Ambient sensor-based human activity recognition (HAR) in smart homes remains challenging due to the need for real-time inference, spatially grounded reasoning, and context-aware temporal modeling. Existing approaches often rely on pre-segmented, within-activity data and overlook the physical layout of the environment, limiting their robustness in continuous, real-world deployments. In this paper, we propose MARAuder's Map, a novel framework for real-time activity recognition from raw, unsegmented sensor streams. Our method projects sensor activations onto the physical floorplan to generate trajectory-aware, image-like sequences that capture the spatial flow of human movement. These representations are processed by a hybrid deep learning model that jointly captures spatial structure and temporal dependencies. To enhance temporal awareness, we introduce a learnable time embedding module that encodes contextual cues such as hour-of-day and day-of-week. Additionally, an attention-based encoder selectively focuses on informative segments within each observation window, enabling accurate recognition even under cross-activity transitions and temporal ambiguity. Extensive experiments on multiple real-world smart home datasets demonstrate that our method outperforms strong baselines, offering a practical solution for real-time HAR in ambient sensor environments.

Within this field, Isolated Sign Language Recognition (ISLR) focuses on recognizing single, context-free signs, which can be seen as the building blocks for continuous sign language understanding. While ISLR provides an environment to study the visual and temporal characteristics of signs, it also poses significant challenges due to intra-class variations, such as differences in signing speed, hand orientation, and signer-dependent styles. Addressing these challenges is essential for building reliable models that can generalize across diverse signers and recording conditions. Moreover, the recognition of isolated signs provides a basis for Continuous Sign Language Recognition (CSLR), where the boundaries between consecutive signs are not explicitly defined. ISLR is typically formulated as a classification problem, where each video segment corresponds to a single label representing a sign.

Federated learning (FL) enables collaborative model training without exposing clients' private data, but its deployment is often constrained by the communication cost of transmitting gradients between clients and the central server, especially under system heterogeneity where low-bandwidth clients bottleneck overall performance. Lossy compression of gradient data can mitigate this overhead, and error-bounded lossy compression (EBLC) is particularly appealing for its fine-grained utility-compression tradeoff. However, existing EBLC methods (e.g., SZ), originally designed for smooth scientific data with strong spatial locality, rely on generic predictors such as Lorenzo and interpolation for entropy reduction to improve compression ratio. Gradient tensors, in contrast, exhibit low smoothness and weak spatial correlation, rendering these predictors ineffective and leading to poor compression ratios. To address this limitation, we propose an EBLC framework tailored for FL gradient data to achieve high compression ratios while preserving model accuracy. The core of it is an innovative prediction mechanism that exploits temporal correlations across FL training rounds and structural regularities within convolutional kernels to reduce residual entropy. The predictor is compatible with standard quantizers and entropy coders and comprises (1) a cross-round magnitude predictor based on a normalized exponential moving average, and (2) a sign predictor that leverages gradient oscillation and kernel-level sign consistency. Experiments show that this new EBLC yields up to 1.53x higher compression ratios than SZ3 with lower accuracy loss. Integrated into a real-world FL framework, APPFL, it reduces end-to-end communication time by 76.1%-96.2% under various constrained-bandwidth scenarios, demonstrating strong scalability for real-world FL deployments.

We conducted three 90 - minute workshops at Talenthub Op Zuid, each with a different group of participants (total N=24, MAge =17.6, SD=1.2, see S upplement for additional details). In the first workshop, participants reviewed the prior 13 personas from Stage 1 and critiqued them for gaps in relevance. The scoping personas generated from survey and forum data gave youth stakeholders a concrete starting point for consulting as experts by experience in initial co - design activities. They challenged the realism of the scoping personas . Using fill - in - the - blank templates to guide but not restrict their persona creation (created by a youth member of the research team with design training, see Supplement), youth added contextual details to the project personas, such as daily routines, stressors, and digital habits, and brainstormed plausible backstories involving bullying, school difficulties, or parental conflict. The second workshop engaged a new participant group who expanded on previous outputs and addressed additional questions on living environment and emotional support needs, as this was suggested as relevant by youth from the prior workshop . Participants revised or created new personas b ased on their own or peers' experiences. In t he third workshop, a new group of participants again reviewed prior co - creation and outputs and further refined the personas .

Large language models (LLMs) are increasingly examined as both behavioral subjects and decision systems, yet it remains unclear whether observed cognitive biases reflect surface imitation or deeper probability shifts. Anchoring bias, a classic human judgment bias, offers a critical test case. While prior work shows LLMs exhibit anchoring, most evidence relies on surface-level outputs, leaving internal mechanisms and attributional contributions unexplored. This paper advances the study of anchoring in LLMs through three contributions: (1) a log-probability-based behavioral analysis showing that anchors shift entire output distributions, with controls for training-data contamination; (2) exact Shapley-value attribution over structured prompt fields to quantify anchor influence on model log-probabilities; and (3) a unified Anchoring Bias Sensitivity Score integrating behavioral and attributional evidence across six open-source models. Results reveal robust anchoring effects in Gemma-2B, Phi-2, and Llama-2-7B, with attribution signaling that the anchors influence reweighting. Smaller models such as GPT-2, Falcon-RW-1B, and GPT-Neo-125M show variability, suggesting scale may modulate sensitivity. Attributional effects, however, vary across prompt designs, underscoring fragility in treating LLMs as human substitutes. The findings demonstrate that anchoring bias in LLMs is robust, measurable, and interpretable, while highlighting risks in applied domains. More broadly, the framework bridges behavioral science, LLM safety, and interpretability, offering a reproducible path for evaluating other cognitive biases in LLMs.

