This paper presents VITA (Virtual Teaching Assistants), an adaptive distributed learning (ADL) platform that embeds a large language model (LLM)-powered chatbot (BotCaptain) to provide dialogic support, interoperable analytics, and integrity-aware assessment for workforce preparation in data science. The platform couples context-aware conversational tutoring with formative-assessment patterns designed to promote reflective reasoning. The paper describes an end-to-end data pipeline that transforms chat logs into Experience API (xAPI) statements, instructor dashboards that surface outliers for just-in-time intervention, and an adaptive pathway engine that routes learners among progression, reinforcement, and remediation content. The paper also benchmarks VITA conceptually against emerging tutoring architectures, including retrieval-augmented generation (RAG)--based assistants and Learning Tools Interoperability (LTI)--integrated hubs, highlighting trade-offs among content grounding, interoperability, and deployment complexity. Contributions include a reusable architecture for interoperable conversational analytics, a catalog of patterns for integrity-preserving formative assessment, and a practical blueprint for integrating adaptive pathways into data-science courses. The paper concludes with implementation lessons and a roadmap (RAG integration, hallucination mitigation, and LTI~1.3 / OpenID Connect) to guide multi-course evaluations and broader adoption. In light of growing demand and scalability constraints in traditional instruction, the approach illustrates how conversational AI can support engagement, timely feedback, and personalized learning at scale. Future work will refine the platform's adaptive intelligence and examine applicability across varied educational settings.

Attention-based models have become the leading approach in modeling medical language for Natural Language Processing (NLP) in clinical notes. These models outperform traditional techniques by effectively capturing contextual representations of language. In this research a comparative analysis is done amongst pre-trained attention based models namely Bert Base, BioBert, two variations of Bio+Clinical Bert, RoBerta, and Clinical Longformer on task related to Electronic Health Record (EHR) information extraction. The tasks from Track 1 of Harvard Medical School's 2022 National Clinical NLP Challenges (n2c2) are considered for this comparison, with the Contextualized Medication Event Dataset (CMED) given for these task. CMED is a dataset of unstructured EHRs and annotated notes that contain task relevant information about the EHRs. The goal of the challenge is to develop effective solutions for extracting contextual information related to patient medication events from EHRs using data driven methods. Each pre-trained model is fine-tuned and applied on CMED to perform medication extraction, medical event detection, and multi-dimensional medication event context classification. Processing methods are also detailed for breaking down EHRs for compatibility with the applied models. Performance analysis has been carried out using a script based on constructing medical terms from the evaluation portion of CMED with metrics including recall, precision, and F1-Score. The results demonstrate that models pre-trained on clinical data are more effective in detecting medication and medication events, but Bert Base, pre-trained on general domain data showed to be the most effective for classifying the context of events related to medications.

The size, diversity, and quality of pretraining datasets critically determine the generalization ability of foundation models. Despite their growing importance in chemoinformatics, the effectiveness of molecular representation learning has been hindered by limitations in existing small molecule datasets. To address this gap, we present MolPILE, large-scale, diverse, and rigorously curated collection of 222 million compounds, constructed from 6 large-scale databases using an automated curation pipeline. We present a comprehensive analysis of current pre-training datasets, highlighting considerable shortcomings for training ML models, and demonstrate how retraining existing models on MolPILE yields improvements in generalization performance. This work provides a standardized resource for model training, addressing the pressing need for an ImageNet-like dataset in molecular chemistry. Modern chemoinformatics relies extensively on machine learning (ML) methods, particularly for virtual ...

