The resource demands of deep neural network (DNN) models introduce significant performance challenges, especially when deployed on resource-constrained edge devices. Existing solutions like model compression often sacrifice accuracy, while specialized hardware remains costly and inflexible. Hybrid inference methods, however, typically overlook how operator characteristics impact performance. In this work, we present SparOA, a CPU-GPU hybrid inference framework, which leverages both sparsity and computational intensity to optimize operator scheduling. SparOA embraces aforementioned challenges through three key components: (1) a threshold predictor that accurately determines optimal sparsity and computational intensity thresholds; (2) a reinforcement learning-based scheduler that dynamically optimizes resource allocation based on real-time hardware states; and (3) a hybrid inference engine that enhances efficiency through asynchronous execution and batch size optimization.Extensive results show that SparOA achieves an average speedup of 1.22-1.31x compared to all baselines, and outperforms the CPU-Only by up to 50.7x. Also, SparOA achieves optimal energy-per-inference, consuming 7\%-16\% less energy than the SOTA co-execution baseline.

Autonomous vehicles (AVs) are evolving into mobile computing platforms, equipped with powerful processors and diverse sensors that generate massive heterogeneous data, for example 14 TB per day. Supporting emerging third-party applications calls for a general-purpose, queryable onboard storage system. Yet today's data loggers and storage stacks in vehicles fail to deliver efficient data storage and retrieval. This paper presents AVS, an Autonomous Vehicle Storage system that co-designs computation with a hierarchical layout: modality-aware reduction and compression, hot-cold tiering with daily archival, and a lightweight metadata layer for indexing. The design is grounded with system-level benchmarks on AV data that cover SSD and HDD filesystems and embedded indexing, and is validated on embedded hardware with real L4 autonomous driving traces. The prototype delivers predictable real-time ingest, fast selective retrieval, and substantial footprint reduction under modest resource budgets. The work also outlines observations and next steps toward more scalable and longer deployments to motivate storage as a first-class component in AV stacks.

Inter-agent communication serves as an effective mechanism for enhancing performance in collaborative multi-agent reinforcement learning(MARL) systems. However, the inherent communication latency in practical systems induces both action decision delays and outdated information sharing, impeding MARL performance gains, particularly in time-critical applications like autonomous driving. In this work, we propose a V alue-of-Information aware Low-latency Communication(VIL2C) scheme that proactively adjusts the latency distribution to mitigate its effects in MARL systems. Specifically, we define a V alue of Information (VOI) metric to quantify the importance of delayed message transmission based on each delayed message's importance. Moreover, we propose a progressive message reception mechanism to adap-tively adjust the reception duration based on received messages. We derive the optimized V oI aware resource allocation and theoretically prove the performance advantage of the proposed VIL2C scheme. Extensive experiments demonstrate that VIL2C outperforms existing approaches under various communication conditions. These gains are attributed to the low-latency transmission of high-V oI messages via resource allocation and the elimination of unnecessary waiting periods via adaptive reception duration.

As graph-structured data grow increasingly large, evaluating their robustness under adversarial attacks becomes computationally expensive and difficult to scale. To address this challenge, we propose to compress graphs into compact representations that preserve both topological structure and robustness profile, enabling efficient and reliable evaluation. We propose Cutter, a dual-agent reinforcement learning framework composed of a Vital Detection Agent (VDA) and a Redundancy Detection Agent (RDA), which collaboratively identify structurally vital and redundant nodes for guided compression. Cutter incorporates three key strategies to enhance learning efficiency and compression quality: trajectory-level reward shaping to transform sparse trajectory returns into dense, policy-equivalent learning signals; prototype-based shaping to guide decisions using behavioral patterns from both high- and low-return trajectories; and cross-agent imitation to enable safer and more transferable exploration. Experiments on multiple real-world graphs demonstrate that Cutter generates compressed graphs that retain essential static topological properties and exhibit robustness degradation trends highly consistent with the original graphs under various attack scenarios, thereby significantly improving evaluation efficiency without compromising assessment fidelity.

Retrieval-augmented generation (RAG) enables large language models (LLMs) to access external knowledge, helping mitigate hallucinations and enhance domain-specific expertise. Graph-based RAG enhances structural reasoning by introducing explicit relational organization that enables information propagation across semantically connected text units. However, these methods typically rely on Euclidean embeddings that capture semantic similarity but lack a geometric notion of hierarchical depth, limiting their ability to represent abstraction relationships inherent in complex knowledge graphs. To capture both fine-grained semantics and global hierarchy, we propose HyperbolicRAG, a retrieval framework that integrates hyperbolic geometry into graph-based RAG. HyperbolicRAG introduces three key designs: (1) a depth-aware representation learner that embeds nodes within a shared Poincare manifold to align semantic similarity with hierarchical containment, (2) an unsupervised contrastive regularization that enforces geometric consistency across abstraction levels, and (3) a mutual-ranking fusion mechanism that jointly exploits retrieval signals from Euclidean and hyperbolic spaces, emphasizing cross-space agreement during inference. Extensive experiments across multiple QA benchmarks demonstrate that HyperbolicRAG outperforms competitive baselines, including both standard RAG and graph-augmented baselines.

AutoFocus-IL is a simple yet effective method to improve data efficiency and generalization in visual imitation learning by guiding policies to attend to task-relevant features rather than distractors and spurious correlations. Although saliency regularization has emerged as a promising way to achieve this, existing approaches typically require costly supervision such as human gaze data or manual saliency annotations. In contrast, AutoFocus-IL leverages vision-language models (VLMs) to automatically identify and track key objects in demonstrations, generating temporal saliency maps that highlight causal visual signals while suppressing distractors. These maps are then used to regularize behavior cloning policies, yielding stronger alignment between visual attention and task-relevant cues. Experiments in both the CARLA simulator and real-robot manipulation tasks demonstrate that AutoFocus-IL not only outperforms standard behavior cloning but also surpasses state-of-the-art baselines that assume privileged access to human supervision, such as gaze data. Code, datasets, and trained policy videos are available at https://AutoFocus-IL.github.io/.

