Surgical simulations offer a significant advantage by eliminating the need for patient involvement in skills practice, providing trainees with essential technical lessons before performing procedures on humans [24]. However, current computer-based simulations have lots of drawbacks, such as unrealistic visual appearance, lacking variability, and complex creation procedures taking into account the varying anatomical properties, all of which lead to diminishing the quality of surgical training. Therefore, AI-generated surgical simulations promise significant advancements in medical education since the underlying machine-learning models can learn the anatomical and visual characteristics of surgeries as well as their interactions with surgical tools from real-world data. Similar to recent works on image-guided surgery by Ramalhinho et al. [18] and Schneider et al. [23], our work focuses on laparoscopic surgery. We propose an approach for generating realistic laparoscopic videos conditioned on both text prompts and surgical tool positions. This lays the groundwork for a dynamic and interactive surgical training platform that mimics real-world scenarios. With this approach, we achieve state-of-the-art realism with an FID score of 33.43 and a pixel-wise F1 score of 0.72 for the control of tool positions. Moreover, we successfully generate coherent videos of single surgical actions.

Recent advances unveiled physical neural networks as promising machine learning platforms, offering faster and more energy-efficient information processing. Compared with extensively-studied optical neural networks, the development of mechanical neural networks (MNNs) remains nascent and faces significant challenges, including heavy computational demands and learning with approximate gradients. Here, we introduce the mechanical analogue of in situ backpropagation to enable highly efficient training of MNNs. We demonstrate that the exact gradient can be obtained locally in MNNs, enabling learning through their immediate vicinity. With the gradient information, we showcase the successful training of MNNs for behavior learning and machine learning tasks, achieving high accuracy in regression and classification. Furthermore, we present the retrainability of MNNs involving task-switching and damage, demonstrating the resilience. Our findings, which integrate the theory for training MNNs and experimental and numerical validations, pave the way for mechanical machine learning hardware and autonomous self-learning material systems.

This technical report describes the development of WangchanLion, an instruction fine-tuned model focusing on Machine Reading Comprehension (MRC) in the Thai language. Our model is based on SEA-LION and a collection of instruction following datasets. To promote open research and reproducibility, we publicly release all training data, code, and the final model weights under the Apache-2 license. To assess the contextual understanding capability, we conducted extensive experimental studies using two Thai MRC datasets, XQuAD and Iapp_wiki_qa_squad. Experimental results demonstrate the model's ability to comprehend the context and produce an answer faithful to the reference one in 0-shot and 1-shot settings. In addition, our evaluation goes beyond the traditional MRC. We propose a new evaluation scheme assessing the answer's correctness, helpfulness, conciseness, and contextuality. Our code is available publicly at https://github.com/vistec-AI/WangchanLion.

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This bibliometric review aims to provide a panoramic view of how LLMs have been used in BHI by examining research articles and collaboration networks from 2022 to 2023. It further explores how LLMs can improve Natural Language Processing (NLP) applications in various BHI areas like medical diagnosis, patient engagement, electronic health record management, and personalized medicine. To do this, our bibliometric review identifies key trends, maps out research networks, and highlights major developments in this fast-moving field. Lastly, it discusses the ethical concerns and practical challenges of using LLMs in BHI, such as data privacy and reliable medical recommendations. Looking ahead, we consider how LLMs could further transform biomedical research as well as healthcare delivery and patient outcomes. This bibliometric review serves as a resource for stakeholders in healthcare, including researchers, clinicians, and policymakers, to understand the current state and future potential of LLMs in BHI.

Understanding the limits of language is a prerequisite for Large Language Models (LLMs) to act as theories of natural language. LLM performance in some language tasks presents both quantitative and qualitative differences from that of humans, however it remains to be determined whether such differences are amenable to model size. This work investigates the critical role of model scaling, determining whether increases in size make up for such differences between humans and models. We test three LLMs from different families (Bard, 137 billion parameters; ChatGPT-3.5, 175 billion; ChatGPT-4, 1.5 trillion) on a grammaticality judgment task featuring anaphora, center embedding, comparatives, and negative polarity. N=1,200 judgments are collected and scored for accuracy, stability, and improvements in accuracy upon repeated presentation of a prompt. Results of the best performing LLM, ChatGPT-4, are compared to results of n=80 humans on the same stimuli. We find that increased model size may lead to better performance, but LLMs are still not sensitive to (un)grammaticality as humans are. It seems possible but unlikely that scaling alone can fix this issue. We interpret these results by comparing language learning in vivo and in silico, identifying three critical differences concerning (i) the type of evidence, (ii) the poverty of the stimulus, and (iii) the occurrence of semantic hallucinations due to impenetrable linguistic reference.

