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CURENet: Combining Unified Representations for Efficient Chronic Disease Prediction
Dao, Cong-Tinh, Phan, Nguyen Minh Thao, Ding, Jun-En, Wu, Chenwei, Restrepo, David, Luo, Dongsheng, Zhao, Fanyi, Liao, Chun-Chieh, Peng, Wen-Chih, Wang, Chi-Te, Chen, Pei-Fu, Chen, Ling, Ju, Xinglong, Liu, Feng, Hung, Fang-Ming
Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to form a comprehensive view of a patient's health, which is crucial for informed therapeutic decision-making. Yet, most predictive models fail to fully capture the interactions, redundancies, and temporal patterns across multiple data modalities, often focusing on a single data type or overlooking these complexities. In this paper, we present CURENet, a multimodal model (Combining Unified Representations for Efficient chronic disease prediction) that integrates unstructured clinical notes, lab tests, and patients' time-series data by utilizing large language models (LLMs) for clinical text processing and textual lab tests, as well as transformer encoders for longitudinal sequential visits. CURENet has been capable of capturing the intricate interaction between different forms of clinical data and creating a more reliable predictive model for chronic illnesses. We evaluated CURENet using the public MIMIC-III and private FEMH datasets, where it achieved over 94\% accuracy in predicting the top 10 chronic conditions in a multi-label framework. Our findings highlight the potential of multimodal EHR integration to enhance clinical decision-making and improve patient outcomes.
Oya: Deep Learning for Accurate Global Precipitation Estimation
Brempong, Emmanuel Asiedu, Hassen, Mohammed Alewi, MohamedKhair, MohamedElfatih, Dube, Vusumuzi, Potes, Santiago Hincapie, Graham, Olivia, Brik, Amanie, McGovern, Amy, Huffman, George J., Hickey, Jason
Accurate precipitation estimation is critical for hydrological applications, especially in the Global South where ground-based observation networks are sparse and forecasting skill is limited. Existing satellite-based precipitation products often rely on the longwave infrared channel alone or are calibrated with data that can introduce significant errors, particularly at sub-daily timescales. This study introduces Oya, a novel real-time precipitation retrieval algorithm utilizing the full spectrum of visible and infrared (VIS-IR) observations from geostationary (GEO) satellites. Oya employs a two-stage deep learning approach, combining two U-Net models: one for precipitation detection and another for quantitative precipitation estimation (QPE), to address the inherent data imbalance between rain and no-rain events. The models are trained using high-resolution GPM Combined Radar-Radiometer Algorithm (CORRA) v07 data as ground truth and pre-trained on IMERG-Final retrievals to enhance robustness and mitigate overfitting due to the limited temporal sampling of CORRA. By leveraging multiple GEO satellites, Oya achieves quasi-global coverage and demonstrates superior performance compared to existing competitive regional and global precipitation baselines, offering a promising pathway to improved precipitation monitoring and forecasting.
A Style is Worth One Code: Unlocking Code-to-Style Image Generation with Discrete Style Space
Liu, Huijie, Cui, Shuhao, Cao, Haoxiang, Ma, Shuai, Wu, Kai, Kang, Guoliang
Innovative visual stylization is a cornerstone of artistic creation, yet generating novel and consistent visual styles remains a significant challenge. Existing generative approaches typically rely on lengthy textual prompts, reference images, or parameter-efficient fine-tuning to guide style-aware image generation, but often struggle with style consistency, limited creativity, and complex style representations. In this paper, we affirm that a style is worth one numerical code by introducing the novel task, code-to-style image generation, which produces images with novel, consistent visual styles conditioned solely on a numerical style code. To date, this field has only been primarily explored by the industry (e.g., Midjourney), with no open-source research from the academic community. To fill this gap, we propose CoTyle, the first open-source method for this task. Specifically, we first train a discrete style codebook from a collection of images to extract style embeddings. These embeddings serve as conditions for a text-to-image diffusion model (T2I-DM) to generate stylistic images. Subsequently, we train an autoregressive style generator on the discrete style embeddings to model their distribution, allowing the synthesis of novel style embeddings. During inference, a numerical style code is mapped to a unique style embedding by the style generator, and this embedding guides the T2I-DM to generate images in the corresponding style. Unlike existing methods, our method offers unparalleled simplicity and diversity, unlocking a vast space of reproducible styles from minimal input. Extensive experiments validate that CoTyle effectively turns a numerical code into a style controller, demonstrating a style is worth one code.
