Background and objective Early diagnosis of gastric diseases is crucial to prevent fatal outcomes. Although histopathologic examination remains the diagnostic gold standard, it is performed entirely manually, making evaluations labor-intensive and prone to variability among pathologists. Critical findings may be missed, and lack of standard procedures reduces consistency. These limitations highlight the need for automated, reliable, and efficient methods for gastric tissue analysis. Methods In this study, a novel hybrid model named CoAtNeXt was proposed for the classification of gastric tissue images. The model is built upon the CoAtNet architecture by replacing its MBConv layers with enhanced ConvNeXtV2 blocks. Additionally, the Convolutional Block Attention Module (CBAM) is integrated to improve local feature extraction through channel and spatial attention mechanisms. The architecture was scaled to achieve a balance between computational efficiency and classification performance. CoAtNeXt was evaluated on two publicly available datasets, HMU-GC-HE-30K for eight-class classification and GasHisSDB for binary classification, and was compared against 10 Convolutional Neural Networks (CNNs) and ten Vision Transformer (ViT) models. Results CoAtNeXt achieved 96.47% accuracy, 96.60% precision, 96.47% recall, 96.45% F1 score, and 99.89% AUC on HMU-GC-HE-30K. On GasHisSDB, it reached 98.29% accuracy, 98.07% precision, 98.41% recall, 98.23% F1 score, and 99.90% AUC. It outperformed all CNN and ViT models tested and surpassed previous studies in the literature. Conclusion Experimental results show that CoAtNeXt is a robust architecture for histopathological classification of gastric tissue images, providing performance on binary and multiclass. Its highlights its potential to assist pathologists by enhancing diagnostic accuracy and reducing workload.

Three-dimensional X-ray histology techniques offer a non-invasive alternative to conventional 2D histology, enabling volumetric imaging of biological tissues without the need for physical sectioning or chemical staining. However, the inherent greyscale image contrast of X-ray tomography limits its biochemical specificity compared to traditional histological stains. Within digital pathology, deep learning-based virtual staining has demonstrated utility in simulating stained appearances from label-free optical images. In this study, we extend virtual staining to the X-ray domain by applying cross-modality image translation to generate artificially stained slices from synchrotron-radiation-based micro-CT scans. Using over 50 co-registered image pairs of micro-CT and toluidine blue-stained histology from bone-implant samples, we trained a modified CycleGAN network tailored for limited paired data. Whole slide histology images were downsampled to match the voxel size of the CT data, with on-the-fly data augmentation for patch-based training. The model incorporates pixelwise supervision and greyscale consistency terms, producing histologically realistic colour outputs while preserving high-resolution structural detail. Our method outperformed Pix2Pix and standard CycleGAN baselines across SSIM, PSNR, and LPIPS metrics. Once trained, the model can be applied to full CT volumes to generate virtually stained 3D datasets, enhancing interpretability without additional sample preparation. While features such as new bone formation were able to be reproduced, some variability in the depiction of implant degradation layers highlights the need for further training data and refinement. This work introduces virtual staining to 3D X-ray imaging and offers a scalable route for chemically informative, label-free tissue characterisation in biomedical research.

Accurate motion prediction of surrounding agents is crucial for the safe planning of autonomous vehicles. Recent advancements have extended prediction techniques from individual agents to joint predictions of multiple interacting agents, with various strategies to address complex interactions within future motions of agents. However, these methods overlook the evolving nature of these interactions. To address this limitation, we propose a novel progressive multi-scale decoding strategy, termed ProgD, with the help of dynamic heterogeneous graph-based scenario modeling. In particular, to explicitly and comprehensively capture the evolving social interactions in future scenarios, given their inherent uncertainty, we design a progressive modeling of scenarios with dynamic heterogeneous graphs. With the unfolding of such dynamic heterogeneous graphs, a factorized architecture is designed to process the spatio-temporal dependencies within future scenarios and progressively eliminate uncertainty in future motions of multiple agents. Furthermore, a multi-scale decoding procedure is incorporated to improve on the future scenario modeling and consistent prediction of agents' future motion. Introduction Motion prediction is important for self-driving systems to ensure safe and efficient navigation. Of particular interest is joint multi-agent motion prediction, which involves concurrently forecasting the future trajectories of all agents within a scene. This task has gained increasing attention recently, due to its complexity compared to marginal motion prediction, as it requires maintaining consistency and coherence in future motions of interactive agents, reflecting the intricate dynamics of real-world traffic. Without such consistency, the prediction module could produce conflicting trajectories, such as collisions between the predicted motions of agents, which would undermine the reliability of the system and lead to unsafe or infeasible motion plans. The challenge is further compounded by several intrinsic factors: (1) Dynamic and complex future social interactions.

