Diagnostic Medicine
Pigeons are surprisingly good at detecting cancer
Scientists are using the birds' skills to train AI medical tools. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. They can even see ultraviolet light, which humans aren't able to. Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy .
RepoMaster: Autonomous Exploration and Understanding of GitHub Repositories for Complex Task Solving
The ultimate goal of code agents is to solve complex tasks autonomously. Although large language models (LLMs) have made substantial progress in code generation, real-world tasks typically demand full-fledged code repositories rather than simple scripts. Building such repositories from scratch remains a major challenge. Fortunately, GitHub hosts a vast, evolving collection of open-source repositories, which developers frequently reuse as modular components for complex tasks. Yet, existing frameworks like OpenHands and SWE-Agent still struggle to effectively leverage these valuable resources.
CPathAgent: An Agent-based Foundation Model for Interpretable High-Resolution Pathology Image Analysis Mimicking Pathologists ' Diagnostic Logic
Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply multimodal approaches to generate reports directly from images. However, these models cannot emulate the diagnostic approach of pathologists, who systematically examine slides at low magnification to obtain an overview before progressively zooming in on suspicious regions to formulate comprehensive diagnoses.
Aggregation Hides Out-of-Distribution Generalization Failures from Spurious Correlations
Benchmarks for out-of-distribution (OOD) generalization frequently show a strong positive correlation between in-distribution (ID) and OOD accuracy across models, termed "accuracy-on-the-line." This pattern is often taken to imply that spurious correlations--correlations that improve ID but reduce OOD performance--are rare in practice. We find that this positive correlation is often an artifact of aggregating heterogeneous OOD examples. Using a simple gradient-based method, OODSelect, we identify semantically coherent OOD subsets where accuracy on the line does not hold. Across widely used distribution shift benchmarks, the OODSelect uncovers subsets, sometimes up to over half of the standard OOD set, where higher ID accuracy predicts lower OOD accuracy. Our findings indicate that aggregate metrics can obscure important failure modes of OOD robustness. We release code and the identified subsets to facilitate further research.
AData-Driven Prism: Multi-View Source Separation with Diffusion Model Priors
A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual neurons from overlapping signals, and separating seismic events from an ambient background. Traditional analyses often rely on simplified source models that fail to accurately reproduce the data. Recent advances have shown that diffusion models can directly learn complex prior distributions from noisy, incomplete data. In this work, we show that diffusion models can solve the source separation problem without explicit assumptions about the source. Our method relies only on multiple views, or the property that different sets of observations contain different linear transformations of the unknown sources. We show that our method succeeds even when no source is individually observed and the observations are noisy, incomplete, and vary in resolution. The learned diffusion models enable us to sample from the source priors, evaluate the probability of candidate sources, and draw from the joint posterior of the source distribution given an observation. We demonstrate the effectiveness of our method on a range of synthetic problems as well as real-world galaxy observations.
Improving Deep Learning for Accelerated MRI With Data Filtering
Deep neural networks achieve state-of-the-art results for accelerated MRI reconstruction. Most research on deep learning based imaging focuses on improving neural network architectures trained and evaluated on fixed and homogeneous training and evaluation data. In this work, we investigate data curation strategies for improving MRI reconstruction. We assemble a large dataset of raw k-space data from 18 public sources consisting of 1.1M images and construct a diverse evaluation set comprising 48 test sets, capturing variations in anatomy, contrast, number of coils, and other key factors. We propose and study different data filtering strategies to enhance performance of current state-of-the-art neural networks for accelerated MRI reconstruction. Our experiments show that filtering the training data leads to consistent, albeit modest, performance gains. These performance gains are robust across different training set sizes and accelerations, and we find that filtering is particularly beneficial when the proportion of in-distribution data in the unfiltered training set is low.
Segment Anything Model Meets Semi-supervised Medical Image Segmentation: ANovel Perspective
The scarcity of annotated medical imaging data has driven significant progress in semi-supervised learning to alleviate reliance on expensive expert labeling. While foundational vision models such as the Segment Anything Model (SAM) exhibit robust generalization in generic segmentation tasks, their direct application to medical images often results in suboptimal performance. To address this challenge, in this work, we propose a novel fully SAM-based semi-supervised medical image segmentation framework and develop the corresponding knowledge distillationbased learning strategy. Specifically, we first employ an efficient SAM variant as the backbone network of the semi-supervised framework and update the default prompt embedding of SAM to unleash its full potential. Then, we utilize an original SAM, which is rich in prior knowledge, as the teacher to optimize our efficient student SAM backbone through hierarchical knowledge distillation and a dynamic loss weighting strategy. Extensive experiments on various medical datasets demonstrate that our method outperforms state-of-the-art semi-supervised segmentation approaches. Especially, our model requires less than 10% of the parameter size of the original SAM, enabling substantially lower deployment and storage overhead in real-world clinical settings.
PhysioWave: AMulti-Scale Wavelet-Transformer for Physiological Signal Representation
Physiological signals are often corrupted by motion artifacts, baseline drift, and other low-SNR disturbances, which pose significant challenges for analysis. Additionally, these signals exhibit strong non-stationarity, with sharp peaks and abrupt changes that evolve continuously, making them difficult to represent using traditional time-domain or filtering methods. To address these issues, a novel waveletbased approach for physiological signal analysis is presented, aiming to capture multi-scale time-frequency features in various physiological signals. Leveraging this technique, two large-scale pretrained models specific to EMG and ECG are introduced for the first time, achieving superior performance and setting new baselines in downstream tasks. Additionally, a unified multi-modal framework is constructed by integrating pretrained EEG model, where each modality is guided through its dedicated branch and fused via learnable weighted fusion. This design effectively addresses challenges such as low signal-to-noise ratio, high inter-subject variability, and device mismatch, outperforming existing methods on multi-modal tasks. The proposed wavelet-based architecture lays a solid foundation for analysis of diverse physiological signals, while the multi-modal design points to nextgeneration physiological signal processing with potential impact on wearable health monitoring, clinical diagnostics, and broader biomedical applications.
UniMRSeg: Unified Modality-Relax Segmentation via Hierarchical Self-Supervised Compensation
Multi-modal image segmentation faces real-world deployment challenges from incomplete/corrupted modalities degrading performance. While existing methods address training-inference modality gaps via specialized per-combination models, they introduce high deployment costs by requiring exhaustive model subsets and model-modality matching. In this work, we propose a unified modality-relax segmentation network (UniMRSeg) through hierarchical self-supervised compensation (HSSC).