AI components are increasingly becoming a key element of all types of software systems to enhance their functionality. These AI components are often implemented as AI Agents, offering more autonomy than a plain integration of Large Language Models (LLMs), moving from a Model-as-a-Service paradigm to an Agent-as-a-Service one, bringing new challenges to the development of smart software systems. Indeed, while support for the design, implementation, and deployment of those agents exist, the specification of Quality of Service (QoS) and definition of Service Level Agreements (SLAs) aspects for those agents, important to ensure the quality of the resulting systems, remains an open challenge. Part of this is due to the difficulty to clearly define quality in the context of AI components, resulting in a lack of consensus on how to best approach Quality Assurance (QA) for these types of systems. To address this challenge, this paper proposes both a quality model for AI agents based on the ISO/IEC 25010 standard, and a domain specific language to support the definition of SLAs for the services provided by these AI agents.

While prior work on group recommender systems (GRSs) has primarily focused on improving recommendation accuracy, most approaches assume static or predefined groups, making them unsuitable for dynamic, real-world scenarios. We reframe group formation as a core challenge in GRSs and propose DeepForm (Stochastic Deep Graph Clustering for Practical Group Formation), a framework designed to meet three key operational requirements: (1) the incorporation of high-order user information, (2) real-time group formation, and (3) dynamic adjustment of the number of groups. DeepForm employs a lightweight GCN architecture that effectively captures high-order structural signals. Stochastic cluster learning enables adaptive group reconfiguration without retraining, while contrastive learning refines groups under dynamic conditions. Experiments on multiple datasets demonstrate that DeepForm achieves superior group formation quality, efficiency, and recommendation accuracy compared with various baselines.

As generative AI diffuses through academia, policy-practice divergence becomes consequential, creating demand for auditable indicators of alignment. This study prototypes a ten-item, indirect-elicitation instrument embedded in a structured interpretive framework to surface voids between institutional rules and practitioner AI use. The framework extracts empirical and epistemic signals from academics, yielding three filtered indicators of such voids: (1) AI-integrated assessment capacity (proxy) - within a three-signal screen (AI skill, perceived teaching benefit, detection confidence), the share who would fully allow AI in exams; (2) sector-level necessity (proxy) - among high output control users who still credit AI with high contribution, the proportion who judge AI capable of challenging established disciplines; and (3) ontological stance - among respondents who judge AI different in kind from prior tools, report practice change, and pass a metacognition gate, the split between material and immaterial views as an ontological map aligning procurement claims with evidence classes.

Abstract--Blockchain systems face persistent challenges of scalability, latency, and energy inefficiency. Existing consensus protocols such as Proof-of-Work (PoW) and Proof-of-Stake (PoS) either consume excessive resources or risk centralization. This paper proposes Proof-of-Spiking-Neurons (PoSN), a neuromor-phic consensus protocol inspired by spiking neural networks. A hybrid system architecture is implemented on neuromorphic platforms, supported by simulation frameworks such as Nengo and PyNN. Experimental results show significant gains in energy efficiency, throughput, and convergence compared to PoB and PoR. PoSN establishes a foundation for sustainable, adaptive blockchains suitable for IoT, edge, and large-scale distributed systems. Index T erms--Blockchain consensus, Neuromorphic computing, Distributed ledger technology.

Abstract--Bit-flip attacks threaten the reliability and security of Language Models (LMs) by altering internal parameters and compromising output integrity. Recent studies show that flipping only a few bits in model parameters can bypass safety mechanisms and jailbreak the model. Existing detection approaches for DNNs and CNNs are not suitable for LMs, as the massive number of parameters significantly increases timing and memory overhead for software-based methods and chip area overhead for hardware-based methods. In this work, we present LM-Fix, a lightweight LM-driven detection and recovery framework that leverages the model's own capabilities to identify and recover faults. Our method detects bit-flips by generating a single output token from a predefined test vector and auditing the output tensor of a target layer against stored reference data. The same mechanism enables rapid recovery without reloading the entire model. Experiments across various models show that LM-Fix detects more than 94% of single-bit flips and nearly 100% of multi-bit flips, with very low computational overhead ( 1%- 7.7% at TVL = 200 across models). Recovery achieves more than 100 speedup compared to full-model reload, which is critical in edge devices. LM-Fix can handle bit-flips affecting any part of the model's computation, including memory, cache, and arithmetic operations. Evaluation against recent LM-specific bit-flip attacks confirms its robustness and practical value for real-world deployment.

School of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China # These authors contributed equally to this work. Email: andrewxiao@bupt.edu.cn;liuliqing@ibp.ac.cn;huj@ibp.ac.cn; feisun@ibp.ac.cn; yangge@ucas.edu.cn;xutao@ibp.ac.cn ABSTRACT Recent advances in 2D large - scale and 3D volume electron microscopy have stimulated the rapid development of nanoscale functional analysis at the tissue and organ levels. To meet the requirements of characterizing intracellular organelle s and their interactions within defined cellular cohorts at tissue level, we have developed DeepOrganelle. It adopts a lightweighted Mask2Former frameworks as a universal segmentor and is capable of segmenting and extracting organelles within different cell types, performing statistical quantitative analysis, as well as visualizing and quantifying the spatial distribution of organelle morphologies and interactions across different cell types at tissue scales. Using DeepOrganelle, we systemically perform cross - scale quantification of membrane contact sites( MCSs) dynamics across the progression of the seminiferous epithelial cycle, covering 12 distinct developmental stages and 24 statuses of germ cells . Noticeably, it discovers a waved pattern of mitochondria(Mito) - endoplasmic reticulum(ER) contact with a significant increase specifically at Stage X pachytene preceding the transition to diplotene, which aligns well with a newly reported experiment that mitochondrial metabolic proteins like PDHA2 are essential for this transition by maintaining ATP supply for double - strand break (DSB) repair.

