Labeling or classifying time series is a persistent challenge in the physical sciences, where expert annotations are scarce, costly, and often inconsistent. Yet robust labeling is essential to enable machine learning models for understanding, prediction, and forecasting. We present the \textit{Clustering and Indexation Pipeline with Human Evaluation for Recognition} (CIPHER), a framework designed to accelerate large-scale labeling of complex time series in physics. CIPHER integrates \textit{indexable Symbolic Aggregate approXimation} (iSAX) for interpretable compression and indexing, density-based clustering (HDBSCAN) to group recurring phenomena, and a human-in-the-loop step for efficient expert validation. Representative samples are labeled by domain scientists, and these annotations are propagated across clusters to yield systematic, scalable classifications. We evaluate CIPHER on the task of classifying solar wind phenomena in OMNI data, a central challenge in space weather research, showing that the framework recovers meaningful phenomena such as coronal mass ejections and stream interaction regions. Beyond this case study, CIPHER highlights a general strategy for combining symbolic representations, unsupervised learning, and expert knowledge to address label scarcity in time series across the physical sciences. The code and configuration files used in this study are publicly available to support reproducibility.

Representation learning is increasingly applied to generate representations that generalize well across multiple downstream tasks. Ensuring fairness guarantees in representation learning is crucial to prevent unfairness toward specific demographic groups in downstream tasks. In this work, we formally introduce the task of learning representations that achieve high-confidence fairness. We aim to guarantee that demographic disparity in every downstream prediction remains bounded by a *user-defined* error threshold $ε$, with *controllable* high probability. To this end, we propose the ***F**air **R**epresentation learning with high-confidence **G**uarantees (FRG)* framework, which provides these high-confidence fairness guarantees by leveraging an optimized adversarial model. We empirically evaluate FRG on three real-world datasets, comparing its performance to six state-of-the-art fair representation learning methods. Our results demonstrate that FRG consistently bounds unfairness across a range of downstream models and tasks.

Generative AI tools are increasingly used to create portrayals of people in occupations, raising concerns about how race and gender are represented. We conducted a large-scale audit of over 1.5 million occupational personas across 41 U.S. occupations, generated by four large language models with different AI safety commitments and countries of origin (U.S., China, France). Compared with Bureau of Labor Statistics data, we find two recurring patterns: systematic shifts, where some groups are consistently under- or overrepresented, and stereotype exaggeration, where existing demographic skews are amplified. On average, White (--31pp) and Black (--9pp) workers are underrepresented, while Hispanic (+17pp) and Asian (+12pp) workers are overrepresented. These distortions can be extreme: for example, across all four models, Housekeepers are portrayed as nearly 100\% Hispanic, while Black workers are erased from many occupations. For HCI, these findings show provider choice materially changes who is visible, motivating model-specific audits and accountable design practices.

In response to the increasingly critical demand for accurate prediction of GPU memory resources in deep learning tasks, this paper deeply analyzes the current research status and innovatively proposes a deep learning model that integrates bidirectional gated recurrent units (BiGRU) to optimize the Transformer architecture, aiming to improve the accuracy of memory demand prediction. To verify the effectiveness of the model, a carefully designed comparative experiment was conducted, selecting four representative basic machine learning models: decision tree, random forest, Adaboost, and XGBoost as benchmarks. The detailed experimental results show that the BiGRU Transformer optimization model proposed in this paper exhibits significant advantages in key evaluation indicators: in terms of mean square error (MSE) and root mean square error (RMSE), the model achieves the lowest value among all comparison models, and its predicted results have the smallest deviation from the actual values; In terms of mean absolute error (MAE) and coefficient of determination (R2) indicators, the model also performs well and the results are balanced and stable, with comprehensive predictive performance far exceeding the benchmark machine learning methods compared. In summary, the Transformer model based on bidirectional gated recurrent unit optimization successfully constructed in this study can efficiently and accurately complete GPU memory demand prediction tasks in deep learning tasks, and its prediction accuracy has been significantly improved compared to traditional machine learning methods. This research provides strong technical support and reliable theoretical basis for optimizing resource scheduling and management of deep learning tasks, and improving the utilization efficiency of computing clusters.

