CEO Sam Altman announced an age-prediction system and new parental controls in a blog post on Tuesday. OpenAI announced new teen safety features for ChatGPT on Tuesday as part of an ongoing effort to respond to concerns about how minors engage with chatbots . The company is building an age-prediction system that identifies if a user is under 18 years old and routes them to an " age-appropriate " system that blocks graphic sexual content. If the system detects that the user is considering suicide or self-harm, it will contact the user's parents. In cases of imminent danger, if a user's parents are unreachable, the system may contact the authorities.

AI tools including Perplexity and Open AI's GPT-4 often provide one-sided answers to contentious questions, and don't back up their arguments with reliable sources How well-supported are the claims made by AI tools? Generative AI tools, and the deep research agents and search engines powered by them, frequently make unsupported and biased claims that aren't backed up by the sources they cite. That's according to an analysis which found that about one-third of answers provided by the AI tools aren't backed up by reliable sources. For OpenAI's GPT 4.5, the figure was even higher, at 47 per cent. Alongside this, they put five deep research agents through their paces: GPT-5's Deep Research feature, Bing Chat's Think Deeper option and deep research tools offered by You.com, Google Gemini and Perplexity.

BACKGROUND: For over a century, the New England Journal of Medicine Clinicopathological Conferences (CPCs) have tested the reasoning of expert physicians and, recently, artificial intelligence (AI). However, prior AI evaluations have focused on final diagnoses without addressing the multifaceted reasoning and presentation skills required of expert discussants. METHODS: Using 7102 CPCs (1923-2025) and 1021 Image Challenges (2006-2025), we conducted extensive physician annotation and automated processing to create CPC-Bench, a physician-validated benchmark spanning 10 text-based and multimodal tasks, against which we evaluated leading large language models (LLMs). Then, we developed "Dr. CaBot," an AI discussant designed to produce written and slide-based video presentations using only the case presentation, modeling the role of the human expert in these cases. RESULTS: When challenged with 377 contemporary CPCs, o3 (OpenAI) ranked the final diagnosis first in 60% of cases and within the top ten in 84% of cases, outperforming a 20-physician baseline; next-test selection accuracy reached 98%. Event-level physician annotations quantified AI diagnostic accuracy per unit of information. Performance was lower on literature search and image tasks; o3 and Gemini 2.5 Pro (Google) achieved 67% accuracy on image challenges. In blinded comparisons of CaBot vs. human expert-generated text, physicians misclassified the source of the differential in 46 of 62 (74%) of trials, and scored CaBot more favorably across quality dimensions. To promote research, we are releasing CaBot and CPC-Bench. CONCLUSIONS: LLMs exceed physician performance on complex text-based differential diagnosis and convincingly emulate expert medical presentations, but image interpretation and literature retrieval remain weaker. CPC-Bench and CaBot may enable transparent and continued tracking of progress in medical AI.

Modern tensor applications, especially foundation models and generative AI applications require multiple input modalities (both vision and language), which increases the demand for flexible accelerator architecture. Existing frameworks suffer from the trade-off between design flexibility and productivity of RTL generation: either limited to very few hand-written templates or cannot automatically generate the RTL. To address this challenge, we propose the LEGO framework, which targets tensor applications and automatically generates spatial architecture design and outputs synthesizable RTL code without handwritten RTL design templates. Leveraging the affine-transformation-based architecture representation, LEGO front end finds interconnections between function units, synthesizes the memory system, and fuses different spatial dataflow designs based on data reuse analysis. LEGO back end then translates the hardware in a primitive-level graph to perform lower-level optimizations, and applies a set of linear-programming algorithms to optimally insert pipeline registers and reduce the overhead of unused logic when switching spatial dataflows. Our evaluation demonstrates that LEGO can achieve 3.2x speedup and 2.4x energy efficiency compared to previous work Gemmini, and can generate one architecture for diverse modern foundation models in generative AI applications.

Online AI platforms for creating music from text prompts (AI music), such as Suno and Udio, are now being used by hundreds of thousands of users. Some AI music is appearing in advertising, and even charting, in multiple countries. How are these platforms being used? What subjects are inspiring their users? This article answers these questions for Suno and Udio using a large collection of songs generated by users of these platforms from May to October 2024. Using a combination of state-of-the-art text embedding models, dimensionality reduction and clustering methods, we analyze the prompts, tags and lyrics, and automatically annotate and display the processed data in interactive plots. Our results reveal prominent themes in lyrics, language preference, prompting strategies, as well as peculiar attempts at steering models through the use of metatags. To promote the musicological study of the developing cultural practice of AI-generated music we share our code and resources.

Intelligent tableware cleaning is a critical application in food safety and smart homes, but existing methods are limited by coarse-grained classification and scarcity of few-shot data, making it difficult to meet industrialization requirements. We propose DTGen, a few-shot data augmentation scheme based on generative diffusion models, specifically designed for fine-grained dirty tableware recognition. DTGen achieves efficient domain specialization through LoRA, generates diverse dirty images via structured prompts, and ensures data quality through CLIP-based cross-modal filtering. Under extremely limited real few-shot conditions, DTGen can synthesize virtually unlimited high-quality samples, significantly improving classifier performance and supporting fine-grained dirty tableware recognition. We further elaborate on lightweight deployment strategies, promising to transfer DTGen's benefits to embedded dishwashers and integrate with cleaning programs to intelligently regulate energy consumption and detergent usage. Research results demonstrate that DTGen not only validates the value of generative AI in few-shot industrial vision but also provides a feasible deployment path for automated tableware cleaning and food safety monitoring.

