Recent work has examined the estimation of models of stimulus-driven neural activity in which some linear filtering process is followed by a nonlinear, probabilistic spiking stage. We analyze the estimation of one such model for which this nonlinear step is implemented by a noisy, leaky, integrate-and-fire mechanism with a spike-dependent aftercurrent. Thismodel is a biophysically plausible alternative to models with Poisson (memory-less) spiking, and has been shown to effectively reproduce various spiking statistics of neurons in vivo. However, the problem of estimating the model from extracellular spike train data has not been examined in depth. We formulate the problem in terms of maximum likelihoodestimation, and show that the computational problem of maximizing the likelihood is tractable.

Consider a number of moving points, where each point is attached to a joint of the human body and projected onto an image plane. Johannson showed that humans can effortlessly detect and recognize thepresence of other humans from such displays. This is true even when some of the body points are missing (e.g. because of occlusion) and unrelated clutter points are added to the display. We are interested in replicating this ability in a machine. To this end, we present a labelling and detection scheme in a probabilistic framework. Our method is based on representing the joint probability densityof positions and velocities of body points with a graphical model, and using Loopy Belief Propagation to calculate a likely interpretation of the scene. Furthermore, we introduce a global variable representing the body's centroid. Experiments on one motion-captured sequence suggest that our scheme improves on the accuracy of a previous approach based on triangulated graphical models,especially when very few parts are visible. The improvement isdue both to the more general graph structure we use and, more significantly, to the introduction of the centroid variable.

Rao-Blackwellization is an approximation technique for probabilistic inference thatflexibly combines exact inference with sampling. It is useful in models where conditioning on some of the variables leaves a simpler inferenceproblem that can be solved tractably. This paper presents Sample Propagation, an efficient implementation of Rao-Blackwellized approximate inference for a large class of models. Sample Propagation tightly integrates sampling with message passing in a junction tree, and is named for its simple, appealing structure: it walks the clusters of a junction tree, sampling some of the current cluster's variables and then passing a message to one of its neighbors. We discuss the application of Sample Propagation to conditional Gaussian inference problems such as switching linear dynamical systems.

That is, each factor sends a "message" to all pairs of nodes

In pattern classification tasks, errors are introduced because of differences betweenthe true model and the one obtained via model estimation. Using likelihood-ratio based classification, it is possible to correct for this discrepancy by finding class-pair specific terms to adjust the likelihood ratio directly, and that can make class-pair preference relationships intransitive. Inthis work, we introduce new methodology that makes necessary corrections to the likelihood ratio, specifically those that are necessary toachieve perfect classification (but not perfect likelihood-ratio correction which can be overkill). The new corrections, while weaker than previously reported such adjustments, are analytically challenging since they involve discontinuous functions, therefore requiring several approximations. We test a number of these new schemes on an isolatedword speechrecognition task as well as on the UCI machine learning data sets. Results show that by using the bias terms calculated in this new way, classification accuracy can substantially improve over both the baseline and over our previous results.

In this paper we introduce another prior over the dynamics of a(t). We assume that fluctuations in a(t) have a 1 / f spectrum, as observed ubiquitously in nature.

We present a Bayesian approach to color constancy which utilizes a non-Gaussian probabilistic model of the image formation process.

When we model a higher order functions, such as learning and memory, we face a difficulty of comparing neural activities with hidden variables that depend on the history of sensory and motor signals and the dynamics ofthe network. Here, we propose novel method for estimating hidden variables of a learning agent, such as connection weights from sequences of observable variables. Bayesian estimation is a method to estimate the posterior probability of hidden variables from observable data sequence using a dynamic model of hidden and observable variables.

We present an analysis of concentration-of-expectation phenomena in layered Bayesian networks that use generalized linear models as the local conditional probabilities. This framework encompasses a wide variety of probability distributions, including both discrete and continuous random variables. We utilize ideas from large deviation analysis and the delta method to devise and evaluate a class of approximate inference algorithms forlayered Bayesian networks that have superior asymptotic error bounds and very fast computation time.

Existing source location and recovery algorithms used in magnetoencephalographic imaginggenerally assume that the source activity at different brain locations is independent or that the correlation structure is known.