Generative AI technology based on Large Language Models (LLM) has been developed and applied to assist or automatically generate program codes. In this paper, we evaluate the capability of existing general LLMs for Basic Linear Algebra Subprograms (BLAS) code generation for CPUs. We use two LLMs provided by OpenAI: GPT-4.1, a Generative Pre-trained Transformer (GPT) model, and o4-mini, one of the o-series of Reasoning models. Both have been released in April 2025. For the routines from level-1 to 3 BLAS, we tried to generate (1) C code without optimization from routine name only, (2) C code with basic performance optimizations (thread parallelization, SIMD vectorization, and cache blocking) from routine name only, and (3) C code with basic performance optimizations based on Fortran reference code. As a result, we found that correct code can be generated in many cases even when only routine name are given. We also confirmed that thread parallelization with OpenMP, SIMD vectorization, and cache blocking can be implemented to some extent, and that the code is faster than the reference code.

The use of generative artificial intelligence (AI) models is becoming ubiquitous in many fields. Though progress continues to be made, general purpose large language AI models (LLM) show a tendency to deliver creative answers, often called "hallucinations", which have slowed their application in the medical and biomedical fields where accuracy is paramount. We propose that the design and use of much smaller, domain and even task-specific LM may be a more rational and appropriate use of this technology in biomedical research. In this work we apply a very small LM by today's standards to the specialized task of predicting regulatory interactions between molecular components to fill gaps in our current understanding of intracellular pathways. Toward this we attempt to correctly posit known pathway-informed interactions recovered from manually curated pathway databases by selecting and using only the most informative examples as part of an active learning scheme. With this example we show that a small (~110 million parameters) LM based on a Bidirectional Encoder Representations from Transformers (BERT) architecture can propose molecular interactions relevant to tuberculosis persistence and transmission with over 80% accuracy using less than 25% of the ~520 regulatory relationships in question. Using information entropy as a metric for the iterative selection of new tuning examples, we also find that increased accuracy is driven by favoring the use of the incorrectly assigned statements with the highest certainty (lowest entropy). In contrast, the concurrent use of correct but least certain examples contributed little and may have even been detrimental to the learning rate.

Large Language Models (LLMs) have transformed human-machine interaction since ChatGPT's 2022 debut, with Retrieval-Augmented Generation (RAG) emerging as a key framework that enhances LLM outputs by integrating external knowledge. However, RAG's reliance on ingesting external documents introduces new vulnerabilities. This paper exposes a critical security gap at the data loading stage, where malicious actors can stealthily corrupt RAG pipelines by exploiting document ingestion. We propose a taxonomy of 9 knowledge-based poisoning attacks and introduce two novel threat vectors -- Content Obfuscation and Content Injection -- targeting common formats (DOCX, HTML, PDF). Using an automated toolkit implementing 19 stealthy injection techniques, we test five popular data loaders, finding a 74.4% attack success rate across 357 scenarios. We further validate these threats on six end-to-end RAG systems -- including white-box pipelines and black-box services like NotebookLM and OpenAI Assistants -- demonstrating high success rates and critical vulnerabilities that bypass filters and silently compromise output integrity. Our results emphasize the urgent need to secure the document ingestion process in RAG systems against covert content manipulations.

We introduce GenAI-Powered Inference (GPI), a statistical framework for both causal and predictive inference using unstructured data, including text and images. GPI leverages open-source Generative Artificial Intelligence (GenAI) models - such as large language models and diffusion models - not only to generate unstructured data at scale but also to extract low-dimensional representations that capture their underlying structure. Applying machine learning to these representations, GPI enables estimation of causal and predictive effects while quantifying associated estimation uncertainty. Unlike existing approaches to representation learning, GPI does not require fine-tuning of generative models, making it computationally efficient and broadly accessible. We illustrate the versatility of the GPI framework through three applications: (1) analyzing Chinese social media censorship, (2) estimating predictive effects of candidates' facial appearance on electoral outcomes, and (3) assessing the persuasiveness of political rhetoric. An open-source software package is available for implementing GPI.

Generative AI and large language models (LLMs) offer significant potential for automating the extraction of structured information from web pages. In this work, we focus on food product pages from online retailers and explore schema-constrained extraction approaches to retrieve key product attributes, such as ingredient lists and nutrition tables. We compare two LLM-based approaches, direct extraction and indirect extraction via generated functions, evaluating them in terms of accuracy, efficiency, and cost on a curated dataset of 3,000 food product pages from three different online shops. Our results show that although the indirect approach achieves slightly lower accuracy (96.48\%, $-1.61\%$ compared to direct extraction), it reduces the number of required LLM calls by 95.82\%, leading to substantial efficiency gains and lower operational costs. These findings suggest that indirect extraction approaches can provide scalable and cost-effective solutions for large-scale information extraction tasks from template-based web pages using LLMs.