Analog quantum simulators with global control fields have emerged as powerful platforms for exploring complex quantum phenomena. Recent breakthroughs, such as the coherent control of thousands of atoms, highlight the growing potential for quantum applications at scale. Despite these advances, a fundamental theoretical question remains unresolved: to what extent can such systems realize universal quantum dynamics under global control? Here we establish a necessary and sufficient condition for universal quantum computation using only global pulse control, proving that a broad class of analog quantum simulators is, in fact, universal. We further extend this framework to fermionic and bosonic systems, including modern platforms such as ultracold atoms in optical superlattices. Crucially, to connect the theoretical possibility with experimental reality, we introduce a new control technique into the experiment - direct quantum optimal control. This method enables the synthesis of complex effective Hamiltonians and allows us to incorporate realistic hardware constraints. To show its practical power, we experimentally engineer three-body interactions outside the blockade regime and demonstrate topological dynamics on a Rydberg atom array. Using the new control framework, we overcome key experimental challenges, including hardware limitations and atom position fluctuations in the non-blockade regime, by identifying smooth, short-duration pulses that achieve high-fidelity dynamics. Experimental measurements reveal dynamical signatures of symmetry-protected-topological edge modes, confirming both the expressivity and feasibility of our approach. Our work opens a new avenue for quantum simulation beyond native hardware Hamiltonians, enabling the engineering of effective multi-body interactions and advancing the frontier of quantum information processing with globally-controlled analog platforms.

Abstract--Generative models are increasingly adopted in high-stakes domains, yet current deployments offer no mechanisms to verify whether a given output truly originates from the certified model. We address this gap by extending model fingerprinting techniques beyond the traditional collaborative setting to one where the model provider itself may act adversarially, replacing the certified model with a cheaper or lower-quality substitute. T o our knowledge, this is the first work to study fingerprinting for provenance attribution under such a threat model. Our approach introduces a trusted verifier that, during a certification phase, extracts hidden fingerprints from the authentic model's output space and trains a detector to recognize them. During verification, this detector can determine whether new outputs are consistent with the certified model, without requiring specialized hardware or model modifications. In extensive experiments, our methods achieve near-zero FPR@95%TPR on both GANs and diffusion models, and remain effective even against subtle architectural or training changes. Furthermore, the approach is robust to adaptive adversaries that actively manipulate outputs in an attempt to evade detection. Recent advances in generative AI have led to the widespread deployment of generative models across various domains, with providers of generative AI services increasingly monetizing their models by offering subscription-based access. However, this rapid adoption has raised serious concerns about the risks posed by these models, particularly in safety-critical domains, such as healthcare and defense, where erroneous model outputs can have disastrous consequences [1]. In response, policymakers are introducing legal frameworks to regulate the use of AI and, in particular, the deployment of generative models. For instance, the European Union's AI Act mandates independent, periodic audits for "high-risk" AI systems deployed in domains such as healthcare, education, employment, and critical infrastructure [2]. This requirement to pass or be certified by an audit raises a critical question: How can users verify that a given output indeed originated from the audited model?

Money laundering enables organized crime by moving illicit funds into the legitimate economy. Although trillions of dollars are laundered each year, detection rates remain low because launderers evade oversight, confirmed cases are rare, and institutions see only fragments of the global transaction network. Since access to real transaction data is tightly restricted, synthetic datasets are essential for developing and evaluating detection methods. However, existing datasets fall short: they often neglect partial observability, temporal dynamics, strategic behavior, uncertain labels, class imbalance, and network-level dependencies. We introduce AMLGentex, an open-source suite for generating realistic, configurable transaction data and benchmarking detection methods. AMLGentex enables systematic evaluation of anti-money laundering systems under conditions that mirror real-world challenges. By releasing multiple country-specific datasets and practical parameter guidance, we aim to empower researchers and practitioners and provide a common foundation for collaboration and progress in combating money laundering.

Competing risks are crucial considerations in survival modelling, particularly in healthcare domains where patients may experience multiple distinct event types. We propose CRISP-NAM (Competing Risks Interpretable Survival Prediction with Neural Additive Models), an interpretable neural additive model for competing risks survival analysis which extends the neural additive architecture to model cause-specific hazards while preserving feature-level interpretability. Each feature contributes independently to risk estimation through dedicated neural networks, allowing for visualization of complex non-linear relationships between covariates and each competing risk. We demonstrate competitive performance on multiple datasets compared to existing approaches.

