Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features that can later be adapted to specific clinical tasks with little additional supervision. In this review, we examine how FMs are being developed and applied in pathology, radiology, and ophthalmology, drawing on evidence from over 150 studies. We explain the core components of FM pipelines, including model architectures, self-supervised learning methods, and strategies for downstream adaptation. We also review how FMs are being used in each imaging domain and compare design choices across applications. Finally, we discuss key challenges and open questions to guide future research.

Developments in Deep Learning have significantly improved time series forecasting by enabling more accurate modeling of complex temporal dependencies inherent in sequential data. The effectiveness of such models is often demonstrated on limited sets of specific real-world data. Although this allows for comparative analysis, it still does not demonstrate how specific data characteristics align with the architectural strengths of individual models. Our research aims at uncovering clear connections between time series characteristics and particular models. We introduce a novel dataset generated using Gaussian Processes, specifically designed to display distinct, known characteristics for targeted evaluations of model adaptability to them. Furthermore, we present TimeFlex, a new model that incorporates a modular architecture tailored to handle diverse temporal dynamics, including trends and periodic patterns. This model is compared to current state-of-the-art models, offering a deeper understanding of how models perform under varied time series conditions.

This paper introduces PreP-OCR, a two-stage pipeline that combines document image restoration with semantic-aware post-OCR correction to enhance both visual clarity and textual consistency, thereby improving text extraction from degraded historical documents. First, we synthesize document-image pairs from plaintext, rendering them with diverse fonts and layouts and then applying a randomly ordered set of degradation operations. An image restoration model is trained on this synthetic data, using multi-directional patch extraction and fusion to process large images. Second, a ByT5 post-OCR model, fine-tuned on synthetic historical text pairs, addresses remaining OCR errors. Detailed experiments on 13,831 pages of real historical documents in English, French, and Spanish show that the PreP-OCR pipeline reduces character error rates by 63.9-70.3% compared to OCR on raw images. Our pipeline demonstrates the potential of integrating image restoration with linguistic error correction for digitizing historical archives.

--Recent advancements in Large Language Models (LLMs) have significantly expanded the capabilities of artificial intelligence in natural language processing tasks. Despite this progress, their performance in specialized domains such as computer science remains relatively unexplored. Understanding the proficiency of LLMs in these domains is critical for evaluating their practical utility and guiding future developments. The POSCOMP, a prestigious Brazilian examination used for graduate admissions in computer science promoted by the Brazlian Computer Society (SBC), provides a challenging benchmark. This study investigates whether LLMs can match or surpass human performance on the POSCOMP exam. Four LLMs - ChatGPT -4, Gemini 1.0 Advanced, Claude 3 Sonnet, and Le Chat Mistral Large - were initially evaluated on the 2022 and 2023 POSCOMP exams. The assessments measured the models' proficiency in handling complex questions typical of the exam. LLM performance was notably better on text-based questions than on image interpretation tasks. In the 2022 exam, ChatGPT - 4 led with 57 correct answers out of 69 questions, followed by Gemini 1.0 Advanced (49), Le Chat Mistral (48), and Claude 3 Sonnet (44). Similar trends were observed in the 2023 exam. ChatGPT -4 achieved the highest performance, surpassing all students who took the POSCOMP 2023 exam. LLMs, particularly ChatGPT -4, show promise in text-based tasks on the POSCOMP exam, although image interpretation remains a challenge. Given the rapid evolution of LLMs, we expanded our analysis to include more recent models - o1, Gemini 2.5 Pro, Claude 3.7 Sonnet, and o3-mini-high - evaluated on the 2022-2024 POSCOMP exams. These newer models demonstrate further improvements and consistently surpass both the average and top-performing human participants across all three years. The POSCOMP [1] is a prestigious assessment designed to test the knowledge of prospective computer science graduate students, promoted by the Brazilian Computer Society (SBC). It serves as an entry criterion for many graduate programs across Brazil. Using this exam as a benchmark for evaluating Large Language Models (LLMs) allows for a direct comparison between AI capabilities and human standards, offering valuable insights into the strengths and limitations of current AI models. Recent advancements in LLMs [2], [3] have significantly expanded the capabilities of Artificial Intelligence (AI), particularly in natural language processing tasks.

Large language models (LLMs) power many modern applications, but serving them at scale remains costly and resource-intensive. Current server-centric systems overlook consumer-grade GPUs at the edge. We introduce SpecEdge, an edge-assisted inference framework that splits LLM workloads between edge and server GPUs using a speculative decoding scheme, exchanging only token outputs over the network. SpecEdge employs proactive edge drafting to overlap edge token creation with server verification and pipeline-aware scheduling that interleaves multiple user requests to increase server-side throughput. Experiments show SpecEdge enhances overall cost efficiency by 1.91x through achieving 2.22x server throughput, and reduces inter token latency by 11.24% compared to a server-only baseline, introducing a scalable, cost-effective paradigm for LLM serving. The code is available at https://github.com/kaist-ina/specedge

