Deep learning (DL) has shown great potential in medical image enhancement problems, such as super-resolution or image synthesis. However, to date, little consideration has been given to uncertainty quantification over the output image. Here we introduce methods to characterise different components of uncertainty in such problems and demonstrate the ideas using diffusion MRI super-resolution. Specifically, we propose to account for $intrinsic$ uncertainty through a heteroscedastic noise model and for $parameter$ uncertainty through approximate Bayesian inference, and integrate the two to quantify $predictive$ uncertainty over the output image. Moreover, we introduce a method to propagate the predictive uncertainty on a multi-channelled image to derived scalar parameters, and separately quantify the effects of intrinsic and parameter uncertainty therein. The methods are evaluated for super-resolution of two different signal representations of diffusion MR images---DTIs and Mean Apparent Propagator MRI---and their derived quantities such as MD and FA, on multiple datasets of both healthy and pathological human brains. Results highlight three key benefits of uncertainty modelling for improving the safety of DL-based image enhancement systems. Firstly, incorporating uncertainty improves the predictive performance even when test data departs from training data. Secondly, the predictive uncertainty highly correlates with errors, and is therefore capable of detecting predictive "failures". Results demonstrate that such an uncertainty measure enables subject-specific and voxel-wise risk assessment of the output images. Thirdly, we show that the method for decomposing predictive uncertainty into its independent sources provides high-level "explanations" for the performance by quantifying how much uncertainty arises from the inherent difficulty of the task or the limited training examples.

This paper studies learning the representations of whole graphs in both unsupervised and semi-supervised scenarios. Graph-level representations are critical in a variety of real-world applications such as predicting the properties of molecules and community analysis in social networks. Traditional graph kernel based methods are simple, yet effective for obtaining fixed-length representations for graphs but they suffer from poor generalization due to hand-crafted designs. There are also some recent methods based on language models (e.g. graph2vec) but they tend to only consider certain substructures (e.g. subtrees) as graph representatives. Inspired by recent progress of unsupervised representation learning, in this paper we proposed a novel method called InfoGraph for learning graph-level representations. We maximize the mutual information between the graph-level representation and the representations of substructures of different scales (e.g., nodes, edges, triangles). By doing so, the graph-level representations encode aspects of the data that are shared across different scales of substructures. Furthermore, we further propose InfoGraph*, an extension of InfoGraph for semi-supervised scenarios. InfoGraph* maximizes the mutual information between unsupervised graph representations learned by InfoGraph and the representations learned by existing supervised methods. As a result, the supervised encoder learns from unlabeled data while preserving the latent semantic space favored by the current supervised task. Experimental results on the tasks of graph classification and molecular property prediction show that InfoGraph is superior to state-of-the-art baselines and InfoGraph* can achieve performance competitive with state-of-the-art semi-supervised models.

Imagine where you could take your business if you knew the next product a customer is going to buy or if a transaction is fraudulent. This is what Machine Learning (ML) promises. Machine Learning allows businesses to challenge the status quo, creating tremendous disruption. Already, many companies are using Machine Learning to create new business opportunities. Are you determined to bring Machine Learning into your organization?

Artificial intelligence is here to stay. It's having a profound impact on education, and that impact will almost certainly expand over time. Is this a positive direction for students and teachers, or is it a slippery slope away from engaged, thoughtful learning? Different stakeholders have very different points of view on this subject, and for good reason. Like any tool, AI has its limits--but it can also provide an impressive array of tools for teaching and learning.

While HR is not known for pioneering nascent technologies, Artificial Intelligence (AI) represents a terrific opportunity. The consumerization of HR technologies has brought AI to the forefront of innovation in HR. From recruitment to employee experience, and talent management, AI has the potential to transform HR. The future of HR is both digital and human as HR leaders focus on optimizing the combination of human and automated work. This is driving a new priority for HR: one which requires leaders and teams to develop fluency in artificial intelligence while they reimagine HR to be more personal and engaging especially for the candidates; strategic and forward-looking to the business.

