With the growing volume of Internet of Things (IoT) network traffic, machine learning (ML)-based anomaly detection is more relevant than ever. Traditional batch learning models face challenges such as high maintenance and poor adaptability to rapid anomaly changes, known as concept drift. In contrast, streaming learning integrates online and incremental learning, enabling seamless updates and concept drift detection to improve robustness. This study investigates anomaly detection in streaming IoT traffic as binary classification, comparing batch and streaming learning approaches while assessing the limitations of current IoT traffic datasets. We simulated heterogeneous network data streams by carefully mixing existing datasets and streaming the samples one by one. Our results highlight the failure of batch models to handle concept drift, but also reveal persisting limitations of current datasets to expose model limitations due to low traffic heterogeneity. We also investigated the competitiveness of tree-based ML algorithms, well-known in batch anomaly detection, and compared it to non-tree-based ones, confirming the advantages of the former. Adaptive Random Forest achieved F1-score of 0.990 $\pm$ 0.006 at one-third the computational cost of its batch counterpart. Hoeffding Adaptive Tree reached F1-score of 0.910 $\pm$ 0.007, reducing computational cost by four times, making it a viable choice for online applications despite a slight trade-off in stability.

Abstract-- The oscillations of the human heart rate are inherently complex and non-linear--they are best described by mathematical chaos, and they present a challenge when applied to the practical domain of cardiovascular health monitoring in everyday life. In this work, we study the non-linear chaotic behavior of heart rate through mutual information and introduce a novel approach for enhancing heart rate estimation in real-life conditions. Our proposed approach not only explains and handles the non-linear temporal complexity from a mathematical perspective but also improves the deep learning solutions when combined with them. We validate our proposed method on four established datasets from real-life scenarios and compare its performance with existing algorithms thoroughly with extensive ablation experiments. Our results demonstrate a substantial improvement, up to 40%, of the proposed approach in estimating heart rate compared to traditional methods and existing machine-learning techniques while reducing the reliance on multiple sensing modalities and eliminating the need for post-processing steps. Healthy biological systems exhibit complex patterns of variability that can be described by mathematical chaos [1], [2]. A healthy heart is not a metronome; instead, its complex and constantly changing oscillations enable the cardiovascular system to rapidly adjust to sudden physical and psychological challenges to homeostasis [2]. Therefore, measuring heart rate (HR) during daily life has significant importance in monitoring individuals' health.

Enterprise systems are crucial for enhancing productivity and decision-making among employees and customers. Integrating LLM based systems into enterprise systems enables intelligent automation, personalized experiences, and efficient information retrieval, driving operational efficiency and strategic growth. However, developing and evaluating such systems is challenging due to the inherent complexity of enterprise environments, where data is fragmented across multiple sources and governed by sophisticated access controls. We present EnterpriseBench, a comprehensive benchmark that simulates enterprise settings, featuring 500 diverse tasks across software engineering, HR, finance, and administrative domains. Our benchmark uniquely captures key enterprise characteristics including data source fragmentation, access control hierarchies, and cross-functional workflows. Additionally, we provide a novel data generation pipeline that creates internally consistent enterprise tasks from organizational metadata. Experiments with state-of-the-art LLM agents demonstrate that even the most capable models achieve only 41.8% task completion, highlighting significant opportunities for improvement in enterprise-focused AI systems.

Abstract--Accurate prediction of Drug-T arget Affinity (DT A) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D structures, they still overlook simultaneous modeling of global sequence semantic features and local topological structural features within drugs and proteins, and represent drugs as flat sequences without atomic-level, substructural-level, and molecular-level multi-scale features. We propose HiF-DT A, a hierarchical network that adopts a dual-pathway strategy to extract both global sequence semantic and local topological features from drug and protein sequences, and models drugs multi-scale to learn atomic, substructural, and molecular representations fused via a multi-scale bilinear attention module. Experiments on Davis, KIBA, and Metz datasets show HiF-DT A outperforms state-of-the-art baselines, with ablations confirming the importance of global-local extraction and multi-scale fusion. Accurate prediction of drug-target affinity (DT A) is essential for drug screening, immune modulation and precision medicine.

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall short in providing any insights on the derivation process of recommendations -- a critical limitation in such high-stake applications. We propose TraceDR, a novel DR system operating over a medical knowledge graph (MKG), which ensures access to large-scale and high-quality information. TraceDR simultaneously predicts drug recommendations and related evidence within a multi-task learning framework, enabling traceability of medication recommendations. For covering a more diverse set of diseases and drugs than existing works, we devise a framework for automatically constructing patient health records and release DrugRec, a new large-scale testbed for DR.

Recently, there has been gradually more attention paid to Out-of-Distribution (OOD) performance prediction, whose goal is to predict the performance of trained models on unlabeled OOD test datasets, so that we could better leverage and deploy off-the-shelf trained models in risk-sensitive scenarios. Although progress has been made in this area, evaluation protocols in previous literature are inconsistent, and most works cover only a limited number of real-world OOD datasets and types of distribution shifts. T o provide convenient and fair comparisons for various algorithms, we propose Out-of-Distribution Performance Prediction Benchmark (ODP-Bench), a comprehensive benchmark that includes most commonly used OOD datasets and existing practical performance prediction algorithms. W e provide our trained models as a testbench for future researchers, thus guaranteeing the consistency of comparison and avoiding the burden of repeating the model training process. Furthermore, we also conduct in-depth experimental analyses to better understand their capability boundary.

