Traditional Chinese Medicine diagnosis and treatment principles, established through centuries of trial-and-error clinical practice, directly maps patient-specific symptom patterns to personalised herbal therapies. These empirical holistic mapping principles offer valuable strategies to address remaining challenges of reductionism methodologies in modern biomedicine. However, the lack of a quantitative framework and molecular-level evidence has limited their interpretability and reliability. Here, we present an AI framework trained on ancient and classical TCM formula records to quantify the symptom pattern-herbal therapy mappings. Interestingly, we find that empirical TCM diagnosis and treatment are consistent with the encoding-decoding processes in the AI model. This enables us to construct an interpretable TCM embedding space (TCM-ES) using the model's quantitative representation of TCM principles. Validated through broad and extensive TCM patient data, the TCM-ES offers universal quantification of the TCM practice and therapeutic efficacy. We further map biomedical entities into the TCM-ES through correspondence alignment. We find that the principal directions of the TCM-ES are significantly associated with key biological functions (such as metabolism, immune, and homeostasis), and that the disease and herb embedding proximity aligns with their genetic relationships in the human protein interactome, which demonstrate the biological significance of TCM principles. Moreover, the TCM-ES uncovers latent disease relationships, and provides alternative metric to assess clinical efficacy for modern disease-drug pairs. Finally, we construct a comprehensive and integrative TCM knowledge graph, which predicts potential associations between diseases and targets, drugs, herbal compounds, and herbal therapies, providing TCM-informed opportunities for disease analysis and drug development.

In multiple unmanned ground vehicle confrontations, autonomously evolving multi-agent tactical decisions from situational awareness remain a significant challenge. Traditional handcraft rule-based methods become vulnerable in the complicated and transient battlefield environment, and current reinforcement learning methods mainly focus on action manipulation instead of strategic decisions due to lack of interpretability. Here, we propose a vision-language model-based commander to address the issue of intelligent perception-to-decision reasoning in autonomous confrontations. Our method integrates a vision language model for scene understanding and a lightweight large language model for strategic reasoning, achieving unified perception and decision within a shared semantic space, with strong adaptability and interpretability. Unlike rule-based search and reinforcement learning methods, the combination of the two modules establishes a full-chain process, reflecting the cognitive process of human commanders. Simulation and ablation experiments validate that the proposed approach achieves a win rate of over 80% compared with baseline models.

This study explores the potential for predicting turbulent kinetic energy (TKE) from more readily acquired temperature data using temperature profiles and turbulence data collected concurrently at 10 Hz during a small experimental prescribed burn in the New Jersey Pine Barrens. Machine learning models, including Deep Neural Networks, Random Forest Regressor, Gradient Boosting, and Gaussian Process Regressor, were employed to assess the potential to predict TKE from temperature perturbations and explore temporal and spatial dynamics of correlations. Data visualization and correlation analyses revealed patterns and relationships between thermocouple temperatures and TKE, providing insight into the underlying dynamics. More accurate predictions of TKE were achieved by employing various machine learning models despite a weak correlation between the predictors and the target variable. The results demonstrate significant success, particularly from regression models, in accurately predicting the TKE. The findings of this study demonstrate a novel numerical approach to identifying new relationships between temperature and airflow processes in and around the fire environment. These relationships can help refine our understanding of combustion environment processes and the coupling and decoupling of fire environment processes necessary for improving fire operations strategy and fire and smoke model predictions. The findings of this study additionally highlight the valuable role of machine learning techniques in analyzing the complex large datasets of the fire environments, showcasing their potential to advance fire research and management practices. Introduction Wildland fire is a natural and essential ecological process.

Due to climate-induced changes, many habitats are experiencing range shifts away from their traditional geographic locations (Piguet, 2011). We propose a solution to accurately model whether bird species are present in a specific habitat through the combination of Convolutional Neural Networks (CNNs) (O'Shea, 2015) and tabular data. Our approach makes use of satellite imagery and environmental features (e.g., temperature, precipitation, elevation) to predict bird presence across various climates. The CNN model captures spatial characteristics of landscapes such as forestation, water bodies, and urbanization, whereas the tabular method uses ecological and geographic data. Both systems predict the distribution of birds with an average accuracy of 85%, offering a scalable but reliable method to understand bird migration.

AI models need to be unlearned to fulfill the requirements of legal acts such as the AI Act or GDPR, and also because of the need to remove toxic content, debiasing, the impact of malicious instances, or changes in the data distribution structure in which a model works. Unfortunately, removing knowledge may cause undesirable side effects, such as a deterioration in model performance. In this paper, we investigate the problem of adversarial unlearning, where a malicious party intentionally sends unlearn requests to deteriorate the model's performance maximally. We show that this phenomenon and the adversary's capabilities depend on many factors, primarily on the backbone model itself and strategy/limitations in selecting data to be unlearned. The main result of this work is a new method of protecting model performance from these side effects, both in the case of unlearned behavior resulting from spontaneous processes and adversary actions.

