We present a local learning rule in which Hebbian learning is conditional on an incorrect prediction of a reinforcement signal. We propose a biological interpretation of such a framework and display its utility through examples in which the reinforcement signal is cast as the delivery of a neuromodulator to its target. Three exam pIes are presented which illustrate how this framework can be applied to the development of the oculomotor system. 1 INTRODUCTION Activity-dependent accounts of the self-organization of the vertebrate brain have relied ubiquitously on correlational (mainly Hebbian) rules to drive synaptic learning. In the brain, a major problem for any such unsupervised rule is that many different kinds of correlations exist at approximately the same time scales and each is effectively noise to the next. For example, relationships within and between the retinae among variables such as color, motion, and topography may mask one another and disrupt their appropriate segregation at the level of the thalamus or cortex.

IR is typically a sigmoidal function such as (1.2) but other choices than (1.2) are possible and of interest.

Human VlSlon systems integrate information nonlocally, across long spatial ranges. For example, a moving stimulus appears smeared when viewed briefly (30 ms), yet sharp when viewed for a longer exposure (100 ms) (Burr, 1980). This suggests that visual systems combine information along a trajectory that matches the motion of the stimulus. Our self-organizing neural network model shows how developmental exposure to moving stimuli can direct the formation of horizontal trajectory-specific motion integration pathways that unsmear representations of moving stimuli. These results account for Burr's data and can potentially also model ot.her phenomena, such as visual inertia. 1 INTRODUCTION N onlocal interactions strongly influence the processing of visual motion information and the response characteristics of visual neurons. Examples include: attentional modulation of receptive field shape; modulation of neural response by stimuli beyond the classical receptive field; and neural response to large-field background motion. In this paper we present a model of the development of nonlocal neural mechanisms for visual motion processing.

Two theorems and a lemma are presented about the use of jackknife estimator and the cross-validation method for model selection. Theorem 1 gives the asymptotic form for the jackknife estimator. Combined with the model selection criterion, this asymptotic form can be used to obtain the fit of a model. The model selection criterion we used is the negative of the average predictive likehood, the choice of which is based on the idea of the cross-validation method. Lemma 1 provides a formula for further exploration of the asymptotics of the model selection criterion. Theorem 2 gives an asymptotic form of the model selection criterion for the regression case, when the parameters optimization criterion has a penalty term. Theorem 2 also proves the asymptotic equivalence of Moody's model selection criterion (Moody, 1992) and the cross-validation method, when the distance measure between response y and regression function takes the form of a squared difference. 1 INTRODUCTION Selecting a model for a specified problem is the key to generalization based on the training data set.

How can artificial neural nets generalize better from fewer examples? In order to generalize successfully, neural network learning methods typically require large training data sets. We introduce a neural network learning method that generalizes rationally from many fewer data points, relying instead on prior knowledge encoded in previously learned neural networks. For example, in robot control learning tasks reported here, previously learned networks that model the effects of robot actions are used to guide subsequent learning of robot control functions. For each observed training example of the target function (e.g. the robot control policy), the learner explains the observed example in terms of its prior knowledge, then analyzes this explanation to infer additional information about the shape, or slope, of the target function. This shape knowledge is used to bias generalization when learning the target function. Results are presented applying this approach to a simulated robot task based on reinforcement learning.

So far there has been no general method for relating extracellular electrophysiological measured activity of neurons in the associative cortex to underlying network or "cognitive" states. We propose to model such data using a multivariate Poisson Hidden Markov Model. We demonstrate the application of this approach for temporal segmentation of the firing patterns, and for characterization of the cortical responses to external stimuli. Using such a statistical model we can significantly discriminate two behavioral modes of the monkey, and characterize them by the different firing patterns, as well as by the level of coherency of their multi-unit firing activity. Our study utilized measurements carried out on behaving Rhesus monkeys by M. Abeles, E. Vaadia, and H. Bergman, of the Hadassa Medical School of the Hebrew University. 1 Introduction Hebb hypothesized in 1949 that the basic information processing unit in the cortex is a cell-assembly which may include thousands of cells in a highly interconnected network[l].

A boosting algorithm converts a learning machine with error rate less than 50% to one with an arbitrarily low error rate. However, the algorithm discussed here depends on having a large supply of independent training samples. We show how to circumvent this problem and generate an ensemble of learning machines whose performance in optical character recognition problems is dramatically improved over that of a single network. We report the effect of boosting on four databases (all handwritten) consisting of 12,000 digits from segmented ZIP codes from the United State Postal Service (USPS) and the following from the National Institute of Standards and Testing (NIST): 220,000 digits, 45,000 upper case alphas, and 45,000 lower case alphas. We use two performance measures: the raw error rate (no rejects) and the reject rate required to achieve a 1% error rate on the patterns not rejected.

The algorithm presented performs gradient descent on the weight space of an Artificial Neural Network (ANN), using a finite difference to approximate the gradient The method is novel in that it achieves a computational complexity similar to that of Node Perturbation, O(N3), but does not require access to the activity of hidden or internal neurons. This is possible due to a stochastic relation between perturbations at the weights and the neurons of an ANN. The algorithm is also similar to Weight Perturbation in that it is optimal in terms of hardware requirements when used for the training ofVLSI implementations of ANN's.

We have designed an architecture to span the gap between biophysics and cognitive science to address and explore issues of how a discrete symbol processing system can arise from the continuum, and how complex dynamics like oscillation and synchronization can then be employed in its operation and affect its learning. We show how a discrete-time recurrent "Elman" network architecture can be constructed from recurrently connected oscillatory associative memory modules described by continuous nonlinear ordinary differential equations. The modules can learn connection weights between themselves which will cause the system to evolve under a clocked "machine cycle" by a sequence of transitions of attractors within the modules, much as a digital computer evolves by transitions of its binary flip-flop attractors. The architecture thus employs the principle of "computing with attractors" used by macroscopic systems for reliable computation in the presence of noise. We have specifically constructed a system which functions as a finite state automaton that recognizes or generates the infinite set of six symbol strings that are defined by a Reber grammar. It is a symbol processing system, but with analog input and oscillatory subsymbolic representations. The time steps (machine cycles) of the system are implemented by rhythmic variation (clocking) of a bifurcation parameter. This holds input and "context" modules clamped at their attractors while'hidden and output modules change state, then clamps hidden and output states while context modules are released to load those states as the new context for the next cycle of input. Superior noise immunity has been demonstrated for systems with dynamic attractors over systems with static attractors, and synchronization ("binding") between coupled oscillatory attractors in different modules has been shown to be important for effecting reliable transitions.

The formation of propagating spiral waves is studied in a randomly connected neural network composed of integrate-and-fire neurons with recovery period and excitatory connections using computer simulations. Network activity is initiated by periodic stimulation at a single point. The results suggest that spiral waves can arise in such a network via a sub-critical Hopf bifurcation. 1 Introduction