Large Language Models (LLMs) are transforming geospatial artificial intelligence (GeoAI), offering new capabilities in data processing, spatial analysis, and decision support. This paper examines the open-source paradigm's critical role in this transformation. While proprietary LLMs offer accessibility, they often limit the customization, interoperability, and transparency vital for specialized geospatial tasks. Conversely, open-source alternatives significantly advance Geographic Information Science (GIScience) by fostering greater adaptability, reproducibility, and community-driven innovation. Open frameworks empower researchers to tailor solutions, integrate cutting-edge methodologies (e.g., reinforcement learning, advanced spatial indexing), and align with FAIR (Findable, Accessible, Interoperable, and Reusable) principles. However, the growing reliance on any LLM necessitates careful consideration of security vulnerabilities, ethical risks, and robust governance for AI-generated geospatial outputs. This paper argues that GIScience advances best not through a single model type, but by cultivating a diverse, interoperable ecosystem combining open-source foundations for innovation, custom geospatial models, and interdisciplinary collaboration. By critically evaluating the opportunities and challenges of open-source LLMs within the broader GeoAI landscape, this work contributes to a thorough discourse on leveraging LLMs to effectively advance spatial research, policy, and decision-making in an equitable, sustainable, and scientifically rigorous manner.

--The recent proliferation of photorealistic AIgenerated images (AIGI) has raised urgent concerns about their potential misuse, particularly on social media platforms. Current state-of-the-art AIGI detection methods typically rely on large, deep neural architectures, creating significant computational barriers to real-time, large-scale deployment on platforms like social media. T o challenge this reliance on computationally intensive models, we introduce LAID, the first framework--to our knowledge--that benchmarks and evaluates the detection performance and efficiency of off-the-shelf lightweight neural networks. In this framework, we comprehensively train and evaluate selected models on a representative subset of the GenImage dataset across spatial, spectral, and fusion image domains. Our results demonstrate that lightweight models can achieve competitive accuracy, even under adversarial conditions, while incurring substantially lower memory and computation costs compared to current state-of-the-art methods. This study offers valuable insight into the trade-off between efficiency and performance in AIGI detection and lays a foundation for the development of practical, scalable, and trustworthy detection systems. The source code of LAID can be found at: https://github.com/nchivar/LAID. The rapid advancement of deep generative models such as Diffusion Models (DMs), Generative Adversarial Networks (GANs), and V ariational Autoencoders (V AEs) has enabled the generation of highly photorealistic synthetic imagery.

Scientific text is complex as it contains technical terms by definition. Simplifying such text for non-domain experts enhances accessibility of innovation and information. Politicians could be enabled to understand new findings on topics on which they intend to pass a law, or family members of seriously ill patients could read about clinical trials. The SimpleText CLEF Lab focuses on exactly this problem of simplification of scientific text. Task 1.1 of the 2025 edition specifically handles the simplification of complex sentences, so very short texts with little context. To tackle this task we investigate the identification of complex terms in sentences which are rephrased using small Gemini and OpenAI large language models for non-expert readers.

Accurate characterization of the equilibrium distributions of complex molecular systems and their dependence on environmental factors such as temperature is essential for understanding thermodynamic properties and transition mechanisms. Projecting these distributions onto meaningful low-dimensional representations enables interpretability and downstream analysis. Recent advances in generative AI, particularly flow models such as Normalizing Flows (NFs), have shown promise in modeling such distributions, but their scope is limited without tailored representation learning. In this work, we introduce Latent Thermodynamic Flows (LaTF), an end-to-end framework that tightly integrates representation learning and generative modeling. LaTF unifies the State Predictive Information Bottleneck (SPIB) with NFs to simultaneously learn low-dimensional latent representations, referred to as Collective Variables (CVs), classify metastable states, and generate equilibrium distributions across temperatures beyond the training data. The two components of representation learning and generative modeling are optimized jointly, ensuring that the learned latent features capture the system's slow, important degrees of freedom while the generative model accurately reproduces the system's equilibrium behavior. We demonstrate LaTF's effectiveness across diverse systems, including a model potential, the Chignolin protein, and cluster of Lennard Jones particles, with thorough evaluations and benchmarking using multiple metrics and extensive simulations. Finally, we apply LaTF to a RNA tetraloop system, where despite using simulation data from only two temperatures, LaTF reconstructs the temperature-dependent structural ensemble and melting behavior, consistent with experimental and prior extensive computational results.

Generative AI systems have rapidly advanced, with multimodal input capabilities enabling reasoning beyond text-based tasks. In education, these advancements could influence assessment design and question answering, presenting both opportunities and challenges. To investigate these effects, we introduce a high-quality dataset of 201 university-level STEM questions, manually annotated with features such as image type, role, problem complexity, and question format. Our study analyzes how these features affect generative AI performance compared to students. We evaluate four model families with five prompting strategies, comparing results to the average of 546 student responses per question. Although the best model correctly answers on average 58.5 % of the questions using majority vote aggregation, human participants consistently outperform AI on questions involving visual components. Interestingly, human performance remains stable across question features but varies by subject, whereas AI performance is susceptible to both subject matter and question features. Finally, we provide actionable insights for educators, demonstrating how question design can enhance academic integrity by leveraging features that challenge current AI systems without increasing the cognitive burden for students.