Sparse autoencoders (SAEs) have emerged as a powerful tool for interpreting large language models (LLMs) by decomposing token activations into combinations of human-understandable features. While SAEs provide crucial insights into LLM explanations, their practical adoption faces a fundamental challenge: better interpretability demands that SAEs' hidden layers have high dimensionality to satisfy sparsity constraints, resulting in prohibitive training and inference costs. Recent Mixture of Experts (MoE) approaches attempt to address this by partitioning SAEs into narrower expert networks with gated activation, thereby reducing computation. In a well-designed MoE, each expert should focus on learning a distinct set of features. However, we identify a \textit{critical limitation} in MoE-SAE: Experts often fail to specialize, which means they frequently learn overlapping or identical features. To deal with it, we propose two key innovations: (1) Multiple Expert Activation that simultaneously engages semantically weighted expert subsets to encourage specialization, and (2) Feature Scaling that enhances diversity through adaptive high-frequency scaling. Experiments demonstrate a 24\% lower reconstruction error and a 99\% reduction in feature redundancy compared to existing MoE-SAE methods. This work bridges the interpretability-efficiency gap in LLM analysis, allowing transparent model inspection without compromising computational feasibility.

This work introduces the quantum-inspired variational convolution (QiVC) framework, a novel learning paradigm that integrates principles of probabilistic inference, variational optimization, and quantum-inspired transformations within convolutional architectures. The central innovation of QiVC lies in its quantum-inspired rotated ensemble (QiRE) mechanism. QiRE performs differentiable low-dimensional subspace rotations of convolutional weights, analogously to quantum state evolution. This approach enables structured uncertainty modeling while preserving the intrinsic geometry of the parameter space, resulting in more expressive, stable, and uncertainty-aware representations. To demonstrate its practical potential, the concept is instantiated in a QiVC-based convolutional network (QiVC-Net) and evaluated in the context of biosignal classification, focusing on phonocardiogram (PCG) recordings, a challenging domain characterized by high noise, inter-subject variability, and often imbalanced data. The proposed QiVC-Net integrates an architecture in which the QiVC layer does not introduce additional parameters, instead performing an ensemble rotation of the convolutional weights through a structured mechanism ensuring robustness without added highly computational burden. Experiments on two benchmark datasets, PhysioNet CinC 2016 and PhysioNet CirCor DigiScope 2022, show that QiVC-Net achieves state-of-the-art performance, reaching accuracies of 97.84% and 97.89%, respectively. These findings highlight the versatility of the QiVC framework and its promise for advancing uncertainty-aware modeling in real-world biomedical signal analysis. The implementation of the QiVConv layer is openly available in GitHub.

Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative colitis. Traditional computational models often rely on structural information alone and thus fail to capture the genetic determinants that influence disease mechanisms and therapeutic responses. To address this gap, we propose GastroDL-Fusion, a dual-modal deep learning framework that integrates protein-ligand complex data with disease-associated gene sequence information for drug and vaccine development. In our approach, protein-ligand complexes are represented as molecular graphs and modeled using a Graph Isomorphism Network (GIN), while gene sequences are encoded into biologically meaningful embeddings via a pre-trained Transformer (ProtBERT/ESM). These complementary modalities are fused through a multi-layer perceptron to enable robust cross-modal interaction learning. We evaluate the model on benchmark datasets of GI disease-related targets, demonstrating that GastroDL-Fusion significantly improves predictive performance over conventional methods. Specifically, the model achieves a mean absolute error (MAE) of 1.12 and a root mean square error (RMSE) of 1.75, outperforming CNN, BiLSTM, GIN, and Transformer-only baselines. These results confirm that incorporating both structural and genetic features yields more accurate predictions of binding affinities, providing a reliable computational tool for accelerating the design of targeted therapies and vaccines in the context of gastrointestinal diseases.

Surgical resection of malignant solid tumors is critically dependent on the surgeon's ability to accurately identify pathological tissue and remove the tumor while preserving surrounding healthy structures. However, building an intraoperative 3D tumor model for subsequent removal faces major challenges due to the lack of high-fidelity tumor reconstruction, difficulties in developing generalized tissue models to handle the inherent complexities of tumor diagnosis, and the natural physical limitations of bimanual operation, physiologic tremor, and fatigue creep during surgery. To overcome these challenges, we introduce "TumorMap", a surgical robotic platform to formulate intraoperative 3D tumor boundaries and achieve autonomous tissue resection using a set of multifunctional lasers. TumorMap integrates a three-laser mechanism (optical coherence tomography, laser-induced endogenous fluorescence, and cutting laser scalpel) combined with deep learning models to achieve fully-automated and noncontact tumor resection. We validated TumorMap in murine osteoscarcoma and soft-tissue sarcoma tumor models, and established a novel histopathological workflow to estimate sensor performance. With submillimeter laser resection accuracy, we demonstrated multimodal sensor-guided autonomous tumor surgery without any human intervention.

Large language models such as GPT-4, Claude 3, and the Gemini series have improved automated reasoning and code generation. However, existing benchmarks mainly focus on accuracy and output quality, and they ignore an important factor: decoding token efficiency. In real systems, generating 10,000 tokens versus 100,000 tokens leads to large differences in latency, cost, and energy. In this work, we introduce OckBench, a model-agnostic and hardware-agnostic benchmark that evaluates both accuracy and token count for reasoning and coding tasks. Through experiments comparing multiple open- and closed-source models, we uncover that many models with comparable accuracy differ wildly in token consumption, revealing that efficiency variance is a neglected but significant axis of differentiation. We further demonstrate Pareto frontiers over the accuracy-efficiency plane and argue for an evaluation paradigm shift: we should no longer treat tokens as "free" to multiply. OckBench provides a unified platform for measuring, comparing, and guiding research in token-efficient reasoning. Our benchmarks are available at https://ockbench.github.io/ .