Current language model safety paradigms often fall short in emotionally charged or high-stakes settings, where refusal-only approaches may alienate users and naive compliance can amplify risk. We propose ProSocialAlign, a test-time, parameter-efficient framework that steers generation toward safe, empathetic, and value-aligned responses without retraining the base model. We formalize five human-centered objectives and cast safety as lexicographic constrained generation: first, applying hard constraints to eliminate harmful continuations; then optimizing for prosocial quality within the safe set. Our method combines (i) directional regulation, a harm-mitigation mechanism that subtracts a learned "harm vector" in parameter space, and (ii) preference-aware autoregressive reward modeling trained jointly across attributes with gradient conflict resolution, enabling fine-grained, user-controllable decoding. Empirical evaluations across five safety benchmarks demonstrate state-of-the-art performance, reducing unsafe leakage and boosting alignment to human values, with strong gains across multiple evaluation metrics. ProSocialAlign offers a robust and modular foundation for generating context-sensitive, safe, and human-aligned responses at inference time.

In the intensive care unit, the underlying causes of critical illness vary substantially across diagnoses, yet prediction models accounting for diagnostic heterogeneity have not been systematically studied. To address the gap, we evaluate transfer learning approaches for diagnosis-specific mortality prediction and apply both GLM- and XGBoost-based models to the eICU Collaborative Research Database. Our results demonstrate that transfer learning consistently outperforms models trained only on diagnosis-specific data and those using a well-known ICU severity-of-illness score, i.e., APACHE IVa, alone, while also achieving better calibration than models trained on the pooled data. Our findings also suggest that the Youden cutoff is a more appropriate decision threshold than the conventional 0.5 for binary outcomes, and that transfer learning maintains consistently high predictive performance across various cutoff criteria.

Understanding how protein mutations affect protein structure is essential for advancements in computational biology and bioinformatics. We introduce PRIMRose, a novel approach that predicts energy values for each residue given a mutated protein sequence. Unlike previous models that assess global energy shifts, our method analyzes the localized energetic impact of double amino acid insertions or deletions (InDels) at the individual residue level, enabling residue-specific insights into structural and functional disruption. We implement a Convolutional Neural Network architecture to predict the energy changes of each residue in a protein mutation. We train our model on datasets constructed from nine proteins, grouped into three categories: one set with exhaustive double InDel mutations, another with approximately 145k randomly sampled double InDel mutations, and a third with approximately 80k randomly sampled double InDel mutations. Our model achieves high predictive accuracy across a range of energy metrics as calculated by the Rosetta molecular modeling suite and reveals localized patterns that influence model performance, such as solvent accessibility and secondary structure context. This per-residue analysis offers new insights into the mutational tolerance of specific regions within proteins and provides higher interpretable and biologically meaningful predictions of InDels' effects.

Sampling algorithms play a pivotal role in probabilistic AI. However, verifying if a sampler program indeed samples from the claimed distribution is a notoriously hard problem. Provably correct testers like Barbarik, Teq, Flash, CubeProbe for testing of different kinds of samplers were proposed only in the last few years. All these testers focus on the worst-case efficiency, and do not support verification of samplers over infinite domains, a case occurring frequently in Astronomy, Finance, Network Security, etc. In this work, we design the first tester of samplers with instance-dependent efficiency, allowing us to test samplers over natural numbers. Our tests are developed via a novel distance estimation algorithm between an unknown and a known probability distribution using an interval conditioning framework. The core technical contribution is a new connection with probability mass estimation of a continuous distribution. The practical gains are also substantial: our experiments establish up to 1000x speedup over state-of-the-art testers.

Large language models (LLMs) are increasingly deployed on edge devices. To meet strict resource constraints, real-world deployment has pushed LLM quantization from 8-bit to 4-bit, 2-bit, and now 1.58-bit. Combined with lookup table (LUT)-based inference, CPUs run these ultra-low-bit LLMs even faster than NPUs, opening new opportunities for ubiquitous on-device intelligence. However, this paper identifies that LUT-based inference underutilizes memory bandwidth during parallel inference, which is required for prefilling, test-time scaling, and other multi-token scenarios. The root cause is the scalar LUT paradigm, which performs repetitive and non-contiguous memory accesses for each token. To solve the issue, we propose vector LUT, a new lookup paradigm that constructs a unified LUT across parallel tokens, and performs a single $1 \rightarrow N$ lookup per index. To realize it efficiently, we further introduce (1) Vector LUT-Centric Tensor Layout, and (2) Cache-Aware Streamed Lookup techniques. Evaluations on 5 edge devices across 3 LLMs show that Vec-LUT outperforms state-of-the-art baselines by up to $4.2\times$. Our implementation is integrated into llama.cpp. The code is available at https://github.com/Cipherxzc/vlut.cpp.

