Diagnostic Medicine
Astronauts take first X-rays in space
More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Radiographs of the hand were acquired (A) preflight by a crewmember, (B) in-flight on day 1 after launch (L+1) by a crewmember, and (C) postflight by a non-crew operator using the same imaging protocol. Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy . For more than 40 years, ultrasound has remained the sole medical imaging method in space, but not by choice.
How healthy is your brain? We now know how to find out
How healthy is your brain? In our efforts to keep our brains healthy, how do we know what is working? It shouldn't have been difficult: 72 x 72. From the back seat, my daughter, newly confident in mental maths, wanted to check her answer. Whether it was because it was the end of the day, I was trying to park or something else, I stalled, cognitively speaking. Lately, though, I have had the sense that my brain isn't firing on all cylinders.
Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimation
Pal, Jimut B., Awate, Suyash P.
Deep neural networks (DNNs) frequently fail to generalize to out-of-distribution (OOD) medical images because of variations in scanners and acquisition protocols. Retraining DNN models to address these distribution shifts is often impractical due to the high cost of acquiring and annotating new medical datasets. To address this, we introduce VarDeepPCA, a novel lightweight variational DNN framework designed to restore/refine degraded segmentation maps by leveraging intrinsic geometric priors. Unlike existing approaches that require target-domain data or extensive pre-training, our VarDeepPCA explicitly learns a distribution of valid anatomical geometries using only small in-distribution (ID) datasets. Theoretically, our novel variational learning framework leverages a reinterpretation of the softmax mapping to implicitly perform exact distribution modeling, thereby enabling computationally efficient, sampling-free learning and inference. This also enables VarDeepPCA to provide uncertainty estimates associated with its restored segmentation maps. We empirically validate our framework across 4 distinct clinical applications, using 14 publicly available datasets, involving segmentation of the myocardium, neuroretinal rim, prostate, and fetal head. Comparisons against 15 existing methods demonstrate that VarDeepPCA consistently restores segmentation maps produced by the existing methods on OOD data to (i) significantly improve anatomical plausibility of geometries and clinical utility of the segmentations, and (ii) significantly reduce errors, without needing any more training data than that used by existing methods.
Pigeons are surprisingly good at detecting cancer
Scientists are using the birds' skills to train AI medical tools. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. They can even see ultraviolet light, which humans aren't able to. Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy .
RepoMaster: Autonomous Exploration and Understanding of GitHub Repositories for Complex Task Solving
The ultimate goal of code agents is to solve complex tasks autonomously. Although large language models (LLMs) have made substantial progress in code generation, real-world tasks typically demand full-fledged code repositories rather than simple scripts. Building such repositories from scratch remains a major challenge. Fortunately, GitHub hosts a vast, evolving collection of open-source repositories, which developers frequently reuse as modular components for complex tasks. Yet, existing frameworks like OpenHands and SWE-Agent still struggle to effectively leverage these valuable resources.
CPathAgent: An Agent-based Foundation Model for Interpretable High-Resolution Pathology Image Analysis Mimicking Pathologists ' Diagnostic Logic
Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply multimodal approaches to generate reports directly from images. However, these models cannot emulate the diagnostic approach of pathologists, who systematically examine slides at low magnification to obtain an overview before progressively zooming in on suspicious regions to formulate comprehensive diagnoses.
Aggregation Hides Out-of-Distribution Generalization Failures from Spurious Correlations
Benchmarks for out-of-distribution (OOD) generalization frequently show a strong positive correlation between in-distribution (ID) and OOD accuracy across models, termed "accuracy-on-the-line." This pattern is often taken to imply that spurious correlations--correlations that improve ID but reduce OOD performance--are rare in practice. We find that this positive correlation is often an artifact of aggregating heterogeneous OOD examples. Using a simple gradient-based method, OODSelect, we identify semantically coherent OOD subsets where accuracy on the line does not hold. Across widely used distribution shift benchmarks, the OODSelect uncovers subsets, sometimes up to over half of the standard OOD set, where higher ID accuracy predicts lower OOD accuracy. Our findings indicate that aggregate metrics can obscure important failure modes of OOD robustness. We release code and the identified subsets to facilitate further research.
AData-Driven Prism: Multi-View Source Separation with Diffusion Model Priors
A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual neurons from overlapping signals, and separating seismic events from an ambient background. Traditional analyses often rely on simplified source models that fail to accurately reproduce the data. Recent advances have shown that diffusion models can directly learn complex prior distributions from noisy, incomplete data. In this work, we show that diffusion models can solve the source separation problem without explicit assumptions about the source. Our method relies only on multiple views, or the property that different sets of observations contain different linear transformations of the unknown sources. We show that our method succeeds even when no source is individually observed and the observations are noisy, incomplete, and vary in resolution. The learned diffusion models enable us to sample from the source priors, evaluate the probability of candidate sources, and draw from the joint posterior of the source distribution given an observation. We demonstrate the effectiveness of our method on a range of synthetic problems as well as real-world galaxy observations.
Improving Deep Learning for Accelerated MRI With Data Filtering
Deep neural networks achieve state-of-the-art results for accelerated MRI reconstruction. Most research on deep learning based imaging focuses on improving neural network architectures trained and evaluated on fixed and homogeneous training and evaluation data. In this work, we investigate data curation strategies for improving MRI reconstruction. We assemble a large dataset of raw k-space data from 18 public sources consisting of 1.1M images and construct a diverse evaluation set comprising 48 test sets, capturing variations in anatomy, contrast, number of coils, and other key factors. We propose and study different data filtering strategies to enhance performance of current state-of-the-art neural networks for accelerated MRI reconstruction. Our experiments show that filtering the training data leads to consistent, albeit modest, performance gains. These performance gains are robust across different training set sizes and accelerations, and we find that filtering is particularly beneficial when the proportion of in-distribution data in the unfiltered training set is low.