Complexity theory of circuits strongly suggests that deep architectures can be much more efficient (sometimes exponentially) than shallow architectures, in terms of computational elements required to represent some functions. Deep multi-layer neural networks have many levels of non-linearities allowing them to compactly represent highly nonlinear and highly-varying functions. However, until recently it was not clear how to train such deep networks, since gradient-based optimization starting from random initialization appears to often get stuck in poor solutions. Hinton et al. recently introduced a greedy layer-wise unsupervised learning algorithm for Deep Belief Networks (DBN), a generative model with many layers of hidden causal variables. In the context of the above optimization problem, we study this algorithm empirically and explore variants to better understand its success and extend it to cases where the inputs are continuous or where the structure of the input distribution is not revealing enough about the variable to be predicted in a supervised task. Our experiments also confirm the hypothesis that the greedy layer-wise unsupervised training strategy mostly helps the optimization, by initializing weights in a region near a good local minimum, giving rise to internal distributed representations that are high-level abstractions of the input, bringing better generalization.

We introduce Coherent Point Drift (CPD), a novel probabilistic method for nonrigid registrationof point sets. The registration is treated as a Maximum Likelihood (ML)estimation problem with motion coherence constraint over the velocity field such that one point set moves coherently to align with the second set. We formulate the motion coherence constraint and derive a solution of regularized ML estimation through the variational approach, which leads to an elegant kernel form. We also derive the EM algorithm for the penalized ML optimization with deterministic annealing. The CPD method simultaneously finds both the nonrigid transformation and the correspondence between two point sets without making any prior assumption of the transformation model except that of motion coherence. Thismethod can estimate complex nonlinear nonrigid transformations, and is shown to be accurate on 2D and 3D examples and robust in the presence of outliers and missing points.

The study of point cloud data sampled from a stratification, a collection of manifolds withpossible different dimensions, is pursued in this paper. We present a technique for simultaneously soft clustering and estimating the mixed dimensionality anddensity of such structures. The framework is based on a maximum likelihood estimationof a Poisson mixture model. The presentation of the approach is completed with artificial and real examples demonstrating the importance of extending manifold learning to stratification learning.

Correlation between instances is often modelled via a kernel function using input attributesof the instances. Relational knowledge can further reveal additional pairwise correlations between variables of interest. In this paper, we develop a class of models which incorporates both reciprocal relational information and input attributesusing Gaussian process techniques. This approach provides a novel nonparametric Bayesian framework with a data-dependent covariance function for supervised learning tasks. We also apply this framework to semi-supervised learning. Experimental results on several real world data sets verify the usefulness of this algorithm.

Many recent studies analyze how data from different modalities can be combined. Often this is modeled as a system that optimally combines several sources of information aboutthe same variable. However, it has long been realized that this information combining depends on the interpretation of the data. Two cues that are perceived by different modalities can have different causal relationships: (1) They can both have the same cause, in this case we should fully integrate both cues into a joint estimate.

We consider the problem of inferring the structure of a network from cooccurrence data:observations that indicate which nodes occur in a signaling pathway but do not directly reveal node order within the pathway. This problem is motivated by network inference problems arising in computational biology and communication systems, in which it is difficult or impossible to obtain precise time ordering information. Without order information, every permutation of the activated nodes leads to a different feasible solution, resulting in combinatorial explosion of the feasible set. However, physical principles underlying most networked systemssuggest that not all feasible solutions are equally likely. Intuitively, nodes that cooccur more frequently are probably more closely connected. Building on this intuition, we model path co-occurrences as randomly shuffled samples of a random walk on the network. We derive a computationally efficient network inference algorithm and, via novel concentration inequalities for importance samplingestimators, prove that a polynomial complexity Monte Carlo version of the algorithm converges with high probability.

We present a hierarchical Bayesian model for sets of related, but different, classes of time series data. Our model performs alignment simultaneously across all classes, while detecting and characterizing class-specific differences. During inference themodel produces, for each class, a distribution over a canonical representation ofthe class. These class-specific canonical representations are automatically aligned to one another -- preserving common substructures, and highlighting differences.

Everyday inductive reasoning draws on many kinds of knowledge, including knowledge about relationships between properties and knowledge about relationships between objects. Previous accounts of inductive reasoning generally focus on just one kind of knowledge: models of causal reasoning often focus on relationships between properties, and models of similarity-based reasoning often focus on similarity relationships between objects. We present a Bayesian model of inductive reasoning that incorporates both kinds of knowledge, and show that it accounts well for human inferences about the properties of biological species.

Latent Dirichlet allocation (LDA) is a Bayesian network that has recently gained much popularity in applications ranging from document modeling to computer vision. Due to the large scale nature of these applications, current inference procedures like variational Bayes and Gibbs sampling have been found lacking. In this paper we propose the collapsed variational Bayesian inference algorithm for LDA, and show that it is computationally efficient, easy to implement and significantly more accurate than standard variational Bayesian inference for LDA.

Bayesian method applied to these models is an attractive approach, used successfully in applications ranging from acoustics t0 bioinformatics.