Preparticipation cardiovascular examination (PPCE) aims to prevent sudden cardiac death (SCD) by identifying athletes with structural or electrical cardiac abnormalities. Anthropometric measurements, such as waist circumference, limb lengths, and torso proportions to detect Marfan syndrome, can indicate elevated cardiovascular risk. Traditional manual methods are labor-intensive, operator-dependent, and challenging to scale. We present a fully automated deep-learning approach to estimate five key anthropometric measurements from 2D synthetic human body images. Using a dataset of 100,000 images derived from 3D body meshes, we trained and evaluated VGG19, ResNet50, and DenseNet121 with fully connected layers for regression. All models achieved sub-centimeter accuracy, with ResNet50 performing best, achieving a mean MAE of 0.668 cm across all measurements. Our results demonstrate that deep learning can deliver accurate anthropometric data at scale, offering a practical tool to complement athlete screening protocols. Future work will validate the models on real-world images to extend applicability.

Recent advances in LLM-based multi-agent systems have demonstrated remarkable capabilities in complex decision-making scenarios such as financial trading and software engineering. However, evaluating each individual agent's effectiveness and online optimization of underperforming agents remain open challenges. To address these issues, we present HiveMind, a self-adaptive framework designed to optimize LLM multi-agent collaboration through contribution analysis. At its core, HiveMind introduces Contribution-Guided Online Prompt Optimization (CG-OPO), which autonomously refines agent prompts based on their quantified contributions. We first propose the Shapley value as a grounded metric to quantify each agent's contribution, thereby identifying underperforming agents in a principled manner for automated prompt refinement. To overcome the computational complexity of the classical Shapley value, we present DAG-Shapley, a novel and efficient attribution algorithm that leverages the inherent Directed Acyclic Graph structure of the agent workflow to axiomatically prune non-viable coalitions. By hierarchically reusing intermediate outputs of agents in the DAG, our method further reduces redundant computations, and achieving substantial cost savings without compromising the theoretical guarantees of Shapley values. Evaluated in a multi-agent stock-trading scenario, HiveMind achieves superior performance compared to static baselines. Notably, DAG-Shapley reduces LLM calls by over 80\% while maintaining attribution accuracy comparable to full Shapley values, establishing a new standard for efficient credit assignment and enabling scalable, real-world optimization of multi-agent collaboration.

The availability and sophistication degree of such services are fair measures of progress for any city. In this context, Geographic information systems " GIS " offers solutions that support the decision - making processes regarding management, planning and distribution of services, ultimately improving the standard of living in cities (Aziz, 2007, p. 11). Investigating services planning standards is one of the most relevant issues concerning human progress regarding its proper definition and needs. Planning standards can be reconsidered by studying the variation in the distribution of geographical phenomena and the characteristi cs of geographic areas. More effort should be exerted in defining these standards parallel to the characteristics of each region. Such efforts will facilitate appropriate allocation s of services and accurate definitions of future developmental efforts. The problem of the study is that the planning standards are not suitable for the characteristics of the Egyptian cities, which include more population and intensive daily use of services. The solution to this problem is to create new planning standards that suit the rapidly changing nature of cities, and to generate these criteria current services and their intensity and the built - up areas are going to be used to reflect the characteristics of the city, taking this abroach is a new way to generate such criteria. This study attempts to derive planning standards for public services in the city of Qena that are compatible with the characteristics of the city, the geographical distribution of the population, the built - up area, and the services therein.

This work proposes PH-based metrics for benchmarking impedance control. A causality-consistent PH model is introduced for mass-spring-damper impedance in Cartesian space. Based on this model, a differentiable, force-torque sensing-independent, n-DoF passivity condition is derived, valid for time-varying references. An impedance fidelity metric is also defined from step-response power in free motion, capturing dynamic decoupling. The proposed metrics are validated in Gazebo simulations with a six-DoF manipulator and a quadruped leg. Results demonstrate the suitability of the PH framework for standardized impedance control benchmarking.

Recent advances in autoregressive (AR) generative models have produced increasingly powerful systems for media synthesis. Among them, next-scale prediction has emerged as a popular paradigm, where models generate images in a coarse-to-fine manner. However, scale-wise AR models suffer from exposure bias, which undermines generation quality. We identify two primary causes of this issue: (1) train-test mismatch, where the model must rely on its own imperfect predictions during inference, and (2) imbalance in scale-wise learning difficulty, where certain scales exhibit disproportionately higher optimization complexity. Through a comprehensive analysis of training dynamics, we propose Self-Autoregressive Refinement (SAR) to address these limitations. SAR introduces a Stagger-Scale Rollout (SSR) mechanism that performs lightweight autoregressive rollouts to expose the model to its own intermediate predictions, thereby aligning train-test patterns, and a complementary Contrastive Student-Forcing Loss (CSFL) that provides adequate supervision for self-generated contexts to ensure stable training. Experimental results show that applying SAR to pretrained AR models consistently improves generation quality with minimal computational overhead. For instance, SAR yields a 5.2% FID reduction on FlexVAR-d16 trained on ImageNet 256 within 10 epochs (5 hours on 32xA100 GPUs). Given its efficiency, scalability, and effectiveness, we expect SAR to serve as a reliable post-training method for visual autoregressive generation.