Accurate crop-type classification from satellite time series is essential for agricultural monitoring. While various machine learning algorithms have been developed to enhance performance on data-scarce tasks, their evaluation often lacks real-world scenarios. Consequently, their efficacy in challenging practical applications has not yet been profoundly assessed. To facilitate future research in this domain, we present the first comprehensive benchmark for evaluating supervised and SSL methods for crop-type classification under real-world conditions. This benchmark study relies on the EuroCropsML time-series dataset, which combines farmer-reported crop data with Sentinel-2 satellite observations from Estonia, Latvia, and Portugal. Our findings indicate that MAML-based meta-learning algorithms achieve slightly higher accuracy compared to supervised transfer learning and SSL methods. However, compared to simpler transfer learning, the improvement of meta-learning comes at the cost of increased computational demands and training time. Moreover, supervised methods benefit most when pre-trained and fine-tuned on geographically close regions. In addition, while SSL generally lags behind meta-learning, it demonstrates advantages over training from scratch, particularly in capturing fine-grained features essential for real-world crop-type classification, and also surpasses standard transfer learning. This highlights its practical value when labeled pre-training crop data is scarce. Our insights underscore the trade-offs between accuracy and computational demand in selecting supervised machine learning methods for real-world crop-type classification tasks and highlight the difficulties of knowledge transfer across diverse geographic regions. Furthermore, they demonstrate the practical value of SSL approaches when labeled pre-training crop data is scarce.

Large artificial intelligence (AI) models have garnered significant attention for their remarkable, often "superhuman", performance on standardized benchmarks. However, when these models are deployed in high-stakes verticals such as healthcare, education, and law, they often reveal notable limitations. For instance, they exhibit brittleness to minor variations in input data, present contextually uninformed decisions in critical settings, and undermine user trust by confidently producing or reproducing inaccuracies. These challenges in applying large models necessitate cross-disciplinary innovations to align the models' capabilities with the needs of real-world applications. We introduce a framework that addresses this gap through a layer-wise abstraction of innovations aimed at meeting users' requirements with large models. Through multiple case studies, we illustrate how researchers and practitioners across various fields can operationalize this framework. Beyond modularizing the pipeline of transforming large models into useful "vertical systems", we also highlight the dynamism that exists within different layers of the framework. Finally, we discuss how our framework can guide researchers and practitioners to (i) optimally situate their innovations (e.g., when vertical-specific insights can empower broadly impactful vertical-agnostic innovations), (ii) uncover overlooked opportunities (e.g., spotting recurring problems across verticals to develop practically useful foundation models instead of chasing benchmarks), and (iii) facilitate cross-disciplinary communication of critical challenges (e.g., enabling a shared vocabulary for AI developers, domain experts, and human-computer interaction scholars).

The increasing reliance on machine learning systems has made their security a critical concern. Evasion attacks enable adversaries to manipulate the decision-making processes of AI systems, potentially causing security breaches or misclassification of targets. Vision Transformers (ViTs) have gained significant traction in modern machine learning due to increased 1) performance compared to Convolutional Neural Networks (CNNs) and 2) robustness against adversarial perturbations. However, ViTs remain vulnerable to evasion attacks, particularly to adversarial patches, unique patterns designed to manipulate AI classification systems. These vulnerabilities are investigated by designing realistic adversarial patches to cause misclassification in person vs. non-person classification tasks using the Creases Transformation (CT) technique, which adds subtle geometric distortions similar to those occurring naturally when wearing clothing. This study investigates the transferability of adversarial attack techniques used in CNNs when applied to ViT classification models. Experimental evaluation across four fine-tuned ViT models on a binary person classification task reveals significant vulnerability variations: attack success rates ranged from 40.04% (google/vit-base-patch16-224-in21k) to 99.97% (facebook/dino-vitb16), with google/vit-base-patch16-224 achieving 66.40% and facebook/dinov3-vitb16 reaching 65.17%. These results confirm the cross-architectural transferability of adversarial patches from CNNs to ViTs, with pre-training dataset scale and methodology strongly influencing model resilience to adversarial attacks.