Accurate medical diagnosis often involves progressive visual focusing and iterative reasoning, characteristics commonly observed in clinical workflows. While recent vision-language models demonstrate promising chain-of-thought (CoT) reasoning capabilities via reinforcement learning with verifiable rewards (RLVR), their purely on-policy learning paradigm tends to reinforce superficially coherent but clinically inaccurate reasoning paths. We propose MedEyes, a novel reinforcement learning framework that dynamically models clinician-style diagnostic reasoning by progressively attending to and interpreting relevant medical image regions. By incorporating off-policy expert guidance, MedEyes converts expert visual search trajectories into structured external behavioral signals, guiding the model toward clinically aligned visual reasoning. We design the Gaze-guided Reasoning Navigator (GRN) to emulate the diagnostic process through a dual-mode exploration strategy, scanning for systematic abnormality localization and drilling for detailed regional analysis. To balance expert imitation and autonomous discovery, we introduce the Confidence Value Sampler (CVS), which employs nucleus sampling and adaptive termination to create diverse yet credible exploration paths. Finally, the dual-stream GRPO optimization framework decouples on-policy and off-policy learning signals, mitigating reward assimilation and entropy collapse. Experiments demonstrate that MedEyes achieves an average performance improvement of +8.5\% across multiple medical VQA benchmarks, validating MedEyes's potential in building interpretable medical AI systems.

Existing AI bias evaluation benchmarks largely reflect Western perspectives, leaving African contexts underrepresented and enabling harmful stereotypes in applications across various domains. To address this gap, we introduce AfriStereo, the first open-source African stereotype dataset and evaluation framework grounded in local socio-cultural contexts. Through community engaged efforts across Senegal, Kenya, and Nigeria, we collected 1,163 stereotypes spanning gender, ethnicity, religion, age, and profession. Using few-shot prompting with human-in-the-loop validation, we augmented the dataset to over 5,000 stereotype-antistereotype pairs. Entries were validated through semantic clustering and manual annotation by culturally informed reviewers. Preliminary evaluation of language models reveals that nine of eleven models exhibit statistically significant bias, with Bias Preference Ratios (BPR) ranging from 0.63 to 0.78 (p <= 0.05), indicating systematic preferences for stereotypes over antistereotypes, particularly across age, profession, and gender dimensions. Domain-specific models appeared to show weaker bias in our setup, suggesting task-specific training may mitigate some associations. Looking ahead, AfriStereo opens pathways for future research on culturally grounded bias evaluation and mitigation, offering key methodologies for the AI community on building more equitable, context-aware, and globally inclusive NLP technologies.

Large vision foundation models have been widely adopted for retinal disease classification without systematic evidence justifying their parameter requirements. In the present work we address two critical questions: First, are large domain-specific foundation models essential, or do compact general-purpose architectures suffice? Second, does specialized retinal pretraining justify its computational cost? To answer this, we benchmark initialization strategies across four retinal imaging classification tasks spanning Optical Coherence Tomography (OCT) and Color Fundus Photography (CFP) modalities: 8-class OCT classification, 3-class diabetic macular edema (DME), 5-class diabetic retinopathy (DR), and 3-class glaucoma (GL) detection. We evaluate 12-13 model configurations per task, including vision transformers (22.8M-86.6M parameters), Swin Transformers (27.6M-28.3M), ConvNeXt (28.6M), and the domain-specific RETFound models (303M), under identical training conditions. Our results challenge prevailing assumptions: First, we demonstrate that pretraining provides universal benefits (5.18-18.41% improvement), scaling with task difficulty. Second, compact architectures (27-29M) dominate Pareto frontiers; SwinV2-tiny achieves top-1 performance on three datasets. Third, RETFound (303M) justifies its computational cost only for challenging DR grading (accuracy of 71.15%), while ImageNet pretraining proves to be sufficient with all other tasks (DME accuracy: 99.24%, OCT accuracy: 97.96%). CFP tasks show larger pretraining accuracy gains (9.13-18.41%) than OCT (5.18%). Thus, the evidence suggests that compact general-purpose models deliver near-optimal performance for most retinal classification tasks; specialized foundation models warranted only for fine-grained discrimination under extreme class imbalance.

