The co-design of robot morphology and neural control typically requires using reinforcement learning to approximate a unique control policy gradient for each body plan, demanding massive amounts of training data to measure the performance of each design. Here we show that a universal, morphology-agnostic controller can be rapidly and directly obtained by gradient-based optimization through differentiable simulation. This process of morphological pretraining allows the designer to explore non-differentiable changes to a robot's physical layout (e.g. adding, removing and recombining discrete body parts) and immediately determine which revisions are beneficial and which are deleterious using the pretrained model. We term this process "zero-shot evolution" and compare it with the simultaneous co-optimization of a universal controller alongside an evolving design population. We find the latter results in diversity collapse, a previously unknown pathology whereby the population -- and thus the controller's training data -- converges to similar designs that are easier to steer with a shared universal controller. We show that zero-shot evolution with a pretrained controller quickly yields a diversity of highly performant designs, and by fine-tuning the pretrained controller on the current population throughout evolution, diversity is not only preserved but significantly increased as superior performance is achieved.

Visual data is used in numerous different scientific workflows ranging from remote sensing to ecology. As the amount of observation data increases, the challenge is not just to make accurate predictions but also to understand the underlying mechanisms for those predictions. Good interpretation is important in scientific workflows, as it allows for better decision-making by providing insights into the data. This paper introduces an automatic way of obtaining such interpretable-by-design models, by learning programs that interleave neural networks. We propose DiSciPLE (Discovering Scientific Programs using LLMs and Evolution) an evolutionary algorithm that leverages common sense and prior knowledge of large language models (LLMs) to create Python programs explaining visual data. Additionally, we propose two improvements: a program critic and a program simplifier to improve our method further to synthesize good programs. On three different real-world problems, DiSciPLE learns state-of-the-art programs on novel tasks with no prior literature. For example, we can learn programs with 35% lower error than the closest non-interpretable baseline for population density estimation.

Molecular discovery has brought great benefits to the chemical industry. Various molecule design techniques are developed to identify molecules with desirable properties. Traditional optimization methods, such as genetic algorithms, continue to achieve state-of-the-art results across multiple molecular design benchmarks. However, these techniques rely solely on random walk exploration, which hinders both the quality of the final solution and the convergence speed. To address this limitation, we propose a novel approach called Gradient Genetic Algorithm (Gradient GA), which incorporates gradient information from the objective function into genetic algorithms. Instead of random exploration, each proposed sample iteratively progresses toward an optimal solution by following the gradient direction. We achieve this by designing a differentiable objective function parameterized by a neural network and utilizing the Discrete Langevin Proposal to enable gradient guidance in discrete molecular spaces. Experimental results demonstrate that our method significantly improves both convergence speed and solution quality, outperforming cutting-edge techniques. For example, it achieves up to a 25% improvement in the top-10 score over the vanilla genetic algorithm. The code is publicly available at https://github.com/debadyuti23/GradientGA.

A well-balanced exploration-exploitation trade-off is crucial for successful acquisition functions in Bayesian optimization. However, there is a lack of quantitative measures for exploration, making it difficult to analyze and compare different acquisition functions. This work introduces two novel approaches - observation traveling salesman distance and observation entropy - to quantify the exploration characteristics of acquisition functions based on their selected observations. Using these measures, we examine the explorative nature of several well-known acquisition functions across a diverse set of black-box problems, uncover links between exploration and empirical performance, and reveal new relationships among existing acquisition functions. Beyond enabling a deeper understanding of acquisition functions, these measures also provide a foundation for guiding their design in a more principled and systematic manner.

With the expansion of data availability, machine learning (ML) has achieved remarkable breakthroughs in both academia and industry. However, imbalanced data distributions are prevalent in various types of raw data and severely hinder the performance of ML by biasing the decision-making processes. To deepen the understanding of imbalanced data and facilitate the related research and applications, this survey systematically analyzing various real-world data formats and concludes existing researches for different data formats into four distinct categories: data re-balancing, feature representation, training strategy, and ensemble learning. This structured analysis help researchers comprehensively understand the pervasive nature of imbalance across diverse data format, thereby paving a clearer path toward achieving specific research goals. we provide an overview of relevant open-source libraries, spotlight current challenges, and offer novel insights aimed at fostering future advancements in this critical area of study.