We present here the Temporal Clustering Algorithm (TCA), an incremental learning algorithm applicable to problems of anticipatory computing in the context of the Internet of Things. This algorithm was tested in a specific prediction scenario of consumption of an electric water dispenser typically used in tropical countries, in which the ambient temperature is around 30-degree Celsius. In this context, the user typically wants to drinking iced water therefore uses the cooler function of the dispenser. Real and synthetic water consumption data was used to test a forecasting capacity on how much energy can be saved by predicting the pattern of use of the equipment. In addition to using a small constant amount of memory, which allows the algorithm to be implemented at the lowest cost, while using microcontrollers with a small amount of memory (less than 1Kbyte) available on the market. The algorithm can also be configured according to user preference, prioritizing comfort, keeping the water at the desired temperature longer, or prioritizing energy savings. The main result is that the TCA achieved energy savings of up to 40% compared to the conventional mode of operation of the dispenser with an average success rate higher than 90% in its times of use.

Dialogue systems are increasingly using knowledge bases (KBs) storing real-world facts to help generate quality responses. However, as the KBs are inherently incomplete and remain fixed during conversation, it limits dialogue systems' ability to answer questions and to handle questions involving entities or relations that are not in the KB. In this paper, we make an attempt to propose an engine for Continuous and Interactive Learning of Knowledge (CILK) for dialogue systems to give them the ability to continuously and interactively learn and infer new knowledge during conversations. With more knowledge accumulated over time, they will be able to learn better and answer more questions. Our empirical evaluation shows that CILK is promising.

Outside of their ability to understand a company's fundamentals, one of the skills Raj Lala appreciates most about his portfolio managers is their ability to interpret body language. Sitting across from management teams before making a decision to either invest or divest from their companies, Lala, the CEO of Evolve ETFs, said his portfolio managers can learn a lot from simply reading the room. Maybe they spot a nervous twitch after a question on guidance or a CEO unable to make eye contact when responding to a question about declining revenues. That very human capability was at the forefront of Lala's mind when he was recently pitched on two types of artificial intelligence that he could incorporate into his portfolio management processes. And it's one of the reasons he said no. "I can't see AI getting to that point where it replaces human interaction and, quite honestly, I would say god bless our world if that's the case," Lala said.

We propose a framework for interactive and explainable machine learning that enables users to (1) understand machine learning models; (2) diagnose model limitations using different explainable AI methods; as well as (3) refine and optimize the models. Our framework combines an iterative XAI pipeline with eight global monitoring and steering mechanisms, including quality monitoring, provenance tracking, model comparison, and trust building. To operationalize the framework, we present explAIner, a visual analytics system for interactive and explainable machine learning that instantiates all phases of the suggested pipeline within the commonly used TensorBoard environment. We performed a user-study with nine participants across different expertise levels to examine their perception of our workflow and to collect suggestions to fill the gap between our system and framework. The evaluation confirms that our tightly integrated system leads to an informed machine learning process while disclosing opportunities for further extensions.

Current AI approaches have frequently been used to help personalize many aspects of medical experiences and tailor them to a specific individuals' needs. However, while such systems consider medically-relevant information, they ignore socially-relevant information about how this diagnosis should be communicated and discussed with the patient. The lack of this capability may lead to mis-communication, resulting in serious implications, such as patients opting out of the best treatment. Consider a case in which the same treatment is proposed to two different individuals. The manner in which this treatment is mediated to each should be different, depending on the individual patient's history, knowledge, and mental state. While it is clear that this communication should be conveyed via a human medical expert and not a software-based system, humans are not always capable of considering all of the relevant aspects and traversing all available information. We pose the challenge of creating Intelligent Agents (IAs) to assist medical service providers (MSPs) and consumers in establishing a more personalized human-to-human dialogue. Personalizing conversations will enable patients and MSPs to reach a solution that is best for their particular situation, such that a relation of trust can be built and commitment to the outcome of the interaction is assured. We propose a four-part conceptual framework for personalized social interactions, expand on which techniques are available within current AI research and discuss what has yet to be achieved.