Generalizing Analogical Inference from Boolean to Continuous Domains
Cunha, Francisco, Lepage, Yves, Couceiro, Miguel, Bouraoui, Zied
Analogical reasoning is a powerful inductive mechanism, widely used in human cognition and increasingly applied in artificial intelligence. Formal frameworks for analogical inference have been developed for Boolean domains, where inference is provably sound for affine functions and approximately correct for functions close to affine. These results have informed the design of analogy-based classifiers. However, they do not extend to regression tasks or continuous domains. In this paper, we revisit analogical inference from a foundational perspective. We first present a counterexample showing that existing generalization bounds fail even in the Boolean setting. We then introduce a unified framework for analogical reasoning in real-valued domains based on parameterized analogies defined via generalized means. This model subsumes both Boolean classification and regression, and supports analogical inference over continuous functions. We characterize the class of analogy-preserving functions in this setting and derive both worst-case and average-case error bounds under smoothness assumptions. Our results offer a general theory of analogical inference across discrete and continuous domains.
RI-Loss: A Learnable Residual-Informed Loss for Time Series Forecasting
Wang, Jieting, Shang, Xiaolei, Li, Feijiang, Peng, Furong
Time series forecasting relies on predicting future values from historical data, yet most state-of-the-art approaches-including transformer and multilayer perceptron-based models-optimize using Mean Squared Error (MSE), which has two fundamental weaknesses: its point-wise error computation fails to capture temporal relationships, and it does not account for inherent noise in the data. To overcome these limitations, we introduce the Residual-Informed Loss (RI-Loss), a novel objective function based on the Hilbert-Schmidt Independence Criterion (HSIC). RI-Loss explicitly models noise structure by enforcing dependence between the residual sequence and a random time series, enabling more robust, noise-aware representations. Theoretically, we derive the first non-asymptotic HSIC bound with explicit double-sample complexity terms, achieving optimal convergence rates through Bernstein-type concentration inequalities and Rademacher complexity analysis. This provides rigorous guarantees for RI-Loss optimization while precisely quantifying kernel space interactions. Empirically, experiments across eight real-world benchmarks and five leading forecasting models demonstrate improvements in predictive performance, validating the effectiveness of our approach. The code is publicly available at: https://github.com/shang-xl/RI-Loss.
MIRNet: Integrating Constrained Graph-Based Reasoning with Pre-training for Diagnostic Medical Imaging
Kong, Shufeng, Wang, Zijie, Cui, Nuan, Tang, Hao, Meng, Yihan, Wei, Yuanyuan, Chen, Feifan, Wang, Yingheng, Cai, Zhuo, Wang, Yaonan, Zhang, Yulong, Li, Yuzheng, Zheng, Zibin, Liu, Caihua, Liang, Hao
We introduce MIRNet (Medical Image Reasoner Network), a novel framework that integrates self-supervised pre-training with constrained graph-based reasoning. Tongue image diagnosis is a particularly challenging domain that requires fine-grained visual and semantic understanding. Our approach leverages self-supervised masked autoencoder (MAE) to learn transferable visual representations from unlabeled data; employs graph attention networks (GA T) to model label correlations through expert-defined structured graphs; enforces clinical priors via constraint-aware optimization using KL divergence and regularization losses; and mitigates imbalance using asymmetric loss (ASL) and boosting ensembles. To address annotation scarcity, we also introduce TongueAtlas-4K, a comprehensive expert-curated benchmark comprising 4,000 images annotated with 22 diagnostic labels-representing the largest public dataset in tongue analysis. V alidation shows our method achieves state-of-the-art performance.
EEGAgent: A Unified Framework for Automated EEG Analysis Using Large Language Models
Zhao, Sha, Peng, Mingyi, Jiang, Haiteng, Li, Tao, Li, Shijian, Pan, Gang
Scalable and generalizable analysis of brain activity is essential for advancing both clinical diagnostics and cognitive research. Electroencephalography (EEG), a non-invasive modality with high temporal resolution, has been widely used for brain states analysis. However, most existing EEG models are usually tailored for individual specific tasks, limiting their utility in realistic scenarios where EEG analysis often involves multi-task and continuous reasoning. In this work, we introduce EEGAgent, a general-purpose framework that leverages large language models (LLMs) to schedule and plan multiple tools to automatically complete EEG-related tasks. EEGAgent is capable of performing the key functions: EEG basic information perception, spatiotemporal EEG exploration, EEG event detection, interaction with users, and EEG report generation. To realize these capabilities, we design a toolbox composed of different tools for EEG prepro-cessing, feature extraction, event detection, etc. These capabilities were evaluated on public datasets, and our EEGAgent can support flexible and interpretable EEG analysis, highlighting its potential for real-world clinical applications.