Vision systems in nature show remarkable diversity, from simple light-sensitive patches to complex camera eyes with lenses. While natural selection has produced these eyes through countless mutations over millions of years, they represent just one set of realized evolutionary paths. Testing hypotheses about how environmental pressures shaped eye evolution remains challenging since we cannot experimentally isolate individual factors. Computational evolution offers a way to systematically explore alternative trajectories. Here we show how environmental demands drive three fundamental aspects of visual evolution through an artificial evolution framework that co-evolves both physical eye structure and neural processing in embodied agents. First, we demonstrate computational evidence that task specific selection drives bifurcation in eye evolution - orientation tasks like navigation in a maze leads to distributed compound-type eyes while an object discrimination task leads to the emergence of high-acuity camera-type eyes. Second, we reveal how optical innovations like lenses naturally emerge to resolve fundamental tradeoffs between light collection and spatial precision. Third, we uncover systematic scaling laws between visual acuity and neural processing, showing how task complexity drives coordinated evolution of sensory and computational capabilities. Our work introduces a novel paradigm that illuminates evolutionary principles shaping vision by creating targeted single-player games where embodied agents must simultaneously evolve visual systems and learn complex behaviors. Through our unified genetic encoding framework, these embodied agents serve as next-generation hypothesis testing machines while providing a foundation for designing manufacturable bio-inspired vision systems. Website: http://eyes.mit.edu/

Summary and Contributions: The paper tries to understand the mechanisms that potentially make human vision robust to test-time adversarial attacks. Two biologically plausible mechanisms are considered: 1) Retinal fixation: The first mechanism models the non-uniform sampling of the image performed by the retina due to uneven distribution of cones. This mechanism essentially involves subsampling and upsampling the pixels of the image. The density of sampling is highest at a fixation point on an image and decreases with distance from the fixation point. The final predicted output is the average of predicted output for subsampled images with different fixation points.

The paper was heavily discussed among all the reviewers, and in the end, the reviewers greed that the contributions of the paper are sufficiently significant (in terms of the scientific method and insights to the computational neuroscience community). The paper provides two neuroscience-inspired mechanisms are improve robustness of NNs to adversarial attacks. "Retinal fixations" stands for a non-uniform sampling of the visual field around the fixation point (densest close to the center); "Cortical fixations" is a multi-scale processing by smaller branches of the network. Both mechanisms seem to work to some extent for small perturbations. The reviewers also had a number of suggestions which will certainly improve the quality of the results (esp. to the ML audience).

In this paper, we experiment with novelty-based variants of OpenAI-ES, the NS-ES and NSR-ES algorithms, and evaluate their effectiveness in training complex, transformer-based architectures designed for the problem of reinforcement learning such as Decision Transformers. We also test if we can accelerate the novelty-based training of these larger models by seeding the training by a pretrained models. By this, we build on our previous work, where we tested the ability of evolution strategies - specifically the aforementioned OpenAI-ES - to train the Decision Transformer architecture. The results were mixed. NS-ES showed progress, but it would clearly need many more iterations for it to yield interesting results. NSR-ES, on the other hand, proved quite capable of being straightforwardly used on larger models, since its performance appears as similar between the feed-forward model and Decision Transformer, as it was for the OpenAI-ES in our previous work.

AI advancements have been significantly driven by a combination of foundation models and curiosity-driven learning aimed at increasing capability and adaptability. A growing area of interest within this field is Open-Endedness - the ability of AI systems to continuously and autonomously generate novel and diverse artifacts or solutions. This has become relevant for accelerating scientific discovery and enabling continual adaptation in AI agents. This position paper argues that the inherently dynamic and self-propagating nature of Open-Ended AI introduces significant, underexplored risks, including challenges in maintaining alignment, predictability, and control. This paper systematically examines these challenges, proposes mitigation strategies, and calls for action for different stakeholders to support the safe, responsible and successful development of Open-Ended AI.