Artificial intelligence, or AI, is largely an experimental science—at least as much progress has been made by building and analyzing programs as by examining theoretical questions. MYCIN is one of several well-known programs that embody some intelligence and provide data on the extent to which intelligent behavior can be programmed. As with other AI programs, its development was slow and not always in a forward direction. But we feel we learned some useful lessons in the course of nearly a decade of work on MYCIN and related programs. In this book we share the results of many experiments performed in that time, and we try to paint a coherent picture of the work. The book is intended to be a critical analysis of several pieces of related research, performed by a large number of scientists. We believe that the whole field of AI will benefit from such attempts to take a detailed retrospective look at experiments, for in this way the scientific foundations of the field will gradually be defined. It is for all these reasons that we have prepared this analysis of the MYCIN experiments.

JANICE S. AIKINS Dr. Aikins received her Ph.D. in computer science from Stanford University in 1980. She is currently a research computer scientist at IBM's Palo Alto Scientific Center. She specializes in designing systems with an emphasis on the explicit representation of control knowledge in expert systems. ROBERT L. BLUM Dr. Blum received his M.D. from the University of California Medical School at San Francisco in 1973. From 1973 to 1976 he did an internship and residency in the Department of Internal Medicine at the Kaiser Foundation Hospital in Oakland, California, where he was chief resident in 1976.

Edward H. Shortliffe Chapter 6 Details of the Revised Therapy Algorithm

Anomaly detection is an important problem that has been well-studied within diverse research areas and application domains. The aim of this survey is twofold, firstly we present a structured and comprehensive overviewof research methods in deep learning-based anomaly detection. Furthermore, we review the adoption of these methods for anomaly across various application domains and assess their effectiveness. We have grouped state-of-the-art deep anomaly detection research techniques into different categories based on the underlying assumptions and approach adopted. Within each category, we outline the basic anomaly detection technique, along with its variants and present key assumptions, to differentiate between normal and anomalous behavior. Besides, for each category, we also present the advantages and limitations and discuss the computational complexity of the techniques inreal application domains. Finally, we outline open issues in research and challenges faced while adopting deep anomaly detection techniques for real-world problems.

Toyota today revealed some of the inner workings of an automation package meant to help drivers rather than replace them. The company also said that if that package had been in operation, it could have prevented or mitigated a recent three-car accident in California. The announcement came at CES 2019, which takes place this week in Las Vegas. Toyota has often spoken of its two-stage research project for self-driving cars. In the long run, it plans to offer a truly driverless technology called Chauffeur.

This research aims to identify how Bitcoin-related news publications and online discourse are expressed in Bitcoin exchange movements of price and volume. Being inherently digital, all Bitcoin-related fundamental data (from exchanges, as well as transactional data directly from the blockchain) is available online, something that is not true for traditional businesses or currencies traded on exchanges. This makes Bitcoin an interesting subject for such research, as it enables the mapping of sentiment to fundamental events that might otherwise be inaccessible. Furthermore, Bitcoin discussion largely takes place on online forums and chat channels. In stock trading, the value of sentiment data in trading decisions has been demonstrated numerous times [1] [2] [3], and this research aims to determine whether there is value in such data for Bitcoin trading models. To achieve this, data over the year 2015 has been collected from Bitcointalk.org, (the biggest Bitcoin forum in post volume), established news sources such as Bloomberg and the Wall Street Journal, the complete /r/btc and /r/Bitcoin subreddits, and the bitcoin-otc and bitcoin-dev IRC channels. By analyzing this data on sentiment and volume, we find weak to moderate correlations between forum, news, and Reddit sentiment and movements in price and volume from 1 to 5 days after the sentiment was expressed. A Granger causality test confirms the predictive causality of the sentiment on the daily percentage price and volume movements, and at the same time underscores the predictive causality of market movements on sentiment expressions in online communities

Towards a Near Universal Time Series Data Mining Tool: Introducing the Matrix Profile by Chin-Chia Michael Yeh Doctor of Philosophy, Graduate Program in Computer Science University of California, Riverside, September 2018 Dr. Eamonn Keogh, Chairperson The last decade has seen a flurry of research on all-pairs-similarity-search (or, self-join) for text, DNA, and a handful of other datatypes, and these systems have been applied to many diverse data mining problems. Surprisingly, however, little progress has been made on addressing this problem for time series subsequences. In this thesis, we have introduced a near universal time series data mining tool called matrix profile which solves the all-pairssimilarity-search problem and caches the output in an easy-to-access fashion. The proposed algorithm is not only parameter-free, exact and scalable, but also applicable for both single and multidimensional time series. By building time series data mining methods on top of matrix profile, many time series data mining tasks (e.g., motif discovery, discord discovery, shapelet discovery, semantic segmentation, and clustering) can be efficiently solved. Because the same matrix profile can be shared by a diverse set of time series data mining methods, matrix profile is versatile and computed-once-use-many-times data structure. We demonstrate the utility of matrix profile for many time series data mining problems, including motif discovery, discord discovery, weakly labeled time series classification, and vi representation learning on domains as diverse as seismology, entomology, music processing, bioinformatics, human activity monitoring, electrical power-demand monitoring, and medicine. We hope the matrix profile is not the end but the beginning of many more time series data mining projects.

Unmanned Aerial Vehicles (UAVs) have recently rapidly grown to facilitate a wide range of innovative applications that can fundamentally change the way cyber-physical systems (CPSs) are designed. CPSs are a modern generation of systems with synergic cooperation between computational and physical potentials that can interact with humans through several new mechanisms. The main advantages of using UAVs in CPS application is their exceptional features, including their mobility, dynamism, effortless deployment, adaptive altitude, agility, adjustability, and effective appraisal of real-world functions anytime and anywhere. Furthermore, from the technology perspective, UAVs are predicted to be a vital element of the development of advanced CPSs. Therefore, in this survey, we aim to pinpoint the most fundamental and important design challenges of multi-UAV systems for CPS applications. We highlight key and versatile aspects that span the coverage and tracking of targets and infrastructure objects, energy-efficient navigation, and image analysis using machine learning for fine-grained CPS applications. Key prototypes and testbeds are also investigated to show how these practical technologies can facilitate CPS applications. We present and propose state-of-the-art algorithms to address design challenges with both quantitative and qualitative methods and map these challenges with important CPS applications to draw insightful conclusions on the challenges of each application. Finally, we summarize potential new directions and ideas that could shape future research in these areas.

AI will change radiology, but it won't replace radiologists.

Cyber attacks are growing in frequency and severity. Over the past year alone we have witnessed massive data breaches that stole personal information of millions of people and wide-scale ransomware attacks that paralyzed critical infrastructure of several countries. Combating the rising cyber threat calls for a multi-pronged strategy, which includes predicting when these attacks will occur. The intuition driving our approach is this: during the planning and preparation stages, hackers leave digital traces of their activities on both the surface web and dark web in the form of discussions on platforms like hacker forums, social media, blogs and the like. These data provide predictive signals that allow anticipating cyber attacks. In this paper, we describe machine learning techniques based on deep neural networks and autoregressive time series models that leverage external signals from publicly available Web sources to forecast cyber attacks. Performance of our framework across ground truth data over real-world forecasting tasks shows that our methods yield a significant lift or increase of F1 for the top signals on predicted cyber attacks. Our results suggest that, when deployed, our system will be able to provide an effective line of defense against various types of targeted cyber attacks.