Real-time sea state estimation is vital for applications like shipbuilding and maritime safety. Traditional methods rely on accurate wave-vessel transfer functions to estimate wave spectra from onboard sensors. In contrast, our approach jointly estimates sea state and vessel parameters without needing prior transfer function knowledge, which may be unavailable or variable. We model the wave-vessel system using pseudo mass-spring-dampers and develop a dynamic model for the system. This method allows for recursive modeling of wave excitation as a time-varying input, relaxing prior works' assumption of a constant input. We derive statistically consistent process noise covariance and implement a square root cubature Kalman filter for sensor data fusion. Further, we derive the Posterior Cramer-Rao lower bound to evaluate estimator performance. Extensive Monte Carlo simulations and data from a high-fidelity validated simulator confirm that the estimated wave spectrum matches methods assuming complete transfer function knowledge.

This paper introduces a dynamic and actionable framework for securing agentic AI systems in enterprise deployment. We contend that safety and security are not merely fixed attributes of individual models but also emergent properties arising from the dynamic interactions among models, orchestrators, tools, and data within their operating environments. We propose a new way of identification of novel agentic risks through the lens of user safety. Although, for traditional LLMs and agentic models in isolation, safety and security has a clear separation, through the lens of safety in agentic systems, they appear to be connected. Building on this foundation, we define an operational agentic risk taxonomy that unifies traditional safety and security concerns with novel, uniquely agentic risks, including tool misuse, cascading action chains, and unintended control amplification among others. At the core of our approach is a dynamic agentic safety and security framework that operationalizes contextual agentic risk management by using auxiliary AI models and agents, with human oversight, to assist in contextual risk discovery, evaluation, and mitigation. We further address one of the most challenging aspects of safety and security of agentic systems: risk discovery through sandboxed, AI-driven red teaming. We demonstrate the framework effectiveness through a detailed case study of NVIDIA flagship agentic research assistant, AI-Q Research Assistant, showcasing practical, end-to-end safety and security evaluations in complex, enterprise-grade agentic workflows. This risk discovery phase finds novel agentic risks that are then contextually mitigated. We also release the dataset from our case study, containing traces of over 10,000 realistic attack and defense executions of the agentic workflow to help advance research in agentic safety.

Digital Elevation Models (DEMs) are vital datasets for geospatial applications such as hydrological modeling and environmental monitoring. However, conventional methods to generate DEM, such as using LiDAR and photogrammetry, require specific types of data that are often inaccessible in resource-constrained settings. To alleviate this problem, this study proposes an approach to generate DEM from freely available RGB satellite imagery using generative deep learning, particularly based on a conditional Generative Adversarial Network (GAN). We first developed a global dataset consisting of 12K RGB-DEM pairs using Landsat satellite imagery and NASA's SRTM digital elevation data, both from the year 2000. A unique preprocessing pipeline was implemented to select high-quality, cloud-free regions and aggregate normalized RGB composites from Landsat imagery. Additionally, the model was trained in a two-stage process, where it was first trained on the complete dataset and then fine-tuned on high-quality samples filtered by Structural Similarity Index Measure (SSIM) values to improve performance on challenging terrains. The results demonstrate promising performance in mountainous regions, achieving an overall mean root-mean-square error (RMSE) of 0.4671 and a mean SSIM score of 0.2065 (scale -1 to 1), while highlighting limitations in lowland and residential areas. This study underscores the importance of meticulous preprocessing and iterative refinement in generative modeling for DEM generation, offering a cost-effective and adaptive alternative to conventional methods while emphasizing the challenge of generalization across diverse terrains worldwide.