Large language models have demonstrated remarkable reasoning capabilities across diverse natural language tasks. However, comparable breakthroughs in scientific discovery are more limited, because understanding complex physical phenomena demands multifaceted representations far beyond language alone. A compelling example is the design of functional materials such as MOFs-critical for a range of impactful applications like carbon capture and hydrogen storage. Navigating their vast and intricate design space in language-based representations interpretable by LLMs is challenging due to the numerous possible three-dimensional atomic arrangements and strict reticular rules of coordination geometry and topology. Despite promising early results in LLM-assisted discovery for simpler materials systems, MOF design remains heavily reliant on tacit human expertise rarely codified in textual information alone. To overcome this barrier, we introduce L2M3OF, the first multimodal LLM for MOFs. L2M3OF integrates crystal representation learning with language understanding to process structural, textual, and knowledge modalities jointly. L2M3OF employs a pre-trained crystal encoder with a lightweight projection layer to compress structural information into a token space, enabling efficient alignment with language instructions. To facilitate training and evaluation, we curate a structure-property-knowledge database of crystalline materials and benchmark L2M3OF against state-of-the-art closed-source LLMs such as GPT-5, Gemini-2.5-Pro and DeepSeek-R1. Experiments show that L2M3OF outperforms leading text-based closed-source LLMs in property prediction and knowledge generation tasks, despite using far fewer parameters. These results highlight the importance of multimodal approaches for porous material understanding and establish L2M3OF as a foundation for next-generation AI systems in materials discovery.

Reverse engineering (RE) of x86 binaries is indispensable for malware and firmware analysis, but remains slow due to stripped metadata and adversarial obfuscation. Large Language Models (LLMs) offer potential for improving RE efficiency through automated comprehension and commenting, but cloud-hosted, closed-weight models pose privacy and security risks and cannot be used in closed-network facilities. We evaluate parameter-efficient fine-tuned local LLMs for assisting with x86 RE tasks in these settings. Eight open-weight models across the CodeLlama, Qwen2.5-Coder, and CodeGemma series are fine-tuned on a custom curated dataset of 5,981 x86 assembly examples. We evaluate them quantitatively and identify the fine-tuned Qwen2.5-Coder-7B as the top performer, which we name REx86. REx86 reduces test-set cross-entropy loss by 64.2% and improves semantic cosine similarity against ground truth by 20.3\% over its base model. In a limited user case study (n=43), REx86 significantly enhanced line-level code understanding (p = 0.031) and increased the correct-solve rate from 31% to 53% (p = 0.189), though the latter did not reach statistical significance. Qualitative analysis shows more accurate, concise comments with fewer hallucinations. REx86 delivers state-of-the-art assistance in x86 RE among local, open-weight LLMs. Our findings demonstrate the value of domain-specific fine-tuning, and highlight the need for more commented disassembly data to further enhance LLM performance in RE. REx86, its dataset, and LoRA adapters are publicly available at https://github.com/dlea8/REx86 and https://zenodo.org/records/15420461.

Current Vision-Language Models (VLMs) struggle to ground anatomical regions in 3D medical images and reason about them in a step-by-step manner, a key requirement of real-world diagnostic assessment. This ability is essential for aligning model outputs with the diagnostic workflows clinicians use in practice, enabling trustworthy clinician-AI collaboration. Existing 3D datasets provide localization labels, but none support this "grounded reasoning" ability. To address this gap, we introduce 3DReasonKnee, the first 3D grounded reasoning dataset for medical images, which provides 494k high-quality quintuples derived from 7,970 3D knee MRI volumes. Each quintuple includes: (1) the 3D MRI volume, (2) a diagnostic question targeting a specific anatomical region (3) a 3D bounding box localizing the relevant anatomical structures, (4) clinician-generated diagnostic reasoning steps that explicitly detail the 3D reasoning process, and (5) structured severity assessments for the relevant anatomical region. The creation and validation of 3DReasonKnee, involving over 450 hours of expert clinician time for manually segmenting MRIs and generating reasoning chains, ensures its superior quality and clinical relevance. We establish ReasonKnee-Bench to evaluate localization and diagnostic accuracy, providing insight into VLM ability to perform grounding and severity assessment across anatomical regions and diagnostic inquiries. We benchmark five state-of-the-art VLMs, providing baseline performance for ReasonKnee-Bench. By providing this unique resource of expert-annotated 3D reasoning pathways, 3DReasonKnee serves as a repository of orthopedic surgeons' diagnostic expertise and offers a vital testbed for advancing multimodal medical AI systems towards 3D, clinically aligned, localized decision-making capabilities. The dataset can be found in: https://huggingface.co/datasets/rajpurkarlab/3DReasonKnee