Current evaluation metrics for deep learning weather models create a "Statistical Similarity Trap", rewarding blurry predictions while missing rare, high-impact events. We provide quantitative evidence of this trap, showing sophisticated baselines achieve 97.9% correlation yet 0.00 CSI for dangerous convection detection. We introduce DART (Dual Architecture for Regression Tasks), a framework addressing the challenge of transforming coarse atmospheric forecasts into high-resolution satellite brightness temperature fields optimized for extreme convection detection (below 220 K). DART employs dual-decoder architecture with explicit background/extreme decomposition, physically motivated oversampling, and task-specific loss functions. We present four key findings: (1) empirical validation of the Statistical Similarity Trap across multiple sophisticated baselines; (2) the "IVT Paradox", removing Integrated Water Vapor Transport, widely regarded as essential for atmospheric river analysis, improves extreme convection detection by 270%; (3) architectural necessity demonstrated through operational flexibility (DART achieves CSI = 0.273 with bias = 2.52 vs. 6.72 for baselines at equivalent CSI), and (4) real-world validation with the August 2023 Chittagong flooding disaster as a case study. To our knowledge, this is the first work to systematically address this hybrid conversion-segmentation-downscaling task, with no direct prior benchmarks identified in existing literature. Our validation against diverse statistical and deep learning baselines sufficiently demonstrates DART's specialized design. The framework enables precise operational calibration through beta-tuning, trains in under 10 minutes on standard hardware, and integrates seamlessly with existing meteorological workflows, demonstrating a pathway toward trustworthy AI for extreme weather preparedness.

Large Language Models (LLMs) are fast becoming indispensable tools for software developers, assisting or even partnering with them in crafting complex programs. The advantages are evident -- LLMs can significantly reduce development time, generate well-organized and comprehensible code, and occasionally suggest innovative ideas that developers might not conceive on their own. However, despite their strengths, LLMs will often introduce significant errors and present incorrect code with persuasive confidence, potentially misleading developers into accepting flawed solutions. In order to bring LLMs into the software development cycle in a more reliable manner, we propose a methodology for combining them with ``traditional'' software engineering techniques in a structured way, with the goal of streamlining the development process, reducing errors, and enabling users to verify crucial program properties with increased confidence. Specifically, we focus on the Scenario-Based Programming (SBP) paradigm -- an event-driven, scenario-based approach for software engineering -- to allow human developers to pour their expert knowledge into the LLM, as well as to inspect and verify its outputs. To evaluate our methodology, we conducted a significant case study, and used it to design and implement the Connect4 game. By combining LLMs and SBP we were able to create a highly-capable agent, which could defeat various strong existing agents. Further, in some cases, we were able to formally verify the correctness of our agent. Finally, our experience reveals interesting insights regarding the ease-of-use of our proposed approach. The full code of our case-study will be made publicly available with the final version of this paper.

West Lafayette, Indiana, USA Abstract--Zero-shot V oice Cloning (VC) and T ext-to-Speech (TTS) methods have advanced rapidly, enabling the generation of highly realistic synthetic speech and raising serious concerns about their misuse. While numerous detectors have been developed for English and Chinese, Spanish--spoken by over 600 million people worldwide--remains underrepresented in speech forensics. T o address this gap, we introduce HISPASpoof, the first large-scale Spanish dataset designed for synthetic speech detection and attribution. It includes real speech from public corpora across six accents and synthetic speech generated with six zero-shot TTS systems. We evaluate five representative methods, showing that detectors trained on English fail to generalize to Spanish, while training on HISPASpoof substantially improves detection. We also evaluate synthetic speech attribution performance on HISPASpoof, i.e., identifying the generation method of synthetic speech. HISPASpoof thus provides a critical benchmark for advancing reliable and inclusive speech forensics in Spanish. The rapid advancement of speech synthesis techniques has significantly transformed the area of audio generation and speech forensics. Recent Text-to-Speech (TTS) and V oice Cloning (VC) methods [1], [2], [3], [4], [5], [6] are now capable of producing highly realistic synthetic voices that closely mimic the spectral, prosodic, and linguistic traits of real human speech [7], [8], [9], [10].