Vision-Language Models (VLMs) excel in diverse multimodal tasks. However, user requirements vary across scenarios, which can be categorized into fast response, high-quality output, and low energy consumption. Relying solely on large models deployed in the cloud for all queries often leads to high latency and energy cost, while small models deployed on edge devices are capable of handling simpler tasks with low latency and energy cost. To fully leverage the strengths of both large and small models, we propose ECVL-ROUTER, the first scenario-aware routing framework for VLMs. Our approach introduces a new routing strategy and evaluation metrics that dynamically select the appropriate model for each query based on user requirements, maximizing overall utility. We also construct a multimodal response-quality dataset tailored for router training and validate the approach through extensive experiments. Results show that our approach successfully routes over 80% of queries to the small model while incurring less than 10% drop in problem solving probability. Vision-Language Models (VLMs), which integrate visual and textual understanding, have become crucial components in a wide range of AI applications, from robotics control to user interface navigation (Zhang et al., 2024; Shinde et al., 2025; Li et al., 2024). Moreover, a one-size-fits-all deployment strategy is suboptimal, as users increasingly expect systems that not only deliver high-quality responses but also adapt to diverse real-world scenarios with varying demands for latency, cost, and privacy. To effectively integrate the strengths of both L VLMs and SVLMs, edge-cloud collaborative routing(Y uan et al., 2025; Hao et al., 2024) is a natural fits. At its core is a lightweight model router (Ding et al., 2024; Ong et al., 2024) that inspects each query and selects an appropriate VLM. However, a general router is insufficient, routing must be scenario-aware: behaviors vary across diverse application contexts and can be configured by users or automatically inferred by scenario detection algorithms (Fifty et al., 2023; Someki et al., 2025). Existing routers are often text-centric and optimize a fixed trade-off between cost and quality, failing to adapt to multimodal, scenario-aware user needs. For example, real-time games interaction prioritizes low latency, medical diagnostics emphasizes answer quality, and mobile assistants require low energy use and strong privacy (Asgari et al., 2025).

Evaluating the abilities of large language models (LLMs) for tasks that require long-term memory and thus long-context reasoning, for example in conversational settings, is hampered by the existing benchmarks, which often lack narrative coherence, cover narrow domains, and only test simple recall-oriented tasks. This paper introduces a comprehensive solution to these challenges. First, we present a novel framework for automatically generating long (up to 10M tokens), coherent, and topically diverse conversations, accompanied by probing questions targeting a wide range of memory abilities. From this, we construct BEAM, a new benchmark comprising 100 conversations and 2,000 validated questions. Second, to enhance model performance, we propose LIGHT-a framework inspired by human cognition that equips LLMs with three complementary memory systems: a long-term episodic memory, a short-term working memory, and a scratchpad for accumulating salient facts. Our experiments on BEAM reveal that even LLMs with 1M token context windows (with and without retrieval-augmentation) struggle as dialogues lengthen. In contrast, LIGHT consistently improves performance across various models, achieving an average improvement of 3.5%-12.69% over the strongest baselines, depending on the backbone LLM. An ablation study further confirms the contribution of each memory component.

Manually conducting real-world data analyses is labor-intensive and inefficient. Despite numerous attempts to automate data science workflows, none of the existing paradigms or systems fully demonstrate all three key capabilities required to support them effectively: (1) open-domain data collection, (2) structured data transformation, and (3) analytic reasoning. To overcome these limitations, we propose DRAMA, an end-to-end paradigm that answers users' analytic queries in natural language on large-scale open-domain data. DRAMA unifies data collection, transformation, and analysis as a single pipeline. To quantitatively evaluate system performance on tasks representative of DRAMA, we construct a benchmark, DRAMA-Bench, consisting of two categories of tasks: claim verification and question answering, each comprising 100 instances. These tasks are derived from real-world applications that have gained significant public attention and require the retrieval and analysis of open-domain data. We develop DRAMA-Bot, a multi-agent system designed following DRAMA. It comprises a data retriever that collects and transforms data by coordinating the execution of sub-agents, and a data analyzer that performs structured reasoning over the retrieved data. We evaluate DRAMA-Bot on DRAMA-Bench together with five state-of-the-art baseline agents. DRAMA-Bot achieves 86.5% task accuracy at a cost of $0.05, outperforming all baselines with up to 6.9 times the accuracy and less than 1/6 of the cost. DRAMA is publicly available at https://github.com/uiuc-kang-lab/drama.

While Multimodal Large Language Models (MLLMs) have advanced GUI navigation agents, current approaches face limitations in cross-domain generalization and effective history utilization. We present a reasoning-enhanced framework that systematically integrates structured reasoning, action prediction, and history summarization. The structured reasoning component generates coherent Chain-of-Thought analyses combining progress estimation and decision reasoning, which inform both immediate action predictions and compact history summaries for future steps. Based on this framework, we train a GUI agent, \textbf{GUI-Rise}, through supervised fine-tuning on pseudo-labeled trajectories and reinforcement learning with Group Relative Policy Optimization (GRPO). This framework employs specialized rewards, including a history-aware objective, directly linking summary quality to subsequent action performance. Comprehensive evaluations on standard benchmarks demonstrate state-of-the-art results under identical training data conditions, with particularly strong performance in out-of-domain scenarios. These findings validate our framework's ability to maintain robust reasoning and generalization across diverse GUI navigation tasks. Code is available at https://leon022.github.io/GUI-Rise.