iSeal: Encrypted Fingerprinting for Reliable LLM Ownership Verification
Xiong, Zixun, Wu, Gaoyi, Yu, Qingyang, Ma, Mingyu Derek, Yao, Lingfeng, Pan, Miao, Du, Xiaojiang, Wang, Hao
Given the high cost of large language model (LLM) training from scratch, safeguarding LLM intellectual property (IP) has become increasingly crucial. As the standard paradigm for IP ownership verification, LLM fingerprinting thus plays a vital role in addressing this challenge. Existing LLM fingerprinting methods verify ownership by extracting or injecting model-specific features. However, they overlook potential attacks during the verification process, leaving them ineffective when the model thief fully controls the LLM's inference process. In such settings, attackers may share prompt-response pairs to enable fingerprint unlearning, or manipulate outputs to evade exact-match verification. We propose iSeal, the first fingerprinting method designed for reliable verification when the model thief controls the suspected LLM in an end-to-end manner. It injects unique features into both the model and an external module, reinforced by an error-correction mechanism and a similarity-based verification strategy. These components are resistant to verification-time attacks, including collusion-based fingerprint unlearning and response manipulation, backed by both theoretical analysis and empirical results.
Weaver: Kronecker Product Approximations of Spatiotemporal Attention for Traffic Network Forecasting
Cheong, Christopher, Davis, Gary, Choi, Seongjin
Spatiotemporal forecasting on transportation networks is a complex task that requires understanding how traffic nodes interact within a dynamic, evolving system dictated by traffic flow dynamics and social behavioral patterns. The importance of transportation networks and ITS for modern mobility and commerce necessitates forecasting models that are not only accurate but also interpretable, efficient, and robust under structural or temporal perturbations. Recent approaches, particularly Transformer-based architectures, have improved predictive performance but often at the cost of high computational overhead and diminished architectural interpretability. In this work, we introduce Weaver, a novel attention-based model that applies Kronecker product approximations (KPA) to decompose the PN X PN spatiotemporal attention of O(P^2N^2) complexity into local P X P temporal and N X N spatial attention maps. This Kronecker attention map enables our Parallel-Kronecker Matrix-Vector product (P2-KMV) for efficient spatiotemporal message passing with O(P^2N + N^2P) complexity. To capture real-world traffic dynamics, we address the importance of negative edges in modeling traffic behavior by introducing Valence Attention using the continuous Tanimoto coefficient (CTC), which provides properties conducive to precise latent graph generation and training stability. To fully utilize the model's learning capacity, we introduce the Traffic Phase Dictionary for self-conditioning. Evaluations on PEMS-BAY and METR-LA show that Weaver achieves competitive performance across model categories while training more efficiently.
Mina: A Multilingual LLM-Powered Legal Assistant Agent for Bangladesh for Empowering Access to Justice
Wasi, Azmine Toushik, Faisal, Wahid, Islam, Mst Rafia
Bangladesh's low-income population faces major barriers to affordable legal advice due to complex legal language, procedural opacity, and high costs. Existing AI legal assistants lack Bengali-language support and jurisdiction-specific adaptation, limiting their effectiveness. To address this, we developed Mina, a multilingual LLM-based legal assistant tailored for the Bangladeshi context. It employs multilingual embeddings and a RAG-based chain-of-tools framework for retrieval, reasoning, translation, and document generation, delivering context-aware legal drafts, citations, and plain-language explanations via an interactive chat interface. Evaluated by law faculty from leading Bangladeshi universities across all stages of the 2022 and 2023 Bangladesh Bar Council Exams, Mina scored 75-80% in Preliminary MCQs, Written, and simulated Viva Voce exams, matching or surpassing average human performance and demonstrating clarity, contextual understanding, and sound legal reasoning. Even under a conservative upper bound, Mina operates at just 0.12-0.61% of typical legal consultation costs in Bangladesh, yielding a 99.4-99.9\% cost reduction relative to human-provided services. These results confirm its potential as a low-cost, multilingual AI assistant that automates key legal tasks and scales access to justice, offering a real-world case study on building domain-specific, low-resource systems and addressing challenges of multilingual adaptation, efficiency, and sustainable public-service AI deployment.