Modern data-driven recommendation systems risk memorizing sensitive user behavioral patterns, raising privacy concerns. Existing recommendation unlearning methods, while capable of removing target data influence, suffer from inefficient unlearning speed and degraded performance, failing to meet real-time unlearning demands. Considering the ranking-oriented nature of recommendation systems, we present unranking, the process of reducing the ranking positions of target items while ensuring the formal guarantees of recommendation unlearning. To achieve efficient unranking, we propose Learning to Fast Unrank in Collaborative Filtering Recommendation (L2UnRank), which operates through three key stages: (a) identifying the influenced scope via interaction-based p-hop propagation, (b) computing structural and semantic influences for entities within this scope, and (c) performing efficient, ranking-aware parameter updates guided by influence information. Extensive experiments across multiple datasets and backbone models demonstrate L2UnRank's model-agnostic nature, achieving state-of-the-art unranking effectiveness and maintaining recommendation quality comparable to retraining, while also delivering a 50x speedup over existing methods. Codes are available at https://github.com/Juniper42/L2UnRank.

The rapid evolution of the gaming industry, driven by technological advancements and a burgeoning community, necessitates a deeper understanding of user sentiments, especially as expressed on popular social media platforms like YouTube. This study presents a sentiment analysis on video games based on YouTube comments, aiming to understand user sentiments within the gaming community. Utilizing YouTube API, comments related to various video games were collected and analyzed using the TextBlob sentiment analysis tool. The pre-processed data underwent classification using machine learning algorithms, including Naïve Bayes, Logistic Regression, and Support Vector Machine (SVM). Among these, SVM demonstrated superior performance, achieving the highest classification accuracy across different datasets. The analysis spanned multiple popular gaming videos, revealing trends and insights into user preferences and critiques. The findings underscore the importance of advanced sentiment analysis in capturing the nuanced emotions expressed in user comments, providing valuable feedback for game developers to enhance game design and user experience. Future research will focus on integrating more sophisticated natural language processing techniques and exploring additional data sources to further refine sentiment analysis in the gaming domain.

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power of PET scans and CSF biomarker analysis, which are prohibitively expensive to obtain for every patient. To address this cost-accuracy dilemma, we design a two-stage machine learning framework that selectively obtains advanced, costly features based on their predicted "value of information". We apply our framework to predict AD progression for MCI patients using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Our framework reduces the need for advanced testing by 20% while achieving a test AUROC of 0.929, comparable to the model that uses both basic and advanced features (AUROC=0.915, p=0.1010). We also provide an example interpretability analysis showing how one may explain the triage decision. Our work presents an interpretable, data-driven framework that optimizes AD diagnostic pathways and balances accuracy with cost, representing a step towards making early, reliable AD prediction more accessible in real-world practice. Future work should consider multiple categories of advanced features and larger-scale validation.

In the fast-moving consumer goods (FMCG) industry, deciding where to place physical assets, such as commercial beverage coolers, can directly impact revenue growth and execution efficiency. Although churn prediction and demand forecasting have been widely studied in B2B contexts, the use of machine learning to guide asset allocation remains relatively unexplored. This paper presents a framework focused on predicting which beverage clients are most likely to deliver strong returns in volume after receiving a cooler. Using a private dataset from a well-known Central American brewing and beverage company of 3,119 B2B traditional trade channel clients that received a cooler from 2022-01 to 2024-07, and tracking 12 months of sales transactions before and after cooler installation, three growth thresholds were defined: 10%, 30% and 50% growth in sales volume year over year. The analysis compares results of machine learning models such as XGBoost, LightGBM, and CatBoost combined with SHAP for interpretable feature analysis in order to have insights into improving business operations related to cooler allocation; the results show that the best model has AUC scores of 0.857, 0.877, and 0.898 across the thresholds on the validation set. Simulations suggest that this approach can improve ROI because it better selects potential clients to grow at the expected level and increases cost savings by not assigning clients that will not grow, compared to traditional volume-based approaches with substantial business management recommendations

Department of Multidisciplinary Engineering (AI & DS) Vishwakarma Institute of Technology, Pune, 411037, Maharashtra, India Abstract - Sepsis is a potentially fatal medical disorder that needs to be identified and treated right away to avoid fatalities. It must be quickly identified and treated in order to stop it from developing into severe sepsis, septic shock, and multi-organ failure. Sepsis remains a significant problem for doctors despite advancements in medical technology and treatment methods. The beginning of the disease has been successfully predicted by machine learning models in recent years, but due to their black-box character, it is challenging to interpret these predictions and comprehend the underlying illness mechanisms. In this research, we propose a comprehensible AI method for sepsis analysis that combines machine learning with clinical knowledge and expertise in the domain. Our method allows clinicians to understand and verify the model's predictions based on clinical expertise and preexisting beliefs, in addition to providing precise predictions of the onset of sepsis. Keywords - Sepsis, Artificial Intelligence, Machine Learning, Explainable AI, Sensitivity Analysis I. INTRODUCTION As the world continues to advance in technology, the potential of artificial intelligence (AI) in healthcare is becoming more apparent.

Drug-target interaction (DTI) prediction is of great significance for drug discovery and drug repurposing. With the accumulation of a large volume of valuable data, data-driven methods have been increasingly harnessed to predict DTIs, reducing costs across various dimensions. Therefore, this paper proposes a $\textbf{L}$arge $\textbf{L}$anguage $\textbf{M}$odel and $\textbf{M}$ulti-$\textbf{M}$odel data co-powered $\textbf{D}$rug $\textbf{T}$arget $\textbf{I}$nteraction prediction framework, named LLM$^3$-DTI. LLM$^3$-DTI constructs multi-modal data embedding to enhance DTI prediction performance. In this framework, the text semantic embeddings of drugs and targets are encoded by a domain-specific LLM. To effectively align and fuse multi-modal embedding. We propose the dual cross-attention mechanism and the TSFusion module. Finally, these multi-modal data are utilized for the DTI task through an output network. The experimental results indicate that LLM$^3$-DTI can proficiently identify validated DTIs, surpassing the performance of the models employed for comparison across diverse scenarios. Consequently, LLM$^3$-DTI is adept at fulfilling the task of DTI prediction with excellence. The data and code are available at https://github.com/chaser-gua/LLM3DTI.