Career exploration is uncertain, requiring decisions with limited information and unpredictable outcomes. While generative AI offers new opportunities for career guidance, most systems rely on linear chat interfaces that produce overly comprehensive and idealized suggestions, overlooking the non-linear and effortful nature of real-world trajectories. We present CareerPooler, a generative AI-powered system that employs a pool-table metaphor to simulate career development as a spatial and narrative interaction. Users strike balls representing milestones, skills, and random events, where hints, collisions, and rebounds embody decision-making under uncertainty. In a within-subjects study with 24 participants, CareerPooler significantly improved engagement, information gain, satisfaction, and career clarity compared to a chatbot baseline. Qualitative findings show that spatial-narrative interaction fosters experience-based learning, resilience through setbacks, and reduced psychological burden. Our findings contribute to the design of AI-assisted career exploration systems and more broadly suggest that visually grounded analogical interactions can make generative systems engaging and satisfying.

Developing effective prompts demands significant cognitive investment to generate reliable, high-quality responses from Large Language Models (LLMs). By deploying case-specific prompt engineering techniques that streamline frequently performed life sciences workflows, researchers could achieve substantial efficiency gains that far exceed the initial time investment required to master these techniques. The Prompt Report published in 2025 outlined 58 different text-based prompt engineering techniques, highlighting the numerous ways prompts could be constructed. To provide actionable guidelines and reduce the friction of navigating these various approaches, we distil this report to focus on 6 core techniques: zero-shot, few-shot approaches, thought generation, ensembling, self-criticism, and decomposition. We breakdown the significance of each approach and ground it in use cases relevant to life sciences, from literature summarization and data extraction to editorial tasks. We provide detailed recommendations for how prompts should and shouldn't be structured, addressing common pitfalls including multi-turn conversation degradation, hallucinations, and distinctions between reasoning and non-reasoning models. We examine context window limitations, agentic tools like Claude Code, while analyzing the effectiveness of Deep Research tools across OpenAI, Google, Anthropic and Perplexity platforms, discussing current limitations. We demonstrate how prompt engineering can augment rather than replace existing established individual practices around data processing and document editing. Our aim is to provide actionable guidance on core prompt engineering principles, and to facilitate the transition from opportunistic prompting to an effective, low-friction systematic practice that contributes to higher quality research.

Artificial Intelligence Generated Content (AIGC) has rapidly emerged with the capability to generate different forms of content, including text, images, videos, and other modalities, which can achieve a quality similar to content created by humans. As a result, AIGC is now widely applied across various domains such as digital marketing, education, and public health, and has shown promising results by enhancing content creation efficiency and improving information delivery. However, there are few studies that explore the latest progress and emerging challenges of AIGC across different domains. To bridge this gap, this paper brings together 16 scholars from multiple disciplines to provide a cross-domain perspective on the trends and challenges of AIGC. Specifically, the contributions of this paper are threefold: (1) It first provides a broader overview of AIGC, spanning the training techniques of Generative AI, detection methods, and both the spread and use of AI-generated content across digital platforms. (2) It then introduces the societal impacts of AIGC across diverse domains, along with a review of existing methods employed in these contexts. (3) Finally, it discusses the key technical challenges and presents research propositions to guide future work. Through these contributions, this vision paper seeks to offer readers a cross-domain perspective on AIGC, providing insights into its current research trends, ongoing challenges, and future directions.

Neural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive self-regulatory dynamics of living matter. By embedding Artificial Neural Networks (ANNs) as local decision-making centers and interaction rules between localized agents, NCA can simulate processes across molecular, cellular, tissue, and system-level scales, offering a multiscale competency architecture perspective on evolution, development, regeneration, aging, morphogenesis, and robotic control. These models not only reproduce biologically inspired target patterns but also generalize to novel conditions, demonstrating robustness to perturbations and the capacity for open-ended adaptation and reasoning. Given their immense success in recent developments, we here review current literature of NCAs that are relevant primarily for biological or bioengineering applications. Moreover, we emphasize that beyond biology, NCAs display robust and generalizing goal-directed dynamics without centralized control, e.g., in controlling or regenerating composite robotic morphologies or even on cutting-edge reasoning tasks such as ARC-AGI-1. In addition, the same principles of iterative state-refinement is reminiscent to modern generative Artificial Intelligence (AI), such as probabilistic diffusion models. Their governing self-regulatory behavior is constraint to fully localized interactions, yet their collective behavior scales into coordinated system-level outcomes. We thus argue that NCAs constitute a unifying computationally lean paradigm that not only bridges fundamental insights from multiscale biology with modern generative AI, but have the potential to design truly bio-inspired collective intelligence capable of hierarchical reasoning and control.