Organizations investing in artificial intelligence face a fundamental challenge: traditional return on investment calculations fail to capture the dual nature of AI implementations, which simultaneously reduce certain operational risks while introducing novel exposures related to algorithmic malfunction, adversarial attacks, and regulatory liability. This research presents a comprehensive financial framework for quantifying AI project returns that explicitly integrates changes in organizational risk profiles. The methodology addresses a critical gap in current practice where investment decisions rely on optimistic benefit projections without accounting for the probabilistic costs of AI-specific threats including model drift, bias-related litigation, and compliance failures under emerging regulations such as the European Union Artificial Intelligence Act and ISO/IEC 42001. Drawing on established risk quantification methods, including annual loss expectancy calculations and Monte Carlo simulation techniques, this framework enables practitioners to compute net benefits that incorporate both productivity gains and the delta between pre-implementation and post-implementation risk exposures. The analysis demonstrates that accurate AI investment evaluation requires explicit modeling of control effectiveness, reserve requirements for algorithmic failures, and the ongoing operational costs of maintaining model performance. Practical implications include specific guidance for establishing governance structures, conducting phased validations, and integrating risk-adjusted metrics into capital allocation decisions, ultimately enabling evidence-based AI portfolio management that satisfies both fiduciary responsibilities and regulatory mandates.

This paper presents a systematic study on developing multi-template machine learning (ML) surrogate models and applying them to the inverse design of transformers (XFMRs) in radio-frequency integrated circuits (RFICs). Our study starts with benchmarking four widely used ML architectures, including MLP-, CNN-, UNet-, and GT-based models, using the same datasets across different XFMR topologies. To improve modeling accuracy beyond these baselines, we then propose a new frequency-domain self-transfer learning technique that exploits correlations between adjacent frequency bands, leading to around 30%-50% accuracy improvement in the S-parameters prediction. Building on these models, we further develop an inverse design framework based on the covariance matrix adaptation evolutionary strategy (CMA-ES) algorithm. This framework is validated using multiple impedance-matching tasks, all demonstrating fast convergence and trustworthy performance. These results advance the goal of AI-assisted specs-to-GDS automation for RFICs and provide RFIC designers with actionable tools for integrating AI into their workflows.

Click-through rates prediction is critical in modern advertising systems, where ranking relevance and user engagement directly impact platform efficiency and business value. In this project, we explore how to model CTR more effectively using a large-scale Taobao dataset released by Alibaba. We start with supervised learning models, including logistic regression and Light-GBM, that are trained on static features such as user demographics, ad attributes, and contextual metadata. These models provide fast, interpretable benchmarks, but have limited capabilities to capture patterns of behavior that drive clicks. To better model user intent, we combined behavioral data from hundreds of millions of interactions over a 22-day period. By extracting and encoding user action sequences, we construct representations of user interests over time. We use deep learning models to fuse behavioral embeddings with static features. Among them, multilayer perceptrons (MLPs) have achieved significant performance improvements. To capture temporal dynamics, we designed a Transformer-based architecture that uses a self-attention mechanism to learn contextual dependencies across behavioral sequences, modeling not only what the user interacts with, but also the timing and frequency of interactions. Transformer improves AUC by 2.81 % over the baseline (LR model), with the largest gains observed for users whose interests are diverse or change over time. In addition to modeling, we propose an A/B testing strategy for real-world evaluation. We also think about the broader implications: personalized ad targeting technology can be applied to public health scenarios to achieve precise delivery of health information or behavior guidance. Our research provides a roadmap for advancing click-through rate predictions and extending their value beyond e-commerce.

This paper presents a comprehensive comparative model analysis on a novel gastrointestinal medical imaging dataset, comprised of 4,000 endoscopic images spanning four critical disease classes: Diverticulosis, Neoplasm, Peritonitis, and Ureters. Leveraging state-of-the-art deep learning techniques, the study confronts common endoscopic challenges such as variable lighting, fluctuating camera angles, and frequent imaging artifacts. The best performing models, VGG16 and MobileNetV2, each achieved a test accuracy of 96.5%, while Xception reached 94.24%, establishing robust benchmarks and baselines for automated disease classification. In addition to strong classification performance, the approach includes explainable AI via Grad-CAM visualization, enabling identification of image regions most influential to model predictions and enhancing clinical interpretability. Experimental results demonstrate the potential for robust, accurate, and interpretable medical image analysis even in complex real-world conditions. This work contributes original benchmarks, comparative insights, and visual explanations, advancing the landscape of gastrointestinal computer-aided diagnosis and underscoring the importance of diverse, clinically relevant datasets and model explainability in medical AI research.