kernels offers a principled perspective on generalization and representation quality. While deep models achieve state-of-the-art accuracy in molecular property prediction, kernel methods remain widely used for their robustness in low-data regimes and transparent theoretical grounding. Despite extensive studies of kernel spectra in machine learning, systematic spectral analyses of molecular kernels are scarce. In this work, we provide the first comprehensive spectral analysis of kernel ridge regression on the QM9 dataset, molecular fingerprint, pretrained transformer-based, global and local 3D representations across seven molecular properties. Surprisingly, richer spectral features, measured by four different spectral metrics, do not consistently improve accuracy. Pearson correlation tests further reveal that for transformer-based and local 3D representations, spectral richness can even have a negative correlation with performance. We also implement truncated kernels to probe the relationship between spectrum and predictive performance: in many kernels, retaining only the top 2% of eigenvalues recovers nearly all performance, indicating that the leading eigenvalues capture the most informative features. Our results challenge the common heuristic that "richer spectra yield better generalization" and highlight nuanced relationships between representation, kernel features, and predictive performance. Beyond molecular property prediction, these findings inform how kernel and self-supervised learning methods are evaluated in data-limited scientific and real-world tasks.

Artificial intelligence (AI) holds significant promise for enhancing intraoperative perception and decision-making in telesurgery, where physical separation impairs sensory feedback and control. Despite advances in medical AI and surgical robotics, conventional electronic AI architectures remain fundamentally constrained by the compounded latency from serial processing of inference and communication. This limitation is especially critical in latency-sensitive procedures such as endovascular interventions, where delays over 200 ms can compromise real-time AI reliability and patient safety. Here, we introduce an Optical Computation-in-Communication (OCiC) framework that reduces end-to-end latency significantly by performing AI inference concurrently with optical communication. OCiC integrates Optical Remote Computing Units (ORCUs) directly into the optical communication pathway, with each ORCU experimentally achieving up to 69 tera-operations per second per channel through spectrally efficient two-dimensional photonic convolution. The system maintains ultrahigh inference fidelity within 0.1% of CPU/GPU baselines on classification and coronary angiography segmentation, while intrinsically mitigating cumulative error propagation, a longstanding barrier to deep optical network scalability. We validated the robustness of OCiC through outdoor dark fibre deployments, confirming consistent and stable performance across varying environmental conditions. When scaled globally, OCiC transforms long-haul fibre infrastructure into a distributed photonic AI fabric with exascale potential, enabling reliable, low-latency telesurgery across distances up to 10,000 km and opening a new optical frontier for distributed medical intelligence.

As Large Language Models (LLMs) become increasingly integrated into software development workflows, they also become prime targets for adversarial attacks. Among these, backdoor attacks are a significant threat, allowing attackers to manipulate model outputs through hidden triggers embedded in training data. Detecting such backdoors remains a challenge, and one promising approach is the use of Spectral Signature defense methods that identify poisoned data by analyzing feature representations through eigenvectors. While some prior works have explored Spectral Signatures for backdoor detection in neural networks, recent studies suggest that these methods may not be optimally effective for code models. In this paper, we revisit the applicability of Spectral Signature-based defenses in the context of backdoor attacks on code models. We systematically evaluate their effectiveness under various attack scenarios and defense configurations, analyzing their strengths and limitations. We found that the widely used setting of Spectral Signature in code backdoor detection is often suboptimal. Hence, we explored the impact of different settings of the key factors. We discovered a new proxy metric that can more accurately estimate the actual performance of Spectral Signature without model retraining after the defense.