Conscious state estimation is important in various medical settings, including sleep staging and anesthesia management, to ensure patient safety and optimize health outcomes. Traditional methods predominantly utilize electroencephalography (EEG), which faces challenges such as high sensitivity to noise and the requirement for controlled environments. In this study, we propose the consciousness-ECG transformer that leverages electrocardiography (ECG) signals for non-invasive and reliable conscious state estimation. Our approach employs a transformer with decoupled query attention to effectively capture heart rate variability features that distinguish between conscious and unconscious states. We implemented the conscious state estimation system with real-time monitoring and validated our system on datasets involving sleep staging and anesthesia level monitoring during surgeries. Experimental results demonstrate that our model outperforms baseline models, achieving accuracies of 0.877 on sleep staging and 0.880 on anesthesia level monitoring. Moreover, our model achieves the highest area under curve values of 0.786 and 0.895 on sleep staging and anesthesia level monitoring, respectively. The proposed system offers a practical and robust alternative to EEG-based methods, particularly suited for dynamic clinical environments. Our results highlight the potential of ECG-based consciousness monitoring to enhance patient safety and advance our understanding of conscious states.

Deploying advanced cardiac artificial intelligence for daily cardiac monitoring is hindered by its reliance on extensive medical data and high computational resources. Low-cost cardiac intelligence (LCCI) offers a promising alternative by using wearable device data, such as 1-lead electrocardiogram (ECG), but it suffers from a significant diagnostic performance gap compared to high-cost cardiac intelligence (HCCI). To bridge this gap, we propose LiteHeart, a semi-supervised knowledge distillation framework. LiteHeart introduces a region-aware distillation module to mimic how cardiologists focus on diagnostically relevant ECG regions and a cross-layer mutual information module to align the decision processes of LCCI and HCCI systems. Using a semi-supervised training strategy, LiteHeart further improves model robustness under limited supervision. Evaluated on five datasets covering over 38 cardiovascular diseases, LiteHeart substantially reduces the performance gap between LCCI and HCCI, outperforming existing methods by 4.27% to 7.10% in macro F1 score. These results demonstrate that LiteHeart significantly enhances the diagnostic capabilities of low-cost cardiac intelligence systems, paving the way for scalable, affordable, and accurate daily cardiac healthcare using wearable technologies.

This paper presents ECGXtract, a deep learning-based approach for interpretable ECG feature extraction, addressing the limitations of traditional signal processing and black-box machine learning methods. In particular, we develop convolutional neural network models capable of extracting both temporal and morphological features with strong correlations to a clinically validated ground truth. Initially, each model is trained to extract a single feature, ensuring precise and interpretable outputs. A series of experiments is then carried out to evaluate the proposed method across multiple setups, including global versus lead-specific features, different sampling frequencies, and comparisons with other approaches such as ECGdeli. Our findings show that ECGXtract achieves robust performance across most features with a mean correlation score of 0.80 with the ground truth for global features, with lead II consistently providing the best results. For lead-specific features, ECGXtract achieves a mean correlation score of 0.822. Moreover, ECGXtract achieves superior results to the state-of-the-art open source ECGdeli as it got a higher correlation score with the ground truth in 90% of the features. Furthermore, we explore the feasibility of extracting multiple features simultaneously utilizing a single model. Semantic grouping is proved to be effective for global features, while large-scale grouping and lead-specific multi-output models show notable performance drops. These results highlight the potential of structured grouping strategies to balance the computational efficiency vs. model accuracy, paving the way for more scalable and clinically interpretable ECG feature extraction systems in limited resource settings.

Electroencephalography (EEG) is a widely used non-invasive technique for monitoring brain activity, but low signal-to-noise ratios (SNR) due to various artifacts often compromise its utility. Conventional artifact removal methods require manual intervention or risk suppressing critical neural features during filtering/reconstruction. Recent advances in generative models, including Variational Autoencoders (VAEs) and Generative Adversarial Networks (GANs), have shown promise for EEG reconstruction; however, these approaches often lack integrated temporal-spectral-spatial sensitivity and are computationally intensive, limiting their suitability for real-time applications like brain-computer interfaces (BCIs). To overcome these challenges, we introduce EEGReXferNet, a lightweight Gen-AI framework for EEG subspace reconstruction via cross-subject transfer learning - developed using Keras TensorFlow (v2.15.1). EEGReXferNet employs a modular architecture that leverages volume conduction across neighboring channels, band-specific convolution encoding, and dynamic latent feature extraction through sliding windows. By integrating reference-based scaling, the framework ensures continuity across successive windows and generalizes effectively across subjects. This design improves spatial-temporal-spectral resolution (mean PSD correlation >= 0.95; mean spectrogram RV-Coefficient >= 0.85), reduces total weights by ~45% to mitigate overfitting, and maintains computational efficiency for robust, real-time EEG preprocessing in neurophysiological and BCI applications.