Robotic suturing is a prototypical long-horizon dexterous manipulation task, requiring coordinated needle grasping, precise tissue penetration, and secure knot tying. Despite numerous efforts toward end-to-end autonomy, a fully autonomous suturing pipeline has yet to be demonstrated on physical hardware. We introduce SutureBot: an autonomous suturing benchmark on the da Vinci Research Kit (dVRK), spanning needle pickup, tissue insertion, and knot tying. To ensure repeatability, we release a high-fidelity dataset comprising 1,890 suturing demonstrations. Furthermore, we propose a goal-conditioned framework that explicitly optimizes insertion-point precision, improving targeting accuracy by 59\%-74\% over a task-only baseline. To establish this task as a benchmark for dexterous imitation learning, we evaluate state-of-the-art vision-language-action (VLA) models, including $π_0$, GR00T N1, OpenVLA-OFT, and multitask ACT, each augmented with a high-level task-prediction policy. Autonomous suturing is a key milestone toward achieving robotic autonomy in surgery. These contributions support reproducible evaluation and development of precision-focused, long-horizon dexterous manipulation policies necessary for end-to-end suturing. Dataset is available at: https://huggingface.co/datasets/jchen396/suturebot

Abstract--Falls among elderly and disabled individuals remain a leading cause of injury and mortality worldwide, necessitating robust, accurate, and privacy-aware fall detection systems. Traditional fall detection approaches, whether centralized or point-wise, often struggle with key challenges such as limited gener-alizability, data privacy concerns, and variability in individual movement behaviors. T o address these limitations, we propose EPFL--an Ensembled Penalized Federated Learning framework that integrates continual learning, personalized modeling, and a novel Specialized Weighted Aggregation (SW A) strategy. EPFL leverages wearable sensor data to capture sequential motion patterns while preserving user privacy through homomorphic encryption and federated training. Unlike existing federated models, EPFL incorporates both penalized local training and ensemble-based inference to improve inter-client consistency and adaptability to behavioral differences. Extensive experiments on a benchmark fall detection dataset demonstrate the effectiveness of our approach, achieving a Recall of 88.31% and an F1-score of 89.94%, significantly outperforming both centralized and baseline models. This work presents a scalable, secure, and accurate solution for real-world fall detection in healthcare settings, with strong potential for continuous improvement via its adaptive feedback mechanism. Due to changes in traditional family structures, the number of older individuals living alone has significantly increased over the past few decades [1]. According to the report from World Health Organization (WHO) [2], falls are the second leading cause of unintentional injury deaths worldwide, with particularly high morbidity among individuals aged 60 and older. Resulting in severe injuries, including fractures, head trauma, and even death, falls can significantly decline the quality of life of older adults [3]. Considering this, the need for effective monitoring and fall detection systems has been raised by this change aiming to ensure the safety of seniors. Falls can have long-term impacts on individuals, including significant disability-adjusted life years (DAL Ys) and high financial costs. According to the report [2], falls cause over 38 million DAL Ys lost annually worldwide. In Canada, a 20% reduction in falls could save approximately US$120 million each year. Considering the severe injuries, potential fatalities and other additional costs resulting from sudden falls [4], fall detection is a critical research area, especially for the elderly and individuals with disabilities.

We present Irish-BLiMP (Irish Benchmark of Linguistic Minimal Pairs), the first dataset and framework designed for fine-grained evaluation of linguistic competence in the Irish language, an endangered language. Drawing on a variety of linguistic literature and grammar reference works, we manually constructed and reviewed 1020 minimal pairs across a taxonomy of 11 linguistic features, through a team of fluent Irish speakers. We evaluate both existing Large Language Models (LLMs) and fluent human participants on their syntactic knowledge of Irish. Our findings show that humans outperform all models across all linguistic features, achieving 16.6% higher accuracy on average. Moreover, a substantial performance gap of 18.1% persists between open- and closed-source LLMs, with even the strongest model (gpt-5) reaching only 73.5% accuracy compared to 90.1% by human. Interestingly, human participants and models struggle on different aspects of Irish grammar, thus highlighting a difference in representation learned by the models. Overall, Irish-BLiMP provides the first systematic framework for evaluating the grammatical competence of LLMs in Irish and offers a valuable benchmark for advancing research on linguistic understanding in low-resource languages.