Pretrained language models underpin several AI applications, but their high computational cost for training limits accessibility. Initiatives such as BLOOM and StarCoder aim to democratize access to pretrained models for collaborative community development. However, such existing models face challenges: limited multilingual capabilities, continual pretraining causing catastrophic forgetting, whereas pretraining from scratch is computationally expensive, and compliance with AI safety and development laws. This paper presents Aurora-M, a 15B parameter multilingual open-source model trained on English, Finnish, Hindi, Japanese, Vietnamese, and code. Continually pretrained from StarCoderPlus on 435 billion additional tokens, Aurora-M surpasses 2 trillion tokens in total training token count. It is the first open-source multilingual model fine-tuned on human-reviewed safety instructions, thus aligning its development not only with conventional red-teaming considerations, but also with the specific concerns articulated in the Biden-Harris Executive Order on the Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence. Aurora-M is rigorously evaluated across various tasks and languages, demonstrating robustness against catastrophic forgetting and outperforming alternatives in multilingual settings, particularly in safety evaluations. To promote responsible open-source LLM development, Aurora-M and its variants are released at https://huggingface.co/collections/aurora-m/aurora-m-models-65fdfdff62471e09812f5407 .

Voice is a natural mode of expression offered by modern computer-based systems. Qualitative perspectives on voice-based user experiences (voice UX) offer rich descriptions of complex interactions that numbers alone cannot fully represent. We conducted a systematic review of the literature on qualitative approaches to voice UX, capturing the nature of this body of work in a systematic map and offering a qualitative synthesis of findings. We highlight the benefits of qualitative methods for voice UX research, identify opportunities for increasing rigour in methods and outcomes, and distill patterns of experience across a diversity of devices and modes of qualitative praxis.

In this work, we aim to improve transparency and efficacy in human-robot collaboration by developing machine teaching algorithms suitable for groups with varied learning capabilities. While previous approaches focused on tailored approaches for teaching individuals, our method teaches teams with various compositions of diverse learners using team belief representations to address personalization challenges within groups. We investigate various group teaching strategies, such as focusing on individual beliefs or the group's collective beliefs, and assess their impact on learning robot policies for different team compositions. Our findings reveal that team belief strategies yield less variation in learning duration and better accommodate diverse teams compared to individual belief strategies, suggesting their suitability in mixed-proficiency settings with limited resources. Conversely, individual belief strategies provide a more uniform knowledge level, particularly effective for homogeneously inexperienced groups. Our study indicates that the teaching strategy's efficacy is significantly influenced by team composition and learner proficiency, highlighting the importance of real-time assessment of learner proficiency and adapting teaching approaches based on learner proficiency for optimal teaching outcomes.

This study presents a comprehensive analysis and comparison of two predominant fine-tuning methodologies - full-parameter fine-tuning and parameter-efficient tuning - within the context of medical Large Language Models (LLMs). We developed and refined a series of LLMs, based on the Llama-2 architecture, specifically designed to enhance medical knowledge retrieval, reasoning, and question-answering capabilities. Our experiments systematically evaluate the effectiveness of these tuning strategies across various well-known medical benchmarks. Notably, our medical LLM Med42 showed an accuracy level of 72% on the US Medical Licensing Examination (USMLE) datasets, setting a new standard in performance for openly available medical LLMs. Through this comparative analysis, we aim to identify the most effective and efficient method for fine-tuning LLMs in the medical domain, thereby contributing significantly to the advancement of AI-driven healthcare applications.

We use an LLM named PaLM 2 to generate training data given a noisy human-authored course description input as input. We use this data to train several different smaller language models to predict SDGs for university courses. This work contributes to better university level adaptation of SDGs. The best performing model in our experiments was BART with an F1-score of 0.786.