We introduce LITcoder, an open-source library for building and benchmarking neural encoding models. Designed as a flexible backend, LITcoder provides standardized tools for aligning continuous stimuli (e.g., text and speech) with brain data, transforming stimuli into representational features, mapping those features onto brain data, and evaluating the predictive performance of the resulting model on held-out data. The library implements a modular pipeline covering a wide array of methodological design choices, so researchers can easily compose, compare, and extend encoding models without reinventing core infrastructure. Such choices include brain datasets, brain regions, stimulus feature (both neural-net-based and control, such as word rate), downsampling approaches, and many others. In addition, the library provides built-in logging, plotting, and seamless integration with experiment tracking platforms such as Weights & Biases (W&B). We demonstrate the scalability and versatility of our framework by fitting a range of encoding models to three story listening datasets: LeBel et al. (2023), Narratives, and Little Prince. We also explore the methodological choices critical for building encoding models for continuous fMRI data, illustrating the importance of accounting for all tokens in a TR scan (as opposed to just taking the last one, even when contextualized), incorporating hemodynamic lag effects, using train-test splits that minimize information leakage, and accounting for head motion effects on encoding model predictivity. Overall, LITcoder lowers technical barriers to encoding model implementation, facilitates systematic comparisons across models and datasets, fosters methodological rigor, and accelerates the development of high-quality high-performance predictive models of brain activity. Project page: https://litcoder-brain.github.io

Large language models (LLMs) excel in general-domain applications, yet their performance often degrades in specialized tasks requiring domain-specific knowledge. E-commerce is particularly challenging, as its data are noisy, heterogeneous, multilingual, and highly dynamic. We present Compass-v3, a vertical-domain Mixture-of-Experts (MoE) model with 245B total parameters and 71B active per token, designed for Southeast Asian e-commerce. Compass-v3 adopts fewer but larger experts, combined with hardware-efficient optimizations-such as intra-node expert parallelism and a customized memcpy operator-to maximize GPU utilization. The model is trained on 12T tokens of curated multilingual corpora and large-scale synthetic e-commerce instructions using a mixed-training strategy. To enhance alignment, we propose Optimal-Transport Direct Preference Optimization (OTPO), which captures token-level distinctions and improves instruction adherence in commerce-specific scenarios. Extensive evaluations demonstrate that Compass-v3 delivers state-of-the-art e-commerce performance, surpassing DeepSeek-V3.1, GPT-4 series, and Qwen3-235B. Moreover, Compass-v3 demonstrates strong multilingual capability across low-resource Southeast Asian languages (Indonesian, Thai, Filipino, Vietnamese, Malay, Taglog) and Portuguese while sustaining competitive performance on general benchmarks. It has already been widely applied in Shopee's industrial-scale e-commerce platform and is gradually replacing OpenAI's traffic, now accounting for over 70\% of total LLM usage, highlighting its dual strengths in specialized commerce expertise and broad linguistic competence.

We present CryptGNN, a secure and effective inference solution for third-party graph neural network (GNN) models in the cloud, which are accessed by clients as ML as a service (MLaaS). The main novelty of CryptGNN is its secure message passing and feature transformation layers using distributed secure multi-party computation (SMPC) techniques. CryptGNN protects the client's input data and graph structure from the cloud provider and the third-party model owner, and it protects the model parameters from the cloud provider and the clients. CryptGNN works with any number of SMPC parties, does not require a trusted server, and is provably secure even if P-1 out of P parties in the cloud collude. Theoretical analysis and empirical experiments demonstrate the security and efficiency of CryptGNN.

The cold-start user issue further compromises the effectiveness of recommender systems in limiting access to the historical behavioral information. It is an effective pipeline to optimize instructional prompts on a few-shot large language model (LLM) used in recommender tasks. We introduce a context-conditioned prompt formulation method P(u,\ Ds)\ \rightarrow\ R\widehat, where u is a cold-start user profile, Ds is a curated support set, and R\widehat is the predicted ranked list of items. Based on systematic experimentation with transformer-based autoregressive LLMs (BioGPT, LLaMA-2, GPT-4), we provide empirical evidence that optimal exemplar injection and instruction structuring can significantly improve the precision@k and NDCG scores of such models in low-data settings. The pipeline uses token-level alignments and embedding space regularization with a greater semantic fidelity. Our findings not only show that timely composition is not merely syntactic but also functional as it is in direct control of attention scales and decoder conduct through inference. This paper shows that prompt-based adaptation may be considered one of the ways to address cold-start recommendation issues in LLM-based pipelines.