The substantial diversity in cell scale and form remains a primary challenge in computer-aided cancer detection on gigapixel Whole Slide Images (WSIs), attributable to cellular heterogeneity. Existing CNN-Transformer hybrids rely on static computation graphs with fixed routing, which consequently causes redundant computation and limits their adaptability to input variability. We propose Shape-Adapting Gated Experts (SAGE), an input-adaptive framework that enables dynamic expert routing in heterogeneous visual networks. SAGE reconfigures static backbones into dynamically routed expert architectures. SAGE's dual-path design features a backbone stream that preserves representation and selectively activates an expert path through hierarchical gating. This gating mechanism operates at multiple hierarchical levels, performing a two-level, hierarchical selection between shared and specialized experts to modulate model logits for Top-K activation. Our Shape-Adapting Hub (SA-Hub) harmonizes structural and semantic representations across the CNN and the Transformer module, effectively bridging diverse modules. Embodied as SAGE-UNet, our model achieves superior segmentation on three medical benchmarks: EBHI, DigestPath, and GlaS, yielding state-of-the-art Dice Scores of 95.57%, 95.16%, and 94.17%, respectively, and robustly generalizes across domains by adaptively balancing local refinement and global context. SAGE provides a scalable foundation for dynamic expert routing, enabling flexible visual reasoning.

Spatial Transcriptomics (ST) is a technology that measures gene expression profiles within tissue sections while retaining spatial context. It reveals localized gene expression patterns and tissue heterogeneity, both of which are essential for understanding disease etiology. However, its high cost has driven efforts to predict spatial gene expression from whole slide images. Despite recent advancements, current methods still face significant limitations, such as under-exploitation of high-level biological context, over-reliance on exemplar retrievals, and inadequate alignment of heterogeneous modalities. To address these challenges, we propose DKAN, a novel Dual-path Knowledge-Augmented contrastive alignment Network that predicts spatially resolved gene expression by integrating histopathological images and gene expression profiles through a biologically informed approach. Specifically, we introduce an effective gene semantic representation module that leverages the external gene database to provide additional biological insights, thereby enhancing gene expression prediction. Further, we adopt a unified, one-stage contrastive learning paradigm, seamlessly combining contrastive learning and supervised learning to eliminate reliance on exemplars, complemented with an adaptive weighting mechanism. Additionally, we propose a dual-path contrastive alignment module that employs gene semantic features as dynamic cross-modal coordinators to enable effective heterogeneous feature integration. Through extensive experiments across three public ST datasets, DKAN demonstrates superior performance over state-of-the-art models, establishing a new benchmark for spatial gene expression prediction and offering a powerful tool for advancing biological and clinical research.

Transformers have defined the state-of-the-art for clinical prediction tasks involving electronic health records (EHRs). The recently introduced Mamba architecture outperformed an advanced Transformer (Transformer++) based on Llama in handling long context lengths, while using fewer model parameters. Despite the impressive performance of these architectures, a systematic approach to empirically analyze model performance and efficiency under various settings is not well established in the medical domain. The performances of six sequence models were investigated across three architecture classes (Transformers, Transformers++, Mambas) in a large Swedish heart failure (HF) cohort (N = 42820), providing a clinically relevant case study. Patient data included diagnoses, vital signs, laboratories, medications and procedures extracted from in-hospital EHRs. The models were evaluated on three one-year prediction tasks: clinical instability (a readmission phenotype) after initial HF hospitalization, mortality after initial HF hospitalization and mortality after latest hospitalization. Ablations account for modifications of the EHR-based input patient sequence, architectural model configurations, and temporal preprocessing techniques for data collection. Llama achieves the highest predictive discrimination, best calibration, and showed robustness across all tasks, followed by Mambas. Both architectures demonstrate efficient representation learning, with tiny configurations surpassing other large-scaled Transformers. At equal model size, Llama and Mambas achieve superior performance using 25% less training data. This paper presents a first ablation study with systematic design choices for input tokenization, model configuration and temporal data preprocessing. Future model development in clinical prediction tasks using EHRs could build upon this study's recommendation as a starting point.

The AI trustworthiness crisis threatens to derail the artificial intelligence revolution, with regulatory barriers, security vulnerabilities, and accountability gaps preventing deployment in critical domains. Current AI systems operate on opaque data structures that lack the audit trails, provenance tracking, or explainability required by emerging regulations like the EU AI Act. We propose an artifact-centric AI agent paradigm where behavior is driven by persistent, verifiable data artifacts rather than ephemeral tasks, solving the trustworthiness problem at the data architecture level. Central to this approach is the Multimodal Artifact File Format (MAIF), an AI-native container embedding semantic representations, cryptographic provenance, and granular access controls. MAIF transforms data from passive storage into active trust enforcement, making every AI operation inherently auditable. Our production-ready implementation demonstrates ultra-high-speed streaming (2,720.7 MB/s), optimized video processing (1,342 MB/s), and enterprise-grade security. Novel algorithms for cross-modal attention, semantic compression, and cryptographic binding achieve up to 225 compression while maintaining semantic fidelity. Advanced security features include stream-level access control, real-time tamper detection, and behavioral anomaly analysis with minimal overhead. This approach directly addresses the regulatory, security, and accountability challenges preventing AI deployment in sensitive domains, offering a viable path toward trustworthy AI systems at scale.