Accurate accident anticipation is essential for enhancing the safety of autonomous vehicles (A Vs). However, existing methods often assume ideal conditions, overlooking challenges such as sensor failures, environmental disturbances, and data imperfections, which can significantly degrade prediction accuracy. Additionally, previous models have not adequately addressed the considerable variability in driver behavior and accident rates across different vehicle types. To overcome these limitations, this study introduces ROAR, a novel approach for accident detection and prediction. ROAR combines Discrete Wavelet Transform (DWT), a self-adaptive object-aware module, and dynamic focal loss to tackle these challenges. The DWT effectively extracts features from noisy and incomplete data, while the object-aware module improves accident prediction by focusing on high-risk vehicles and modeling the spatial-temporal relationships among traffic agents. Evaluated on three widely used datasets--Dashcam Accident Dataset (DAD), Car Crash Dataset (CCD), and AnAn Accident Detection (A3D)--our model consistently outperforms existing baselines in key metrics such as Average Precision (AP) and mean Time-to-Accident (mTT A). These results demonstrate the model's robustness in real-world conditions, particularly in handling sensor degradation, environmental noise, and imbalanced data distributions. This work offers a promising solution for reliable and accurate accident anticipation in complex traffic environments. INTRODUCTION Traffic accidents are a persistent global issue, causing significant harm to both individuals and society. With the rise of autonomous driving, the need to proactively address this challenge has never been more pressing [1].

The rapid proliferation of Internet of Things (IoT) devices has transformed numerous industries by enabling seamless connectivity and data-driven automation. However, this expansion has also exposed IoT networks to increasingly sophisticated security threats, including adversarial attacks targeting artificial intelligence (AI) and machine learning (ML)-based intrusion detection systems (IDS) to deliberately evade detection, induce misclassification, and systematically undermine the reliability and integrity of security defenses. To address these challenges, we propose a novel adversarial detection model that enhances the robustness of IoT IDS against adversarial attacks through SHapley Additive exPlanations (SHAP)-based fingerprinting. Using SHAP's DeepExplainer, we extract attribution fingerprints from network traffic features, enabling the IDS to reliably distinguish between clean and adversarially perturbed inputs. By capturing subtle attribution patterns, the model becomes more resilient to evasion attempts and adversarial manipulations. We evaluated the model on a standard IoT benchmark dataset, where it significantly outperformed a state-of-the-art method in detecting adversarial attacks. In addition to enhanced robustness, this approach improves model transparency and interpretability, thereby increasing trust in the IDS through explainable AI.

Connectomics - the mapping of neural connections in an organism's brain - currently requires extraordinary human effort to proofread the data collected from imaging and machine-learning assisted segmentation. With the growing excitement around using AI agents to automate important scientific tasks, we explore whether current AI systems can perform multiple tasks necessary for data proofreading. We introduce ConnectomeBench, a multimodal benchmark evaluating large language model (LLM) capabilities in three critical proofreading tasks: segment type identification, split error correction, and merge error detection. Using expert annotated data from two large open-source datasets - a cubic millimeter of mouse visual cortex and the complete Drosophila brain - we evaluate proprietary multimodal LLMs including Claude 3.7/4 Sonnet, o4-mini, GPT-4.1, GPT-4o, as well as open source models like InternVL-3 and NVLM. Our results demonstrate that current models achieve surprisingly high performance in segment identification (52-82% balanced accuracy vs. 20-25% chance) and binary/multiple choice split error correction (75-85% accuracy vs. 50% chance) while generally struggling on merge error identification tasks. Overall, while the best models still lag behind expert performance, they demonstrate promising capabilities that could eventually enable them to augment and potentially replace human proofreading in connectomics. Project page: https://github.com/jffbrwn2/ConnectomeBench and Dataset https://huggingface.co/datasets/jeffbbrown2/ConnectomeBench/tree/main

The early detection of mental health disorders from social media text is critical for enabling timely support, risk assessment, and referral to appropriate resources. This work introduces multiMentalRoBERTa, a fine-tuned RoBERTa model designed for multiclass classification of common mental health conditions, including stress, anxiety, depression, post-traumatic stress disorder (PTSD), suicidal ideation, and neutral discourse. Drawing on multiple curated datasets, data exploration is conducted to analyze class overlaps, revealing strong correlations between depression and suicidal ideation as well as anxiety and PTSD, while stress emerges as a broad, overlapping category. Comparative experiments with traditional machine learning methods, domain-specific transformers, and prompting-based large language models demonstrate that multiMentalRoBERTa achieves superior performance, with macro F1-scores of 0.839 in the six-class setup and 0.870 in the five-class setup (excluding stress), outperforming both fine-tuned MentalBERT and baseline classifiers. Beyond predictive accuracy, explainability methods, including Layer Integrated Gradients and KeyBERT, are applied to identify lexical cues that drive classification, with a particular focus on distinguishing depression from suicidal ideation. The findings emphasize the effectiveness of fine-tuned transformers for reliable and interpretable detection in sensitive contexts, while also underscoring the importance of fairness, bias mitigation, and human-in-the-loop safety protocols. Overall, multiMentalRoBERTa is presented as a lightweight, robust, and deployable solution for enhancing support in mental health platforms.