Internet of Things (IoT) networks generate diverse and high-volume traffic that reflects both normal activity and potential threats. Deriving meaningful insight from such telemetry requires cross-layer interpretation of behaviors, protocols, and context rather than isolated detection. This work presents an LLM-powered AI agent framework that converts raw packet captures into structured and semantically enriched representations for interactive analysis. The framework integrates feature extraction, transformer-based anomaly detection, packet and flow summarization, threat intelligence enrichment, and retrieval-augmented question answering. An AI agent guided by a large language model performs reasoning over the indexed traffic artifacts, assembling evidence to produce accurate and human-readable interpretations. Experimental evaluation on multiple IoT captures and six open models shows that hybrid retrieval, which combines lexical and semantic search with reranking, substantially improves BLEU, ROUGE, METEOR, and BERTScore results compared with dense-only retrieval. System profiling further indicates low CPU, GPU, and memory overhead, demonstrating that the framework achieves holistic and efficient interpretation of IoT network traffic.

Breast cancer is the most diagnosed cancer in women, with HER2 status critically guiding treatment decisions. Noninvasive prediction of HER2 status from dynamic contrast-enhanced MRI (DCE-MRI) could streamline diagnostics and reduce reliance on biopsy. However, preprocessing high-dynamic-range DCE-MRI into standardized 8-bit RGB format for pretrained neural networks is nontrivial, and normalization strategy significantly affects model performance. We benchmarked intensity normalization strategies using a Triple-Head Dual-Attention ResNet that processes RGB-fused temporal sequences from three DCE phases. Trained on a multicenter cohort (n=1,149) from the I-SPY trials and externally validated on BreastDCEDL_AMBL (n=43 lesions), our model outperformed transformer-based architectures, achieving 0.75 accuracy and 0.74 AUC on I-SPY test data. N4 bias field correction slightly degraded performance. Without fine-tuning, external validation yielded 0.66 AUC, demonstrating cross-institutional generalizability. These findings highlight the effectiveness of dual-attention mechanisms in capturing transferable spatiotemporal features for HER2 stratification, advancing reproducible deep learning biomarkers in breast cancer imaging.

When does a large language model (LLM) know what it does not know? Uncertainty quantification (UQ) provides measures of uncertainty, such as an estimate of the confidence in an LLM's generated output, and is therefore increasingly recognized as a crucial component of trusted AI systems. Black-box UQ methods do not require access to internal model information from the generating LLM and therefore have numerous real-world advantages, such as robustness to system changes, adaptability to choice of LLM, reduced costs, and computational tractability. In this paper, we investigate the effectiveness of UQ techniques that are primarily but not necessarily entirely black-box, where the consistency between a generated output and other sampled generations is used as a proxy for confidence in its correctness. We propose a high-level non-verbalized similarity-based aggregation framework that subsumes a broad swath of UQ approaches suitable for complex generative tasks, as well as introduce specific novel techniques from the framework that train confidence estimation models using small training sets. Through an empirical study with datasets spanning the diverse tasks of question answering, summarization, and text-to-SQL, we demonstrate that our proposed similarity-based methods can yield better calibrated confidences than baselines.

As large language models (LLMs) continue to advance rapidly, reliable governance tools have become critical. Publicly verifiable watermarking is particularly essential for fostering a trustworthy AI ecosystem. A central challenge persists: balancing text quality against detection robustness. Recent studies have sought to navigate this trade-off by leveraging signals from model output distributions (e.g., token-level entropy); however, their reliance on these model-specific signals presents a significant barrier to public verification, as the detection process requires access to the logits of the underlying model. We introduce STELA, a novel framework that aligns watermark strength with the linguistic degrees of freedom inherent in language. STELA dynamically modulates the signal using part-of-speech (POS) n-gram-modeled linguistic indeterminacy, weakening it in grammatically constrained contexts to preserve quality and strengthen it in contexts with greater linguistic flexibility to enhance detectability. Our detector operates without access to any model logits, thus facilitating publicly verifiable detection. Through extensive experiments on typologically diverse languages-analytic English, isolating Chinese, and agglutinative Korean-we show that STELA surpasses prior methods in detection robustness. Our code is available at https://github.com/Shinwoo-Park/stela_watermark.