As AI systems become more capable, deceptive behaviors can undermine evaluation and mislead users at deployment. Recent work has shown that lie detectors can accurately classify deceptive behavior, but they are not typically used in the training pipeline due to concerns around contamination and objective hacking. We examine these concerns by incorporating a lie detector into the labelling step of LLM post-training and evaluating whether the learned policy is genuinely more honest, or instead learns to fool the lie detector while remaining deceptive. Using DolusChat, a novel 65k-example dataset with paired truthful/deceptive responses, we identify three key factors that determine the honesty of learned policies: amount of exploration during preference learning, lie detector accuracy, and KL regularization strength. We find that preference learning with lie detectors and GRPO can lead to policies which evade lie detectors, with deception rates of over 85\%. However, if the lie detector true positive rate (TPR) or KL regularization is sufficiently high, GRPO learns honest policies. In contrast, off-policy algorithms (DPO) consistently lead to deception rates under 25\% for realistic TPRs. Our results illustrate a more complex picture than previously assumed: depending on the context, lie-detector-enhanced training can be a powerful tool for scalable oversight, or a counterproductive method encouraging undetectable misalignment.

Abstract--Mobile jammers pose a critical threat to 5G networks, particularly in military communications. This paper investigates an anti-jamming framework that enhances a strong adaptive beamforming baseline comprising Multiple Signal Classification (MUSIC) for Direction-of-Arrival (DoA) estimation and Minimum V ariance Distortionless Response (MVDR) for interference suppression with a lightweight machine learning (ML) model for predictive error correction. Extensive simulations in a realistic highway scenario demonstrate that the integrated system achieves a high DoA estimation accuracy of up to 99.8% and an average Signal-to-Noise Ratio (SNR) improvement of 9.58 dB. Analysis reveals that the MUSIC-MVDR baseline alone accounts for the vast majority of this performance gain (9.46 dB), indicating that the primary benefit of the simple ML model lies in correcting outlier estimates rather than providing a substantial systemic SNR increase. The framework's computational efficiency validates the effectiveness of the core beamforming approach and highlights the critical trade-off between ML model complexity and practical performance gains for securing 5G communications in contested environments.

With the widespread use of LLMs, preserving privacy in user prompts has become crucial, as prompts risk exposing privacy and sensitive data to the cloud LLMs. Traditional techniques like homomorphic encryption, secure multi-party computation, and federated learning face challenges due to heavy computational costs and user participation requirements, limiting their applicability in LLM scenarios. In this paper, we propose PromptObfus, a novel method for desensitizing LLM prompts. The core idea of PromptObfus is "anti-adversarial" learning, which perturbs privacy words in the prompt to obscure sensitive information while retaining the stability of model predictions. Specifically, PromptObfus frames prompt desensitization as a masked language modeling task, replacing privacy-sensitive terms with a [MASK] token. A desensitization model is trained to generate candidate replacements for each masked position. These candidates are subsequently selected based on gradient feedback from a surrogate model, ensuring minimal disruption to the task output. We demonstrate the effectiveness of our approach on three NLP tasks. Results show that PromptObfus effectively prevents privacy inference from remote LLMs while preserving task performance.

A crucial component for clinical risk prediction is developing a reliable prediction model is collecting high-quality time series clinical events. In this work, we release such a dataset that consists of 22,588,586 Clinical Time Series events, which we term MIMIC-\RNum{4}-Ext-22MCTS. Our source data are discharge summaries selected from the well-known yet unstructured MIMIC-IV-Note \cite{Johnson2023-pg}. The general-purpose MIMIC-IV-Note pose specific challenges for our work: it turns out that the discharge summaries are too lengthy for typical natural language models to process, and the clinical events of interest often are not accompanied with explicit timestamps. Therefore, we propose a new framework that works as follows: 1) we break each discharge summary into manageably small text chunks; 2) we apply contextual BM25 and contextual semantic search to retrieve chunks that have a high potential of containing clinical events; and 3) we carefully design prompts to teach the recently released Llama-3.1-8B \cite{touvron2023llama} model to identify or infer temporal information of the chunks. The obtained dataset is informative and transparent that standard models fine-tuned on the dataset achieves significant improvements in healthcare applications. In particular, the BERT model fine-tuned based on our dataset achieves 10\% improvement in accuracy on medical question answering task, and 3\% improvement in clinical trial matching task compared with the classic BERT. The dataset is available at https://physionet.org/content/mimic-iv-ext-22mcts/1.0.0. The codebase is released at https://github.com/JingWang-RU/MIMIC-IV-Ext-22MCTS-Temporal-Clinical-Time-Series-Dataset.

Deep learning has advanced weather forecasting, but accurate predictions first require identifying the current state of the atmosphere from observational data. In this work, we introduce Appa, a score-based data assimilation model generating global atmospheric trajectories at 0.25\si{\degree} resolution and 1-hour intervals. Powered by a 565M-parameter latent diffusion model trained on ERA5, Appa can be conditioned on arbitrary observations to infer plausible trajectories, without retraining. Our probabilistic framework handles reanalysis, filtering, and forecasting, within a single model, producing physically consistent reconstructions from various inputs. Results establish latent score-based data assimilation as a promising foundation for future global atmospheric modeling systems.