Second, no established benchmarks evaluate performance under hardware constraints equivalent to flight computers (less than 4GB RAM, CPU-only inference) and inference time constraints (inference time less than 0. 95 second). Third, conventional metrics such as the Dice coefficient fail to capture boundary localization precision critical for proximity operations. These gaps hinder the development of algorithms that can be deployed on resource-constrained orbital platforms. To address these challenges, we introduce a dual-methodology dataset synthesis approach. Building on the Pose-Bowl and Spacecrafts datasets, we created our dataset, Spacecraft With Masks (SwiM), through two complementary strategies: (1) superimposing existing spacecraft images on augmented open-source backgrounds with photometric/geometric distortions to mimic real-world noise and distortions in image acquisition in space, and (2) generating synthetic samples via NASA's TT ALOS (Toolset for Training and Labeling in an Optical Simulator) pipeline, which integrates astrophysical backgrounds generated using stable diffusion with procedu-rally rendered 3D spacecraft models. This hybrid methodology achieves unprecedented diversity in spacecraft poses, lighting conditions, and environmental contexts while maintaining physical precision and simulating camera distortions and noise. To the best of our knowledge, our SWiM dataset, consisting of nearly 64k images with annotations, is the largest and most comprehensive spacecraft segmentation dataset to date.

Individuals are increasingly relying on large language model (LLM)-enabled conversational agents for emotional support. While prior research has examined privacy and security issues in chatbots specifically designed for mental health purposes, these chatbots are overwhelmingly "rule-based" offerings that do not leverage generative AI. Little empirical research currently measures users' privacy and security concerns, attitudes, and expectations when using general-purpose LLM-enabled chatbots to manage and improve mental health. Through 21 semi-structured interviews with U.S. participants, we identified critical misconceptions and a general lack of risk awareness. Participants conflated the human-like empathy exhibited by LLMs with human-like accountability and mistakenly believed that their interactions with these chatbots were safeguarded by the same regulations (e.g., HIPAA) as disclosures with a licensed therapist. We introduce the concept of "intangible vulnerability," where emotional or psychological disclosures are undervalued compared to more tangible forms of information (e.g., financial or location-based data). To address this, we propose recommendations to safeguard user mental health disclosures with general-purpose LLM-enabled chatbots more effectively.

Passive deformation due to compliance is a commonly used benefit of soft robots, providing opportunities to achieve robust actuation with few active degrees of freedom. Soft growing robots in particular have shown promise in navigation of unstructured environments due to their passive deformation. If their collisions and subsequent deformations can be better understood, soft robots could be used to understand the structure of the environment from direct tactile measurements. In this work, we propose the use of soft growing robots as mapping and exploration tools. We do this by first characterizing collision behavior during discrete turns, then leveraging this model to develop a geometry-based simulator that models robot trajectories in 2D environments. Finally, we demonstrate the model and simulator validity by mapping unknown environments using Monte Carlo sampling to estimate the optimal next deployment given current knowledge. Over both uniform and non-uniform environments, this selection method rapidly approaches ideal actions, showing the potential for soft growing robots in unstructured environment exploration and mapping.

Protecting cyberspace requires not only advanced tools but also a shift in how we reason about threats, trust, and autonomy. Traditional cybersecurity methods rely on manual responses and brittle heuristics. To build proactive and intelligent defense systems, we need integrated theoretical frameworks and software tools. Game theory provides a rigorous foundation for modeling adversarial behavior, designing strategic defenses, and enabling trust in autonomous systems. Meanwhile, software tools process cyber data, visualize attack surfaces, verify compliance, and suggest mitigations. Yet a disconnect remains between theory and practical implementation. The rise of Large Language Models (LLMs) and agentic AI offers a new path to bridge this gap. LLM-powered agents can operationalize abstract strategies into real-world decisions. Conversely, game theory can inform the reasoning and coordination of these agents across complex workflows. LLMs also challenge classical game-theoretic assumptions, such as perfect rationality or static payoffs, prompting new models aligned with cognitive and computational realities. This co-evolution promises richer theoretical foundations and novel solution concepts. Agentic AI also reshapes software design: systems must now be modular, adaptive, and trust-aware from the outset. This chapter explores the intersection of game theory, agentic AI, and cybersecurity. We review key game-theoretic frameworks (e.g., static, dynamic, Bayesian, and signaling games) and solution concepts. We then examine how LLM agents can enhance cyber defense and introduce LLM-driven games that embed reasoning into AI agents. Finally, we explore multi-agent workflows and coordination games, outlining how this convergence fosters secure, intelligent, and adaptive cyber systems.

Manila, Philippines – When former Philippines President Rodrigo Duterte was arrested by the International Criminal Court (ICC) in March, Sheerah Escuerdo spoke to a local television station, welcoming the politician's detention on charges of murder linked to his war on drugs. Escuerdo, who lost her 18-year-old brother, Ephraim, to Duterte's war, clutched a portrait of her sibling during the interview with News 5 Everywhere as she demanded justice for his killing. Days later, she was shocked to find an AI-generated video of her slain brother circulating on Facebook, in which he said he was alive and accused his sister of lying. Are they paying you to do this?" the computer-generated image of Ephraim said. The video, posted online by a pro-Duterte influencer with 11,000 followers, immediately drew thousands of views on Facebook. One of the comments read, "Fake drug war victims". It was Escudero and her brother's image from her News 5 Everywhere interview that the influencer had used to ...